349 results match your criteria: "Indoor Aeroallergens"
Incorporating Aeroallergen Exposure Metrics into Clinical Asthma Care: A Pilot Study Using A Mixed-Methods Survey to Assess Aeroallergen Knowledge, Perceived Asthma Control, and Mitigation Strategies in Households of Children with Asthma.
Pediatr Allergy Immunol Pulmonol
December 2024
Department of Civil, Environmental, and Geodetic Engineering, The Ohio State University, Columbus, Ohio, USA.
Mitigation of household allergens is associated with the reduction of asthma exacerbations in those with allergic asthma and is recommended in recent asthma guidelines. However, we need to better understand patient knowledge of aeroallergens in their homes prior to integrating direct allergen measurement methods into standard asthma care. We conducted a mixed-methods sequential pilot study consisting of a survey and virtual interview with caregivers of children aged 3 to 15 with asthma diagnosis (any severity) about asthma control, household environment, mitigation knowledge and strategies, and knowledge of allergens and asthma.
View Article and Find Full Text PDFAllergic Rhinitis in Israel: A Multicenter Study of Allergic Rhinitis Across Three Climate Zones.
Isr Med Assoc J
November 2024
Allergy and Immunology Unit, Shaare Zedek Medical Center, Jerusalem, Israel, Faculty of Medicine, Hadassah-Hebrew University School of Medicine, Jerusalem, Israel.
Article Synopsis
- Allergic rhinitis (AR) affects 5% to 50% of the population worldwide, but specific studies on sensitization in Israeli patients have been limited.* -
- A study of 1,308 AR patients in Israel revealed an 86% overall positive skin prick test rate, with indoor allergens affecting 76% of participants; the most common allergens identified were mites, olive tree pollen, grass pollen, and cat dander.* -
- The findings can help allergists customize skin prick test panels and improve immunotherapy by focusing on the most prevalent aeroallergens in different climate zones.*
Allergen Sensitization and Its Association With Allergic Diseases in the Korean Population: Results From the 2019 Korea National Health and Nutrition Examination Survey.
Allergy Asthma Immunol Res
September 2024
Department of Internal Medicine, Chung-Ang University College of Medicine, Seoul, Korea.
Article Synopsis
- Allergens, like dust or pet dander, can make people allergic, and in Korea, about 45% of people are sensitized to them.
- The study tested over 2,300 people to see how allergic reactions relate to age and found different patterns for young people and older adults.
- People who are sensitized to allergens have higher chances of getting allergic conditions like skin rashes and sinus issues.
Clinical and molecular analysis of longitudinal rhinitis phenotypes in an urban birth cohort.
J Allergy Clin Immunol
September 2024
Department of Pediatrics, University of Wisconsin-Madison, Madison, Wis.
Article Synopsis
- Chronic rhinitis in children is linked to significant health issues and varies widely in symptoms, highlighting the need to define specific phenotypes for better treatment.
- The study tracked 485 urban children from ages 1 to 11 to identify patterns of rhinitis and their connections to early life factors, other allergies, and nasal cell gene expression.
- Four rhinitis phenotypes were found: low/minimal, persistent, persistent decreasing, and late increasing, with persistent symptoms associated with increased allergic sensitization and specific risk factors like frequent colds and antibiotic use.
Early life exposures of childhood asthma and allergies-an epidemiologic perspective.
Front Allergy
August 2024
College of Nursing and Health Sciences, Texas A&M University-Corpus Christi, Corpus Christi, TX, United States.
Article Synopsis
- Childhood asthma is a prevalent issue globally, characterized by symptoms like coughing, shortness of breath, and wheezing, which can result in missed school and hospital stays.
- Environmental factors, including air pollution and pollen, play a significant role in the development of asthma and allergies, particularly during the early years of life.
- Indoor microbial exposures, such as endotoxins and glucans, are also linked to allergic diseases in children, highlighting the importance of understanding these environmental influences for better asthma diagnosis and treatment.
Recent prevalence of allergic rhinitis caused by house dust mites among the pediatric population in Fukui, Japan.
World Allergy Organ J
July 2024
Department of Otorhinolaryngology, Head & Neck Surgery, Faculty of Medical Sciences, University of Fukui, Fukui, Japan.
Article Synopsis
- Allergic rhinitis (AR) caused by house dust mites (AR-HDM) is a common issue in children, and this study investigates its prevalence and characteristics in elementary students in Japan after the COVID-19 pandemic.
- A survey of 41,000 students revealed an AR-HDM prevalence of 18.8%, with many affected kids showing symptoms before starting school, and a significant number receiving treatment.
- Factors linked to a higher risk of developing AR-HDM include being male, being the first-born child, and having other allergic conditions like asthma and food allergies.
NPCC4: Climate change and New York City's health risk.
Ann N Y Acad Sci
September 2024
New York City Department of Health and Mental Hygiene, New York, New York, USA.
Article Synopsis
- This chapter from the NPCC4 report focuses on assessing climate health risks and resilience strategies in New York City, updating data since the last report in 2015.
- It highlights specific risks related to heat and flooding, and also addresses other health threats like air pollution, insect-borne illnesses, and water contamination.
- The report offers evidence-based strategies aimed at minimizing future climate-related health issues, especially in the context of concurrent public health crises like COVID-19.
Impact of the COVID-19 Pandemic on Cockroach Allergy: A 4-Year Retrospective Study.
Int Arch Allergy Immunol
November 2024
Division of Clinical Immunology and Allergy, Department of Internal Medicine, School of Medicine, Necmettin Erbakan University, Konya, Turkey.
Article Synopsis
- This study examined how sensitivity to cockroach (CR) allergens changed during the COVID-19 pandemic by comparing patients from the prepandemic and pandemic periods.
- Among 2,613 atopic patients, the prevalence of CR sensitivity increased from 8.6% to 12% during the pandemic, and individuals with CR sensitivity were also found to have a higher frequency of asthma.
- Additional findings showed that CR sensitivity was more common in older males and that those sensitive to CR also tended to have sensitivities to house dust mites (HDM) and dogs.
Bioaerosol Exposures and Respiratory Diseases in Cannabis Workers.
Curr Allergy Asthma Rep
July 2024
Department of Civil, Environmental, and Architectural Engineering, University of Colorado Boulder, Boulder, CO, 80309-0428, US.
Article Synopsis
- This review examines the risks linked to breathing in bioaerosols from indoor cannabis cultivation and production facilities.
- With the rise in indoor cannabis farming in the U.S., there are increasing reports of respiratory issues among workers, such as asthma.
- Preliminary findings suggest that airborne particles in these facilities include harmful fungi, bacteria, and plant material, which may endanger worker health, highlighting the need for more comprehensive research and safety measures in the industry.
Airborne indoor allergen serine proteases and their contribution to sensitisation and activation of innate immunity in allergic airway disease.
Eur Respir Rev
April 2024
School of Pharmacy, Queen's University Belfast, Belfast, UK
Article Synopsis
- Common airborne allergens, like pollen and animal dander, trigger type I allergic disorders in the respiratory system, leading to conditions such as allergic asthma and rhinitis.
- These allergens cause various immune responses, including IgE crosslinking and inflammatory cell infiltration, which can result in airway remodeling and dysfunction.
- The article reviews the role of serine proteases from allergens in promoting allergic reactions and suggests that small-molecule inhibitors might be a potential treatment strategy for allergic airway diseases.
Prevalence of aeroallergen sensitization in children in Northern China.
J Asthma
September 2024
Allergy Department, Children's Hospital Affiliated to Capital Institute of Pediatrics, Beijing, PR China.
Article Synopsis
- The study investigated sensitization rates to aeroallergens in children under 18, focusing on variations across age, sex, and disease.
- It included over 5,000 children, revealing that 67.8% were sensitized, with mold being predominant in younger children and weed pollen becoming more prevalent after age 4.
- Key risk factors for asthma identified were sensitization to mold, animal dander, and experiencing multiple sensitivities, indicating the need for careful monitoring in those affected.
Vitellin/Vitellogenin Is an Important Allergen in German Cockroach.
Int Arch Allergy Immunol
May 2024
Division of Bacterial, Parasitic, and Allergenic Products, Office of Vaccines Research and Review, Center for Biologics Evaluation and Research, US Food and Drug Administration, Silver Spring, Maryland, USA.
Article Synopsis
- German cockroach proteins Vg and Vn are linked to allergies like rhinitis and asthma, and this study successfully purified these proteins for further research on their allergenic properties.
- The purification process involved immunizing rabbits, creating specific IgG antibodies, and using advanced techniques to analyze the proteins for contamination and purity.
- Results showed that most allergic individuals (80%) had IgE antibodies specific to Vg/Vn, indicating these proteins play a significant role in GCr-related allergies.
Environmental exposure and sensitization patterns in a Swiss alpine pediatric cohort.
World Allergy Organ J
December 2023
Christine Kühne Center for Allergy Research and Education (CK-CARE), Davos, Switzerland.
Article Synopsis
- The study explored how environmental factors in a mountainous alpine region affect allergic sensitization in local school children.
- Despite the low levels of pollution overall, sensitization to allergens like grass and cats was found to be quite common among these children.
- Living near busy roads and having poor indoor conditions, such as visible mold, significantly increased the likelihood of developing allergies and related symptoms like asthma and rhinoconjunctivitis.
Aeroallergen sensitization patterns among patients with chronic rhinitis with or without concomitant asthma.
Braz J Otorhinolaryngol
April 2024
Universidade Federal da Bahia, Salvador, BA, Brazil.
Article Synopsis
- * A total of 1,066 adults were evaluated for asthma and chronic/allergic rhinitis using various methods including skin-prick tests and questionnaires, categorizing them into different groups based on their conditions.
- * Results showed that individuals with asthma had a significantly higher rate of allergen sensitization compared to those with chronic rhinitis alone, particularly with specific allergens like mites and cockroaches, indicating that asthma severity influences the sensitization profile.
Aeroallergens sensitization pattern in atopic patients in Qatar: A retrospective study.
Qatar Med J
November 2023
Adult Allergy and Immunology Section, Department of Medicine, Hamad Medical Corporation, Doha, Qatar. Email:
Article Synopsis
- - The study investigated the prevalence of aeroallergen sensitization in patients attending an Adult Allergy Clinic in Qatar, finding that 68% of the 554 patients tested were sensitized, with a high incidence of allergic rhinitis and asthma among them.
- - The most common allergens identified included house dust mites (Dermatophagoides pteronyssinus and Dermatophagoides farina), cat hair, and various cockroaches, with a significant number of patients sensitized to indoor allergens.
- - The results showed no significant gender differences in allergen sensitization, with many patients affected by multiple allergens, indicating a widespread issue with allergic respiratory diseases in the population studied.
A multi-city study of indoor air quality in green vs non-green low-income housing.
Environ Res
January 2024
Division of Environmental Health Science and Practice, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Article Synopsis
- - The study aimed to determine if homes built with "green" standards have lower levels of environmental contaminants, especially for low-income households, which are more vulnerable.
- - Conducted over a year in three U.S. cities, the study measured various contaminants, including black carbon, dust, and mold, using air and dust samples and resident reports.
- - Results indicated that green homes had significantly lower levels of black carbon, permethrin, and reported mold, suggesting that green building practices can reduce harmful environmental contaminants linked to health issues.
Environmental allergen reduction in asthma management: an overview.
Front Allergy
October 2023
Center for Molecular Biomedicine, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Vietnam.
Article Synopsis
- Asthma is a common disease affecting both kids and adults, with many struggling to control symptoms even while using medications.
- Allergic reactions to environmental allergens like dust mites, cockroaches, and molds are linked to severe asthma, but the types of allergens can vary by region.
- Avoiding these allergens is crucial for asthma management, as it may help reduce symptoms and the risk of asthma attacks; more research is needed to develop effective avoidance strategies.
Allergy to fungi: Advances in the understanding of fungal allergens.
Mol Immunol
November 2023
Inmunotek S. L, Spain.
Article Synopsis
- - Allergic diseases, including asthma, are on the rise globally, with allergies contributing significantly to asthma development in about 60% of adults and 80% of children.
- - Common allergens linked to asthma include pollens, mites, fungi, and animal dander, with fungi being a major cause of respiratory issues that can be severe and hard to avoid.
- - There's a lack of detailed knowledge about fungal allergens compared to other allergens, which is important for accurate diagnosis, predicting asthma flare-ups, and creating personalized treatment plans as environmental conditions change.
Fungi and bacteria in the beds of rural and urban infants correlate with later risk of atopic diseases.
Clin Exp Allergy
December 2023
COPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Gentofte, Denmark.
Article Synopsis
- Rural children experience lower rates of asthma and atopic diseases compared to urban children, raising questions about the protective role of indoor microbiota in non-farming rural homes.
- A study analyzed the fungi and bacteria in the beds of 514 six-month-old infants to determine their association with the later development of conditions like asthma, allergic rhinitis, and eczema by age six.
- Results indicated that infants from higher-risk groups (developing asthma and allergic rhinitis) had lower microbial diversity in their beds, while those developing eczema had higher fungal diversity, suggesting that bed dust microbes may play a significant role in influencing the risk of airway- and skin-related diseases based on living environments.
Allergic Rhinitis.
Pediatr Rev
October 2023
Rutgers-Robert Wood Johnson Medical School, New Brunswick, NJ.
Article Synopsis
- Allergic rhinitis (AR) is a common chronic disease affecting over 400 million people globally, with rising cases particularly among children, often starting before age 6.
- Many underserved and urban populations face underdiagnosis, leading to healthcare disparities and worsening outcomes, such as poor asthma control in untreated children.
- Treatment options for AR have expanded to include various medications, allergen immunotherapy, and biological therapies, and children with severe or persistent symptoms should be referred to allergists for comprehensive care.
Indoor aeroallergens from American cockroaches and mites initiate atopic march via cutaneous contact in a murine model.
PLoS One
July 2023
Department of Biology, National Changhua University of Education, Changhua, Taiwan.
Article Synopsis
- The "atopic march" refers to the progression of allergic diseases starting from childhood atopic dermatitis and potentially leading to conditions like asthma later in life.
- Researchers created a mouse model to study how skin exposure to allergens, specifically from cockroaches and dust mites, contributes to this progression.
- The findings indicate that skin sensitization to these allergens significantly increased allergy-related symptoms and immune responses in mice, suggesting that this model could help in developing new strategies for preventing or treating allergic diseases.
Going over Fungal Allergy: and Its Allergens.
J Fungi (Basel)
May 2023
Applied Science, Inmunotek S.L., Parque Científico Tecnológico Alcalá de Henares, 28805 Madrid, Spain.
Article Synopsis
- - Fungal allergies are a major contributor to respiratory issues, particularly worsening asthma, with specific fungi being more closely linked to allergic reactions and symptoms.
- - These allergens can be found both outdoors, mainly in warm and dry conditions, and indoors, particularly in poorly ventilated areas, leading to potential exposure in various environments.
- - The current methods for diagnosing fungal allergies are inconsistent and outdated, as they rely on a mix of allergenic sources that aren't well standardized, emphasizing the need for more precise, component-resolved diagnosis approaches.
Air Sampling and Analysis of Aeroallergens: Current and Future Approaches.
Curr Allergy Asthma Rep
May 2023
Division of Allergy/Immunology, University of Nebraska Medical Center, 68198, Omaha, NE, USA.
Article Synopsis
- - The review focuses on current air sampling instruments and methods for analyzing allergens, highlighting both conventional and innovative approaches.
- - Traditional spore trap sampling analyzed via microscopy is widely used but suffers from delays and requires skilled personnel, while newer methods like immunoassays and molecular biology are gaining traction.
- - Automated sampling devices are emerging that can classify pollen in real time using various technologies, but they're not yet ready to replace established allergen monitoring systems.
A review on aero-allergen induced allergy in India.
Clin Exp Allergy
July 2023
Ecology and Allergology Lab, Department of Zoology, The University of Burdwan, Bardhaman, West Bengal, India.
Article Synopsis
- Allergic diseases like asthma, rhinitis, and eczema are significant public health concerns in India, characterized by a high prevalence due to various environmental factors.
- The country has identified numerous allergenic sources, including 83 types of pollen and other fungi, dust mites, and insects, contributing to both indoor and outdoor allergic reactions.
- Ongoing research aims to enhance allergy diagnostics and treatments, while this review provides insights for clinicians on selecting appropriate tests and managing allergic patients based on regional specifics and genetic findings.