3 results match your criteria: "Innovative Centre of the Faculty of Chemistry Ltd.[Affiliation]"
Implementation of multiobjective decision-making algorithms and image analysis in HPTLC-guided extraction optimization of natural products.
J Chromatogr A
November 2024
Innovative Centre of the Faculty of Chemistry Ltd., Studentski trg 12-16, 1100 Belgrade, Serbia.
Article Synopsis
- A new method combining high-performance thin-layer chromatography (HPTLC) and digital image analysis was developed for effectively monitoring and optimizing extraction processes at a low cost.
- Four multicriteria decision-making (MCDM) techniques were compared to analyze the extraction of compounds from green tea leaves, finding that Derringer's desirability, TOPSIS, and PROMETHEE-2 produced consistent rankings for the extracts.
- The study concluded that optimal extraction conditions were found using moderate ethanol (73%) and extraction times (46 min), highlighting the value of MCDM algorithms in managing multiple chromatographic responses in extraction optimization.
Multiobjective optimization of effect-directed planar chromatography as a promising tool for fast selection of polypotent natural products.
J Chromatogr A
September 2024
University of Belgrade - Faculty of Chemistry, Studentski trg 12-16, Belgrade 1100, Serbia. Electronic address:
A new method for efficiently selecting polypotent natural products is proposed in this study. The method involves using effect-directed HPTLC data and multiobjective optimization algorithms to extract chromatographic signals from HPTLC bioassay images. Three different multiobjective optimization methods, namely Derringer's desirability approach, Technique for order of preference by similarity to ideal solution (TOPSIS), and Sum of ranking differences (SRD), were applied to the chromatographic signals.
View Article and Find Full Text PDFAntibacterial Activities of Extracts and Their Synergistic Effects with the Antistaphylococcal Drug AFN-1252.
Foods
May 2024
Micalis, AgroParisTech, National Research Institute for Agriculture, Food and the Environment (INRAE), University Paris-Saclay, UMR 1319, 78350 Jouy en Josas, France.
, commonly known as the button mushroom, has attracted attention for its biological properties, including antimicrobial activities. Here, we evaluated the efficacy of ethanolic and acetonic extracts from white and brown against different bacterial strains, including antibiotic-resistant strains. Bioautography and principal component analysis identified the most active antibacterial compounds for each of the tested bacteria and indicated the main markers responsible for the strain-specific effects.
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