Comparison of life expectancy determinants among gulf cooperation council members.

Background: Understanding the determinants of life expectancy (LE) is essential for effective policy planning and enhancing public health in the Gulf Cooperation Council (GCC) countries. This study aims to elucidate the complex interactions among sociodemographic (SD), macroeconomic (ME), and health resource (HR) factors that influence LE among the GCC countries.

Methods: We employed a Meta-Analytic Structural Equation Modeling to develop a comparative model across six GCC countries using annual data from 1990 to 2020.

Transcriptomics-based analysis of neurotoxic and reproductive effects in turbot (Scophthalmus maximus) after exposure to tris (2-chloroethyl) phosphate (TCEP).

Background: Tris (2-chloroethyl) phosphate (TCEP), a widely used flame retardant, is widespread in the environment and potentially harmful to organisms. However, the specific mechanisms of TCEP-induced neurological and reproductive toxicity in fish are largely unknown. Turbot (Scophthalmus maximus) is cultivated on a large scale, and the emergence of pollutants with endocrine disrupting effects seriously affects its economic benefits.

The first complete mitochondrial genome of Sumatran striped rabbit Nesolagus netscheri (Schlegel, 1880), and its phylogenetic relationship with other Leporidae.

Nesolagus netscheri, a Sumatran striped rabbit, is one of the rarest rabbits in the Leporidae family, and its genetic information is still limited. This study provides the first mitochondrial genome and molecular systematic characterization of the Sumatran striped rabbit, Nesolagus netscheri, Indonesia's rarest rabbit. It consists of a circular double-stranded DNA of 16,709 bp.

The Lived Experiences of Mothers Living with HIV in West Papua, Indonesia: A Qualitative Study.

Mothers living with human immunodeficiency virus (HIV) may experience adjustment issues due to their illness progression and the risk of intergenerational transmission of the disease. Existing research on women living with HIV has focused on how psychological transitions such as child care and breastfeeding influence maternal life, and how socioeconomic status, stigma, and social support impact psychological transitions. Little is known about the experiences of mothers living with HIV in Indonesia.

Linear Programming Optimization of Local Food-Based Recommendations for Undernourished Urban Poor Malaysian Children Aged 2 to 5 Years.

Background: Poor diet quality may contribute to undernutrition, particularly affecting young children from low-income households. Therefore, affordable and healthy local food-based recommendations (FBRs) are needed.

Objectives: This study aimed to (1) identify problem nutrient(s), (2) identify locally available nutrient-dense food sources that can provide adequate nutrients to meet the recommended dietary intakes of undernourished urban poor children aged 2-5 years, and (3) use linear programming to recommend a daily diet based on the current food patterns that achieves dietary adequacy and meets average food costs for these children.

Asiatic acid methyl ester, a new asiaticoside derivative, induces osteogenic differentiation of hPDLCs.

Objective: Asiaticoside has the capacity to induce osteogenic differentiation of human periodontal ligament cells (hPDLCs) through Wnt (Wingless-related integration site) signaling. A modified chemical structure (by removing glycoside side chain), referred to as asiatic acid methyl ester (AA1), has been constructed and evaluated for its capacity to induce osteogenic differentiation.

Design: hPDLCs viability was determined by MTT assay.

Osteoclastogenesis markers in craniofacial bone defects after demineralized dentin material membrane implantation as guided bone regeneration.

Unlabelled: Guided bone regeneration (GBR) is an alternative treatment for craniofacial bone defects reconstruction through membrane barrier adaptation, such as demineralized dentin material membrane (DDMM). DDMM is used as a substitute for GBR material, which aligns with Green Economy principles, it has a good biological osteoinductive and osteoconductive effects, and its structure resembles bones. The balance of bone remodeling when experiencing craniofacial defects will be altered and allow changes to resorption activity, so the mechanisms of osteoclastogenesis and bone resorption are vital.

Gynura procumbensin vitro adventitious root nanohydrogel improves inflammation-proliferation transition in second-degree burn healing.

Inflammation-proliferation transition plays a key role in the successful healing of a common burn type, second-degree burn. Gynura procumbens in vitro adventitious root nanohydrogel is currently being studied for its immunomodulatory to improve reparative environment. Root production and nanohydrogel preparation was done respectively by in vitro propagation and emulsion/ solvent diffusion with carbomer as a polymer.

Ultrasound renal denervation in hypertensive patients: A systematic review and meta-analysis.

Introduction: Hypertension is the leading noncommunicable disease case affecting 1.28 billion individuals worldwide, with most cases located in low- and middle-income countries. While there are numerous techniques for treating mild to moderate hypertension, properly controlling severe or resistant hypertension poses substantial challenges.

Formulation and evaluation of PVA-based composite hydrogels: physicochemical, leachables, and immunogenicity studies.

This study explores the formulation and characterization of poly(vinyl alcohol) (PVA)-based composite hydrogels synthesized through solid-state crosslinking. Comprehensive assessments were conducted on their physicochemical properties, leachables, and immunogenicity. Swelling experiments demonstrated that the incorporation of poly(vinylpyrrolidone) (PVP) enhanced water retention, while chitosan had a minimal effect on swelling behavior.

Right ventricular subclinical dysfunction in high-burden idiopathic outflow tract premature ventricular contraction population.

Background: The relationship between premature ventricular contractions (PVC) and right ventricular (RV) function is not widely known. Left ventricular (LV) dysfunction due to PVC is known as PVC-induced cardiomyopathy (PIC) and suppressing the PVC substrate would improve LV function. The effect of PVC ablation on changes in RV function in patients with subtle RV subclinical dysfunction remains unknown.

When the heart deceives: a case report of hyperthyroidism disguised as STEMI in female pregnant patient.

Background: Acute myocardial infarction during pregnancy is a rare condition with an incidence of 1 to 10 per 100,000 deliveries. ST-elevation myocardial infarction (STEMI) is dominating the clinical presentation. It is estimated that 29% of the patients had normal coronary arteries, and hyperthyroidism may be associated with coronary vasospasm.

Empathy and listening style among occupational therapists in Malaysia.

Introduction: As an occupational therapist, listening and empathy are critical components of practice because they are the foundation for developing therapeutic rapport with patients and their relatives. Currently, there is still no study regarding the level of empathy and listening styles among Occupational therapists in Malaysia. This study investigates the level of empathy and listening styles among occupational therapists in Malaysia and to examine their correlations.

Health educational intervention by school nurses to prevent children's helminthic infection in Bangladesh: A cluster non-randomized controlled trial.

Background: Helminthic infections are a major health burden worsened by inadequate health education and awareness among schoolchildren. This study aims to reduce helminthic infection by increasing awareness and knowledge through school nurse-led health education among primary schoolchildren in Bangladesh.

Materials And Methods: This was a prospective, open-label, parallel-group (1:1), cluster non-randomized controlled trial conducted on 5- to 12-year-old school-going children from September 2021 to September 2022 in rural Bangladesh.

The social support, healthy lifestyle, subjective well-being, and health-related quality of life among university students.

Background: The health-related quality of life and subjective well-being of young people need to be confirmed at the population level by identifying protective factors such as social support and their current healthy lifestyle. This study aims to examine a healthy lifestyle as a mediator of the associations between perceived social support to subjective well-being and health-related quality of life and also to analyze the associations between all these variables.

Methods And Materials: This study was conducted by cross-sectional survey of university students (N = 348) derived from ten cities/municipalities in East Kalimantan, Indonesia.

Characterization of Alpha Mangostin Loaded-Mesoporous Silica Nanoparticle and the Impact on Dissolution and Physical Stability.

Purpose: Improving drug solubility is crucial in formulating poorly water-soluble drugs, especially for oral administration. The incorporation of drugs into mesoporous silica nanoparticles (MSN) is widely used in the pharmaceutical industry to improve physical stability and solubility. Therefore, this study aimed to elucidate the mechanism of poorly water-soluble drugs within MSN, as well as evaluate the impact on the dissolution and physical stability.

Diagnostic challenges in differentiating mediastinal tuberculosis from mediastinal tumors: A case report.

Mediastinal tuberculosis poses significant diagnostic challenges due to its nonspecific clinical and radiological features, particularly in high TB incidence regions like Indonesia. Here, we present the case of A 17-year-old male, initially diagnosed with a mediastinal tumor, was later confirmed to have mediastinal tuberculosis (TB). Despite normal lab results, imaging revealed a right parahilar mass.

Bibliometric Analysis and ChatGPT-Assisted Identification of Key Strategies for Improving Primary Maternity Care Based on a Decade of Collective Research.

Maternity care within primary health facility settings is critical for reducing maternal and neonatal mortality in Indonesia. The aim of this study was to analyze research trends over the past decade to identify key strategies for improving maternity care in primary health care facilities in Indonesia. A bibliometric analysis was conducted using data from the Scopus database to map the research landscape and identify latent research topics in maternal health care.

The development of social attention in orangutans: Comparing peering behavior in wild and zoo-housed individuals.

Social learning plays an essential role in all cultural processes, but the factors underlying its evolution remain poorly understood. To understand how socio-ecological conditions affect social learning, we compared peering behavior (i.e.

Model description of combined numerical and stochastic groundwater flow in Bandung-Soreang Groundwater Basin, West Java, Indonesia.

The first groundwater modeling of the Bandung Aquifer Basin in 2009 used a finite difference method with a 0.5 km² grid, representing three volcanic geological layers. It assumed uniform hydraulic properties and used an equivalent homogeneous aquifer with anisotropic hydraulic conductivity.

Integrating and retrieving learning analytics data from heterogeneous platforms using ontology alignment: Graph-based approach.

This study explores the possibility of integrating and retrieving heterogenous data across platforms by using ontology graph databases to enhance educational insights and enabling advanced data-driven decision-making. Motivated by some of the well-known universities and other Higher Education Institutions ontology, this study improvises the existing entities and introduces new entities in order to tackle a new topic identified from the preliminary interview conducted in the study to cover the study objective. The paper also proposes an innovative ontology, referred to as Student Performance and Course, to enhance resource management and evaluation mechanisms on course, students, and MOOC performance by the faculty.

Explore poverty with statistical modeling: The bivariate polynomial binary logit regression (BPBLR).

Logit regression (or logistic regression) is a statistical analysis of categorical data. The binary responses have two categories. We present the Bivariate Polynomial Binary Logit Regression (BPBLR), which extends logit regression by modeling two correlated binary response variables.

Optimizing Xenograft Models for Breast Cancer: A Comparative Analysis of Cell-Derived and Patient-Derived Implantation Techniques in Pre-Clinical Research.

Purpose: The high mortality rate of breast cancer motivates researchers to search for effective treatments. Due to their ability to simulate human conditions, xenograft models such as CDX (Cell line-Derived Xenografts) and PDX (Patient-Derived Xenografts) have gained popularity in pre-clinical research. The choice of xenograft technique is influenced by the type of tumor employed, particularly in more aggressive tumor models like TNBC with metastases.

Pre-hormonal therapy combined with buccal mucosal graft for glans reconstruction in complete penile amputation: A case report and review of literature.

Penile amputation following circumcision is a rare but serious complication. Reconstructing the glans poses a complex surgical challenge, and several techniques have been proposed to address this issue. We present the case of a 10-year-old boy who experienced complete glans amputation 14 hours after circumcision.