Utilization of Portable Brain Magnetic Resonance Imaging in an Acute Care Setting.

Background Magnetic resonance imaging (MRI) is an important noninvasive diagnostic tool used in multiple facets of medicine, especially in the assessment of the neurological system with increasing usage over the past decades. Advancement in technology has led to the creation of portable MRI (pMRI) that was cleared for use recently. Methodology A prospectively collected retrospective study was conducted at a single institution to include patients aged >18 years, admitted to the hospital, and requiring MRI for any brain pathology.

Intraventricular Anaplastic Pleomorphic Xanthoastrocytoma: Very Rare Localization and Early Recurrence of a Rare Tumor.

We report a rare case of an adult, with no previous history of seizures, found to have a large intraventricular Anaplastic Pleomorphic Xanthoastrocytoma (APXA). To the best of our knowledge, this is only the second documented report of an APXA located within the ventricular system in an adult. The tumor was characterized by anaplastic features and necrosis without an elevated mitotic index, and it recurred shortly after a gross total surgical resection.

C4 Nephritic Factors in C3 Glomerulopathy: A Case Series.

Background: C3 glomerulopathy (C3G) defines a group of rare complement-mediated kidney diseases with a shared underlying pathophysiology: dysregulation of complement in the fluid phase and glomerular microenvironment. Dysregulation can be driven by autoantibodies to C3 and C5 convertases.

Study Design: Case series.

Urothelial Carcinoma With Squamous Differentiation Is Associated With High Tumor Stage and Pelvic Lymph-Node Metastasis.

Background: Squamous differentiation occurs in up to 20% of urothelial carcinoma cases and is thought to be an unfavorable prognostic factor.

Methods: Data from urothelial carcinoma in patients treated with cystectomy from 2002 to 2014 at Roswell Park Cancer Institute were retrospectively reviewed. A 2-tier system was adopted for stage analysis.

The Use of a "Double-Triple Barrel" Technique during Minimally Invasive Multilevel Tubular Laminectomy. A Technical Note.

This report presents a modified use of multiple tubular retractors (that limits issues related to the sequential redocking of tubular systems) that may prove helpful in cases where a minimally invasive approach is utilized for the treatment of multilevel lumbar stenosis.

Sufentanil Sublingual Tablet System for the Management of Postoperative Pain after Knee or Hip Arthroplasty: A Randomized, Placebo-controlled Study.

Background: Complications with IV patient-controlled analgesia include programming errors, invasive access, and impairment of mobility. This study evaluated an investigational sufentanil sublingual tablet system (SSTS) for the management of pain after knee or hip arthroplasty.

Methods: This prospective, randomized, parallel-arm, double-blind study randomized postoperative patients at 34 U.

Clinical response to unintentionally rapid infusion of drotrecogin alfa (activated).

Purpose: The case of a patient with severe sepsis who received a bolus dose of 184 microg/kg of drotrecogin alfa (activated) over one hour is reported.

Summary: An 84-year-old woman who had undergone right total knee replacement was admitted to the hospital from a rehabilitation facility with an initial diagnosis of mental status changes and a suspected urinary tract infection. Examination of the patient's incision from her recent knee surgery revealed a discharge, and a culture was obtained.

Seven-year follow-up on lopinavir/ ritonavir monotherapy.

Previous studies of lopinavir/ritonavir (LPV/r) monotherapy have shown that over 70% of patients achieved HIV RNA levels <500 copies/mL over a follow-up period of 48 to 96 weeks, but the long-term durability is undetermined. Herein, the authors report 2 patients that started LPV/r monotherapy after virologic failure on an NNRTIbased regimen and have been successfully treated for greater than 7 years. Both patients demonstrated long-term control of viral replication over the course of treatment, although the first patient had 3 viral load blips and the second had 1 blip under 400 copies/mL.