Predictive modeling of nitrogen and phosphorus concentrations in rivers using a machine learning framework: A case study in an urban-rural transitional area in Wenzhou China.

Rapid urbanization in China since 1980 generated environmental pressures of non-point source pollution (NPSP) and increased wide public concerns. Excessive quantities of nitrogen (N) and phosphorus (P) is a significant source of aquatic pollution, despite of their roles as essential nutritional elements for aquatic life processes. In this study, we present a new framework using random forest (RF) as a powerful machine learning algorithm driven by geo-datasets to estimate and map the concentration of total nitrogen (TN) and phosphorus (TP) at a spatial resolution for the Wen-Rui Tang River (WRTR) watershed, which is a typically urban-rural transitional area in east coastal region of China.

Organophosphorus flame retardants and their metabolites in paired human blood and urine.

Organophosphorus flame retardants (OPFRs) have been shown to be carcinogenic, neurotoxic, and endocrine disruptive, so it is important to understand the levels of OPFRs in human body as well as the modes of external exposure. In this study, we investigated the levels of 13 OPFRs and 7 phosphodiester metabolites in paired human blood and urine, as well as the influencing factors (region, age and gender), and studied the relationship between OPFRs and oxidative stress by urinary metabolites. We found that the concentrations of triphenyl phosphate (TPhP) and tris-(2-ethylhexyl) phosphate (TEHP) in the blood of urban populations were higher than those of rural populations, and that younger populations suffered higher TPhP and 2-ethylhexyl diphenyl phosphate (EHDPP) exposures than older populations.

Associations of screen use with physical activity and social capital amid the COVID-19 pandemic: A network analysis of youths in China.

Inconsistent correlations of screen use with physical activity (PA) and social capital (SC) in youths have been observed in existing cross-sectional studies. This study aimed to elucidate associations among variables in screen use, PA, and SC domains during COVID-19, to improve the prediction and prevention of suboptimal health status in youths. An online survey based on the nationwide COVID-19 Impact on Lifestyle Change Survey (COINLICS) was conducted in China, and 10,082 youths reported their screen use, PA, and SC in the months immediately before, during, and after the COVID-19 lockdown.

Development and validation of an age-sex-ethnicity-specific metabolic syndrome score in the Chinese adults.

Metabolic syndrome (MetS) is characterized by metabolic dysfunctions and could predict future risk for cardiovascular diseases (CVDs). However, the traditionally defined dichotomous MetS neither reflected MetS severity nor considered demographic variations. Here we develop a continuous, age-sex-ethnicity-specific MetS score based on continuous measures of the five metabolic dysfunctions (waist circumference [WC], triglycerides [TG], high-density lipoprotein cholesterol [HDL-C], mean arterial pressure [MAP], and fasting blood glucose [FBG]).

The impact of ambient air pollution on hospital admissions, length of stay and hospital costs for patients with diabetes mellitus and comorbid respiratory diseases in Panzhihua, Southwest China.

Background: There is limited evidence on association between air pollutants and hospital admissions, hospital cost and length of stay (LOS) among patients with diabetes mellitus (DM) and comorbid respiratory diseases (RD), especially in low- and middle-income countries (LMICs) with low levels of air pollution.

Methods: Daily data on RD-DM patients were collected in Panzhihua from 2016 to 2020. A generalised additive model (GAM) was used to explore the effect of air pollutants on daily hospital admissions, LOS and hospital cost.

Association between perceived noise at work and mental health among employed adults in Southwest China.

Background: Perceived noise at work may contribute more to worsening mental health than objectively measured noise. However, evidence regarding this association is scarce. We investigated the associations of perceived noise at work with anxiety and depression and identified vulnerable subpopulations.

Influences of long-term care insurance on pulmonary and urinary tract infections among older people with disability.

Background: Pulmonary infection (PI) and urinary tract infection (UTI) have been the most common cause of hospitalization and most frequent infection respectively in older people with disability (OPWD). Long-term care insurance (LTCI) policy, intending to provide services to reduce the disease burden of OPWD, it remains unclear whether LTCI could reduce PI-, and UTI-related hospitalizations. This quasi-experimental study aimed to assess the influences of LTCI on all-cause, especially PI- and UTI-related hospitalizations among OPWD and the variation across sociodemographic characteristics.

Cardiac-to-adipose axis in metabolic homeostasis and diseases: special instructions from the heart.

Adipose tissue is essential for maintaining systemic metabolic homeostasis through traditional metabolic regulation, endocrine crosstalk, and extracellular vesicle production. Adipose dysfunction is a risk factor for cardiovascular diseases. The heart is a traditional pump organ.

Associations between long-term exposure to PM chemical constituents and allergic diseases: evidence from a large cohort study in China.

Background: Exposure to air pollutants may cause immune responses and further allergic diseases, but existing studies have mostly, if not all, focused on effects of short-term exposure to PM on allergic diseases.

Objectives: We estimated associations of long-term exposure to PM chemical constituents with allergic disease risks and effect modification.

Methods: We used the baseline of a newly established, provincially representative cohort of 51,480 participants in southwest China.

The relationship between family diet consumption, family environment, parent anxiety and nutrition status children during the COVID-19 pandemic: a longitudinal study.

Background: The COVID-19 pandemic has exacerbated the trends of childhood overweight, obesity, and malnutrition, as well as increased psychological stress and family conflicts among family members. It is important to explore the relationship between changes in the family environment during the COVID-19 on child nutrition.

Objective: This study aims to analyze the nutritional status of Chinese children during the COVID-19 pandemic and its relationship with family diet, family environment, and parental anxiety, in order to provide evidence for further interventions in children's nutritional status.

Long-term exposure to ambient PM constituents is associated with dyslipidemia in Chinese adults.

Background: Ambient particulate matter with aerodynamic diameter ≤ 2.5 µm (PM) consists of various toxic constituents. However, the health effect of PM may differ depending on its constituents, but the joint effect of PM constituents remains incompletely understood.

Occupational burnout, flourishing and job satisfaction among HIV/AIDS healthcare workers in Western China: a network analysis.

Background: Healthcare workers suffered with high prevalence of occupational burnout, which might be related with their job satisfaction and well-being. This study aimed to provide evidence of complex interrelations among occupational burnout, flourishing, and job satisfaction, and identify key variables from the perspective of network structure among healthcare workers.

Methods: A cross-sectional study was conducted between July and October 2021, and 907 (the response rate was 98.

Understanding early experiences of Chinese frontline nurses during the COVID-19 pandemic: A text mining and thematic analysis of social media information.

This study aims to explore the early experiences of frontline nurses at the beginning of the COVID-19 pandemic in China as expressed through social media posts. This study used an explanatory sequential mixed-method design. Text mining was used for sentiment analysis.

Public health priorities for Sino-Africa cooperation in Eastern Africa in context of flooding and malaria burden in Children: a tridecadal retrospective analysis.

Background: Malaria remains a major public health burden to children under five, especially in Eastern Africa (E.A), -a region that is also witnessing the increasing occurrence of floods and extreme climate change. The present study, therefore, explored the trends in floods, as well as the association of their occurrence and duration with the malaria incidence in children < 5 years in five E.

Toward a Prognostic Model for Mortality Risk in Older People Living With HIV: A Prospective Cohort Study From Southwestern China.

Objective: The existing prognostic models for mortality risk in people living with HIV (PLWH) may not be applicable for older PLWH because the risk factors were confined to biomarkers and clinical variables. We developed and validated a nomogram for the prognosis of all-cause mortality in older PLWH based on comprehensive predictors.

Design: Prospective cohort study.

Theoretical and Experimental Study on the Impact of Long-Wave Radiation on the Greenhouse Effect of a Prefabricated Temporary House.

In this paper, an experimental rig of a prefabricated temporary house (PTH) was first established. Then, predicted models for the thermal environment of the PTH with and without considering long-wave radiation were developed. Next, the exterior-surface, interior-surface and indoor temperatures of the PTH were calculated by using the predicted models.

Ultra-small superparamagnetic iron oxide nanoparticles for intra-articular targeting of cartilage in early osteoarthritis.

Early diagnosis of osteoarthritis (OA) is critical for effective cartilage repair. However, lack of blood vessels in articular cartilage poses a barrier to contrast agent delivery and subsequent diagnostic imaging. To address this challenge, we proposed to develop ultra-small superparamagnetic iron oxide nanoparticles (SPIONs, 4 nm) that can penetrate into the matrix of articular cartilage, and further modified with the peptide ligand WYRGRL (particle size, 5.

Advances in Enhancing Hemocompatibility of Hemodialysis Hollow-Fiber Membranes.

Hemodialysis, the most common modality of renal replacement therapy, is critically required to remove uremic toxins from the blood of patients with end-stage kidney disease. However, the chronic inflammation, oxidative stress as well as thrombosis induced by the long-term contact of hemoincompatible hollow-fiber membranes (HFMs) contribute to the increase in cardiovascular diseases and mortality in this patient population. This review first retrospectively analyzes the current clinical and laboratory research progress in improving the hemocompatibility of HFMs.

Experimental study on moisture and heat migration and deformation properties of unsaturated soil column under a temperature gradient during rainfall infiltration.

Mountainous areas in southwest China are rainy in summer. The rainfall infiltration process involves complex soil thermal-hydraulic-mechanical (THM) coupling problems. The researches on soil THM coupling are mostly focused on numerical simulations, whereas the corresponding model tests are relatively few, and the existing model test studies often ignore the effect of temperature gradients in the soil.

Detecting the Unseen: Understanding the Mechanisms and Working Principles of Earthquake Sensors.

The application of movement-detection sensors is crucial for understanding surface movement and tectonic activities. The development of modern sensors has been instrumental in earthquake monitoring, prediction, early warning, emergency commanding and communication, search and rescue, and life detection. There are numerous sensors currently being utilized in earthquake engineering and science.