Investigations of thermoluminescence characteristics of CaSiO:Yb phosphor irradiated with gamma rays and carbon ion beam.

In the present work, the thermoluminescence (TL) properties of Yb doped CaSiO phosphor exposed to gamma rays and carbon (C) ion beam have been reported. The phosphor has been synthesized using solid-state reaction method. The formation and surface morphology of the phosphor have been studied using X-ray diffraction (XRD) and field emission scanning electron microscopy (FE-SEM) respectively.

Isolation, Characterization, and In Silico Interaction Studies of Bioactive Compounds from Caesalpinia bonducella with Target Proteins Involved in Alzheimer's Disease.

Alzheimer's disease (AD) is a multifactorial neurodegenerative disorder characterized by memory loss, cognitive deterioration, and neuropsychiatric symptoms. Various drug targets implicated in AD are amyloid beta peptides, cholinesterase enzymes, and anti-amylogenic protein. Medicinal plants derived phytochemical constituents provide a vast pool of diverse compounds as a source of novel drugs.

A Blockchain Framework to Secure Personal Health Record (PHR) in IBM Cloud-Based Data Lake.

The health system in today's real world is significant but difficult and overcrowded. These hurdles can be diminished using improved health record management and blockchain technology. These technologies can handle medical data to provide security by monitoring and maintaining patient records.

Accuracy of assessing 18, 21, and 25 years of age using Olze et al. stage-based system in an Indian sample of young adults.

Background: Recently, Olze et al. came up with a staging system based on the radiological changes in the root pulp of the third molar.

Aims & Objectives: The current study seeks to ascertain the utility of visibility of the root pulp of the third molar as a system of forensic age estimation in the Indian population, as suggested by Olze.

Hybridized wavelet neuronal learning-based modelling to predict COVID-19 effects in India and USA.

Coronavirus disease so called as COVID-19 is an infectious disease and its spread takes place due to human interaction by their pathogen materials during coughing and sneezing. COVID-19 is basically a respiratory disease as evidence proved that a large number of infected people died due to short breathing. Most widely and uncontrollably spreading unknown viral genome infecting people worldwide was announced to be 2019-2020 by WHO on January 30, 2020.

Fabrication of alkoxysilane substituted polymer-modified disposable biosensing platform: Towards sperm protein 17 sensing as a new cancer biomarker.

SP17 is a mammalian protein found in the testis and spermatozoa that have been identified as a tumor-associated antigen in a range of human cancers. A unique method for fabricating the first ultrasensitive, selective, and label-free immunosensor for the detection of SP17, a new cancer biomarker in complicated serum samples, is presented in this paper. This immunosensor was also the first biosensor built using a disposable ITO sheet modified with an aminosilane known as APTMS as an immobilization platform for fabricating the SP17 biosensor.

Hindi translation and reliability testing of the international spinal cord injury quality of life basic data set version 1.0.

Study Design: Methodological study design: translation and test-retest reliability testing.

Objectives: To translate International Spinal Cord Injury Quality of Life Basic Data Set (ISCIQoLBDS) Version 1.0 into Hindi language and conduct reliability testing of Hindi ISCIQoLBDS (hISCIQoLBDS).

Determinants of socio-demographic and environmental barriers in prevention of COVID-19 pandemic.

Aim And Objectives: This study assessed the knowledge, attitude, and practice of patients with ESIC, who are insured patients with the public health sector about COVID-19.

Materials And Method: This was a cross-sectional observational study that used a questionnaire developed for the purpose of the survey. The questionnaire was divided into five parts including the demographic variables and environmental variables that are enablers for positive preventive practices of COVID-19, knowledge, attitude, and preventive practices followed with respect to COVID-19.

Morphometric and Microsatellite Diversity in Seabuckthorn ( L.) Natural Populations Originating from the Different Geographical Regions of the Indian Himalayas.

Unlabelled: Seabuckthorn ( L.), an upcoming superfood plant, has attracted researchers' attention worldwide for its medicinal, nutritional, and socio-economic value, along with its characteristic features to sustain extreme climatic conditions. We have studied microsatellite marker-based genetic and morphometric diversity in 93 collections of from different geographic sites representing two regions, namely Leh and Lahaul of the Indian Himalayas.

Ameliorations in dyslipidemia and atherosclerotic plaque by the inhibition of HMG-CoA reductase and antioxidant potential of phytoconstituents of an aqueous seed extract of Acacia senegal (L.) Willd in rabbits.

The assigned work was aimed to examine the capability of phytoconstituents of an aqueous seed extract of Acacia senegal (L.) Willd to inhibit HMG-CoA reductase and regression of the atherosclerotic plaque. The chemical fingerprinting of the test extract was assessed by LC-MS/MS.

Distribution of simple sequence repeats, transcription factors, and differentially expressed genes in the NGS-based transcriptome of male and female seabuckthorn ().

Seabuckthorn () is a perennial, multipurpose wonder plant, popular for its immense medicinal, nutritional, and therapeutic properties. However, due to the lack of whole-genome-based studies, the molecular mechanism governing distinct sexual phenotypes is still not clear. We employed the high-throughput NGS Illumina NovaSeq paired-end technology to generate whole transcriptome profiles of male and female plants of .

Nitrate-responsive transcriptome analysis reveals additional genes/processes and associated traits viz. height, tillering, heading date, stomatal density and yield in japonica rice.

Our transcriptomic analysis expanded the repertoire of nitrate-responsive genes/processes in rice and revealed their phenotypic association with root/shoot, stomata, tiller, panicle/flowering and yield, with agronomic implications for nitrogen use efficiency. Nitrogen use efficiency (NUE) is a multigenic quantitative trait, involving many N-responsive genes/processes that are yet to be fully characterized. Microarray analysis of early nitrate response in excised leaves of japonica rice revealed 6688 differentially expressed genes (DEGs), including 2640 hitherto unreported across multiple functional categories.

Determination of Tripartite Interaction between Two Monomers of a MADS-box Transcription Factor and a Calcium Sensor Protein by BiFC-FRET-FLIM Assay.

Protein-protein interactions are an integral part of all biological processes in the cells as they play a crucial role in regulating, maintaining, and amending cellular functions. These interactions are involved in a wide range of phenomena such as signal transduction, pathogen response, cell-cell interactions, metabolic and developmental processes. In the case of transcription factors, these interactions may lead to oligomerization of subunits, sequestering in specific subcellular contexts such as the nucleus, cytoplasm, etc.

COVID-19 lockdown and environmental pollution: an Indian multi-state investigation.

Originating from China, COVID-19 became the first-ever coronavirus pandemic, wreaking havoc in 218 nations. The lack of a potential treatment exacerbated by the inability of the healthcare infrastructure to contain the viral trajectory led to a worldwide lockdown. The anthropogenic halt presented an unprecedented background to quantify the effect of the anthroposphere on environmental pollution.

Comprehensive study on impact assessment of lockdown on overall ambient air quality amid COVID-19 in Delhi and its NCR, India.

Indian government announced the complete lockdown from 25 March, 2020 for all outdoor activities across the country due to containment of COVID-19. This study is an attempt to assess the impacts of lockdown on ambient air quality in five cities of Indian National Capital Region including Delhi, Gurugram, Noida, Ghaziabad and Faridabad. In this context, the data of air pollutants (PM, PM, NOx, NO, NO, SO, NH, SO, CO, and CH) from 36 locations of the study area were analyzed from 1 March to 1 May, 2020.

Lipid Nanocarriers for Neurotherapeutics: Introduction, Challenges, Blood-brain Barrier, and Promises of Delivery Approaches.

Significant efforts have been made in research to discover newer neurotherapeutics, however, the rate of reported neurological disorders has been increasing at an alarming speed. Neurotherapeutics delivery in the brain is still posing a significant challenge, owing to the blood-brain barrier and blood-cerebrospinal fluid barrier. These physiological barriers restrict the passage of systemically available fractions of neurotherapeutics into the brain, owing to low permeability and drug localization factors.

Tumour suppressor role of microRNA-335-5p in esophageal squamous cell carcinoma by targeting TTK (Mps1).

Background: Esophageal cancer is an aggressive malignancy. miR-335-5p is reported to possess both tumour suppressor and tumour promoter activities in different cancers.

Objectives: We investigated the role of miR-335-5p in esophageal cancer by expression and functional studies.

Investigating the key role of carrier transport mechanism in SnSe nanoflakes with enhanced thermoelectric power factor.

A novel SnSe nanoflake system is explored for its thermoelectric properties from both experiments andstudy. The nanoflakes of the low temperature phase of SnSe (Pnma) are synthesized employing a fast and efficient refluxing method followed by spark plasma sintering at two different temperatures. We report an enhanced power factor (12-67W mKin the temperature range 300-600 K) in our p-type samples.

Spatio-temporal assessment on land use and land cover (LULC) and forest fragmentation in shifting agroecosystem landscape in Ukhrul district of Manipur, Northeast India.

The information on land use and land cover (LULC) plays a critical role in understanding the interactions between human activities and the natural environment. The changes in LULC have a significant impact on the ecological integrity of forests, biodiversity, and natural resources, which in turn trigger global environmental change. Forest fragmentation is an important conservation challenge that includes interdependent forest loss components and spatial shift patterns.

Enhanced adsorption of metal ions onto Vetiveria zizanioides biochar via batch and fixed bed studies.

The study highlights the potential of Vetiveria Zizanioides derived biochar for heavy metal removal in multicomponent systems. Biochar efficiency varies with pH, metal ion concentration and residence time. Maximum removal efficiency was found to be 66.

Identification of stage-specific differentially expressed genes and SNPs in gastric cancer employing RNA-Seq based transcriptome profiling.

We analysed over 400 million reads obtained from Illumina sequencing of six pairs of libraries representing two each of stage I, II, and III gastric tumors and corresponding normal tissues to identify differentially expressed genes (DEGs), single nucleotide polymorphisms (SNPs), and transcription factors (TFs). In total, 2207 DEGs including 972 upregulated genes and 1235 downregulated genes were detected. Of these, several stage-specific signature genes were identified.

Sequence, structural and functional conservation among the human and fission yeast ELL and EAF transcription elongation factors.

Background: Transcription elongation is a dynamic and tightly regulated step of gene expression in eukaryotic cells. Eleven nineteen Lysine rich Leukemia (ELL) and ELL Associated Factors (EAF) family of conserved proteins are required for efficient RNA polymerase II-mediated transcription elongation. Orthologs of these proteins have been identified in different organisms, including fission yeast and humans.

RETRACTED ARTICLE: A cognitive approach for blockchain-based cryptographic curve hash signature (BC-CCHS) technique to secure healthcare data in Data Lake.

[This retracts the article DOI: 10.1007/s00500-021-06513-7.].

Simultaneous removal of organic and inorganic pollutants from water by Ni/NiO/SnO nanoparticles.

Herein, we report a facile synthesis of Ni/NiO/SnO hybrids where the core-shell-type Ni/NiO nanoparticle is decorated with the SnO nanoparticle to make a heterojunction and their potential evaluation for simultaneous removal of organic and inorganic pollutants. The metallic nickel core of the nanoparticle helps to separate easily from water magnetically and restricts the possible secondary contamination. The formation of semiconductor-semiconductor heterojunction enhances the photocatalytic activity to degrade the organic pollutants.