550 results match your criteria: "Institute for Infocomm Research.[Affiliation]"

The explainability of Graph Neural Networks (GNNs) is critical to various GNN applications, yet it remains a significant challenge. A convincing explanation should be both necessary and sufficient simultaneously. However, existing GNN explaining approaches focus on only one of the two aspects, necessity or sufficiency, or a heuristic trade-off between the two.

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Purpose: Coronary CT angiography (CCTA) is well established for the diagnostic evaluation and prognostication of coronary artery disease (CAD). The growing burden of CAD in Asia and the emergence of novel CT-based risk markers highlight the need for an automated platform that integrates patient data with CCTA findings to provide tailored, accurate cardiovascular risk assessments. This study aims to develop an artificial intelligence (AI)-driven platform for CAD assessment using CCTA in Singapore's multiethnic population.

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Hybrid Window Decoding for Joint Source Channel Anytime Coding System.

Entropy (Basel)

November 2024

The School of Ocean Information Engineering, Jimei University, Xiamen 361021, China.

Joint source channel anytime coding (JSCAC) is a kind of joint source channel coding (JSCC) systems based on the causal spatially coupled coding and joint expanding window decoding (JEWD) techniques. JSCAC demonstrates greatly improved error correction performance, as well as higher decoding complexity. This work proposes a joint hybrid window decoding (JHWD) algorithm for JSCAC systems, aiming to reduce the decoding complexity while maintaining comparable error correction performance with the state of the art.

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DeepRSMA: a cross-fusion-based deep learning method for RNA-small molecule binding affinity prediction.

Bioinformatics

November 2024

Machine Intellection Department, Institute for Infocomm Research, Agency for Science, Technology and Research (A*STAR), Singapore 138632, Singapore.

Article Synopsis
  • - This study introduces DeepRSMA, a new deep learning method designed to predict RNA-small molecule affinity (RSMA), which is vital for developing RNA-targeted drugs for diseases.
  • - DeepRSMA utilizes advanced techniques like nucleotide-level and atomic-level feature extraction, as well as a Transformer-based cross-fusion module, to effectively analyze RNA and small molecules from different perspectives.
  • - The results indicate that DeepRSMA outperforms existing methods, providing insights that could assist in designing effective RNA-targeted therapies, with the code and data accessible for public use.
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Wearable EEG-Based Brain-Computer Interface for Stress Monitoring.

NeuroSci

December 2024

Institute for Infocomm Research, Agency for Science, Technology and Research (A*STAR), 1 Fusionopolis Way, #21-01 Connexis (South Tower), Singapore 138632, Singapore.

Detecting stress is important for improving human health and potential, because moderate levels of stress may motivate people towards better performance at cognitive tasks, while chronic stress exposure causes impaired performance and health risks. We propose a Brain-Computer Interface (BCI) system to detect stress in the context of high-pressure work environments. The BCI system includes an electroencephalogram (EEG) headband with dry electrodes and an electrocardiogram (ECG) chest belt.

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Article Synopsis
  • Telehealth interventions are important for aiding patients with chronic conditions like heart failure and type 2 diabetes by improving health outcomes through structured conversations about lifestyle management.
  • This study analyzed 729 telehealth calls made over a year to 50 heart failure patients, focusing specifically on lifestyle management topics and how these discussions related to their healthcare usage.
  • The research assessed the content and structure of lifestyle-focused calls compared to those not solely about lifestyle, while also evaluating the nurses’ perspectives on the effectiveness and follow-up needed for these calls, ultimately relating them to patient admissions in the healthcare system.
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Background: The comparison of coronary computed tomography angiography plaques and perivascular adipose tissue (PVAT) between patients with acute myocardial infarction (AMI) posttreatment and patients with stable coronary artery disease is poorly understood. Our objective was to evaluate the differences in coronary computed tomography angiography-quantified plaque and PVAT characteristics in patients post-AMI and identify signs of residual inflammation.

Methods And Results: We analyzed 205 patients (age, 59.

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Synthetic lethality (SL) is a gold mine of anticancer drug targets, exposing cancer-specific dependencies of cellular survival. To complement resource-intensive experimental screening, many machine learning methods for SL prediction have emerged recently. However, a comprehensive benchmarking is lacking.

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Analysis of Field Trial Results for Excavation-Activities Monitoring with φ-OTDR.

Sensors (Basel)

September 2024

ST Engineering Urban Solutions Ltd., 6 Ang Mo Kio Electronics Park Road, Singapore 567711, Singapore.

Underground telecommunication cables are highly susceptible to damage from excavation activities. Preventing accidental damage to underground telecommunication cables is critical and necessary. In this study, we present field trial results of monitoring excavation activities near underground fiber cables using an intensity-based phase-sensitive optical time-domain reflectometer (φ-OTDR).

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Pipeline Elbow Corrosion Simulation for Strain Monitoring with Fiber Bragg Gratings.

Micromachines (Basel)

August 2024

Institute for Infocomm Research (I2R), Agency for Science, Technology and Research (A⋆STAR), Singapore 138632, Singapore.

This study addresses the limitation of traditional non-destructive testing methods in real-time corrosion monitoring of pipe elbows by proposing the utilization of fiber Bragg grating (FBG) strain sensors, renowned for their resilience in harsh environments. However, the current mathematical relationship model for strain representation of elbow corrosion is still lacking. This paper develops a finite element model to scrutinize the strain changes in the elbow due to corrosion under hydrostatic pressure and bending loads.

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Pharmacotherapy guidelines for type 2 diabetes (T2D) emphasize patient-centered care, but applying this approach effectively in outpatient practice remains challenging. Data-driven treatment optimization approaches could enhance individualized T2D management, but current approaches cannot account for drug-specific and dose-dependent variations in safety and efficacy. We developed and evaluated an AI Drug mix and dose Advisor (AIDA) for glycemic management, using electronic medical records from 107,854 T2D patients in the SingHealth Diabetes Registry.

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Motivation: A key challenge in deep generative models for molecular design is to navigate random sampling of the vast molecular space, and produce promising molecules that strike a balance across multiple chemical criteria. Fragment-based drug design (FBDD), using fragments as starting points, is an effective way to constrain chemical space and improve generation of biologically active molecules. Furthermore, optimization approaches are often implemented with generative models to search through chemical space, and identify promising samples which satisfy specific properties.

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Motivation: Effective molecular representation is critical in drug development. The complex nature of molecules demands comprehensive multi-view representations, considering 1D, 2D, and 3D aspects, to capture diverse perspectives. Obtaining representations that encompass these varied structures is crucial for a holistic understanding of molecules in drug-related contexts.

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In medical image segmentation, it is often necessary to collect opinions from multiple experts to make the final decision. This clinical routine helps to mitigate individual bias. However, when data is annotated by multiple experts, standard deep learning models are often not applicable.

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Smart Sleep Monitoring: Sparse Sensor-Based Spatiotemporal CNN for Sleep Posture Detection.

Sensors (Basel)

July 2024

Department of Respiratory and Critical Care Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 1 Shuaifuyuan Wangfujing, Beijing 100730, China.

Sleep quality is heavily influenced by sleep posture, with research indicating that a supine posture can worsen obstructive sleep apnea (OSA) while lateral postures promote better sleep. For patients confined to beds, regular changes in posture are crucial to prevent the development of ulcers and bedsores. This study presents a novel sparse sensor-based spatiotemporal convolutional neural network (SCNN) for detecting sleep posture.

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Effective type label-based synergistic representation learning for biomedical event trigger detection.

BMC Bioinformatics

July 2024

Aural & Language Intelligence, Institute for Infocomm Research, Agency for Science, Technology and Research, 1 Fusionopolis Way, Singapore, Singapore.

Background: Detecting event triggers in biomedical texts, which contain domain knowledge and context-dependent terms, is more challenging than in general-domain texts. Most state-of-the-art models rely mainly on external resources such as linguistic tools and knowledge bases to improve system performance. However, they lack effective mechanisms to obtain semantic clues from label specification and sentence context.

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Privacy preservation for federated learning in health care.

Patterns (N Y)

July 2024

Center for Federated Learning in Medicine, Indiana University, Indianapolis, IN, USA.

Artificial intelligence (AI) shows potential to improve health care by leveraging data to build models that can inform clinical workflows. However, access to large quantities of diverse data is needed to develop robust generalizable models. Data sharing across institutions is not always feasible due to legal, security, and privacy concerns.

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Automated and accurate classification of pneumonia plays a crucial role in improving the performance of computer-aided diagnosis systems for chest X-ray images. Nevertheless, it is a challenging task due to the difficulty of learning the complex structure information of lung abnormality from chest X-ray images. In this paper, we propose a multi-view aggregation network with Transformer (TransMVAN) for pneumonia classification in chest X-ray images.

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Deformable Image registration is a fundamental yet vital task for preoperative planning, intraoperative information fusion, disease diagnosis and follow-ups. It solves the non-rigid deformation field to align an image pair. Latest approaches such as VoxelMorph and TransMorph compute features from a simple concatenation of moving and fixed images.

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In the last decade, scientists investigating human social cognition have started bringing traditional laboratory paradigms more "into the wild" to examine how socio-cognitive mechanisms of the human brain work in real-life settings. As this implies transferring 2D observational paradigms to 3D interactive environments, there is a risk of compromising experimental control. In this context, we propose a methodological approach which uses humanoid robots as proxies of social interaction partners and embeds them in experimental protocols that adapt classical paradigms of cognitive psychology to interactive scenarios.

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Choroidal Layer Analysis in OCT images via Ambiguous Boundary-aware Attention.

Comput Biol Med

June 2024

Laboratory of Advanced Theranostic Materials and Technology, Ningbo Institute of Materials Technology and Engineering, Chinese Academy of Sciences, Ningbo, China. Electronic address:

Optical Coherence Tomography (OCT) is a commonly used retina imaging technique, and it is capable of revealing the morphology of the choroid. However, the segmentation and quantitative analysis of the sublayers and vessels in choroid are rarely explored, primarily due to the indistinct boundaries of choroidal sublayers, and imbalanced distribution of vessels observed in OCT imagery. In this paper, we propose a novel two-stage architecture called Choroidal Layer Analysis network (CLA), that may be considered the first attempt in this research community for joint segmentation of choroidal sublayers and choroidal vessels in OCT images.

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Review of EEG Affective Recognition with a Neuroscience Perspective.

Brain Sci

April 2024

Institute for Infocomm Research, Agency for Science, Technology and Research, A*STAR, 1 Fusionopolis Way, #21-01 Connexis, Singapore 138632, Singapore.

Emotions are a series of subconscious, fleeting, and sometimes elusive manifestations of the human innate system. They play crucial roles in everyday life-influencing the way we evaluate ourselves, our surroundings, and how we interact with our world. To date, there has been an abundance of research on the domains of neuroscience and affective computing, with experimental evidence and neural network models, respectively, to elucidate the neural circuitry involved in and neural correlates for emotion recognition.

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Batteries play a crucial role as energy storage devices across various industries. However, achieving high performance often comes at the cost of safety. Continuous monitoring is essential to ensure the safety and reliability of batteries.

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Eye movement analysis is critical to studying human brain phenomena such as perception, cognition, and behavior. However, under uncontrolled real-world settings, the recorded gaze coordinates (commonly used to track eye movements) are typically noisy and make it difficult to track change in the state of each phenomenon precisely, primarily because the expected change is usually a slower transient process. This paper proposes an approach, Improved Naive Segmented linear regression (INSLR), which approximates the gaze coordinates with a piecewise linear function (PLF) referred to as a hypothesis.

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Polar Decomposition of Jones Matrix and Mueller Matrix of Coherent Rayleigh Backscattering in Single-Mode Fibers.

Sensors (Basel)

March 2024

Institute for Infocomm Research (I2R), Agency for Science, Technology and Research (A*STAR), 1 Fusionopolis Way, #21-01, Connexis South Tower, Singapore 138632, Singapore.

The Jones matrix and the Mueller matrix of the coherent Rayleigh backscattering (RB) in single-mode fibers (SMFs) have been derived recently. It has been shown that both matrices depict two polarization effects-birefringence and polarization-dependent loss (PDL)-although the SMF under investigation is purely birefringent, having no PDL. In this paper, we aim to perform a theoretical analysis of both matrices using polar decomposition.

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