234 results match your criteria: "Institute for Pain Research[Affiliation]"
Reporting missing participant data in randomised trials: systematic survey of the methodological literature and a proposed guide.
BMJ Open
December 2015
Department of Clinical Epidemiology & Biostatistics, McMaster University, Hamilton, Ontario, Canada Department of Medicine, McMaster University, Hamilton, Ontario, Canada.
Objectives: We conducted a systematic survey of the methodological literature to identify recommended approaches for how and what randomised clinical trial (RCT) authors should report on missing participant data and, on the basis of these approaches, to propose guidance for RCT authors.
Methods: We defined missing participant data (MPD) as missing outcome data for trial participants. We considered both categorical and continuous outcome data.
Ketamine added to morphine or hydromorphone patient-controlled analgesia for acute postoperative pain in adults: a systematic review and meta-analysis of randomized trials.
Can J Anaesth
March 2016
Centre for Medical Evidence, Decision Integrity and Clinical Impact (MEDICI), Western University, London, ON, Canada.
Purpose: To determine whether ketamine added to morphine or hydromorphone patient-controlled analgesia (PCA) provides clinically relevant reductions in postoperative pain, opioid requirements, and adverse events when compared with morphine or hydromorphone PCA in adults undergoing surgery.
Source: We systematically searched six databases up to June 2, 2015 for randomized controlled trials (RCTs) comparing ketamine plus morphine/hydromorphone PCA vs morphine/hydromorphone PCA for postoperative pain in adults.
Principal Findings: Thirty-six RCTs including 2,502 patients proved eligible, and 22 of these were at low risk of bias.
Planning and reporting of quality-of-life outcomes in cancer trials.
Ann Oncol
January 2016
Basel Institute for Clinical Epidemiology and Biostatistics, University Hospital of Basel, Switzerland Department of Oncology, University Hospital of Basel, Switzerland Department of Medical Oncology, Royal Marsden Hospital, London, UK.
Systematic reviews experience major limitations in reporting absolute effects.
J Clin Epidemiol
April 2016
Department of Clinical Epidemiology & Biostatistics, McMaster University, 1280 Main Street West, Hamilton, Ontario L8S 4K1, Canada; Department of Medicine, McMaster University, 1280 Main St W, Hamilton, Ontario L8S 4L8, Canada.
Objectives: Expressing treatment effects in relative terms yields larger numbers than expressions in absolute terms, affecting the judgment of the clinicians and patients regarding the treatment options. It is uncertain how authors of systematic reviews (SRs) absolute effect estimates are reported in. We therefore undertook a systematic survey to identify and describe the reporting and methods for calculating absolute effect estimates in SRs.
View Article and Find Full Text PDFPremature Discontinuation of Randomized Trials in Critical and Emergency Care: A Retrospective Cohort Study.
Crit Care Med
January 2016
1Department of Clinical Research, Basel Institute for Clinical Epidemiology and Biostatistics, University Hospital Basel, Basel, Switzerland.2Department of Medicine, Academy of Swiss Insurance Medicine, University Hospital Basel, Basel, Switzerland.3Cochrane Switzerland, Institute of Social and Preventive Medicine (IUMSP), Lausanne University Hospital, Lausanne, Switzerland.4Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada.5Department of Medicine, McMaster University, Hamilton, Ontario, Canada.6German Cochrane Centre, Medical Center-University of Freiburg, Freiburg, Germany.7Epidemiology, Biostatistics and Prevention Institute, University of Zurich, Zurich, Switzerland.8Centre de Recherche Clinique du Centre Hospitalier Universitaire de Sherbrooke, Université de Sherbrooke, Sherbrooke, Canada.9Department of Health and Society, Austrian Federal Institute for Health Care, Vienna, Austria.10Departments of Urology and Public Health, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.11Department of Internal Medicine, Pontificia Universidad Catolica de Chile, Santiago, Chile.12Evidence-Based Dentistry Unit, Faculty of Dentistry, Universidad de Chile, Santiago, Chile.13Michael G. DeGroote Institute for Infectious Diseases Research, McMaster University, Hamilton, Ontario, Canada.14Department of Internal Medicine, American University of Beirut, Beirut, Lebanon.15Department of Medicine, State University of New York at Buffalo, Buffalo, NY.16Chinese Evidence-Based Medicine Center, West China Hospital, Sichuan University, Chengdu, China.17Department of Neonatology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.18Department of Anesthesia, McMaster University, Hamilton, Ontario, Canada.19Michael G. DeGroote Institute for Pain Research and Care, McMaster University, Hamilton, Ontario, Canada.20Epidemiology Unit, Department of Cardiology, Vall d'Hebron Hospital and CIBER de Epidem
Objectives: Randomized clinical trials that enroll patients in critical or emergency care (acute care) setting are challenging because of narrow time windows for recruitment and the inability of many patients to provide informed consent. To assess the extent that recruitment challenges lead to randomized clinical trial discontinuation, we compared the discontinuation of acute care and nonacute care randomized clinical trials.
Design: Retrospective cohort of 894 randomized clinical trials approved by six institutional review boards in Switzerland, Germany, and Canada between 2000 and 2003.
Characteristics of patients receiving long-term opioid therapy for chronic noncancer pain: a cross-sectional survey of patients attending the Pain Management Centre at Hamilton General Hospital, Hamilton, Ontario.
CMAJ Open
October 2015
Michael G. DeGroote Institute for Pain Research and Care, McMaster University, Hamilton, Ont. ; Department of Anesthesia, McMaster University, Hamilton, Ont.
Background: Characteristics of patients receiving long-term opioid therapy (≥ 6 months) for chronic noncancer pain are poorly understood. We conducted a cross-sectional survey of this patient population to explore demographic variables, pain relief, functional improvement, adverse effects and impressions of an educational pamphlet on long-term opioid therapy.
Methods: We invited 260 adult patients presenting to the Pain Management Centre at the Hamilton General Hospital, Hamilton, Ontario, with chronic noncancer pain to complete a 20-item survey.
Reporting, handling and assessing the risk of bias associated with missing participant data in systematic reviews: a methodological survey.
BMJ Open
September 2015
Iberoamerican Cochrane Centre, Biomedical Research Institute Sant Pau-CIBER of Epidemiology and Public Health (CIBERESP- IIB Sant Pau), Barcelona, Spain.
Objectives: To describe how systematic reviewers are reporting missing data for dichotomous outcomes, handling them in the analysis and assessing the risk of associated bias.
Methods: We searched MEDLINE and the Cochrane Database of Systematic Reviews for systematic reviews of randomised trials published in 2010, and reporting a meta-analysis of a dichotomous outcome. We randomly selected 98 Cochrane and 104 non-Cochrane systematic reviews.
Current State of Reporting Pain Outcomes in Cochrane Reviews of Chronic Musculoskeletal Pain Conditions and Considerations for an OMERACT Research Agenda.
J Rheumatol
October 2015
From the Ottawa Hospital Research Institute, Centre for Practice-Changing Research, Ottawa, Canada; School of Epidemiology, Public Health and Preventive Medicine, University of Ottawa and Cardiovascular Research Methods Centre, University of Ottawa Heart Institute, Ottawa, Canada; SDG LLC Cambridge, MA, USA; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds and NIHR Leeds Musculoskeletal Biomedical Research Unit, Leeds, UK; University of Ottawa; Institute of Population Health, University of Ottawa, Ottawa; Institute for Work & Health, Toronto, Canada; Division of Rheumatology, Department of Medicine, Johns Hopkins University, Baltimore, MD, USA; Department of Anesthesia, Department of Clinical Epidemiology and Biostatistics, and the Michael G. DeGroote Institute for Pain Research and Care, McMaster University, Hamilton, Canada; Musculoskeletal Statistics Unit, The Parker Institute, Department of Rheumatology, Bispebjerg and Frederiksberg Hospital, Copenhagen, Denmark; Quintiles, Inc., Division of Rheumatology, Department of Medicine, Duke University School of Medicine, Durham, NC, USA; Institute of Primary Health Care (BIHAM), University of Bern, Bern, Switzerland; University Hospital Carl Gustav Carus, Dresden, Germany; University of Washington, Seattle, WA, USA; Department of Health Sciences (VU University) and Department of Epidemiology and Biostatistics (VU University Medical Centre) of the EMGO Institute for Health and Care Research, Amsterdam, The Netherlands; Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA; Laboratory for Pain Research, University of Split School of Medicine, Split, Croatia; Birmingham Veterans Affairs Medical Center and University of Alabama at Birmingham, Birmingham, AL, USA; Division Immunology/Rheumatology Stanford University School of Medicine, Palo Alto, CA, USA; Institute of Infection and Immunity, Cardiff University, Cardiff, UK; Department of Epidemiology and Biostatistics and the EMGO Institute for Health and Care Research, VU University Medical Center Amsterdam, Amsterdam, The Netherlands; University of Ottawa, Department of Medicine, Faculty of Medicine, Ottawa Hospital Research Institute; Clinical Epidemiology Program, University of Ottawa and School of Epidemiology, Public Health and Preventive Medicine, University of Ottawa; Faculty of Medicine, Institute of Population Health, Ottawa, Canada.
Objective: To assess the current state of reporting of pain outcomes in Cochrane reviews on chronic musculoskeletal painful conditions and to elicit opinions of patients, healthcare practitioners, and methodologists on presenting pain outcomes to patients, clinicians, and policymakers.
Methods: We identified all reviews in the Cochrane Library of chronic musculoskeletal pain conditions from Cochrane review groups (Back, Musculoskeletal, and Pain, Palliative, and Supportive Care) that contained a summary of findings (SoF) table. We extracted data on reported pain domains and instruments and conducted a survey and interviews on considerations for SoF tables (e.
Management of Central Poststroke Pain: Systematic Review of Randomized Controlled Trials.
Stroke
October 2015
From the Departments of Clinical Epidemiology and Biostatistics (S.M.M., R.K., Z.I., L.T., G.H.G., J.W.B.), Anesthesia (D.N.B., L.T., J.W.B.), Medicine (A.P., G.H.G.), and Pediatrics (L.T.) and Michael G. DeGroote Institute for Pain Research and Care (L.W., R.C., D.N.B., A.P., S.M.K., J.W.B.), McMaster University, Hamilton, Ontario, Canada; Outcomes Research Consortium, Cleveland, OH (S.M.M.); Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada (A.A.); Departments of Clinical Neurological Sciences and Oncology, Western University, London, Ontario, Canada (D.E.M.); Department of Outcomes Research, Cleveland Clinic, OH (A.T., D.I.S.); and Knowledge and Evaluation Research Unit, Divisions of Endocrinology and Diabetes, and Health Care and Policy Research, Mayo Clinic, Rochester, MN (V.M.M.).
Background And Purpose: Central poststroke pain is a chronic neuropathic disorder that follows a stroke. Current research on its management is limited, and no review has evaluated all therapies for central poststroke pain.
Methods: We conducted a systematic review of randomized controlled trials to evaluate therapies for central poststroke pain.
Association of worker characteristics and early reimbursement for physical therapy, chiropractic and opioid prescriptions with workers' compensation claim duration, for cases of acute low back pain: an observational cohort study.
BMJ Open
August 2015
Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada.
Objective: To assess the association between early reimbursement for physiotherapy, chiropractic and opioid prescriptions for acute low back pain (LBP) with disability claim duration.
Design: Observational cohort study.
Setting And Participants: From a random sample of 6665 claims for acute, uncomplicated LBP approved by the Ontario Workplace Safety and Insurance Board (WSIB) in 2005, we analysed 1442 who remained on full benefits at 4 weeks after claim approval.
Attitudes towards evaluation of psychiatric disability claims: a survey of Swiss stakeholders.
Swiss Med Wkly
March 2016
Swiss Academy of Insurance Medicine, University of Basel Hospital, Basel, Switzerland.
Questions: In Switzerland, evaluation of work capacity in individuals with mental disorders has come under criticism. We surveyed stakeholders about their concerns and expectations of the current claim process.
Methods: We conducted a nationwide online survey among five stakeholder groups.
Depressive-like behaviours and decreased dendritic branching in the medial prefrontal cortex of mice with tumors: A novel validated model of cancer-induced depression.
Behav Brain Res
November 2015
Department of Pathology & Molecular Medicine, McMaster University, Hamilton, ON L8N 3Z5, Canada; Michael G. DeGroote Institute for Pain Research and Care, McMaster University, Hamilton, ON L8N 3Z5, Canada. Electronic address:
Depression is commonly comorbid in cancer patients and has detrimental effects on disease progression. Evidence suggests that biological mechanisms may induce the onset of cancer-induced depression (CID). The present investigation aims to establish a validated preclinical animal model of CID.
View Article and Find Full Text PDFOPTIMa Review Suffered From High Risk of Selection Bias, and Misinterpreted Prior Findings.
Clin J Pain
December 2015
Departments of *Clinical Epidemiology and Biostatistics †Anesthesia ∥The Michael G. DeGroote Institute for Pain Research and Care #Faculty of Medicine, McMaster University, Hamilton §Department of Anaesthesia & Pain Medicine, Hospital for Sick Children ¶Department of Trauma and Orthopaedics University Health Network,Toronto, ON, Canada ‡Meta-Research Innovation Center at Stanford, Stanford University, Stanford, CA.
Reporting of IMMPACT-recommended core outcome domains among trials assessing opioids for chronic non-cancer pain.
Pain
September 2015
Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, ON, Canada Outcomes Research Consortium, Cleveland, OH, USA Faculty of Science, McMaster University, Hamilton, ON, Canada Pharmaceutical Sciences Postgraduate Course, University of Sorocaba, Sao Paulo, Brazil Swiss Academy of Insurance Medicine, University Hospital Basel, Basel, Switzerland Basel Institute for Clinical Epidemiology and Biostatistics, University Hospital Basel, Basel, Switzerland Department of Family Medicine, McMaster University, Hamilton, ON, Canada Institute of Health and Society, Faculty of Medicine, University of Oslo, Oslo, Norway Accident and Emergency Department, Tseung Kwan O Hospital, Hong Kong, China Accident and Emergency Department, Tuen Mun Hospital, Hong Kong, China Department of Anesthesia, McMaster University, Hamilton, ON, Canada Stanford Prevention Research Center, Department of Medicine, Stanford University, Stanford, CA, USA Department of Anesthesia and Pain Medicine, The Hospital for Sick Children, Toronto, ON, Canada Institute for Health Policy, Management and Evaluation, University of Toronto, Toronto, ON, Canada Child Health Evaluative Sciences, The Hospital for Sick Children Research Institute, Toronto, ON, Canada Department of Anesthesia, University of Calgary, Calgary, AB, Canada Department of Dentistry, Santo Tomas University, Bogota, Colombia Department of Anesthesia, University Hospital Basel, Basel, Switzerland Michael G. DeGroote Institute for Pain Research and Care, McMaster University, Hamilton, ON, Canada Department of Outcomes Research, Cleveland Clinic, Cleveland, OH, USA Department of Medicine, McMaster University, Hamilton, ON, Canada.
The Initiative on Methods, Measurement, and Pain Assessment in Clinical Trials (IMMPACT) has recommended that trialists evaluating treatments for chronic pain should consider reporting 9 patient-important outcome domains. We examined the extent to which clinical trials evaluating the effect of opioids for chronic non-cancer pain (CNCP) report outcome domains recommended by IMMPACT. We systematically searched electronic databases for English-language studies that randomized patients with CNCP to receive an opioid or a non-opioid control.
View Article and Find Full Text PDFOptimal Strategies for Reporting Pain in Clinical Trials and Systematic Reviews: Recommendations from an OMERACT 12 Workshop.
J Rheumatol
October 2015
From the Michael G. DeGroote Institute for Pain Research and Care, McMaster University; Department of Anesthesia, McMaster University; Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario; Department of Medicine, McGill University, Divisions of Rheumatology and Clinical Epidemiology, Royal Victoria Hospital, Montreal, Quebec, Canada; Paris Descartes University, APHP Cochin Hospital, Rheumatology Department, Cochin Hospital, INSERM (U1153) Clinical Epidemiology and Biostatistics, PRES Sorbonne Paris-Cité, Paris, France; The Hospital for Sick Children Research Institute, Toronto; Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto; Department of Anesthesia and Pain Medicine, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada; University of Bristol Academic Rheumatology Unit, Bristol Royal Infirmary, Bristol, UK; University of Pittsburgh and Veterans Affairs (VA) Pittsburgh Healthcare System, Pittsburgh, Pennsylvania, USA; Institute of Population Health, University of Ottawa, Ottawa, Ontario, Canada; Pain Research, University of Oxford, Nuffield Division of Anaesthetics, The Churchill, Oxford, UK; Birmingham VA Medical Center and University of Alabama at Birmingham, Birmingham, Alabama; Inflammation and Immunology Clinical Research, Celgene Corporation, Summit, New Jersey; Department of Medicine, Division of Rheumatology, the State University of New Jersey, New Brunswick, New Jersey; Division of Immunology/Rheumatology, Stanford University, Palo Alto, California; University of Texas MD Anderson Cancer Center, Houston, Texas, USA; Department of Medicine, Faculty of Medicine, Institute of Population Health, University of Ottawa; Ottawa Hospital Research Institute, Clinical Epidemiology Program; Department of Epidemiology and Community Medicine, University of Ottawa, Ottawa, Ontario, Canada.
Objective: Pain is a patient-important outcome, but current reporting in randomized controlled trials and systematic reviews is often suboptimal, impeding clinical interpretation and decision making.
Methods: A working group at the 2014 Outcome Measures in Rheumatology (OMERACT 12) was convened to provide guidance for reporting treatment effects regarding pain for individual studies and systematic reviews.
Results: For individual trials, authors should report, in addition to mean change, the proportion of patients achieving 1 or more thresholds of improvement from baseline pain (e.
The development of vaccination perspectives among chiropractic, naturopathic and medical students: a case study of professional enculturation.
Adv Health Sci Educ Theory Pract
December 2015
Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Canada.
An important influence on parents' decisions about pediatric vaccination (children under 6 years of age) is the attitude of their health care providers, including complementary and alternative medicine (CAM) providers. Very limited qualitative research exists, however, on how attitudes towards vaccination develop among healthcare professionals in-training. We explored perspective development among three groups of students: medical, chiropractic, and naturopathic.
View Article and Find Full Text PDFInhibitors of glutamate release from breast cancer cells; new targets for cancer-induced bone-pain.
Sci Rep
February 2015
Michael G. DeGroote Institute for Pain Research and Care, Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario Canada.
Glutamate is an important signaling molecule in a wide variety of tissues. Aberrant glutamatergic signaling disrupts normal tissue homeostasis and induces several disruptive pathological conditions including pain. Breast cancer cells secrete high levels of glutamate and often metastasize to bone.
View Article and Find Full Text PDFDialogue on Developing Consensus on Measurement and Presentation of Patient-important Outcomes, Using Pain Outcomes as an Exemplar, in Systematic Reviews: A Preconference Meeting at OMERACT 12.
J Rheumatol
October 2015
From Department of Medicine, Faculty of Medicine, University of Ottawa; Ottawa Hospital Research Institute, Clinical Epidemiology Program, University of Ottawa; Department of Epidemiology and Community Medicine, Faculty of Medicine, Institute of Population Health, Ottawa; Institute for Work and Health, Toronto; Department of Anesthesia, Department of Clinical Epidemiology and Biostatistics, The Michael G. DeGroote Institute for Pain Research and Care, McMaster University, Hamilton, Canada; Musculoskeletal Statistics Unit, Department of Rheumatology, The Parker Institute, Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds and the UK National Institute for Health Research (NIHR) Leeds Musculoskeletal Biomedical Research Unit, Leeds, UK; SDG LLC, Cambridge, Massachusetts, USA; VU University Medical Center, Department of Epidemiology and Biostatistics, The Netherlands; Cochrane Editorial Unit, London, UK; Cardiovascular Research Methods Centre, University of Ottawa Heart Institute, Ottawa, Canada; Department of Biostatistics, University of Liverpool, Liverpool, UK.
Prior to the Outcome Measures in Rheumatology (OMERACT) 12 meeting in Budapest, Hungary, a workshop was held bringing together individuals from a number of international outcome measure organizations to assess how best to further develop consensus on how pain is conceptualized and measured in trials of musculoskeletal conditions, and how the trials should be reported in systematic reviews.
View Article and Find Full Text PDFMeasures of Symptom Exaggeration for Mental Health Disorders: A Systematic Review.
J Insur Med
January 2015
a Department of Clinical Epidemiology & Biostatistics, McMaster University, Hamilton, Ontario, Canada.
Introduction .- Measures that help detect exaggeration of symptoms can be valuable for informing more accurate diagnoses and aid in treatment and case management. We completed a systematic review to identify measures that assess symptom exaggeration in mental health disorders.
View Article and Find Full Text PDFCopresentation of relative and absolute effects is essential to promote optimal interpretability of treatment effects.
J Clin Epidemiol
March 2015
Department of Clinical Epidemiology and Biostatistics, Faculty of Health Sciences, McMaster University, 1280 Main Street West, Hamilton, Ontario, Canada L8S 4K1.
Measuring illness beliefs in patients with lower extremity injuries: reliability and validity of the Dutch version of the Somatic Pre-Occupation and Coping questionnaire (SPOC-NL).
Injury
February 2015
Department of Trauma Surgery, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Introduction: Positive coping strategies, illness perceptions and recovery expectations are associated with better clinical outcomes and earlier return to work after injuries. The Somatic Pre-Occupation and Coping (SPOC) questionnaire captures illness beliefs and coping towards recovery of physical function and return to work after surgical treatment of tibial shaft fractures. The aim of this study was to translate and culturally adapt the SPOC into Dutch (SPOC-NL) and evaluate its reliability and validity in patients with lower extremity injuries.
View Article and Find Full Text PDFManagement of chronic neuropathic pain: a protocol for a multiple treatment comparison meta-analysis of randomised controlled trials.
BMJ Open
November 2014
Department of Clinical Epidemiology & Biostatistics, McMaster University, Hamilton, Ontario, Canada Department of Anesthesia, McMaster University, Hamilton, Ontario, Canada Michael G. DeGroote Institute for Pain Research and Care, McMaster University, Hamilton, Ontario, Canada.
Introduction: Chronic neuropathic pain is associated with reduced health-related quality of life and substantial socioeconomic costs. Current research addressing management of chronic neuropathic pain is limited. No review has evaluated all interventional studies for chronic neuropathic pain, which limits attempts to make inferences regarding the relative effectiveness of treatments.
View Article and Find Full Text PDFKnowledge Transfer within the Canadian Chiropractic Community. Part 2: Narrowing the Evidence-Practice Gap.
J Can Chiropr Assoc
September 2014
Assistant Professor and CCRF Research Chair in Neuromusculoskeletal Health, Faculty of Kinesiology and Health Studies, University of Regina.
A 45-year-old woman referred for an independent medical evaluation by her insurer.
CMAJ
November 2014
Michael G. DeGroote Institute for Pain Research and Care (Busse), Department of Anesthesia (Busse, Ebrahim) and Department of Clinical Epidemiology and Biostatistics (Busse, Ebrahim), McMaster University, Hamilton, Ont.; Faculty of Medicine (Bruun-Meyer), University of Toronto, Toronto, Ont.; Stanford Prevention Research Center, Department of Medicine (Ebrahim), Stanford University, Stanford, Calif.; Swiss Academy of Insurance Medicine, University Hospital Basel (Kunz), Basel, Switzerland.
Comparison of weight loss among named diet programs in overweight and obese adults: a meta-analysis.
JAMA
September 2014
Redwood Outcomes, Vancouver, British Columbia, Canada14Stanford Prevention Research Center, Stanford University School of Medicine, Stanford University, Stanford, California.
Importance: Many claims have been made regarding the superiority of one diet or another for inducing weight loss. Which diet is best remains unclear.
Objective: To determine weight loss outcomes for popular diets based on diet class (macronutrient composition) and named diet.