118 results match your criteria: "Institut des Hautes Études Scientifiques & Centre National de la Recherche Scientifique[Affiliation]"
Commun Math Phys
December 2024
Institut des Hautes Études Scientifiques, Le Bois-Marie 35 rte de Chartres, 91440 Bures-sur-Yvette, France.
Some years ago, it was conjectured by the first author that the Chern-Simons perturbation theory of a 3-manifold at the trivial flat connection is a resurgent power series. We describe completely the resurgent structure of the above series (including the location of the singularities and their Stokes constants) in the case of a hyperbolic knot complement in terms of an extended square matrix (, )-series whose rows are indexed by the boundary parabolic -flat connections, including the trivial one. We use our extended matrix to describe the Stokes constants of the above series, to define explicitly their Borel transform and to identify it with state-integrals.
View Article and Find Full Text PDFMath Ann
April 2024
Institut des Hautes Études Scientifiques, Bures-sur-Yvette, France.
Biosystems
December 2024
Institute for Integrative Biology of the Cell (I2BC), CNRS, Université Paris-Sud, Université Paris Saclay, Gif-sur-Yvette, France; Komarov Botanical Institute RAS, St-Petersburg, Russia. Electronic address:
Morphogenesis, the complex process governing the formation of functional living structures, is regulated by a multitude of molecular mechanisms at various levels. While research in recent decades has shed light on many pathways involved in morphogenesis, none singularly accounts for the precise geometric shapes of organisms and their components in space. To bridge this conceptual gap between specific molecular mechanisms and the creation of definitive morphological forms, we have proposed the "epigenetic code hypothesis" in our previous work.
View Article and Find Full Text PDFProbab Theory Relat Fields
August 2024
Research Unit of Probability, Faculty of Mathematics and Geoinformation, Institute of Statistics and Mathematical Methods in Economics, TU Wien, Wiedner Hauptstraße 8-10, 1040 Vienna, Austria.
Phys Rev Lett
August 2024
Université Paris-Saclay, CNRS, CEA, Institut de Physique Théorique, 91191, Gif-sur-Yvette, France and Institut des Hautes Études Scientifiques, 91440, Bures-sur-Yvette, France.
We give an elementary proof of the following property of unitary, interacting four-dimensional N=2 superconformal field theories: At large central charge c, there exist at least sqrt[c] single-trace, scalar superconformal primary operators with dimensions Δ≲sqrt[c] (suppressing multiplicative logarithmic corrections). This follows from a stronger, more refined bound on the spectral density in terms of the asymptotic growth rate of the central charge. The proof employs known results on the structure of Coulomb branch operators.
View Article and Find Full Text PDFArch Ration Mech Anal
February 2024
Institut des Hautes Études Scientifiques, Bures-sur-Yvette, France.
We obtain a new formula for the Loewner energy of Jordan curves on the sphere, which is a Kähler potential for the essentially unique Kähler metric on the Weil-Petersson universal Teichmüller space, as the renormalised energy of moving frames on the two domains of the sphere delimited by the given curve.
View Article and Find Full Text PDFPhys Rev Lett
March 2024
Departament de Física Quàntica i Astrofísica, Institut de Ciències del Cosmos, Universitat de Barcelona, Martí i Franquès 1, E-08028 Barcelona, Spain.
The precise modeling of binary black hole coalescences in generic planar orbits is a crucial step to disentangle dynamical and isolated binary formation channels through gravitational-wave observations. The merger regime of such coalescences exhibits a significantly higher complexity compared to the quasicircular case, and cannot be readily described through standard parametrizations in terms of eccentricity and anomaly. In the spirit of the effective one body formalism, we build on the study of the test-mass limit, and introduce a new modeling strategy to describe the general-relativistic dynamics of two-body systems in generic orbits.
View Article and Find Full Text PDFCommun Math Phys
November 2023
Department of Mathematics, ETH Zurich, Group 3 HG G 66.5 Rämistrasse 101, 8092 Zurich, Switzerland.
In this paper, we investigate the behaviour of statistical physics models on a book with pages that are isomorphic to half-planes. We show that even for models undergoing a continuous phase transition on , the phase transition becomes discontinuous as soon as the number of pages is sufficiently large. In particular, we prove that the Ising model on a three pages book has a discontinuous phase transition (if one allows oneself to consider large coupling constants along the line on which pages are glued).
View Article and Find Full Text PDFPhys Rev Lett
July 2023
Institut für Gravitationsphysik, Leibniz Universität Hannover and Max-Planck-Institut für Gravitationsphysik (Albert-Einstein-Institut), Callinstraße 38, 30167 Hannover, Germany.
In this Letter, we present the design and performance of the frequency-dependent squeezed vacuum source that will be used for the broadband quantum noise reduction of the Advanced Virgo Plus gravitational-wave detector in the upcoming observation run. The frequency-dependent squeezed field is generated by a phase rotation of a frequency-independent squeezed state through a 285 m long, high-finesse, near-detuned optical resonator. With about 8.
View Article and Find Full Text PDFPhys Rev Lett
June 2023
Institut für Theoretische Physik und Astrophysik and Würzburg-Dresden Cluster of Excellence ct.qmat, Universität Würzburg, 97074 Würzburg, Germany.
The fermion disorder operator has been shown to reveal the entanglement information in 1D Luttinger liquids and 2D free and interacting Fermi and non-Fermi liquids emerging at quantum critical points (QCPs) [W. Jiang et al., arXiv:2209.
View Article and Find Full Text PDFPhys Rev Lett
June 2023
Department of Physics, Harvard University, Cambridge, Massachusetts 02138, USA.
The bulk-boundary correspondence relates topologically protected edge modes to bulk topological invariants and is well understood for short-range free-fermion chains. Although case studies have considered long-range Hamiltonians whose couplings decay with a power-law exponent α, there has been no systematic study for a free-fermion symmetry class. We introduce a technique for solving gapped, translationally invariant models in the 1D BDI and AIII symmetry classes with α>1, linking together the quantized winding invariant, bulk topological string-order parameters, and a complete solution of the edge modes.
View Article and Find Full Text PDFJ Math Biol
May 2023
Simons Center for Geometry and Physics, Stony Brook University, Stony Brook, NY, 11794, USA.
Some genes can promote or repress their own expressions, which is called autoregulation. Although gene regulation is a central topic in biology, autoregulation is much less studied. In general, it is extremely difficult to determine the existence of autoregulation with direct biochemical approaches.
View Article and Find Full Text PDFArXiv
March 2023
Simons Center for Geometry and Physics, Stony Brook University, Stony Brook, New York, United States of America.
The expression of one gene might be regulated by its corresponding protein, which is called autoregulation. Although gene regulation is a central topic in biology, autoregulation is much less studied. In general, it is extremely difficult to determine the existence of autoregulation with direct biochemical approaches.
View Article and Find Full Text PDFPLoS One
November 2022
Department of Computational Medicine, University of California, Los Angeles, California, United States of America.
If several relatives died with no will, the order of their deaths could affect the inheritance result. When the order of death is unknown, there are three approaches to determine the inheritance result in this simultaneous death situation: apply an inheritance method that is not affected by the order of death; artificially assign the order of death; stipulate that persons with unknown orders do not inherit each other. The last approach is adopted by the current French Civil Code (denoted as the French Approach).
View Article and Find Full Text PDFCommun Math Phys
September 2022
Université de Genéve, Geneva, Switzerland.
In this paper, we provide new proofs of the existence and the condensation of Bethe roots for the Bethe Ansatz equation associated with the six-vertex model with periodic boundary conditions and an arbitrary density of up arrows (per line) in the regime . As an application, we provide a short, fully rigorous computation of the free energy of the six-vertex model on the torus, as well as an asymptotic expansion of the six-vertex partition functions when the density of up arrows approaches 1/2. This latter result is at the base of a number of recent results, in particular the rigorous proof of continuity/discontinuity of the phase transition of the random-cluster model, the localization/delocalization behaviour of the six-vertex height function when and , and the rotational invariance of the six-vertex model and the Fortuin-Kasteleyn percolation.
View Article and Find Full Text PDFPhys Rev Lett
September 2022
Faculty of Aerospace Engineering, Delft University of Technology, Kluyverweg 1, 2629 HS Delft, Netherlands.
The MICROSCOPE mission was designed to test the weak equivalence principle (WEP), stating the equality between the inertial and the gravitational masses, with a precision of 10^{-15} in terms of the Eötvös ratio η. Its experimental test consisted of comparing the accelerations undergone by two collocated test masses of different compositions as they orbited the Earth, by measuring the electrostatic forces required to keep them in equilibrium. This was done with ultrasensitive differential electrostatic accelerometers onboard a drag-free satellite.
View Article and Find Full Text PDFPhys Rev Lett
August 2022
The Pennsylvania State University, University Park, Pennsylvania 16802, USA.
Sci Rep
August 2022
University of Illinois, Chicago, USA.
This paper presents a novel biologically-inspired explore-and-fuse approach to solving a large array of problems. The inspiration comes from Physarum, a unicellular slime mold capable of solving the traveling salesman and Steiner tree problems. Besides exhibiting individual intelligence, Physarum can also share information with other Physarum organisms through fusion.
View Article and Find Full Text PDFPhys Rev Lett
July 2022
Laboratoire de Physique de l'Ecole normale supérieure, ENS, Université PSL, CNRS Sorbonne Université, Université de Paris, F-75005 Paris, France.
By the Parisi-Sourlas conjecture, the critical point of a theory with random field (RF) disorder is described by a supersymmeric (SUSY) conformal field theory (CFT), related to a d-2 dimensional CFT without SUSY. Numerical studies indicate that this is true for the RF ϕ^{3} model but not for the RF ϕ^{4} model in d<5 dimensions. Here we argue that the SUSY fixed point is not reached because of new relevant SUSY-breaking interactions.
View Article and Find Full Text PDFPLoS Comput Biol
July 2022
Institute for Systems Biology, Seattle, Washington, United States of America.
Intratumor cellular heterogeneity and non-genetic cell plasticity in tumors pose a recently recognized challenge to cancer treatment. Because of the dispersion of initial cell states within a clonal tumor cell population, a perturbation imparted by a cytocidal drug only kills a fraction of cells. Due to dynamic instability of cellular states the cells not killed are pushed by the treatment into a variety of functional states, including a "stem-like state" that confers resistance to treatment and regenerative capacity.
View Article and Find Full Text PDFAlgorithms Mol Biol
June 2022
Department of Computational Medicine, University of California, Los Angeles, USA.
Background: The early development of a zygote can be mathematically described by a developmental tree. To compare developmental trees of different species, we need to define distances on trees. If children cells after a division are not distinguishable, developmental trees are represented by the space [Formula: see text] of rooted trees with possibly repeated labels, where all vertices are unordered.
View Article and Find Full Text PDFProc Natl Acad Sci U S A
May 2022
Department of Mathematics, The Ohio State University, Columbus, OH 43210.
SignificanceWe show that the eigenvalues of the self-adjoint extension (introduced by A.C. in 1998) of the prolate spheroidal operator reproduce the UV behavior of the squares of zeros of the Riemann zeta function, and we construct an isospectral family of Dirac operators whose spectra have the same UV behavior as those zeros.
View Article and Find Full Text PDFTheory Biosci
June 2022
IHES: Institut des Hautes Etudes Scientifiques, Bures-sur-Yvette, France.
J Theor Biol
April 2022
Laboratory of Genetics, The Rockefeller University, New York 10065, NY, USA.
In this paper, we conduct theoretical analyses on inferring the structure of gene regulatory networks. Depending on the experimental method and data type, the inference problem is classified into 20 different scenarios. For each scenario, we discuss the problem that with enough data, under what assumptions, what can be inferred about the structure.
View Article and Find Full Text PDFVaccines (Basel)
December 2021
Institut des Hautes Etudes Scientifiques, 35 Route des Chartres, 91440 Bures-sur-Yvette, France.
We observe that a residue R of the spike glycoprotein of SARS-CoV-2 that has mutated in one or more of the current variants of concern or interest, or under monitoring, rarely participates in a backbone hydrogen bond if R lies in the S1 subunit and usually participates in one if R lies in the S2 subunit. A partial explanation for this based upon free energy is explored as a potentially general principle in the mutagenesis of viral glycoproteins. This observation could help target future vaccine cargos for the evolving coronavirus as well as more generally.
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