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"Seborrheic keratoses" that contain human papillomavirus are condylomata acuminata.

Am J Dermatopathol

August 1994

Institute for Dermatopathology, Jefferson Medical College, Philadelphia, Pennsylvania 19107.

Seborrheic keratoses situated in the anogenital region often resemble condylomata acuminata, clinically and histopathologically, yet they are benign neoplasms of unknown cause, in contrast to condylomata acuminata, which are hyperplasias induced by human papillomavirus (HPV). In the past few years, some authors claimed to have demonstrated HPV in some anogenital seborrheic keratoses, but they failed to set forth precise histopathologic criteria for diagnosis of seborrheic keratoses. Standards by which to diagnose condylomata acuminata histopathologically also are wanting in many textbooks of dermatology, general pathology, and dermatopathology.

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