1 results match your criteria: "Institute for Molecular BioscienceThe University of QueenslandSt. LuciaQLDAustralia.[Affiliation]"
Article Synopsis
- Growth hormone (GH) is essential for liver regeneration after partial hepatectomy (PHx), with specific GH receptor (GHR) signaling pathways playing significant roles in the process.
- Mice lacking GHR showed high mortality after PHx due to increased apoptosis and innate immune cell activity, while those with intact signaling mechanisms survived and regenerated their liver normally.
- GH promotes the expression of the immunotolerance protein H2-Bl, which helps mitigate immune attacks during liver injury, indicating that HLA-G treatment could enhance recovery after liver surgeries.