2 results match your criteria: "Inner Mongolia University for Nationalities Affiliated Hospital[Affiliation]"
In Vitro and Vivo Experiments Revealing Astragalin Inhibited Lung Adenocarcinoma Development via LINC00582/miR-140-3P/PDPK1.
J Biochem Mol Toxicol
December 2024
Department of Pathology, Inner Mongolia University for Nationalities Affiliated Hospital, Tongliao, China.
Article Synopsis
- This study investigated how astragalin affects the development of lung adenocarcinoma (LUAD) by analyzing gene profiles and using bioinformatics to identify a novel lncRNA-mediated miRNA/mRNA interaction.
- Experimental cell studies showed that the lncRNA LINC00852 plays a key role in LUAD by influencing cell behaviors like growth and migration, while specific techniques like siRNA were used to demonstrate effects on proliferation and apoptosis.
- The research indicated that targeting the LINC00582/miR-140-3p/PDPK1 pathway represents a promising therapeutic approach for LUAD treatment, highlighting its potential as a novel drug target for astragalin.
Prevalence of human papillomavirus in archival head and neck cancer in the eastern Inner Mongolian Autonomous Region, China.
Tumori
October 2020
Biotherapy Center, The Seventh Medical Center of PLA General Hospital, Beijing, China.
Objective: To investigate the prevalence of human papillomavirus (HPV) in archival head and neck cancer (HNC) collected from the Tong-Liao area, which is located in east Inner Mongolia, China.
Methods: The presence of HPV in 54 HNCs and 25 benign biopsies was detected and the sequence variation of the E6 gene in HPV-positive samples was analyzed to determine their lineage/sublineage classification.
Results: HPV was detected in only 4 out of 54 HNCs and no benign biopsies were found to be HPV-positive.