402 results match your criteria: "Inserm U1290 - universite Lyon 1[Affiliation]"
Can J Cardiol
August 2024
Université de Lorraine, INSERM 1433, Centre d'Investigations Cliniques Plurithématique, CHRU de Nancy, France; INI-CRCT, F-CRIN Network, Nancy, France; REICATRA, Université de Lorraine, Vandœuvre-lès-Nancy, France. Electronic address:
J Cyst Fibros
August 2024
Respiratory Medicine and Cystic Fibrosis National Reference Centre, Cochin Hospital, Assistance Publique Hôpitaux de Paris (AP-HP), Paris, France; Université Paris-Cité, Institut Cochin, Inserm U1016, Paris, France; ERN-Lung CF network, Frankfurt, Germany.
Rev Med Interne
November 2024
Service de médecine interne, centre de référence maladies auto-immunes et auto-inflammatoires systémiques rares d'Île-de-France, de l'Est et de l'Ouest, hôpital Cochin, Assistance publique-Hôpitaux de Paris, Paris-Centre, université Paris Cité, Paris, France.
Introduction: The 2017 reform of the third cycle of medical studies (R3C) was accompanied by modifications in the formats and number of specialty diplomas. The aim of this study was to investigate the evolution of the choice of the internal medicine and clinical immunology specialty before and after 2017.
Methods: We used the median ranking and its evolution, as well as incoming and outgoing remorse rights, as markers of attractiveness.
Arch Dis Child
November 2024
University of Clermont Auvergne, Clermont-Ferrand, France.
Objective: The objective is to explore the journey to diagnosis and referral pathway from the onset of symptoms to the initial assessments at paediatric rheumatology (PR) centres, based on the experience of children with juvenile idiopathic arthritis (JIA) and their parents.
Design: We conducted a qualitative study with semistructured interviews. Our qualitative and phenomenological procedure applied interpretative phenomenological analysis.
JMIR Public Health Surveill
August 2024
Health Systemic Process Laboratory (P2S), UR4129, University Claude Bernard Lyon 1, University of Lyon, Lyon, France.
Background: In 2022, the World Health Organization highlighted the alarming state of oral health (OH) worldwide and urged action to include OH in initiatives on noncommunicable diseases. The population needs improved OH skills and attitudes and an adequate level of OH literacy (OHL) and general health literacy (HL). The implementation of health promotion actions in the workplace, which is a part of most people's lives, appears to be an opportunity.
View Article and Find Full Text PDFDigit Health
August 2024
Research on Healthcare Performance RESHAPE, INSERM U1290, Université Claude Bernard Lyon 1, Lyon, France.
Background: During the hospital-to-home transition, stroke survivors and their caregivers face a significant lack of support and information which impacts their psychosocial recovery. We aimed to co-design a program combining individual support by a trained case-manager (dedicated professional providing individual support) and an online information platform to address needs of stroke survivors and caregivers.
Methods: A two-step methodology was used.
Aims: This systematic review and meta-analysis aimed to assess the efficacy of NMDA antagonists in ASD (Autism Spectrum Disorder) on the core (communication and social interaction, repetitive behavior) and associated symptoms (irritability) of ASD, as well as their safety.
Methods: PubMed, CENTRAL, CINHAL, EMBASE, and PsycINFO databases were searched until November 2023. Two authors independently selected the studies and extracted data.
J Cardiothorac Vasc Anesth
October 2024
Service d'Anesthésie-Réanimation, Hôpital Louis Pradel, Hospices Civils de Lyon, Bron Cedex, France; Faculté de Médecine Lyon Est, Université Claude Bernard Lyon 1, Lyon Cedex, France; Laboratoire CarMeN, Inserm UMR 1060, Université Claude Bernard Lyon 1, Bron Cedex, France.
Factors influencing the implementation of parent-mediated intervention are insufficiently studied. This study examines for the first-time factors of implementation into clinical practice across the world of Pediatric Autism Communication Therapy, an internationally disseminated, evidence-based, parent-mediated therapy. From both the parents' and the professionals' perspectives, parents attitudes (e.
View Article and Find Full Text PDFAlzheimers Res Ther
July 2024
Pharmacy Department, Charpennes Hospital, Hospices Civils de Lyon, 27 Rue Gabriel Péri, 69100, Villeurbanne, France.
Background: Long-term exposure to anticholinergic and sedative drugs could be a modifiable risk factor for cognitive decline. The objective of this study was to measure the association between previous cumulative anticholinergic and sedative drug exposure (Drug Burden Index) and cognitive decline.
Methods: A cohort study (MEMORA cohort) was conducted in a French memory clinic for patients attending a consultation between November 2014 and December 2020, with at least 2 Mini-Mental State Examination (MMSE) measurements (≥ 6 months apart) and available medication data from the local Primary Health Insurance Fund database (n = 1,970).
JCO Oncol Pract
July 2024
Department of Medical Oncology, Hospices Civils de Lyon, Pierre-Bénite, France.
Purpose: The management of immune-related adverse events (irAEs) requires multidisciplinary boards to handle complex cases. This study aimed to examine the evolving practices of the IMMUCARE board and to evaluate its impact on clinical practices.
Materials And Methods: The IMMUCARE board gathers oncologists and organ specialists from the Cancerology Institute of the Lyon University Hospital since 2018.
BMC Prim Care
July 2024
Service Recherche Et Épidémiologie Clinique, Hospices Civils de Lyon, Pole de Santé Publique, 162 Avenue Lacassagne, Lyon, 69003, France.
Background: While patient safety incident reporting is of key importance for patient safety in primary care, the reporting rate by healthcare professionals remains low. This study aimed to assess the effectiveness of a risk management program in increasing the reporting rate within multiprofessional primary care facilities.
Methods: A nation-wide cluster-randomised controlled trial was performed in France, with each cluster defined as a primary care facility.
BMC Public Health
July 2024
RESHAPE - Research on Healthcare Performance Lab, Inserm U1290, Claude Bernard Lyon 1 University, Lyon, 69424, France.
Background: A previous study reported significant excess mortality among non-COVID-19 patients due to disrupted surgical care caused by resource prioritization for COVID-19 cases in France. The primary objective was to investigate if a similar impact occurred for medical conditions and determine the effect of hospital saturation on non-COVID-19 hospital mortality during the first year of the pandemic in France.
Methods: We conducted a nationwide population-based cohort study including all adult patients hospitalized for non-COVID-19 acute medical conditions in France between March 1, 2020 and 31 May, 2020 (1st wave) and September 1, 2020 and December 31, 2020 (2nd wave).
Eur J Neurol
October 2024
Research on Healthcare Performance RESHAPE, INSERM U1290, Université Claude Bernard Lyon 1, Lyon, France.
Ann Oncol
September 2024
Department of Internal Medicine and Medical Specialties (DIMI), School of Medicine, University of Genova, Genova, Italy; Medical Oncology Department, U.O.C. Clinica di Oncologia Medica, IRCCS Ospedale Policlinico San Martino, Genova, Italy. Electronic address:
Background: Hormone receptor expression is a known positive prognostic and predictive factor in breast cancer; however, limited evidence exists on its prognostic impact on prognosis of young patients harboring a pathogenic variant (PV) in the BRCA1 and/or BRCA2 genes.
Patients And Methods: This international, multicenter, retrospective cohort study included young patients (aged ≤40 years) diagnosed with invasive breast cancer and harboring germline PVs in BRCA genes. We investigated the impact of hormone receptor status on clinical behavior and outcomes of breast cancer.
Med Educ Online
December 2024
European Society of Anesthesiology and Intensive Care, Examinations Committee, Brussels, Belgium.
The COVID-19 pandemic triggered transformations in academic medicine, rapidly adopting remote teaching and online assessments. Whilst virtual environments show promise in evaluating medical knowledge, their impact on examiner workload is unclear. This study explores examiner's workload during different European Diploma in Anaesthesiology and Intensive Care Part 2 Structured Oral Examinations formats.
View Article and Find Full Text PDFAnn Intensive Care
May 2024
Département d'Anesthésie Réanimation, Centre Hospitalier Lyon Sud, Hospices Civils de Lyon, Lyon, France.
J Nurs Care Qual
May 2024
Author Affiliations: Department of Anesthesiology and Intensive Care (Dr Wallet, and Messrs Bonnet, Thiriaud, and Caillet, Dr Piriou, Dr Vacheron, and Dr Friggeri), University Hospital Lyon Sud, Hospices Civils de Lyon, Pierre-Bénite, France; RESHAPE-INSERM U1290 (Dr Wallet and Drs Piriou and Dziadzko), Claude Bernard Lyon 1 University, Lyon, France; Department of Biostatistics, Bioinformatics and Public Health (Dr Vacheron), Hospices Civils de Lyon, Lyon, France; International Research Center in Infectiology (Dr Friggeri), INSERM U1111, CNRS UMR5308, ENS Lyon, Claude Bernard Lyon 1 University, Lyon, France; and Department of Anesthesiology (Dr Dziadzko), Intensive Care and Pain Management, University Hospital Croix Rousse, Hospices Civils de Lyon, Lyon, France.
Front Psychol
May 2024
Occupational Health and Medicine Department-CRPPE Hospices Civils de Lyon, Lyon, France.
Introduction: The mental health of residents is a growing significant concern, particularly with respect to hospital and university training conditions. Our goal was to assess the professional, academic, and psychological determinants of the mental health status of all residents of the academy of Lyon, France.
Materials And Methods: The Health Barometer of Lyon Subdivision Residents (BASIL) is an initiative which consists in proposing a recurrent online survey to all residents in medicine, pharmacy, and dentistry, belonging to the Lyon subdivision.
J Eur Acad Dermatol Venereol
May 2024
Research on Healthcare Performance (RESHAPE), INSERM U1290, Université Claude Bernard Lyon 1, Lyon, France.
Background: Despite the French pregnancy prevention program (PPP), a considerable number of pregnancies are potentially exposed to oral isotretinoin. New measures were taken by the French Medicines Agency, including the restriction of initial isotretinoin prescriptions to dermatology specialists in May 2015 and a new information campaign on teratogenicity in January 2019.
Objectives: The aims were to: describe, between 2014 and 2021, compliance with PPP recommendations: isotretinoin use as a second-line treatment, first prescription by a dermatology specialist, monthly prescription renewal and pregnancy testing (PT); assess the effect of the 2015 and 2019 measures on PT compliance; and identify the determinants of PT noncompliance.
Sci Rep
May 2024
Centre Max Weber, UMR 5283, Institut des Sciences de l'Homme, 69363, Lyon, France.
This study aimed to explore the perception of an underutilised collaborative information system through qualitative research, utilizing semi-structured, in-depth interviews with independent midwives and physician. PROSPERO, is a collaborative information system designed to bridge the communication gap between community-based healthcare workers and hospital-based care teams for parturients in Lyon, France. Through 27 semi-structured in-depth interviews with midwives, obstetricians, and general practitioners, we identified key themes related to the system's adoption: implementation challenges, utilisation barriers, interprofessional dynamics, and hidden variables affecting system use.
View Article and Find Full Text PDFCrit Care
May 2024
Department of Anesthesia and Intensive Care, Lyon Sud Hospital, Hospices Civils de Lyon, Pierre-Bénite, France.
Background: Critically injured patients need rapid and appropriate hemostatic treatment, which requires prompt identification of trauma-induced coagulopathy (TIC) upon hospital admission. We developed and validated the performance of a clinical score based on prehospital resuscitation parameters and vital signs at hospital admission for early diagnosis of TIC.
Methods: The score was derived from a level-1 trauma center registry (training set).
Sci Rep
May 2024
Lyon Est School of Medicine, Université Lyon 1, Lyon, France.
Objective structured clinical examination (OSCE) is a valid method to evaluate medical students' competencies. The present cross-sectional study aimed at determining how students' coping and health-related behaviors are associated with their psychological well-being and performance on the day of the OSCE. Fourth-year medical students answered a set of standardized questionnaires assessing their coping (BCI) and health-related behaviors before the examination (sleep PSQI, physical activity GPAQ).
View Article and Find Full Text PDFCancer
August 2024
Department of Internal Medicine and Medical Specialties (DiMI), School of Medicine, University of Genova, Genova, Italy.