Enhancing sidewalk accessibility assessment for wheelchair users: An adaptive weighting fuzzy-based approach.

To reach a destination within the community, it is crucial that wheelchair users possess the ability to plan, execute, and acquire knowledge of routes in a safe and efficient manner. While numerous methods have been introduced for assessing the accessibility of sidewalks, existing studies often overlook the variations in the perception of the accessibility of long segments based on each wheelchair user's capabilities. Extended distances may lead to increased fatigue, impacting the ability of individuals with mobility disabilities to navigate sidewalks comfortably and independently.

High fructose levels inhibit the proliferation of cardiomyocytes via the Notch1 signaling pathway.

Fructose, as a natural and simple sugar, is not significantly harmful to the human body when consumed in moderation and can provide energy for the body. High-fructose diets have been linked to an increased risk of a range of metabolic disorders, including hypertriglyceridemia, hypertension, and diabetes mellitus. These conditions are known to be associated with an elevated risk of developing cardiometabolic diseases.

An African perspective to biodiversity conservation in the twenty-first century.

Africa boasts high biodiversity while also being home to some of the largest and fastest-growing human populations. Although the current environmental footprint of Africa is low compared to other continents, the population of Africa is estimated at around 1.5 billion inhabitants, representing nearly 18% of the world's total population.

Unravelling the complexity of the relationship between social support sources and loneliness: A mixed-methods study with older adults.

Loneliness is an increasingly significant social and public health issue in contemporary societies. The available evidence suggests that social support is one of the key psychosocial processes for the reduction and prevention of loneliness. This study investigated the role played by sources of social support in the experience of social and emotional loneliness, identifying seven sources of support split between family (spouse/partner, children, grandchildren, siblings) and non-family (friends, neighbours).

The Role of Law Enforcement Mechanisms in the Care of Occupational Health and Safety in the Workplace of Health Professionals in Kosovo.

Background: Workplace health and safety are critical concerns for healthcare professionals, who are often exposed to various occupational hazards.

Objective: The aim of the study was to analyze the effectiveness and impact of law enforcement mechanisms in ensuring occupational health and safety for healthcare professionals in Kosovo.

Methods: Consist in conduct research on the role of law enforcement mechanisms in ensuring the occupational health and safety of healthcare professionals in Kosovo, using a qualitative methodology with questionnaires targeting the Health Inspectorate and Labor Inspectorate.

Provincial distribution of unintended pregnancy and its associated factors in Sierra Leone.

Background: Unintended pregnancy is a significant public health concern in Sierra Leone, with far-reaching consequences for both mothers and children. This issue impacts individual well-being, strains healthcare systems, and hinders socioeconomic development. This study examined the prevalence and factors associated with unintended pregnancy in Sierra Leone.

Unveiling the neglected role of the intensity of acute stress disorder in the prediction of full- and sub-threshold posttraumatic stress disorder: looking beyond the diagnosis.

Purpose: Exposure to traumatic events may lead to the development of Acute Stress Disorder (ASD) within the first month post-trauma in some individuals, while others may not exhibit ASD symptoms. ASD was introduced as a potential early indicator to identify those at higher risk of developing Posttraumatic Stress Disorder (PTSD), however, PTSD can occur in some individuals even without prior ASD. Assessing ASD post-trauma can assist in identifying those who would most benefit from intervention to prevent later PTSD, yet the predictive power of ASD varies across studies, with intensity of ASD symptoms and subthreshold PTSD often less considered.

Determining an optimal case definition using mid-upper arm circumference with or without weight for age to identify childhood wasting in the Philippines.

In resource-limited areas, where accurate weight-for-height Z-scores are hard to obtain, Mid-Upper Arm Circumference (MUAC) is a simple tool to identify wasted children. MUAC alone, however, may miss identification of many wasted children, leading to untimely intervention and potentially death. Our study aimed to identify the best-performing case definition to detect wasting by Weight-for-Height z-scores (WHZ) in Filipino children aged 6-59 months.

The Trend of Tuberculosis Case Notification Rates from 1995 to 2022 by Country Income and World Health Organization Region.

Over the past 27 years, three major global TB control strategies have been implemented, and it is important at this stage to evaluate their impact on tuberculosis (TB) case notification rates (CNRs). This study, therefore, analyzed TB CNR trends from 1995 to 2022 across 208 countries and islands, using data from the WHO Global TB Programme database. Countries were classified by income level and population size based on World Bank criteria.

Challenges of Occupational Health and Safety Management in Healthcare Institutions in Kosovo.

Background: Occupational health and safety (OHS) in healthcare institutions are crucial for the well-being of healthcare workers who are exposed to numerous risks in their working environment. In Kosovo, where healthcare institutions operate under resource constraints, understanding the challenges of OHS management challenges is vital for developing effective strategies.

Objective: This study aims to explore the challenges of OHS management in Kosovo's healthcare system, focusing on three levels of healthcare provision in both the public and private sectors.

Use of a fractional dose of inactivated polio vaccine (fIPV) to increase IPV coverage among children under 5 years of age in Somalia.

Background: Global efforts reduced incidence of polio cases from 350,000 in 1988 to 22 cases in 2022 globally. There have been no wild poliovirus (WPV) cases seen in Somalia since August 2014. However, in 2017, there was a surge in the number of cases of circulating vaccine-derived poliovirus type 2 (cVDPV2), even with different intervention responses using monovalent oral polio vaccine type 2 (mOPV2).

War Exposure and DNA Methylation in Syrian Refugee Children and Adolescents.

Importance: Exposure to war is associated with poor mental health outcomes. Adverse and traumatic experiences can lead to long-lasting DNA methylation changes, potentially mediating the link between adversity and mental health. To date, limited studies have investigated the impact of war on DNA methylation in children or adolescents, hampering our understanding of the biological impact of war exposure.

A fully automated social interaction chamber for studying social threat learning in mice.

Social interactions are fundamental for our survival as a predominately social species. We need and seek positive social interactions to navigate the world. However, when social interactions are negative, and occur in the presence of an aversive event, learning occurs to associate such social interactions as threatening.

Evidence of Zika virus circulation in human and livestock in Chad.

Zika virus (ZIKV) is a major public health problem worldwide. After several reported outbreaks, the current extent of infections caused by this orthoflavivirus in the Sahel remains to be explored. We investigated the prevalence of neutralizing antibodies against ZIKV in the general population, in HIV-infected individuals and in livestock in Chad using a seroneutralization assay that ensures high specificity level.

Regional distribution and factors associated with early marriage in Ghana: a cross-sectional study.

Background: Early marriage, the formal or informal union before age 18, remains a critical challenge in several low-and middle-income countries. It has adverse health and education-related implications on child brides. This study examined the regional distribution of early marriage and its associated factors in Ghana.

An analysis of demographic, socio-economic and clinical variables for mental illness and mental illness relapse in south-east nigeria.

Mental health has come into the front burner of development challenges amid declining socio-economic outcomes, especially in developing countries. Insecurity, conflicts and extremely threatening events, which trigger mental disorders, are common in South-East Nigeria, with many military operations, unknown gunmen attacks and kidnapping leading to the cold-blood assassination and kidnap of dear ones. The study aimed to analyze the demographic, socio-economic and clinical variables for mental illness in South-East Nigeria.

Father-separation and well-being in forcibly displaced Syrian children.

Forcibly displaced children often face separation from their parents, particularly fathers. These children endure the hardships of war, displacement, and the loss of a key attachment figure. Despite the critical role of attachment in children's well-being during periods of heightened stress, the impact of separation due to war and displacement has received little attention in empirical work.

Protocol for an open-source system to integrate calcium imaging, pupillometry, and locomotion-estimated tracking in head-fixed mice.

A wide selection of behavioral assays in systems neuroscience relies on head-fixation protocols to integrate in vivo multi-photon imaging approaches. For this, simultaneous pupillometry and locomotion tracking in head-fixed mice are used to measure behavioral responses and identify neural correlates. Here, we present an open-source protocol for assembling a complete head-fixation system that integrates pupillometry and locomotion-estimated tracking with multi-photon calcium imaging.

The Association of Cognitive Impairment and Depression with Malnutrition among Vulnerable, Community-Dwelling Older Adults: A Large Cross-Sectional Study.

(1) Background: Mental health issues in older adults, particularly cognitive impairment and depression, can affect nutritional status. This study investigates the prevalence of malnutrition among community-dwelling older adults at risk of social exclusion and dependency in Lebanon and its association with cognitive impairment and depression. (2) Methods: This cross-sectional study used secondary data from the TEC-MED project, involving 1410 older adults aged 60 and above in Beirut.