Gender differences in Russian adolescent mental health from 1999 to 2021.

This study examined secular trends in Russian adolescent mental health, the specific effects of the COVID-19 pandemic, and associations with country-level indicators. A cross-sectional survey of 12,882 adolescents aged 11-18 years was carried out between 1999 and 2021 using the Strengths and Difficulties Questionnaire. The results showed an incline in girls' internalizing problems with a two-fold increase in the gender gap.

Epidemiology Helicobacter pylori infection in children in the Tyva Republic (Russia).

Background: Tyva Republic is a small mountainous area at the geographical center of Asia in southern Siberia, with a high incidence of gastric cancer.

Aim: We examined the prevalence of H. pylori and associated risk factors among children in Tyva.

[The prevalence and mental comorbidity of internet-dependent behavior in adolescents of Central Siberia].

Objective: To study the prevalence of Internet addiction (IA) in adolescents in Central Siberia and the association of IA with mental health problems.

Material And Methods: The study included 2950 adolescents (44.7% boys and 54.

[The activity of NAD- and NAD(P)-dependent dehydrogenases in lymphocytes of peripheral blood in Graves' disease].

Background: The regulatory effect of thyroid hormones on the metabolism of the immune system cells (activation of oxidative processes, separation of oxidative phosphorylation and increased protein synthesis) depends on their number. Changes in the activity of intracellular enzymes in Graves’ disease (GD) can determine the mechanisms of maintaining autoimmune inflammation in relapse of the disease. The exact role of NAD(P)-dependent dehydrogenases in the development and maintenance of immune response in GD is still poorly investigated.

[Health risk factors in the family-members of chlamydiosis patients].

Aim: To study the characteristics of health state in family-members of ENT-patients with identified Chlamydia infection.

Methods: We have examined 245 members of 87 families of otorhinolaryngological patients with verified (44 families) and without (44 families) Chlamydia infection. Laboratory methods of the research included the identification of the following types: Chlamydia trachomatis and Chlamydophila pneumoniae.

[European registry Helicobacter pylori (Hp-EuReg): how has clinical practice changed in Russia from 2013 to 2018 years].

Unlabelled: The multicenter prospective observational study initiated by the European Helicobacter and Microbiota Study Group (EHMSG) is conducted in 27 countries in Europe. The data from the Russian part of the European registry for the management of Helicobacter pylori infection (European Registry on the management of Helicobacter pylori infection, protocol: "Hp-EuReg") allows us to analyze the real clinical practice of diagnosis and treatment of H. pylori and compare it with international recommendations.

[Possible Genetic Predictors of Cardiovascular Complications After Coronary Artery Bypass Surgery].

Purpose: to investigate associations of single nucleotide polymorphisms (SNPs) rs2046934, rs1126643, rs5918, rs6065, rs4244285; rs4986893 with cardiovascular complications (CVC) in patients after CABG.

Materials And Methods: We enrolled in this study 130 patients with stable functional class II-IV angina. After CABG 69 patients received ASA (100 mg of enteric form), 61 patients received dual antiplatelet therapy (ASA 100 mg + clopidogrel 75 mg).

[Characteristic of the microbiocenosis of the nasal mucous membrane in the patients presenting with acute bacterial rhinosinusitis].

The objective of the present work was to study the specific features of the microbiocenosis of the nasal mucous membrane in the patients presenting with acute bacterial rhinosinusitis (ABRS). We examined 86 patients with this condition at the age varying from 18 to 64 years. The control group consisted of practically healthy blood donors (n=156) registered at the Krasnoyarsk Regional Blood Centre #1; they were matched to the patients of the main study group in terms of the age and sex.

[Changes in the content of catecholamines in blood lymphocytes after food consumption in young men in accordance with pronounced body fat component].

We examined practically healthy young men (81 in the ages from 17 to 21 years), the students living in the city of Krasnoyarsk, for whom we defined their somatotypes according to V.P. Chtetzov scheme (1978) and component content of the body (fat, muscle and bone) by caliperometry technique.

[European Registry on the management of Helicobacter pylori infection (Hp-EuReg protocol): The first results of Russian centers].

Aim: To assess the clinical practice of diagnosis and treatment in patients with Helicobacter pylori infection and to compare this practice with the international guidelines in the European Registry on the management of Helicobacter pylori infection, Hp-EuReg protocol), a multicenter prospective observational study initiated by the European Helicobacter and Microbiota Study Group. MATERIALs AND METHODS: The data of 813 patients infected with H. pylori and entered in the Hp-EuReg register by the Russian centers in 2013-2015 were analyzed.

[The frequency and clinical aspects of extraesophageal syndromes in elderly patients with gastroesophageal reflux disease].

Aim: To investigate the frequency of extraesophageal syndromes in elderly patients with gastroesophageal reflux disease (GERD).

Materials And Methods: This cross-sectional study was conducted to compare the clinical manifestations of GERD in 1100 patients aged 60 to 75 years and in 453 patients aged 36 to 60 years. A control group consisted of 154 elderly patients without GERD and 178 mature-aged patients without this condition.

[Borderline mental disorders in schoolchildren].

Objective: To study the frequency of borderline mental disorders in children of secondary general education schools.

Material And Methods: We examined 1013 male and female schoolchildren, aged 12-14 and 15-17 years. In the first stage, the they completed a screening questionnaire to estimate the presence of a range of psychosomatic syndromes.

The peculiarities of food allergies in accordance with the level of injury of respiratory tract in children of Eastern Siberia.

Aim: To determine the course of food allergy in accordance with the level of respiratory tract injury in children of Eastern Siberia.

Design Of The Research: We have examined 70 children aged 2-16 , who have food sensibilization. We divided them into 2 groups: group I (n = 32) with diseases of the upper and middle respiratory tract; and group II (n = 38) with diseases of the lower respiratory tract.

Immunological parameters and gene polymorphisms (C-590T IL4, C-597A IL10) in severe bronchial asthma in children from the Krasnoyarsk region, West Siberia.

Background: Bronchial asthma is a common disease caused by interplay between multiple determinants, including genetic and immune variations.

Objective: To investigate the main indices of humoral and cellular branches of immunity, features of cytokine regulation and cytokine genes in children with atopic bronchial asthma (BA) with different levels of disease control.

Design: Fifty children with controlled BA (CBA) and 50 with uncontrolled BA (UBA) were analyzed.

Lipid peroxidation in erythrocyte membranes of women with benign and malignant neoplasms of the endometrium.

The content of primary and secondary products of membrane peroxidation, total cholesterol concentration, and relative microviscosity of erythrocyte membranes were measured in women with endometrial cancer and uterine leiomyoma. The content of conjugated dienes in erythrocytes was highest in female patients with malignant tumors of the endometrium. The relative microviscosity of erythrocyte membranes in patients with uterine leiomyoma and endometrial cancer was elevated in the zone of lipid--lipid and protein--lipid contacts.

[The activity of NAD(P)-dependent dehydrogenases in blood lymphocytes in children and adolescents with different duration of insulin-dependent diabetes mellitus].

The levels of blood lymphocyte NAD(P)-dependent dehydrogenases were investigated in children and teenagers with different duration of insulin-dependent diabetes mellitus (IDDM). The level of some NAD(P)-dependent dehydrogenases changed proportionally in dependence of IDDM duration and insulin therapy did not restore their activities to the normal level. It is suggested that these changes may reflect decrease of energy metabolism and plastic processes in blood lymphocytes from diabetic children and teenagers reflecting.