Limitations of glycated albumin standardization when applied to the assessment of diabetes patients.

Objectives: Glycated albumin (GA) has potential value in the management of people with diabetes; however, to draw meaningful conclusions between clinical studies it is important that the GA values are comparable. This study investigates the standardization of the Norudia Glycated Albumin and Lucica Glycated Albumin-L methods.

Methods: The manufacturer reported imprecision was verified by performing CLSI-EP15-A3 protocol using manufacturer produced controls.

Evaluating the prognostic performance of a polygenic risk score for breast cancer risk stratification.

Background: Polygenic risk scores (PRS) could potentially improve breast cancer screening recommendations. Before a PRS can be considered for implementation, it needs rigorous evaluation, using performance measures that can inform about its future clinical value.

Objectives: To evaluate the prognostic performance of a regression model with a previously developed, prevalence-based PRS and age as predictors for breast cancer incidence in women from the Estonian biobank (EstBB) cohort; to compare it to the performance of a model including age only.

Distribution of Injectate and Sensory-Motor Blockade After Adductor Canal Block.

Background: The analgesic efficacy reported for the adductor canal block may be related to the spread of local anesthetic outside the adductor canal.

Methods: Fifteen patients undergoing knee surgery received ultrasound-guided injections of local anesthetic at the level of the adductor hiatus. Sensory-motor block and spread of contrast solution were assessed.

Neurotoxicity of perineural vs intraneural-extrafascicular injection of liposomal bupivacaine in the porcine model of sciatic nerve block.

Liposomal bupivacaine is a prolonged-release local anaesthetic, the neurotoxicity of which has not yet been determined. We used quantitative histomorphometric and immunohistochemical analyses to evaluate the neurotoxic effect of liposomal bupivacaine after perineural and intraneural (extrafascicular) injection of the sciatic nerve in pigs. In this double-blind prospective randomised trial, 4 ml liposomal bupivacaine 1.

The influence of staff-patient interactions on adherence behaviours.

The research assessed the influence of staff-patient interactions on adherence to a dietary regimen in dialysis patients. A random sample of 147 subjects provided data on clinical, psychosocial, and demographic measures. Results indicated that staff-patient interactions determine and predict adherence behaviours.

Language! Effects of an individualized structured language curriculum for middle and high school students.

This chapter documents the success of a 12-month individualized structured language curriculum (LANGUAGE!) provided to middle and high school juvenile offenders (n=45; 43 males; 2 females) enrolled in a rehabilitation program. Although individual students participated in the program for an average of just 22.7 weeks (SD 8.