2 results match your criteria: "Inner Mongolia Chifeng Hospital[Affiliation]"
Gene polymorphism of DNA repair gene X-ray repair cross complementing group 1 and xeroderma pigmentosum group D and environment interaction in non-small-cell lung cancer for Chinese nonsmoking female patients.
Kaohsiung J Med Sci
January 2019
Department of Medical Oncology in Section One, Inner Mongolia Chifeng Hospital, Chifeng, China.
Article Synopsis
- A study found a link between genetic variations in repair genes XRCC1 and XPD and the risk of non-small-cell lung cancer (NSCLC) in nonsmoking female patients from the East Chinese Han population.
- Researchers analyzed DNA samples from 327 NSCLC patients and 342 controls, discovering that certain genetic polymorphisms and exposure to cooking oil mist and soot were more common in patients with NSCLC.
- The findings suggest that both genetic factors and environmental exposures may work together to increase the likelihood of developing NSCLC in the target demographic.
microRNA-145-3p inhibits non-small cell lung cancer cell migration and invasion by targeting PDK1 via the mTOR signaling pathway.
J Cell Biochem
January 2018
Department of Medical Oncology in Section One, Inner Mongolia Chifeng Hospital, Chifeng, P. R. China.
The mammalian target of rapamycin (mTOR) pathway is dysregulated in more than 50% of all human malignancies and is a major target in cancer treatment. In this study, we explored the underlying mechanism involving microRNA-145-3p (miR-145-3p) in the development and progression of non-small cell lung cancer (NSCLC) by targeting PDK1 via the mTOR signaling pathway. NSCLC tissues and adjacent normal tissues were obtained from 83 NSCLC patients.
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