4 results match your criteria: "Institute Pasteur of Algeria[Affiliation]"
Amputation of a type II diabetic patient with cutaneous leishmaniasis due to Leishmania major.
BMC Infect Dis
December 2021
Parasitology-Mycology Department, Avicenne Hospital, AP-HP, 125, Route de Stalingrad, Bobigny Cedex, 93009, France.
Background: Leishmaniases are neglected tropical diseases of public health concern in Algeria. The immunocompromised patients with HIV, autoimmune diseases, or chronic alcohol abuse are at a higher risk of leishmaniasis. Herein, we present the case of an immunocompetent diabetic patient infected by Leishmania major, leading to life-threatening consequences.
View Article and Find Full Text PDFAssessment of oxidative/anti-oxidative markers and DNA damage profile induced by chemotherapy in algerian children with lymphoma.
Drug Chem Toxicol
March 2020
Department of Cellular and Molecular Biology, Cytokines and Nitric Oxide Synthases, Faculty of Biology, University Houari Boumediene USTHB, Algiers, Algeria.
Article Synopsis
- - This study evaluated oxidative stress and genetic damage caused by chemotherapy in 30 Algerian children with lymphoma compared to 50 healthy controls, measuring various biochemical markers and DNA damage.
- - Results showed significantly increased levels of malondialdehyde (MDA) and protein carbonyl (PC) and higher DNA damage in lymphoma patients, while superoxide dismutase (SOD) activity was notably lower than in healthy individuals.
- - There were strong positive correlations between DNA damage and both MDA and PC levels, and a negative correlation with SOD, indicating that chemotherapy may disrupt oxidative balance and contribute to increased oxidative stress in these patients.
Clinical variables and ethnicity may influenced by polymorphism of CAT -262C/T and MnSOD 47C/T antioxidant enzymes in Algerian type1 diabetes without complications.
Gene
September 2018
Department of Immunology, Institute Pasteur of Algeria, Algiers, Algeria.
The latest studies in Algeria show that the frequency of type 1 diabetes (T1D) without complications is lower than that with complications and represents a significant burden in terms of cost and treatment. For this reason, we are interested in uncomplicated type1 diabetes and risk factors that are related to polymorphisms of antioxidant enzymes in order to prevent its complications. A total of 260 blood samples of young Algerian adults were examined.
View Article and Find Full Text PDFAntimonial susceptibility and in vivo behaviour of Leishmania major isolates collected in Algeria before and after treatment.
Acta Trop
April 2018
IRD, Univ. Montpellier, InterTryp, Montpellier, France; IRD, Univ. Montpellier, MiVegec, Montpellier, France. Electronic address:
The repercussions of cutaneous leishmaniasis therapy on the behaviour and drug susceptibility of Leishmania major parasites is poorly documented. This study explored the link between antimonial susceptibility and in vivo behaviour in Leishmania major isolates collected before and after treatment in Algeria. This study was performed on 3 isolates collected from patients prior to treatment and paired with 3 isolates collected from the same patient after treatment failure.
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