2 results match your criteria: "Inserm UMR-S 942 and Paris Diderot University[Affiliation]"
QSOX1, a novel actor of cardiac protection upon acute stress in mice.
J Mol Cell Cardiol
June 2018
Inserm UMR-S 942 and Paris Diderot University, Paris, France.. Electronic address:
QSOX1, a sulfhydryl oxidase, was shown to be upregulated in the heart upon acute heart failure (AHF). The aim of the study was to unravel QSOX1 roles during AHF. We generated and characterized mice with QSOX1 gene deletion.
View Article and Find Full Text PDFLoss of Notch3 Signaling in Vascular Smooth Muscle Cells Promotes Severe Heart Failure Upon Hypertension.
Hypertension
August 2016
From the Inserm UMR-S 942 and Paris Diderot University, Paris, France (H.R., A.M., M.B., F.A., L.F., R.M., E.P., A.C.-S., C.D., N.V., J.-L.S.); Department of Cardiology, Lariboisière Hospital, Paris, France (A.C.-S.); and Inserm UMR-S 1155 and Pierre and Marie Curie University, Paris, France (C.C.).
Hypertension, which is a risk factor of heart failure, provokes adaptive changes at the vasculature and cardiac levels. Notch3 signaling plays an important role in resistance arteries by controlling the maturation of vascular smooth muscle cells. Notch3 deletion is protective in pulmonary hypertension while deleterious in arterial hypertension.
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