8 results match your criteria: "Institute Materials Science[Affiliation]"

Article Synopsis
  • - This study focuses on creating biocompatible scaffolds using polylactic acid (PLA), calcium phosphate, and diatomaceous earth for bone regeneration, with a goal of improving cell adhesion and biodegradability.
  • - The optimal composite mix (20 PLA/1 CP/1 DE) showed almost no cytotoxicity following gamma sterilization and was tested for its mechanical properties, which were found to be similar to cancellous bone.
  • - Degradation tests over 13 weeks indicated stability without significant mass loss, and successful cell interaction was noted, suggesting potential for these 3D-printed scaffolds as alternatives to traditional bone implants.
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Aptamer decorated PDA@magnetic silica microparticles for bacteria purification.

Mikrochim Acta

April 2024

Department of Medical Biology, School of Medicine, Atilim University, Ankara, 06830, Türkiye.

One significant constraint in the advancement of biosensors is the signal-to-noise ratio, which is adversely affected by the presence of interfering factors such as blood in the sample matrix. In the present investigation, a specific aptamer binding was chosen for its affinity, while exhibiting no binding affinity towards non-target bacterial cells. This selective binding property was leveraged to facilitate the production of magnetic microparticles decorated with aptamers.

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The transition from quasistatic slip growth to dynamic rupture propagation constitutes one possible scenario to describe earthquake nucleation. If this transition is rather well understood for homogeneous faults, how the friction properties of may influence the of seismogenic faults remains largely unclear. Combining classical nucleation theory and concepts borrowed from condensed matter physics, we propose a comprehensive analytical framework that predicts the influence of heterogeneities of weakening rate on the nucleation length for linearly slip-dependent friction laws.

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Three dimensional (3D) supramolecules with giant cavities are attractive due to their wide range of applications. Herein, we used pentatopic terpyridine ligands with three types of coordination moieties to assemble two giant supramolecular hexagonal prisms with a molecular weight up to 42 608 and 43 569 Da, respectively. Within the prisms, two double-rimmed Kandinsky Circles serve as the base surfaces as well as the templates for assisting the self-sorting during the self-assembly.

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We study the effect of hindered aggregation on the island formation process in a one- (1D) and two-dimensional (2D) point-island model for epitaxial growth with arbitrary critical nucleus size i. In our model, the attachment of monomers to preexisting islands is hindered by an additional attachment barrier, characterized by length l_{a}. For l_{a}=0 the islands behave as perfect sinks while for l_{a}→∞ they behave as reflecting boundaries.

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Monodispersed, spherical gamma-Fe2O3 nanoparticles with controllable size in large-scale were prepared by thermolytic decomposition of FeCl3.6H2O in aliphatic amines. The nanoparticles gave very stable colloidal solution in organic solvents and can be easily converted to water-soluble by a very simple route.

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Dual-color fluorescence-burst analysis to probe protein efflux through the mechanosensitive channel MscL.

Biophys J

February 2007

Biochemistry Department, Groningen Biomolecular Science and Biotechnology Institute & Materials Science Centre, University of Groningen, Groningen, The Netherlands.

The mechanosensitive channel protein of large conductance, MscL, from Escherichia coli has been implicated in protein efflux, but the passage of proteins through the channel has never been demonstrated. We used dual-color fluorescence-burst analysis to evaluate the efflux of fluorescent labeled compounds through MscL. The method correlates the fluctuations in intensity of fluorescent labeled membranes and encapsulated (macro)molecules (labeled with second fluorophore) for each liposome diffusing through the observation volume.

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The oligomeric state and stability of the mannitol transporter, EnzymeII(mtl), from Escherichia coli: a fluorescence correlation spectroscopy study.

Protein Sci

August 2006

Department of Biochemistry and Biophysical Chemistry, Groningen Biomolecular Science and Biotechnology Institute & Materials Science Centreplus, University of Groningen, The Netherlands.

Article Synopsis
  • Numerous membrane proteins, like the E. coli mannitol transporter EII(mtl), function as oligomers for structural and functional purposes.
  • EII(mtl) is involved in transporting mannitol by phosphorylating it and releasing it into the cell, and its oligomerization state has been studied using fluorescence correlation spectroscopy.
  • Key findings reveal that EII(mtl) is a stable dimer in detergent solutions, with substrate binding destabilizing the complex while phosphorylation enhances its stability, although the two processes can interfere with each other.
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