1,357 results match your criteria: "Inner Ear Sudden Hearing Loss"

Introduction: This report describes the outcomes of sensorineural hearing loss (SNHL) due to cochlear inner ear barotrauma (IEBt) in five divers treated with hyperbaric oxygen (HBOT).

Methods: The case histories of five consecutive divers presenting with SNHL from IEBt due to diving, were reviewed. All divers provided written consent for their data to be included in the study.

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Introduction: Sudden sensorineural hearing loss (SSNHL) is idiopathic in 70-90% of cases with 10-30% linked to vascular injuries, viral infections, or autoimmune inner ear disease (AIED). AIED contributes to less than 1% of all hearing losses, categorized into primary, affecting only the inner ear, and secondary, associated with systemic autoimmune diseases (SAID). This study examines the prevalence and features of AIED in SSNHL in a tertiary referral center.

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Window Coverage and Liquid Biopsy in the First-Line Therapy of Severe Sudden Sensorineural Hearing Loss.

Brain Sci

November 2024

Department of Otolaryngology, Head and Neck Surgery, Campus Klinikum Bielefeld Mitte, Medical School OWL, Bielefeld University, Teutoburger Str. 50, 33604 Bielefeld, Germany.

Introduction: Based on clinical practice guidelines, the application of corticosteroids as a first-line therapy is common. Although sudden sensorineural hearing loss (SSHL) etiology is primarily idiopathic, hearing loss can result from a perilymphatic fistula (PLF). Recent findings show evidence of a specific rate of PLF based on a cochlin-tomoprotein (CTP) detection test.

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Deep Phenotyping of a Mouse Model for Hearing Instability Disorders.

Otol Neurotol

December 2024

Auditory Development and Restoration Program, Neurotology Branch, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Bethesda, Maryland.

Article Synopsis
  • - The study examines hearing instability (HI) in Slc26a4-insufficient mice, suggesting that differences in ion homeostasis gene expression and activated macrophages may contribute to the disorder.
  • - Researchers conducted auditory tests and compared the results from mice with HI to those without, finding significant changes in gene expression and macrophage activity in the inner ear support cells of the affected mice.
  • - Findings indicate that these genetic and immune factors influence endolymphatic hydrops (EH) and endocochlear potential (EP), offering insights into HI's potential causes and its relevance to human health.
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Unveiling a Rare Phenomenon: Sudden Sensorineural Hearing Loss Following Skin Prick Testing.

Indian J Otolaryngol Head Neck Surg

October 2024

Department of Obstetrics and Gynecology, Government Medical College, Patiala, Punjab India.

Article Synopsis
  • The skin prick test (SPT) is used to diagnose allergies, and the case discusses an unusual incident where sudden sensorineural hearing loss (SSNHL) occurred after an SPT.
  • A 27-year-old man experienced hearing loss in one ear following the test, and audiometric tests confirmed SSNHL, which improved after corticosteroid treatment.
  • The case suggests a possible link between allergic reactions and SSNHL, highlighting the need for more research to understand this connection and explore treatment options.
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Hearing loss is the third leading cause of human disability. Age-related hearing loss, one type of acquired sensorineural hearing loss, is largely responsible for this escalating global health burden. Noise-induced, ototoxic, and idiopathic sudden sensorineural are other less common types of acquired hearing loss.

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Sudden Hearing Loss Waves: The Effect of COVID-19 Infection and Vaccination on the Inner Ear.

Adv Exp Med Biol

September 2024

Department of Otolaryngology-Head and Neck Surgery, University of California, Irvine, 333 City Blvd. West, Suite 525, Orange, CA, 92868, USA.

Article Synopsis
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Article Synopsis
  • - The study focuses on patients with incomplete partition type II (IP-II) malformation and large vestibular aqueduct (LVA), examining their hearing loss (HL) and the need for auditory rehabilitation (AR) solutions.
  • - Out of 55 patients, cochlear implants were used by 29.1%, hearing aids by 43.6%, and bimodal applications by 27.3%, with no significant differences found in dizziness, tinnitus, or HL progression.
  • - Findings show varied audiological characteristics in patients with IP-II and LVA, highlighting hearing aids as the most common AR method, but predicting the type of HL progression remains difficult and should be approached cautiously.
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Idiopathic sudden sensorineural hearing loss is an unexplained sudden loss of sensorineural hearing, with no specific pathogenesis, and is difficult to treat. The most common therapeutic strategy for idiopathic sudden sensorineural hearing loss is the use of steroids combined with neurotrophic drugs, as other treatments have shown limited efficacy. However, in recent years, hyperbaric oxygen therapy has emerged as a promising treatment option.

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MRI-Based Inner Ear Assessment and Cochlin Tomoprotein-Based Evaluation of Perilymphatic Fistula in Patients with Sudden Hearing Loss.

Brain Sci

July 2024

Department of Otolaryngology, Head and Neck Surgery, Medical Faculty OWL, Bielefeld University, Campus Klinikum Bielefeld, Teutoburgerstr. 50, 33604 Bielefeld, Germany.

Article Synopsis
  • This study aimed to investigate the relationship between cochlin tomoprotein testing (CTP), MRI findings, and hearing balance functions in patients experiencing sudden hearing loss.
  • Eight patients with sudden hearing loss and possible vertigo or tinnitus were examined using CTP testing through middle ear samples and various MRI techniques.
  • Results showed that while all patients exhibited non-specific contrast enhancement in the affected ear on MRI, only some had positive CTP tests indicating a potential perilymphatic fistula, but no MRI signals specifically indicated this condition.
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What should otolaryngologists know about dural venous sinus stenting?

Eur Arch Otorhinolaryngol

November 2024

Department of Neurosurgery Director, Brain and Spine Institute, Westchester Medical Center Health Network New York Medical College, 100 Woods Road, Macy Pavilion, 1331, Valhalla, NY, 10595, USA.

Article Synopsis
  • Dural venous sinus stenting is a growing procedure in otolaryngology that works in tandem with neurosurgeons and neuroradiologists, having been introduced around 20 years ago.
  • * It is now a standard treatment for patients experiencing increased intracranial pressure due to transverse sinus stenosis, with ENT doctors often being the first to diagnose these issues.
  • * Traditional treatments like high-dose diuretics were largely ineffective, and other methods have posed serious risks, making endovascular sinus stenting a promising option for patients with specific clinical and imaging characteristics.
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Purpose: To corroborate the vascular etiology of sudden sensorineural hearing loss (SNHL) utilizing magnetic resonance imaging (MRI).

Patient: A 24-year-old male with a history of sickle cell disease experienced sudden SNHL and right horizontal nystagmus, without accompanying vertigo.

Intervention: Audiometric evaluation revealed left-sided SNHL, predominantly affecting high frequencies.

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Objective: Hybrid of reversed image of positive endolymph signal and negative image of perilymph signal (HYDROPS) in delayed gadolinium-enhanced magnetic resonance imaging (MRI) typically depicts normal inner ear as "white-tone" and endolymphatic hydrops as "black-transparent" appearances, whereas ears with auditory and vestibular disorders are occasionally depicted as "gray-tone." This study aimed to investigate the pathological basis of sudden sensorineural hearing loss (SSNHL) patients with "gray-tone" appearances on HYDROPS.

Methods: Delayed gadolinium-enhanced MRI examinations were conducted on 29 subjects with unilateral SSNHL.

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Impact of audiovestibular factors on prognosis in patients with sudden sensorineural hearing loss without vertigo.

Eur Arch Otorhinolaryngol

November 2024

Department of Otorhinolaryngology - Head and Neck Surgery, Kaohsiung Veterans General Hospital, No.386, Dazhong 1st Rd., Zuoying Dist., Kaohsiung City, 813414, Taiwan (R.O.C.).

Article Synopsis
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Article Synopsis
  • Glucocorticoids (GC) are commonly used to treat various ear and sinus disorders, but many patients experience resistance to these treatments.
  • The exact mechanisms behind GC resistance are not well understood, leading to ongoing research in this area.
  • This paper reviews both GC receptor and non-receptor factors contributing to resistance, aiming to provide insights for developing alternative treatment options in the future.
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Potential Application of Hydrops MR Imaging: A Systematic Review.

J Otolaryngol Head Neck Surg

June 2024

Department of Otolaryngology, National Taiwan University Hospital, Taipei, Taiwan.

Article Synopsis
  • A diagnostic challenge exists between clinical Meniere's disease and radiological endolymphatic hydrops (EH) due to advancements in hydrops MRI technology aimed at improving EH diagnosis.
  • Over 470 articles were reviewed, leading to the selection of 80 that showed variability in sensitivity (69%-92%) and specificity (78%-96%) for detecting EH, likely influenced by candidate selection and grading systems.
  • The study suggests hydrops MRI can distinguish EH from other conditions, identify the affected ear, and confirm EH in conjunction with other disorders, but highlights limitations in visualizing certain inner ear issues where improved imaging technology is necessary.
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Idiopathic sudden sensorineural hearing loss: A review focused on the contribution of vascular pathologies.

Auris Nasus Larynx

August 2024

Department of Otolaryngology, Head and Neck Surgery, Tokai University School of Medicine, 143 Shimokasuya, Isehara-city, Kanagawa 259-1193, Japan. Electronic address:

Article Synopsis
  • Idiopathic sudden sensorineural hearing loss (ISSNHL) is a quick-onset hearing loss that may come with vertigo, often linked to vascular issues like cochlear ischemia or infarction.
  • The labyrinthine artery is crucial for blood supply to the inner ear, and its occlusion can lead to sudden hearing loss, requiring MRI and brainstem response tests for accurate diagnosis.
  • Factors like a high risk of stroke (CHADS score), cardiovascular issues, and certain blood markers may indicate a worse prognosis for patients with ISSNHL.
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<b><br>Introduction:</b> Idiopathic sensorineural hearing loss of 30 decibels (dB) or more over at least three contiguous audiometric frequencies with an onset of less than 3 days is referred to as sudden sensorineural hearing loss (ISSNHL) and is known as an ENT (ear, nose, and throat) emergency. When a patient's hearing suddenly deteriorates, they become confused, anxious, and worried. One of the primary therapies for sudden sensorineural hearing loss is intratympanic steroids.

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Sound Exposure Promotes Intratympanic Drug Delivery to the Inner Ear.

Otolaryngol Head Neck Surg

October 2024

Department of Otolaryngology-Head and Neck Surgery, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.

Objective: To investigate the impact of sound exposure, with the resultant windows vibration on perilymphatic concentrations following intratympanic (IT) dexamethasone and gentamicin in an animal model.

Study Design: Animal model blinded study.

Setting: Animal facility of a tertiary medical center.

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A 61-year-old man with right hearing loss and staggering for seven months was diagnosed with sudden deafness although previous evaluation with MRI indicated minor abnormal findings. During follow-up, he developed hypogeusia, right facial nerve palsy, pain in right mandible, right-sided temporal pain, and cerebellar ataxia. Cerebrospinal fluid examination at admission revealed reduced glucose concentration and elevated soluble interleukin-2 receptor (sIL-2R) level, whereas serum sIL-2R level was within the normal range.

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