Experimental study on damage of slope under drying and wetting cycle based on DC electric method.

In order to investigate the seepage law and crack development characteristics of dump slopes, as well as the impact on slope stability during drying and wetting cycles, a simulation test slope system was constructed in a rainfall environment, specifically designed to mimic the engineering conditions of dump slope. The apparent resistivity response formula for the seepage and crack development processes was derived based on the three-phase medium theory of rock-soil bodies and Maxwell's conductivity formula. The geoelectric field characteristics pertaining to slope damage and the corresponding patterns of alteration were comprehensively investigated.

Safety and efficacy of peficitinib in Asian patients with rheumatoid arthritis who had an inadequate response or intolerance to methotrexate: results of a multicenter, randomized, double-blind, placebo-controlled phase 3 study.

Background: The efficacy and safety of the oral Janus kinase inhibitor peficitinib were investigated in Asian patients with rheumatoid arthritis (RA).

Methods: In this double-blind, phase 3 study, patients from mainland China, Korea, and Taiwan with RA and an inadequate response/intolerance to methotrexate were randomized (1:1:1) to once-daily placebo (N = 128), peficitinib 100 mg (N = 129), or 150 mg (N = 128) in combination with non-biologic DMARDs. At Week 24, patients receiving placebo switched to peficitinib 100 mg or 150 mg.

The global state of research in stem cells therapy for spinal cord injury (2003-2022): a visualized analysis.

Objective: Our study aimed to visualize the global status and frontiers in stem cell therapy for spinal cord injury by using bibliometric methodology.

Methods: Publication citation information related to stem cell therapy for spinal cord injury (SCI) studies between 2003 and 2022 was retrieved from the Web of Science Core Collection database. For the visualized study, VOS viewer software and Graph Pad Prism 9.

Bismuth Ferrite-Based Lead-Free High-Entropy Piezoelectric Ceramics.

Piezoelectric ceramics, as essential components of actuators and transducers, have captured significant attention in both industrial and scientific research. The "entropy engineering" approach has been demonstrated to achieve excellent performance in lead-based materials. In this study, the "entropy engineering" approach was employed to introduce the morphotropic phase boundary (MPB) into the bismuth ferrite (BF)-based lead-free system.

Sodium butyrate restricts neutrophils migration and NETs formation through reducing macrophage-derived CXCL16 in calculous cholecystitis.

Background: Neutrophil extracellular traps (NETs) havebeen demonstrated to initiate gallstone formation. Cholecystitis is a common complication of gallstones. As short-chain fatty acids (SCFAs), Butyrate acid has anti-inflammatory effects and alleviates cholesterol gallstones.

Discovering Cathodic Biocompatibility for Aqueous Zn-MnO Battery: An Integrating Biomass Carbon Strategy.

Developing high-performance aqueous Zn-ion batteries from sustainable biomass becomes increasingly vital for large-scale energy storage in the foreseeable future. Therefore, γ-MnO uniformly loaded on N-doped carbon derived from grapefruit peel is successfully fabricated in this work, and particularly the composite cathode with carbon carrier quality percentage of 20 wt% delivers the specific capacity of 391.2 mAh g at 0.

Relationship between four insulin resistance surrogates and left ventricular hypertrophy among hypertensive adults: a case-control study.

Background: Hypertension-induced left ventricular hypertrophy (LVH) is intricately linked to insulin resistance (IR). This research aimed to elucidate the relationship of advanced indices, namely the triglyceride-glucose (TyG) index, the TyG adjusted for body mass index (TyG-BMI), the triglycerides-to-high-density lipoprotein cholesterol ratio (TG/HDL-c), and the metabolic score for IR (METS-IR), with LVH in hypertensive cohorts.

Methods: This analytical case-control investigation encompassed 800 individuals aged 18 or above from the Cardiology Department of the Second Affiliated Hospital of Baotou Medical College over a span from January 2021 to April 2022.

Distribution, sources, partition behavior and risk assessment of polycyclic aromatic hydrocarbons (PAHs) in the waters and sediments of Lake Ulansuhai, China.

This study represents the first comprehensive investigation of 16 polycyclic aromatic hydrocarbons (PAHs) in the waters and sediments of Lake Ulansuhai. It explores their occurrence, sources, transport behavior, and associated risks to human health and ecosystems. The results revealed that concentrations of ∑PAHs in dissolved phase and sediment with no significant seasonal differences.

Roxadustat and Oral Iron Absorption in Chinese Patients with Anemia of Chronic Kidney Disease: A Randomized, Open-Label, Phase 4 Study (ALTAI).

Introduction: Anemia of chronic kidney disease (CKD) has a high incidence and is associated with many disease conditions. Iron dysmetabolism is an important contributor to anemia in CKD patients.

Methods: ALTAI, a randomized, active-controlled, phase 4 trial, investigated the efficacy of roxadustat versus recombinant human erythropoietin (rHuEPO) on gastrointestinal iron absorption in patients with anemia of CKD (stage 4/5).

Study of the optic nerve in patients with type 2 diabetic retinopathy by shear-wave elastography.

Aim: To investigate the clinical value of two-dimensional shear-wave elastography (2D-SWE) in detecting optic nerve elasticity and in-frame adipose tissue elasticity in patients with type 2 diabetic retinopathy (DR).

Materials And Methods: 2D-SWE was used to detect SWE values of the optic nerve and adipose tissue in adjacent optic nerve frames in 30 healthy participants, 30 patients with diabetic non-retinopathy (NDR), 35 patients with non-proliferative diabetic retinopathy (NPDR), and 30 patients with proliferative diabetic retinopathy (PDR). The correlation between SWE values and blood glucose, blood lipid, age, body mass index (BMI) was analysed.

Effects of long-term afforestation on soil water and carbon in the Alxa Plateau.

Plantations in dry and semi-arid areas significantly affect the soil's ability to store carbon and maintain a stable water balance. It is yet unclear, though, how planted trees in these regions might impact the soil's carbon and water levels. As a forest ages, it is unknown how soil water and soil carbon interact with one another.

[MOR106 alleviates inflammation in mice with atopic dermatitis by blocking the JAK2/STAT3 signaling pathway and inhibiting IL-17C-mediated Tfh cell differentiation].

Objective To explore the significance of interleukin-17C(IL-17C)-mediated follicular helper T cell (Tfh) differentiation in atopic dermatitis (AD) model. Methods BALB/c mice were divided into control group, AD model group, low-dose MOR106 (anti-IL-17C huIgG1)(MDR106-L)treatment group and high-dose MOR106 (MOR106-H) treatment group, 8 mice in each group. Except for the control group, all the other groups were treated with 2, 4- dinitrochlorobenzene (DNCB) to establish AD models.

Magnetic Bimetallic Heterointerface Nanomissiles with Enhanced Microwave Absorption for Microwave Thermal/Dynamics Therapy of Breast Cancer.

Microwave thermotherapy (MWT) has shown great potential in cancer treatment due to its deep tissue penetration and minimally invasive nature. However, the poor microwave absorption (MA) properties of the microwave thermal sensitizer in the medical frequency band significantly limit the thermal effect of MWT and then weaken the therapeutic efficacy. In this paper, a Ni-based multilayer heterointerface nanomissile of MOFs-Ni-Ru@COFs (MNRC) with improved MA performance in the desired frequency band via introducing magnetic loss and dielectric loss is developed for MWT-based treatment.

Study on the Preparation and Properties of Vegetation Lightweight Porous Concrete.

The objective of this study is to formulate vegetated light porous concrete (VLPC) through the utilization of various cementing materials, the design of porosity, and the incorporation of mineral additives. Subsequently, the study aims to assess and analyze key properties, including the bulk density, permeability coefficient, mechanical characteristics, and alkalinity. The findings indicate a linear decrease in the volume weight of VLPC as the designed porosity increases.

Improved adaptive-phase fuzzy high utility pattern mining algorithm based on tree-list structure for intelligent decision systems.

With the rapid development of AI and big data mining technologies, computerized medical decision-making has become increasingly prominent. The aim of high-utility pattern mining (HUPM) is to discover meaningful patterns in medical databases that contribute to maximizing the utility from the perspective of diagnosis. However, HUPM pays less attention to the interpretability and explainability of these patterns in medical decision-making scenarios.

Highly efficient and stable CsMnZnBr@SiO for wide color gamut backlight displays.

Mn-based perovskites have become a new candidate material for backlight display applications. However, low efficiency and poor stability are the key problems limiting the application of Mn-based perovskites. In this work, Zn-doped and SiO-encapsulated CsMnBr, denoted as CsMnZnBr@SiO (CMZBS), was successfully synthesized to improve the photoluminescence quantum yield (PLQY) and stability.

New hope for esophageal stricture prevention: A prospective single-center trial on acellular dermal matrix.

Background: Given the high incidence of esophageal cancer in China, an increasing number of patients there are undergoing endoscopic mucosal dissection (ESD). Although the 5-year survival rate after ESD can exceed 95%, esophageal stricture, the most common and serious postoperative complication, affects the long-term prognosis of patients and the quality of life. Autologous mucosal grafts have proven to be successful in preventing stricture after ESD for early esophageal cancer.

Evaluation of net carbon sequestration and ecological benefits from single biochar-incorporated sorghum farmland systems in saline-alkali areas of Inner Mongolia, China.

Biochar is widely recognized as a soil amendment to reduce greenhouse gas emissions and enhance soil carbon storage in agroecosystems; however, the systematic focus on carbon balance and ecological benefits in cropping systems remains unclear in saline-alkali areas under water-saving irrigation. Here, a 2-yr field experiment with carbon footprint method was conducted to determine soil carbon budgets, biochar carbon efficiency performance, and the economic and ecological benefits of mulched drip-irrigated sorghum production, in an arid salinized region of Inner Mongolia, China. Corn straw-derived biochar dosages of 0 (CK), 15 (B15), 30 (B30), and 45 (B45) t hm were just applied into the soil in the first crop growing season.

Dynamic network link prediction with node representation learning from graph convolutional networks.

Dynamic network link prediction is extensively applicable in various scenarios, and it has progressively emerged as a focal point in data mining research. The comprehensive and accurate extraction of node information, as well as a deeper understanding of the temporal evolution pattern, are particularly crucial in the investigation of link prediction in dynamic networks. To address this issue, this paper introduces a node representation learning framework based on Graph Convolutional Networks (GCN), referred to as GCN_MA.

Enhanced Absolute Recovered Energy under Low Electric Field in All-Inorganic 0-3 Nanocomposition Thick Films.

Inorganic thick-film dielectric capacitors with ultrahigh absolute recovered energy at low electric fields are extremely desired for their wide application in pulsed power systems. However, a long-standing technological bottleneck exists between high absolute energy and large recovered energy density. A new strategy is offered to fabricate selected all-inorganic 0-3 composite thick films up to 10 µm by a modified sol-slurry method.

An empirical study on the effect of outdoor illumination and exercise intervention on Children's vision.

Objective: To explore the relationship between outdoor lighting and sports and the development of myopia, and to analyze the effects of outdoor lighting and exercise on the diopter of children with normal vision and myopia, so as to provide guidance for the prevention and treatment of myopia in children and adolescents in the future.

Methods: A total of 201 children were divided into two groups according to myopia or not. Each group was randomly divided into 4 groups: outdoor exercise group, outdoor control group, indoor exercise group and indoor control group.

Molecular Simulation of Thermodynamic Properties of CH/CO Adsorption by Coal Molecules at Different Temperatures and Moisture Contents under Variable Pressure Conditions.

In order to further elucidate the thermodynamic mechanism of CH/CO adsorption by coal molecules, the adsorption behavior of a molecular model of coal (CHON) at Wucaiwan, Zhundong was investigated by applying Materials Studio 2020 and Monte Carlo (GCMC) simulation methods, and the adsorption behavior of CH and CO was studied from the thermodynamic point of view under the conditions of different temperatures, pressures, and moisture contents. The results showed that at different temperatures or moisture contents, CH molecules had a low-density scattering distribution and CO molecules had a high-density polymerization distribution. Temperature and moisture content and adsorption constants a and b were negatively correlated.

Electroencephalography microstates as novel functional biomarkers for insomnia disorder.

Background: Insomnia disorder (ID) is one of the most common mental disorders. Research on ID focuses on exploring its mechanism of disease, novel treatments and treatment outcome prediction. An emerging technique in this field is the use of electroencephalography (EEG) microstates, which offer a new method of EEG feature extraction that incorporates information from both temporal and spatial dimensions.