The ratio of COL2A1:COL1A1 in dartos tissue patients with hypospadias.

Background: The inelasticity of dartos tissue and the regulation of collagen expression are significant factors in the pathophysiology of chordee associated with hypospadias. While the COL2A1:COL1A1 ratio is recognised as a measure of cell differentiation, there is yet to be a study specifically examining this ratio in hypospadias. The aim of this study was to determine the COL2A1:COL1A1 ratio.

Probing the Molecular Mechanisms of Kratom's Antipsychotic Effects through a Multi-modal Computational Approach.

Background: Psychosis, marked by detachment from reality, includes symptoms like hallucinations and delusions. Traditional herbal remedies like kratom are gaining attention for psychiatric conditions. This was aimed at comprehending the molecular mechanisms of Kratom's antipsychotic effects utilizing a multi-modal computational approach.

Treadmill intervention attenuates motor deficit with 6-OHDA-induced Parkinson's disease rat via changes in lipid profiles in brain and muscle.

One of the key hallmarks of Parkinson's disease is the disruption of lipid homeostasis in the brain, which plays a critical role in neuronal membrane integrity and function. Understanding how treadmill training impacts lipid restructuring and its subsequent influence on motor function could provide a basis for developing targeted non-pharmacological interventions for individuals living with early stage of PD. This study aims to investigate the effects of a treadmill training intervention on motor deficits induced by 6-OHDA in rats model of PD.

Complex cesarean section: Surgical approach to reduce the risks of intraoperative complications and postpartum hemorrhage.

The incidence of cesarean section is dramatically increasing worldwide, whereas the training opportunities for obstetrician/gynecologists to manage complex cesarean section appear to be decreasing. This may be attributed to changing working hours directives and the increasing use of laparoscopy for gynecological surgical procedures, including in gynecological oncology. Various situations can create surgical difficulties during a cesarean section; however, two of the most frequent are complications from previous cesarean (myometrial defects, with or without placental intrusion and peritoneal adhesions) and the high risk of postpartum hemorrhage (uterine overdistension, abnormal placentation, uterine fibroids).

Two-Dimensional BiOCl Nanosheet-Encapsulated Cu2O Octahedra: p-n Junction Photocatalysts for Efficient Visible Light Driven CO2-to-CH4 Conversion.

Cu2O has attracted significant attention as a potential photocatalyst for CO2 reduction. However, its practical use is limited by rapid charge recombination, insufficient catalytic sites, and poor stability. In this study, we report a facile synthesis of Cu2O@BiOCl core-shell hybrids with well-defined shape of Cu2O and two-dimensional nanosheet structure of BiOCl.

Sources of HIV information and women's HIV knowledge in Southwest Sumba Indonesia: a cross-sectional study with mediation analysis.

Background: Despite multiple years of government HIV educational efforts, the growing trend of new cases among women in Indonesia runs parallel with their seemingly overall lack of comprehensive knowledge about HIV. A major prevention challenge for the Indonesian government lies in delivering HIV prevention education across the world's largest archipelago. This study investigates comprehensive HIV knowledge among reproductive-age women in Southwest Sumba, Indonesia, and the sources through which they report having learned about HIV along with potential mediators of the relationship between socioeconomic status (SES) and HIV knowledge.

Management of an isolated posterior cruciate ligament avulsion fracture in a pediatric patient using screw fixation: A case report.

Introduction: Isolated posterior cruciate ligament (PCL) avulsion fracture is rare in pediatric population. To our knowledge, there is no established guideline to treat this rare injury in children. This case highlights the diagnostic challenges and treatment strategies using screw fixation for such injuries, emphasizing the importance of timely intervention to prevent long-term complications.

A 5 year result of neglected posterior hip dislocation with unusual presentation of false acetabulum treat with skeletal traction followed by cemented total hip replacement: A case report.

Introduction And Importance: Neglected posterior hip dislocations in adults are rare, particularly when untreated for years. In developing nations, patients often rely on traditional bone setters, leading to delayed diagnosis and increased complications. Adult hip dislocations carry a higher risk of avascular necrosis and require complex treatments.

Primary bladder neck obstruction in females: Case series from the Indonesian population.

Introduction: Primary bladder neck obstruction (PBNO) is a rare but significant cause of BOO and LUTS in females, with unclear etiology involving theories of fibrotic narrowing, tissue hyperplasia, or muscle abnormalities. Due to nonspecific symptoms, PBNO diagnosis remains challenging, and optimal surgical treatment needs to be better defined.

Case Presentation: We report two cases of females in their 50s with recurrent urinary retention managed by indwelling catheters.

Bio-inspired chitosan/polydopamine-nanoparticle based sorbent bead: A versatile platform for separation and HPLC analysis of tetracycline antibiotics from various sample matrix.

This study introduces an innovative bio-based sorbent bead crafted by integrating chitosan (CS) biopolymers, Fe(NO3)3 and polydopamine nanoparticles (PDA NPs) via glutaraldehyde crosslinking. The primary focus of this study was the concurrent separation of diverse tetracycline antibiotics (TCs), followed by rigorous reversed-phase liquid chromatography analysis. The fabricated CS/Fe@PDA sorbent beads were comprehensively characterized using scanning electron microscopy and energy-dispersive X-ray spectroscopy, revealing a surface rich in active carbon (C), nitrogen (N), and oxygen (O) moieties.

Herbal nanoemulsions in cosmetic science: A comprehensive review of design, preparation, formulation, and characterization.

The rapid development of delivery systems for cosmetics has revealed two critical challenges in the field: enhancing the solubility of active ingredients and ensuring the stability of natural materials used in cosmetics. Nanoemulsion technology has emerged as an indispensable solution for addressing these challenges, not only enhancing the stability of cosmetics but also improving the solubility of pharmaceuticals and active ingredients with poor solubility. Nanoemulsion formulations have reinforced stability and amended the bioavailability of hydrophobic drugs.

Development and industrial application of geographical origin identification for Taiwanese oolong tea.

Taiwanese oolong tea is renowned for its excellent quality and enjoys a prestigious reputation both domestically and internationally. In recent years, there has been an issue with imported Taiwanese-style oolong tea being sold as genuine Taiwanese oolong tea, which has adversely affected the brand value of Taiwanese oolong tea. In this study, samples of domestic oolong tea (Taiwanese oolong tea) and Taiwanese-style oolong tea produced abroad (including China, Vietnam, Indonesia, Thailand, etc.

Risk factors for overtaking, rear-end, and door crashes involving bicycles in the United Kingdom: Revisited and reanalysed.

Background And Objective: Relevant research has provided valuable insights into risk factors for bicycle crashes at intersections. However, few studies have focused explicitly on three common types of bicycle crashes on road segments: overtaking, rear-end, and door crashes. This study aims to identify risk factors for overtaking, rear-end, and door crashes that occur on road segments.

Exploring data literacy self-perception among Indonesian high school students.

Data is becoming increasingly ubiquitous today, and data literacy has emerged an essential skill in the workplace. Therefore, it is necessary to equip high school students with data literacy skills in order to prepare them for further learning and future employment. In Indonesia, there is a growing shift towards integrating data literacy in the high school curriculum.

Investigation of alpha-glucosidase inhibition activity of Artabotrys sumatranus leaf extract using metabolomics, machine learning and molecular docking analysis.

One way to treat diabetes mellitus type II is by using α-glucosidase inhibitor, that will slow down the postprandial glucose intake. Metabolomics analysis of Artabotrys sumatranus leaf extract was used in this research to predict the active compounds as α-glucosidase inhibitors from this extract. Both multivariate statistical analysis and machine learning approaches were used to improve the confidence of the predictions.

Incorporating earned value management into income statements to improve project management profitability and elevate application in the business and management.

Our goal is to improve Project Management (PM) profitability and reduce discrepancies in information among stakeholders, which can result in conflicts. This will be accomplished by incorporating Earned Value Management (EVM) with the Income Statement and incorporating earnings before interest, tax, depreciation, and amortization (EBITDA) with the work breakdown structure (WBS). These incorporations will streamline information sharing between PM, other management professionals, and the stakeholders, ultimately fostering the application of PM within broader business and management contexts.

Balancing landscape values and tourism choices: Integrating participatory mapping and the IPBES Values Typology.

The United Nations Educational, Scientific and Cultural Organization (UNESCO) Biosphere Reserves aim to balance nature and human coexistence, but increasing tourism challenges landscape management. The Intergovernmental Science-Policy Platform on Biodiversity and Ecosystem Services (IPBES) stresses the importance of understanding stakeholder values for effective management of natural spaces through a typology of intrinsic, instrumental, and relational values. This study applies this IPBES typology to tourism preferences in the Archipelago Sea Biosphere Reserve (ABR) using Public Participation Geographic Information Systems (PPGIS).

Calcium Carbonate from Anadara granosa Shells Stimulates FGF2, TGF-β1, and Collagen Type 1 Expression in Rat Dental Pulp.

Objectives:  Calcium carbonate (CaCO), a major inorganic component in bones and teeth, offers potential protection against demineralization. This study investigates the effect of CaCO from shells on the expression of fibroblast growth factor 2 (FGF2), transforming growth factor-β1 (TGF-β1), and collagen type 1 in the rat dental pulp.

Materials And Methods:  The first maxillary molars of were perforated and subsequently pulp capped with CaCO extracted from shells.

Exploring the Changes in Mild Cognitive Impairment Blood-Based Biomarkers after Local Antibiotic Periodontal Treatment in Diabetic Patients: Secondary Analysis of Data from a Randomized Controlled Trial.

Objectives:  This article investigates the changes in blood-based biomarkers associated with mild cognitive impairment (MCI) risk in type 2 diabetic patients following local antibiotic periodontal treatment.

Materials And Methods:  A secondary analysis of data from a 24-week randomized controlled trial was conducted, involving 27 patients with type 2 diabetes mellitus and periodontitis. Participants received periodontal treatment biweekly from baseline until the 6th week of the study.

Denture Care Behavior and Lifespan of Removable Partial Dentures in Indonesian Military Personnel: An Approach Using the Theory of Planned Behavior.

Objectives:  In the context of military health, removable partial acrylic dentures (RPADs) are crucial for the quality of life and performance of Indonesian National Armed Forces (TNI) soldiers. Given the demanding and unpredictable military environment, RPADs provide a solution for soldiers experiencing tooth loss. This research aims to identify behavioral factors influencing the lifespan of RPADs among TNI soldiers.

Detection of Lip, Tongue, Masseter, and Temporalis Muscle Contractions with Electromyography Tools as an Early Diagnostic Medium for Dentoalveolar Malocclusion.

Objectives:  This study aims to detect early class I, II, and III malocclusions through the muscle strength of the lips, tongue, masseter, and temporalis.

Materials And Methods:  The study subjects were 30 pediatric patients with predetermined criteria. The subjects were divided into class I, II, and III malocclusions where each classification of malocclusion amounted to 10 people.

Factors Associated With Prelacteal Feeding of Commercial Milk Formula: An Analysis of Cohort Data From the BADUTA Study in Indonesia.

Introducing commercial milk formula (CMF) as prelacteal feeds can disturb exclusive breastfeeding and shorten breastfeeding duration. However, the prelacteal feeding of CMF has been growing alongside its increasing sales in Indonesia. This study examined predictors of the CMF feeding in the Malang and Sidoarjo districts of Indonesia.