1,460 results match your criteria: "Indira Gandhi Medical College.[Affiliation]"

Background: Information about the experience of practicing psychiatrists with the use of the Mental Health Care Act (MHCA), 2017, India, after 5 years of its promulgation has not been available.

Aim: The present study was carried out to understand the experience of the practicing psychiatrists in using and complying with the MHCA 2017 and to bring out the problems and suggested reforms, if any, in various provisions of the MHCA 2017.

Methods: An online survey by practicing psychiatrists of Indian Psychiatric Society on the various sections and provisions of the MHCA 17 was carried out through structured and open-ended responses.

View Article and Find Full Text PDF

Incipient and subclinical tuberculosis: a narrative review.

Monaldi Arch Chest Dis

January 2025

Department of Pulmonary Medicine, Indira Gandhi Medical College, Shimla, Himachal Pradesh.

Mycobacterium tuberculosis has been known to infect humans for eons. It is an airborne infectious disease transmitted through droplet nuclei of 1 to 5 µm in diameter. Historically, tuberculosis (TB) was considered a distinct condition characterized by TB infection and active TB disease.

View Article and Find Full Text PDF

Severe mental illness (SMI) encompasses depression, bipolar disorder, and schizophrenia which affect the daily quality of life. While it has a significant impact on their social life, it is also supposedly linked with various comorbidities, of which, cardiovascular disease (CVD) is the most frequently reported. Various biological, behavioral, and genetic mechanisms are thought to play a role: hypothalamic-pituitary-adrenal axis, autonomic nervous system dysregulation, inflammation, and psychotropic medications.

View Article and Find Full Text PDF

Infective endocarditis (IE) is a life-threatening condition with increasing global incidence, primarily caused by , especially methicillin-resistant strains (MRSA). Biofilm formation by is a critical factor in pathogenesis, contributing to antimicrobial resistance and complicating the treatment of infections involving prosthetic valves and cardiovascular devices. Biofilms provide a protective matrix for MRSA, shielding it from antibiotics and host immune defenses, leading to persistent infections and increased complications, particularly in cases involving prosthetic materials.

View Article and Find Full Text PDF
Article Synopsis
  • The study investigates the cognitive function of anemic pregnant South Indian women by measuring reaction times (RT) in visual and auditory tasks during early and late pregnancy.
  • Results indicated that women with anemia exhibited significantly longer reaction times compared to non-anemic women, with notable statistical differences in both visual and auditory assessments.
  • The findings suggest a clear connection between anemia and impaired cognitive processing, highlighting the need for better management of anemia during pregnancy to support cognitive health.
View Article and Find Full Text PDF

Background & objectives Biobanks are crucial for biomedical research, enabling new treatments and medical advancements. The biobank at the Madras Diabetes Research Foundation (MDRF) aims to gather, process, store, and distribute biospecimens to assist scientific studies. Methods This article details the profile of two cohorts: the Indian Council of Medical Research-India Diabetes (ICMR-INDIAB) study and the Registry of people with diabetes in India with young age at onset (ICMR-YDR).

View Article and Find Full Text PDF

Background: The World Health Organization defined adolescent age group as a life span between 10 and 19 years. Adolescence is a phase of transition from childhood to adulthood, it is a unique stage for human development and a very sensitive period for laying the foundation of good health. Investment in this life-stage yields triple dividend.

View Article and Find Full Text PDF

Background: Prescription auditing is a crucial tool for evaluating a range of concerns, including injectable usage, polypharmacy, the use of generic names, and the quality of treatment given to patients in primary care facilities. The objective of the study was to assess, using WHO core drug use indicators, the drug use patterns of general outpatients (OPD) at a rural healthcare facility.

Materials And Methods: A cross-sectional study was conducted in a rural peripheral health centre in Puducherry for a period of one year from September 2019 to August 2020.

View Article and Find Full Text PDF

Purpose: Soft tissue sarcomas (STS) due to their aggressive nature, pose challenges in achieving optimal local control (LC) rates following surgery. Brachytherapy offers precise delivery of high radiation doses to target tissues, potentially enhancing LC rates. This feasibility study explored the efficacy of perioperative high-dose-rate brachytherapy (PHDRB) and external beam radiation therapy (EBRT) in improving LC rates for STS, with a particular focus on interstitial brachytherapy and dose escalation strategies for high-risk patient sub-groups.

View Article and Find Full Text PDF

Introduction: Acute and chronic pancreatitis (CP) are inflammatory conditions of the pancreas that cause local and systemic complications. The epidemiology of these conditions are not well-known in India.

Methods And Analysis: We describe the protocol and procedures of a multicentre study for delineating the epidemiology of pancreatitis in India.

View Article and Find Full Text PDF

We hereby present a case of a 34-year-old male patient diagnosed with Behcet's disease where computed tomography revealed the presence of thrombosis and occlusion of the infrarenal aorta and bilateral renal arteries. Such a pattern of vascular involvement is an unusual and uncommon manifestation of Behcet disease.

View Article and Find Full Text PDF

Vulval Aggressive Angiomyxoma: A Giant Tumour Arising from Hidradenitis Suppurativa Scars.

Indian J Dermatol

October 2024

From the Department of Dermatology, Venereology and Leprosy, Indira Gandhi Medical College Shimla, Himachal Pradesh, India.

Aggressive angiomyxoma (AA) is a very rare tumour arising from the vulvovaginal mesenchymal tissue. The literature has not reported its co-existence with hidradenitis suppurativa (HS). A 30-year-old female presented with a giant pedunculated mass arising from a scarred and disfigured perineum for 3 years.

View Article and Find Full Text PDF

The Association of Lipid Abnormalities with Complications in Severe Scrub Typhus.

J Assoc Physicians India

December 2024

Professor, Department of Medicine, Indira Gandhi Medical College, Shimla, Himachal Pradesh, India, Corresponding Author.

Aim: To study abnormalities of lipids in patients suffering from severe scrub typhus and their relationship with complications.

Methods: This cohort study was conducted in patients of severe scrub typhus [immunoglobulin (IgM) positive by enzyme-linked immunosorbent assay (ELISA)] admitted to our institute from 1 August 2020 through 31 July 2021. The lipid profile was estimated initially at the time of hospitalization.

View Article and Find Full Text PDF

Purpose: The objective of this study was to develop and validate a questionnaire for analyzing Knowledge, Attitude, and Practices (KAP) about risk factors in otitis media (OM) in children among their caretakers.

Methods: The questionnaire was developed following a standardized protocol that consisted of a literature search, peer review, item generation, and expert validation, for construct, content and face validity of items in the questionnaire followed by a cross-sectional survey on 100 caretakers, this was followed by the reliability test of the items in Questionnaire.

Results: A KAP questionnaire with 24 items categorized under three domains knowledge, attitude, and practices was developed.

View Article and Find Full Text PDF

Background: Androgenetic Alopecia (AGA) refers to the appearance of common non-scarring progressive loss of terminal hair. Trichoscopy shows a magnified view of the hair shafts and hair follicle openings and helps us to diagnose, prognosticate and determine the disease severity.

Aims: The aim of the study was to identify the trichoscopic findings in patients with androgenetic alopecia and associate these findings with disease severity.

View Article and Find Full Text PDF
Article Synopsis
  • The text discusses the importance of forecasting future health issues in the USA for effective planning and public awareness regarding disease and injury burdens.
  • It describes the methodology for predicting life expectancy, cause-specific mortality, and disability-adjusted life-years (DALYs) from 2022 to 2050 using the Global Burden of Diseases framework.
  • The forecasting includes various scenarios to assess the potential impacts of health risks and improvements across the country, focusing on demographic trends and health-related risk factors.
View Article and Find Full Text PDF

Indian Trial of Tranexamic acid in Spontaneous Intracerebral Hemorrhage study protocol.

Int J Stroke

January 2025

Indian Council of Medical Research, Non-Communicable Diseases Section, New Delhi, India.

Rationale: Early mortality in intracerebral hemorrhage (ICH) is due to hematoma volume (HV) expansion, and there are no effective treatments available other than reduction in blood pressure. Tranexamic acid (TXA) a hemostatic drug that is widely available and safe can be a cost-effective treatment for ICH, if proven efficacious.

Hypothesis: Administration of TXA in ICH patients when given within 4.

View Article and Find Full Text PDF

Tuberculosis (TB) represents a significant communicable disease on a global scale. The clinical manifestations of abdominal TB frequently resemble those of various gastrointestinal disorders, potentially leading to delays in accurate diagnosis. From January 2012 to December 2019, consecutive patients aged 12 years and older, diagnosed with gastrointestinal TB at a tertiary care center in North India, were enrolled.

View Article and Find Full Text PDF

Atypical cutaneous leishmaniasis: a new challenge to VL elimination in South-East Asia.

Front Cell Infect Microbiol

November 2024

Department of Microbiology and Immunology, McGill University, Montreal, QC, Canada.

Visceral leishmaniasis (VL) caused by in South-East Asian endemic countries including India, Nepal and Bangladesh has been the primary focus of the ongoing VL elimination program. With a major reduction in VL cases resulting from the elimination program during the last two decades, the efforts are now focused on the challenges posed by potential reservoirs within the asymptomatic cases, HIV-co-infection VL cases and Post Kala-azar Dermal Leishmaniasis (PKDL) cases that continue to sustain the parasite transmission cycle in known and newer endemic zones. This article brings attention to a new potential parasite reservoir in the form of atypical cutaneous leishmaniasis (ACL) cases caused by novel genetic variants.

View Article and Find Full Text PDF

Objectives: Cervical cancer is the second most common malignancy among Indian women after breast cancer. This study was undertaken to determine the pattern of care, long-term survival outcomes, and prognostic factors for cervical cancer patients treated at a tertiary care cancer centre in North India.

Methods: Ten-year data was retrieved for 435 stage I-IVA carcinoma cervix patients treated between 2009 and 2019.

View Article and Find Full Text PDF
Article Synopsis
  • Soft tissue sarcomas (STSs) make up less than 1% of all malignant tumors in humans, and treatment for metastatic STSs focuses on palliative care due to poor prognosis.
  • A study evaluated the effectiveness of low-dose radiotherapy combined with metronomic therapy in 16 heavily treated patients with metastatic STSs, aiming to assess their response and quality of life.
  • Results showed that 43.75% of patients achieved a partial response, and all reported improved quality of life compared to their previous treatment, demonstrating potential benefits of this combined approach in managing STSs.
View Article and Find Full Text PDF

Purpose: To study the outcomes and complications of Nd: YAG laser capsulotomy in patients with uveitis.

Methods: This study retrospectively evaluated outcomes of Nd: YAG laser capsulotomy in 260 eyes of 260 patients with uveitis. The main indications for performing capsulotomy were a visually significant posterior capsule opacification (PCO) and inability to visualize the posterior segment.

View Article and Find Full Text PDF
Article Synopsis
  • - The resurgence of Nipah virus (NiV) in Kerala poses significant public health challenges, highlighting the need for proactive strategies to prevent future outbreaks due to its zoonotic nature and changing transmission patterns.
  • - Recent NiV outbreaks have presented atypical respiratory symptoms, complicating detection efforts, and emphasize the importance of regional surveillance and understanding the virus's new genotype.
  • - A comprehensive approach involving early detection, public awareness, and strong collaboration between government and health organizations is necessary to manage the impact of NiV and ensure public safety through ongoing research.
View Article and Find Full Text PDF