1 results match your criteria: "Institut Universitaire de Cardiologie et de Pneumology[Affiliation]"
Increased T-cell survival by structural bronchial cells derived from asthmatic subjects cultured in an engineered human mucosa.
J Allergy Clin Immunol
March 2008
Centre de Recherche, Hôpital Laval, Institut Universitaire de Cardiologie et de Pneumology, Laval, Quebec, Canada.
Background: Interaction between lymphocytes and structural cells has been proposed as a key factor in regulating inflammation in asthma.
Objective: This study was designed to investigate the effect of epithelial cells and fibroblasts on T-lymphocyte survival by using a 3-dimensional tissue-engineered model.
Methods: Engineered human bronchial mucosal tissues were produced by using fibroblasts, epithelial cells, and autologous T cells from asthmatic and healthy donors.