1 results match your criteria: "Indian Ocean Dental School and Hospital[Affiliation]"
Salivary Her2/neu Levels in Differentiation of Oral Premalignant Disorders and Oral Squamous Cell Carcinomas.
Asian Pac J Cancer Prev
June 2016
Oral and Maxillofacial Pathology, Indian Ocean Dental School and Hospital, Arsenal, Republic of Mauritius E-mail : drprajashree@ gmail.com.
Article Synopsis
- - Oral squamous cell carcinoma (OSCC) develops from precancerous lesions, influenced by oncogene activation and tumor suppressor gene loss, with Her2/neu being a significant growth factor receptor related to these changes.
- - A study compared serum and salivary Her2/neu levels among healthy controls, patients with premalignant disorders, and those with OSCC, finding no significant differences in serum but higher salivary levels in OSCC patients.
- - The findings suggest that salivary Her2/neu could serve as a reliable marker for distinguishing between premalignant and malignant oral conditions, unlike serum levels, highlighting its potential role in early detection.