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Pathophysiology and classification of iron overload diseases; update 2018.
Transfus Clin Biol
February 2019
Service d'hématologie clinique et de thérapie cellulaire, faculté de médecine, hôpital Saint-Antoine, Sorbonne université, Inserm UMRs-938 centre de recherche Saint-Antoine, AP-HP, 75012 Paris, France. Electronic address:
Iron overload pathophysiology has benefited from significant advances in the knowledge of iron metabolism and in molecular genetics. As a consequence, iron overload nosology has been revisited. The hematologist may be confronted to a number of iron overload syndromes, from genetic or acquired origin.
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