Mortality and functional outcomes in elderly adults treated surgically by hemiarthroplasty for femoral neck fractures.

Background: Despite multiple studies, less recent literature and data regarding the mortality associated with hip fractures in the elderly population are available.

Objectives: To assess the mortality data and functional outcomes of patients who underwent cemented and uncemented hemiarthroplasty in femoral neck fractures. To evaluate if preoperative (minimum 2 months) calcium and vitamin D supplement intake in patients affects postoperative mobilization with or without walker support.

screening of dicoumarols as potential enzyme inhibitors in : molecular docking, ADME, QSAR and MD simulations.

UDP-N-acetylenolpyruvoylglucosamine reductase ( from has gathered significant pharmaceutical interest as a pivotal target because of its essential role in bacterial viability. This study employed computational methods to screen and assess the inhibitory potential of dicoumarol derivatives against the protein. A diverse set of dicoumarols, sourced from PubChem and Zinc database, is subjected to molecular docking, ADME studies, and MD simulations to elucidate interacting modes and stability.

Unraveling the impact of abiotic stress on conserved microRNA expression and their target genes in .

Unlabelled: Production of stevioside and rebaudioside in is greatly affected due to extreme environmental conditions. MicroRNAs are known to play an important role in post-transcriptional gene regulation. Here, the aim was to study the effect of abiotic stresses on the plantlets and then to identify and validate the expression of the conserved microRNAs and their targets under abiotic stress conditions.

Fault correcting adder design for low power applications.

Field Programmable Gate Arrays are extensively used in space, military, and commercial sectors due to their reprogrammable nature. In high-safety environments, ensuring fault tolerance is crucial to improving the performance of electronic and computational systems. Common fault-tolerant methods include time redundancy, double modular redundancy, triple modular redundancy, hardware redundancy, self-checking, self-repairing, and Operand Width Aware Hardware Reuse.

Spatio-temporal analysis of urban forest fragmentation in Delhi, India, using Landscape Fragmentation Tool v2.0.

Remote sensing (RS) has been widely used to assess the forest health status. Forest fragmentation has been recognized as a threat to the forest as it causes loss of biodiversity. The study of forest fragmentation is important for the conservative approach to forest area.

Smart polymers: key to targeted therapeutic interventions.

Smart polymers represent a class of advanced materials that undergo reversible changes in their physical or chemical form and are known as responsive polymers. These polymers show transitions when external stimuli, such as temperature and pH, come into play. Smart polymers are being increasingly applied in various fields, such as drug delivery to a targeted site and gene therapy.

Biological treatment of methyl orange dye and textile wastewater using halo-alkaliphilic bacteria under highly alkaline conditions.

As the textile wastewater is highly saline and has high pH it is important to employ extremophilic microbes to survive in harsh conditions and provide effective bioremediation of textile dyes. This study aims to find a sustainable solution for dye removal by investigating the potential of an indigenously isolated bacterium, Nesterenkonia lacusekhoensis EMLA3 (halo-alkaliphilic) for treatment of an azo dye, methyl orange (MO) and textile effluent. MO dye decolorization studies were conducted using mineral salt media (MSM) by varying incubation time (0-120 h), initial dye concentration (50-350 mg/L), pH (7.

Effects of Silver Nanoparticles on Ctenopharyngodon idella: Synthesis, Characterization, Antibacterial Activity, and Toxicological Assessment.

Currently, nanotechnology (NT) and nanoparticles (NPs) have gained significant attention in the scientific field due to their diverse application history. Particularly, in environmental applications, their antibacterial efficiency in fisheries due to antibacterial resistance. However, the NPs have been found toxic in the environment.

Revisiting the GBB reaction and redefining its relevance in medicinal chemistry: A review.

Multicomponent reactions (MCRs) have significant relevance in the field of synthetic chemistry, and in recent times one of the MCR variants, named the Groebke-Blackburn-Bienaymé (GBB) reaction, has attracted massive attention for the synthesis of biologically important scaffolds. The present review elaborates on the chemical advancement reported for the GBB reaction with an emphasis on the role of various catalytic systems. Further, the role of the GBB reaction has been redefined as a standard protocol for the synthesis of an array of potential bioactive compounds.

Inclusion complexes of novel formyl chromone Schiff bases with β-Cyclodextrin: Synthesis, characterization, DNA binding studies and in-vitro release study.

The present study involved the synthesis of five novel Schiff bases (SB1-SB5) of formyl chromone and their inclusion complexes with β-cyclodextrin through kneading approach to enhance the solubility and stability of SBs. Characterization was conducted using FTIR, NMR, SEM, TEM, p-XRD, and Mass Spectrometry. UV fluorescence and pH stability studies confirmed the formation of the inclusion complex.

GC-MS analysis, molecular docking, and pharmacokinetic studies on Dalbergia sissoo barks extracts for compounds with anti-diabetic potential.

Diabetes is a metabolic condition defined by abnormal blood sugar levels. Targeting starch-hydrolyzing enzymes and Dipeptidyl Peptidase 4 (DPP-4) expressed on the surface of numerous cells is one of the key strategies to lower the risk of Type-2 diabetes mellitus (T2DM). Dalbergia sissoo Roxb.

Measurement and performance evaluation of triple band differential integrated extraoral rectifying antenna for data transfer and RF energy harvesting for tongue drive system.

Wearable assistive devices are vitally important for tetraplegic individuals to provide valuable insights into their intended directives tailored to tongue motions in wireless healthcare industries. The flexible differentially driven extraoral antenna and rectenna measurement system are developed to enable differential sensing and monitoring of the set of unique tongue gestures for extraoral tongue drive system (eTDS) applications in three frequency bands of Industrial, Scientific, and Medical (ISM) (915.0 MHz, 2400 MHz, and 5800 MHz).

Small Molecule Assembly Agonist Alters the Dynamics of Hepatitis B Virus Core Protein Dimer and Capsid.

Chronic hepatitis B virus (HBV) poses a significant public health burden worldwide, encouraging the search for curative antivirals. One approach is capsid assembly modulators (CAMs), which are assembly agonists. CAMs lead to empty and defective capsids, inhibiting the formation of new viruses, and can also lead to defects in the release of the viral genome, inhibiting new infections.

Effect of anisotropy and length dispersity on electrical and optical properties of nanowire network based transparent electrodes: a computational study.

We have studied the impact of nanowire alignment and measurement direction at the percolation threshold on the effective resistance () of two-dimensional (2D) films. This helps us to analyze the effect of anisotropy on the conductivity and transmittance of the nanowire-based network characterized by the disorder parameter (). These optoelectronic properties are determined for systems with monodisperse and bimodal length distribution (a combination of two fixed lengths of nanowires).

Phenotypic, Physiological, and Gene Expression Analysis for Nitrogen and Phosphorus Use Efficienies in Three Popular Genotypes of Rice ( Indica).

Crop nitrogen (N) and phosphorus (P) use efficiencies (NUE/PUE) are important to minimize wastage and nutrient pollution, but no improved crop for both is currently available. We addressed them together in rice, in the view of its high consumption of NPK fertilizers. We analyzed 46 morphophysiological parameters for the N/P response in three popular indica genotypes, namely, BPT 5204, Panvel 1, and CR Dhan 301 at low, medium, and normal N/P doses.

Microplastics in ecosystems: Critical review of occurrence, distribution, toxicity, fate, transport, and advances in experimental and computational studies in surface and subsurface water.

Microplastics (MPs), particles under 5 mm, pervade water, soil, sediment, and air due to increased plastic production and improper disposal, posing global environmental and health risks. Examining their distribution, quantities, fate, and transport is crucial for effective management. Several studies have explored MPs' sources, distribution, transport, and biological impacts, primarily focusing on the marine environment.

Optimized deep maxout for crowd anomaly detection: A hybrid optimization-based model.

Monitoring Surveillance video is really time-consuming, and the complexity of typical crowd behaviour in crowded situations makes this even more challenging. This has sparked a curiosity about computer vision-based anomaly detection. This study introduces a new crowd anomaly detection method with two main steps: Visual Attention Detection and Anomaly Detection.

Physiological Basis of Plant Growth Promotion in Rice by Rhizosphere and Endosphere Associated Streptomyces Isolates from India.

This study demonstrated the plant growth-promoting capabilities of native actinobacterial strains obtained from different regions of the rice plant, including the rhizosphere (FT1, FTSA2, FB2, and FH7) and endosphere (EB6). We delved into the molecular mechanisms underlying the beneficial effects of these plant-microbe interactions by conducting a transcriptional analysis of a select group of key genes involved in phytohormone pathways. Through in vitro screening for various plant growth-promoting (PGP) traits, all tested isolates exhibited positive traits for indole-3-acetic acid synthesis and siderophore production, with FT1 being the sole producer of hydrogen cyanide (HCN).

Effect of aerobic exercise program on neuropathic pain and quality of life in person with paraplegia: study protocol for a randomized controlled trial.

Background: Individuals with spinal cord injury (SCI) often suffer from neuropathic pain which is often disabling and negatively affects function, participation, and quality of life (QoL). Pharmacological treatments lack efficacy in neuropathic pain reduction hence studying alternatives to drug treatment is necessary. Preclinical evidence of various aerobic exercises has shown positive effects on neuropathic pain but scientific studies investigating its effect in the SCI human population are limited.