444 results match your criteria: "Institute for Medical Psychology[Affiliation]"

Physical activity (PA) assessment needs tools that are inexpensive and easy to administer. Common questionnaires inquire time spent in light, moderate, and vigorous PA. However, inaccuracies may occur due to individually different understanding of PA intensity levels.

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Background: The Quality of Life of Short Stature Youth (QoLISSY) questionnaire is a patient- and parent-reported outcome measure assessing health-related quality of life (HRQOL) in short stature youth. This study evaluates the psychometric properties of the QoLISSY questionnaire within a German prospective trial of short statured children treated with human growth hormone (hGH).

Method: The instrument was administered to children with idiopathic growth hormone Deficiency (IGHD) and small for gestational age (SGA) before and after 12 month of hGH treatment.

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First-year predictors of health-related quality of life changes in short-statured children treated with human growth hormone.

J Endocrinol Invest

September 2019

Center for Psychosocial Medicine, Institute for Medical Psychology, University Medical Center Hamburg-Eppendorf, Martinistraße 52, 20246, Hamburg, Germany.

Purpose: Little attention has been directed towards examining the impact of predictors on change in health-related quality of life (HRQOL) within the course of growth hormone (GH) treatment in pediatric short stature. We aimed to assess changes in HRQOL and its sociodemographic, clinical and psychosocial predictors in children and adolescents diagnosed with growth hormone deficiency (GHD), and born short for gestational age (SGA) before and 12-month after start of GH treatment from the parents' perspective. Results were compared with an untreated group with idiopathic short stature (ISS).

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Recent findings suggest that communicative context affects the timing and magnitude of emotion effects in word processing. In particular, social attributions seem to be one important source of plasticity for the processing of affectively charged language. Here, we investigate the timing and magnitude of ERP responses toward positive, neutral, and negative trait adjectives during the anticipation of putative socio-evaluative feedback from different senders (human and computer) varying in predictability.

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Magnetic particle mapping using magnetoelectric sensors as an imaging modality.

Sci Rep

February 2019

Christian-Albrechts-Universität zu Kiel, Institute for Materials Science, Chair for Multicomponent Materials, Kiel, 24143, Germany.

Magnetic nanoparticles (MNPs) are a hot topic in the field of medical life sciences, as they are highly relevant in diagnostic applications. In this regard, a large variety of novel imaging methods for MNP in biological systems have been invented. In this proof-of-concept study, a new and novel technique is explored, called Magnetic Particle Mapping (MPM), using resonant magnetoelectric (ME) sensors for the detection of MNPs that could prove to be a cheap and efficient way to localize the magnetic nanoparticles.

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Hippocampal Dentate Gyrus Atrophy Predicts Pattern Separation Impairment in Patients with LGI1 Encephalitis.

Neuroscience

February 2019

Dept. of Neurology, Memory Disorders and Plasticity Group, University Hospital Schleswig-Holstein, University of Kiel, Arnold-Heller-Str. 3, 24105 Kiel, Germany. Electronic address:

Day-to-day life involves the perception of events that resemble one another. For the sufficient encoding and correct retrieval of similar information, the hippocampus provides two essential cognitive processes. Pattern separation refers to the differentiation of similar input information, whereas pattern completion reactivates memory representations based on noisy or degraded stimuli.

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Growth hormone deficiency (GHD) results in an impaired health-related quality of life (HrQoL) and cognitive impairment in the attention and memory domain. GHD is assumed to be a frequent finding after brain injury due to traumatic brain injury (TBI), aneurysmal subarachnoid hemorrhage (SAH) or ischemic stroke. Hence, we set out to investigate the effects of growth hormone (GH) replacement therapy in patients with isolated GHD after brain injury on HrQoL, cognition, and abdominal fat composition.

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Objectives: Real world implementation of proactive screening and brief intervention in health care is threatened by high cost. Using e-health interventions and screening for multiple health risk factors may provide more efficiency. We describe methodological details of a proactive multipurpose health risk screening in health care settings and report on participation rates, participants' characteristics, and participation factors.

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Despite sizeable short-term effects of neurofeedback (NF) therapy on attention-deficit and hyperactivity disorder (ADHD), longer-term clinical, comorbidity and self-regulation outcomes are less systematically studied. The aim of this largest NF follow-up to date was to evaluate these outcomes 6 months after NF compared to a semi-active control to disentangle specific from unspecific sustained effects. We performed a multicenter, randomized, parallel, controlled, clinical, superiority trial in five German university outpatient departments.

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Many primary care patients with high somatic symptom burden do not initiate mental health treatment. Using a cross-sectional design, this study aimed to identify predictors of psychotherapy seeking behavior for patients with high somatic symptom burden within the last 12 months. Data from 20 primary care practices were analyzed.

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The aim of this study was to compare chronotype- and age-dependent sleep disturbances and social jetlag between rotating shift workers and non-shift workers, and between different types of shifts. In the Klokwerk+ cohort study, we included 120 rotating shift workers and 74 non-shift workers who were recruited from six Dutch hospitals. Participants wore Actigraph GT3X accelerometers for 24 hr for 7 days.

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A salutogenic inquiry into positive aging - a longitudinal analysis.

Aging Ment Health

November 2019

Institute for Medical Psychology, University Medicine Greifswald, Greifswald , Germany.

Based on a gero-salutogenic approach, we investigated the stability of the sense of coherence over a time span of four years in active older individuals and long-term effects of this life orientation on three different indicators of positive aging-subjective well-being, psychological health and physical health. This is the first study to explore associations between gain in sense of coherence and future positive aging. Our longitudinal sample consisted of 125 physically active individuals (73.

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Brain-computer interfaces (BCIs) enable communication with others and allow machines or computers to be controlled in the absence of motor activity. Clinical studies evaluating neural prostheses in amyotrophic lateral sclerosis (ALS) patients have been performed; however, to date, no study has reported that ALS patients who progressed from locked-in syndrome (LIS), which has very limited voluntary movement, to a completely locked-in state (CLIS), characterized by complete loss of voluntary movements, were able to continue controlling neural prostheses. To clarify this, we used a BCI system to evaluate three late-stage ALS patients over 27 months.

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Background: To investigate (a) the diagnostic agreement between diagnoses of somatoform disorders, depressive and anxiety disorders obtained from a structured clinical interview and diagnoses reported from primary care physicians (PCPs) and (b) to identify patient and PCP-related predictors for the diagnostic agreement regarding the presence of a somatoform disorder.

Methods: Data from a cross-sectional study comprising 112 primary care patients at high risk for somatoform disorders were analyzed. Diagnoses according to International Classification of Diseases, 10th revision (ICD-10) for somatoform, depressive and anxiety disorders were obtained from the Composite International Diagnostic Interview (CIDI) and compared with the diagnoses of the patients' PCPs documented in their medical records.

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Variable training but not sleep improves consolidation of motor adaptation.

Sci Rep

October 2018

BioMotion Center, Institute of Sports and Sports Science, Karlsruhe Institute of Technology, 76131, Karlsruhe, Germany.

How motor memory consolidates still remains elusive. Consolidation of motor skills has been shown to depend on periods of sleep. Conversely, motor adaptation during tasks not dependent on the hippocampus may not depend on sleep.

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The non-transcranial TMS-evoked potential is an inherent source of ambiguity in TMS-EEG studies.

Neuroimage

January 2019

Danish Research Centre for Magnetic Resonance, Centre for Functional and Diagnostic Imaging and Research, Copenhagen University Hospital Hvidovre, Denmark; Department of Neurology, Copenhagen University Hospital Bispebjerg, Bispebjerg Bakke 23, 2400 København NV, Denmark. Electronic address:

Transcranial Magnetic Stimulation (TMS) excites populations of neurons in the stimulated cortex, and the resulting activation may spread to connected brain regions. The distributed cortical response can be recorded with electroencephalography (EEG). Since TMS also stimulates peripheral sensory and motor axons and generates a loud "click" sound, the TMS-evoked EEG potentials (TEPs) reflect not only neural activity induced by transcranial neuronal excitation but also neural activity due to somatosensory and auditory processing.

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Background: Exercise effects in cancer patients often appear modest, possibly because interventions rarely target patients most in need. This study investigated the moderator effects of baseline values on the exercise outcomes of fatigue, aerobic fitness, muscle strength, quality of life (QoL), and self-reported physical function (PF) in cancer patients during and post-treatment.

Methods: Individual patient data from 34 randomized exercise trials (n = 4519) were pooled.

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Article Synopsis
  • The study aimed to identify which cancer patients benefit most from different exercise interventions by analyzing various factors that influence exercise effectiveness.
  • Researchers conducted a meta-analysis of data from 28 randomized controlled trials that assessed the impact of exercise on muscle strength and aerobic fitness in cancer patients.
  • Findings revealed that exercise significantly enhances upper and lower body strength and aerobic fitness, with better results associated with supervised sessions, specific frequencies, and certain patient demographics like younger age and marital status.
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Background: Little is known about the impact of brief alcohol interventions on mental and general health. The aim was to investigate whether brief interventions for general hospital inpatients with at-risk drinking can improve mental and general health over 2 years; and whether effects are dependent on how they are delivered: in-person or through computer-generated feedback letters (CO).

Methods: Three-arm randomized controlled trial with 6-, 12-, 18-, and 24-month follow-ups.

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Short-term stability of different drinking patterns over the course of four weeks among adults. A latent transition analysis.

Drug Alcohol Depend

October 2018

Institute of Social Medicine and Prevention, University Medicine Greifswald, Walther-Rathenau-Str. 48, D-17475 Greifswald, Germany; German Centre for Cardiovascular Research, Partner Site Greifswald, Fleischmannstr. 42-44, D-17475 Greifswald, Germany; Institute and Policlinic for Occupational and Social Medicine, Medical Faculty, TU Dresden, Fetscherstr. 74, D-01307 Dresden, Germany. Electronic address:

Objective: The purpose of the present study was to identify drinking patterns and determine their intraindividual stability over the course of four weeks among a sample of adults from the general population.

Methods: The sample comprised 288 adults who reported drinking alcohol at least once per month (49% female; mean age = 33.1 years, SD = 12.

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Identification of neurophysiological biotypes in attention deficit hyperactivity disorder.

Psychiatry Clin Neurosci

November 2018

Psychophysiology and Optical Imaging, Department of Psychiatry and Psychotherapy, University of Tübingen, Tübingen, Germany.

Aim: Findings on neurophysiological alterations in attention deficit hyperactivity disorder (ADHD) have been proposed to underlie ADHD symptoms, with different etiological pathways for different patient biotypes. We aimed at determining whether neurophysiological deviations confirm distinct neurophysiological profiles in ADHD, thus providing direct evidence for the endophenotype concept.

Methods: Neurophysiological biotypes were investigated in 87 adult patients with ADHD using cluster analysis.

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Background: The population impact of alcohol screening and brief intervention might be increased by approaching an entire population rather than individuals at high risk only. The aim is to present the protocol of the study "Testing a proactive expert system intervention to prevent and to quit at-risk alcohol use" (PRINT) which tests the efficacy of a computer-based brief intervention (i) to elicit drinking reductions among persons with at-risk alcohol use and (ii) to prevent at-risk alcohol use among current low-risk drinkers.

Methods/design: The PRINT study is a two-arm randomized controlled trial with a 12-month follow-up.

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MAGIC: An open-source MATLAB toolbox for external control of transcranial magnetic stimulation devices.

Brain Stimul

May 2018

Department of Neurology & Stroke, and Hertie Institute for Clinical Brain Research, Eberhard Karls University of Tübingen, Hoppe-Seyler-Str. 3, 72076, Tübingen, Germany; Institute for Medical Psychology and Behavioral Neurobiology, Eberhard Karls University of Tübingen, Otfried-Müller-Straße 25, 72076, Tübingen, Germany.

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Measurement invariance of the alcohol use disorders identification test: Establishing its factor structure in different settings and across gender.

Drug Alcohol Depend

August 2018

(a)University Medicine Greifswald, Institute of Social Medicine and Prevention, Walther-Rathenau-Str. 48, D-17475 Greifswald, Germany; (b)German Center for Cardiovascular Research, Partner site Greifswald, Greifswald, Germany.

Introduction: The Alcohol Use Disorders Identification Test (AUDIT) is an internationally well-established screening tool for the assessment of hazardous and harmful alcohol consumption. To be valid for group comparisons, the AUDIT should measure the same latent construct with the same structure across groups. This is determined by measurement invariance.

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Sabel BA, Cárdenas-Morales L, Gao Y. Vision Restoration in Glaucoma by activating Residual Vision with a Holistic, Clinical Approach: A Review. J Curr Glaucoma Pract 2018;12(1):1-9.

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