Comparison of the Nutritional Composition of Meat Products Derived from Croatian Indigenous Pig Breeds.

There is a growing interest in the preservation of indigenous pig breeds, as they serve as a valuable genetic reserve. Pork meat products are widely consumed due to their desirable flavor, which is largely influenced by their chemical composition and the production processes employed. The aim of this study was to characterize and compare the nutritional composition, mineral content, and fatty acid profile of meat products derived from indigenous Croatian pig breeds.

Is Hemopexin a Nephrotoxin or a Marker of Kidney Injury in Renal Ischemia-Reperfusion?

Destabilization of heme proteins is recognized to play a role in acute kidney injury (AKI). Hemopexin (Hpx), known for its role in binding heme, mitigates free heme toxicity. Despite this, the potential adverse effects of Hpx deposition in kidney tissues and its impact on kidney function are not fully understood.

Proteomic Analysis of the Fish Pathogen Strain Vo-LM-18 and Its Outer Membrane Vesicles.

is the causative agent of atypical vibriosis in salmonids cultured in Chile. While extensive research provides insights into through phenotypic, antigenic, and genetic typing, as well as various virulence mechanisms, proteomic characterization remains largely unexplored. This study aimed to advance the proteomic knowledge of Chilean Vo-LM-18 and its OMVs, which have known virulence.

Advanced micropollutant and phosphorus removal with superfine powdered activated carbon and pile cloth media filtration.

Organic micropollutants (OMP) are ubiquitous in aquatic ecosystems and have a proven negative impact on the environment and drinking water resources. To remove OMP from municipal wastewater, the use of superfine Powdered Activated Carbon (sPAC) (d = 1.0 µm) compared to Powdered Activated Carbon (PAC) (d = 30.

Low-molecular weight organic acids can enhance the microbial reduction of iron oxide nanoparticles and pollutants by improving electrons transfer.

The combined application of dissimilatory iron-reducing bacteria (DIRB) and Fe(III) nanoparticles has garnered widespread interest in the contaminants transformation and removal. The efficiency of this composite system relies on the extracellular electron transfer (EET) process between DIRB and Fe(III) nanoparticles. While modifications to Fe(III) nanoparticles have demonstrated improvements in EET, enhancing DIRB activity also shows potential for further EET enhancement, meriting further investigation.

Bergapten Ameliorates Renal Fibrosis by Inhibiting Ferroptosis.

Renal fibrosis is the most common pathway for the development of end-stage renal disease (ESRD) in various kidney diseases. Currently, the treatment options for renal fibrosis are limited. Ferroptosis is iron-mediated lipid peroxidation, triggered mainly by iron deposition and ROS generation.

Loading of CAR-T cells with magnetic nanoparticles for controlled targeting suppresses inflammatory cytokine release and switches tumor cell death mechanism.

Therapies against hematological malignancies using chimeric antigen receptors (CAR)-T cells have shown great potential; however, therapeutic success in solid tumors has been constrained due to limited tumor trafficking and infiltration, as well as the scarcity of cancer-specific solid tumor antigens. Therefore, the enrichment of tumor-antigen specific CAR-T cells in the desired region is critical for improving therapy efficacy and reducing systemic on-target/off-tumor side effects. Here, we functionalized human CAR-T cells with superparamagnetic iron oxide nanoparticles (SPIONs), making them magnetically controllable for site-directed targeting.

Digital Monitoring of Anemia Control Measures in a District Using Anemia Mukt Bharat Health Management Information System Indicators.

Introduction: Anemia is a severe public health problem in India, affecting more than 50% of individuals across most age groups. The Anemia Mukt Bharat (AMB) program, with a target of a three-percentage point reduction in anemia prevalence per year, developed a monitoring mechanism based on a set of 18 indicators and six key performance indicators (KPIs) derived from routine reporting in the Health Management Information System (HMIS). The study's objective was to assess the status of anemia control measures in the district of Faridabad, Haryana, India, using AMB HMIS indicators from April 2018 to March 2019.

Ferrocene Catalyzed Radical Cascade Cyclization of Aryl 1,6-Diynes: Access to Cyanoalkylsulfonyl Fluorenes.

A ferrocene-catalyzed cyanoalkylsulfonylative radical cascade cyclization of aryl 1,6-diynes using cycloketone oxime esters and DABCO.(SO₂)₂ (DABSO) is reported. The reaction proceeds with notable chemo- and regioselectivity, without requiring additional oxidants or reductants.

An approach to Hemequity: Identifying the barriers and facilitators of iron deficiency reduction strategies in low- to middle-income countries.

Approximately 1.92 billion people worldwide are anaemic, and iron deficiency is the most common cause. Iron deficiency anaemia (IDA) disproportionately affects women of reproductive age and remains under-addressed in low- to middle-income countries (LMICs).

Ferric carboxymaltose for anemia in late pregnancy: a randomized controlled trial.

Over 46% of African pregnant women are anemic. Oral iron is recommended but often suboptimal, particularly late in pregnancy. Intravenous ferric carboxymaltose (FCM) could treat anemia in women in the third trimester in sub-Saharan Africa.

Iron Regulatory Protein 2 (IRP2) Deficiency Is Protective Against Resistive Breathing-induced Pulmonary Inflammation.

Iron regulatory protein 2 (IRP2), a post-transcriptional regulator of cellular iron metabolism has been associated with susceptibility to chronic obstructive pulmonary disease (COPD). Resistive breathing (RB) is the hallmark of the pathophysiology of obstructive airway diseases, especially during exacerbations, where increased mechanical stress is imposed on the lung. We have previously shown that RB, through tracheal banding, mimicking severe airway obstruction, induces pulmonary inflammation and injury in previously healthy mice.

Modeling Hydrogen Markets: Energy System Model Development Status and Decarbonization Scenario Results.

Hydrogen can be used as an energy carrier and chemical feedstock to reduce greenhouse gas emissions, especially in difficult-to-decarbonize markets such as medium- and heavy-duty vehicles, aviation and maritime, iron and steel, and the production of fuels and chemicals. Significant literature has been accumulated on engineering-based assessments of various hydrogen technologies, and real-world projects are validating technology performance at larger scales and for low-carbon supply chains. While energy system models continue to be updated to track this progress, many are currently limited in their representation of hydrogen, and as a group they tend to generate highly variable results under decarbonization constraints.

Effect of low temperature calcination on micro structure of hematite nanoparticles synthesized from waste iron source.

Hematite (α-FeO) nanoparticles have been synthesized from waste source of iron which contains a prominent amount of iron (93.2 %) and investigated the effect of low temperature calcination. The two-step synthesis method involved preparing ferrous sulfate through acid leaching process followed by oxidation and calcination at temperatures ranging from 200 to 400 °C to produce the desired α-FeO in nano form.

Hydrogen storage properties of TiFe-based composite with Ni addition.

This paper presents the preparation of the parental experimental alloy, featuring a standard composition of TiYZrFeNiMn, via the vacuum induction melting technique. Subsequently, the TiYZrFeNiMn alloy, with an addition of 2 wt% Ni, underwent mechanical ball milling to yield a TiFe-based composite for experimental purposes. The results of the experimental tests indicate that the composite alloy's phase composition comprises the TiFe primary phase, with a minor quantity of ZrMn phase segregated on the surface of the primary TiFe phase, as well as Ni phase.

Green synthesis of low-cost graphene oxide-nano zerovalent iron composite from solid waste for photocatalytic removal of antibiotics.

This study develops a graphene oxide-nano zerovalent iron (GO-nZVI) composite for the efficient removal of tetracycline and ciprofloxacin from water. The composite was synthesized using sugarcane bagasse as the matrix for graphene oxide (GO) and Sal leaf extract to reduce iron into nano zerovalent iron (nZVI). Microscopic analysis confirmed multiple GO layers with nZVI particles on their surface, while XRD and Raman spectroscopy verified the crystalline nature of the composite.

Hydration and carbonation curing of high ferrite clinker (FePC) synthesized using EAF slag.

Unlabelled: This study explores the use of Electric Arc Furnace (EAF) slag as a sustainable alternative raw material in cement clinker production. The research demonstrates the synthesis of ferrite-rich clinker using EAF slag, achieving a clinker composition of 47% alite, 32% ferrite, and 20% belite while replacing 20% of clinker raw materials i.e.

Factors Associated with Low Back Overuse Injuries in Sports Science Students - A Prospective Study.

Background: Sports science students (SPS) are more likely to be affected by low back pain (LBP) compared to the young, physically active population. The aim of this prospective study was to evaluate potential risk factors for LBP in the population of SPS.

Methods: Before the beginning of the study the participants (n=54) performed initial physical performance testing and gave blood samples.

Reconceptualizing Endothelial-to-mesenchymal transition in atherosclerosis: Signaling pathways and prospective targeting strategies.

Background: The modification of endothelial cells (ECs) biological function under pathogenic conditions leads to the expression of mesenchymal stromal cells (MSCs) markers, defined as endothelial-to-mesenchymal transition (EndMT). Invisible in onset and slow in progression, atherosclerosis (AS) is a potential contributor to various atherosclerotic cardiovascular diseases (ASCVD). By triggering AS, EndMT, the "initiator" of AS, induces the progression of ASCVD such as coronary atherosclerotic heart disease (CHD) and ischemic cerebrovascular disease (ICD), with serious clinical complications such as myocardial infarction (MI) and stroke.

Subcortical brain iron and its link to verbal memory in children with developmental language disorder.

Developmental Language Disorder (DLD) is a common neurodevelopmental condition characterized by significant difficulty with language learning, comprehension, and expression. The neurocognitive bases of DLD are underspecified but are thought to be related, in part, to altered basal ganglia (BG). The BG are known to have a high level of brain iron, which contributes to myelination and dopaminergic pathways among other physiological mechanisms.

Effect of intramuscular treatment with different iron dextran dosages and non-inferiority study to gleptoferron.

Background: Prevention of iron deficiency in suckling piglets by intramuscular injection of a standardized amount of iron dextran or gleptoferron in the first days of life can lead to over- or underdosage with respective health risks. Currently, combined iron products containing an active substance against coccidia are also used on farms. When using a combination product targeting two diseases, an adjustment of the necessary amount of iron to prevent anaemia in the frame of a farm-specific treatment protocol is not possible.

Cell-free hemoglobin released from hemolysis induces programmed cell death through iron overload and oxidative stress in grass carp (Ctenopharyngodon idella).

Intravascular hemolysis releases hemoglobin (Hb) from red blood cells under specific conditions, yet the effect of hemolysis in aquaculture systems remain poorly understood. In this study, a continuous hemolysis model for grass carp was established by injection of phenylhydrazine (PHZ) to investigate the mechanistic impacts of sustained hemolysis. PHZ-induced hemolysis altered liver color, and subsequent hematoxylin and eosin staining revealed substantial Hb accumulation in the head kidney, accompanied by inflammatory cell infiltration and vacuolization in liver tissue.

Hederagenin ameliorates ferroptosis-induced damage by regulating PPARα/Nrf2/GPX4 signaling pathway in HT22 cells: An in vitro and in silico study.

Background: Hederagenin (HG), derived from ivy seeds, is known to offer protection against Alzheimer's disease (AD). However, the specific molecular pathways through which it counters ferroptosis-induced neurotoxicity are not fully elucidated. This investigation seeks to delineate the processes by which HG mitigates neurotoxic effects in HT22 cells subjected to glutamate (Glu)-induced ferroptosis.

Progress on One-dimensional Vanadium Pentoxide-based Nanomaterials for Advanced Energy Storage ANSTEEL Research Institute of Vanadium & Titanium (Iron & Steel), China.

One-dimensional (1D) vanadium-based nanostructures have advantageous properties and are showing emerging critical applications in the fields of catalysis, smart devices, and electrochemical energy storage. We herein timely gave an overview of the 1D vanadium pentoxide (VO)-based nanomaterials for these promising applications, especially regarding the merits of different synthetic methods, structures and properties combined with recent research frontiers in advanced energy storage, including batteries, supercapacitors and like. The high capacity, high rate and flexibility of 1D VO-based nanomaterials endow them with great potential in high-energy-density, high-power energy devices and specific/harsh environments.

Determinants of anemia in school-going adolescents: a case study in Douala, Cameroon.

Context: Anemia is a medical condition resulting from a reduction in the number of red blood cells below the reference range. It is a major public health problem, particularly among adolescents, as it can have negative effects on cognitive performance, growth and reproduction. This study aims to assess the determinants of anemia among adolescents in schools in the city of Douala.