Regioisomers containing triarylboron-based motifs as multi-functional photoluminescent materials: from dual-mode delayed emission to pH-switchable room-temperature phosphorescence.

Triarylboron compounds have been established as promising candidates in optoelectronic applications. However, realizing multi-functional properties in triaryl boron-based materials remains challenging. Herein, we present two regioisomers, 1 and 2, designed judiciously by connecting a dimethylamino donor and a dimesitylboryl acceptor at 1,4 and 2,6-positions of the naphthalene spacer, respectively.

Lewis acid-catalyzed (3 + 2) annulation of bicyclobutanes with ynamides: access to 2-amino-bicyclo[2.1.1]hexenes.

Strain-release driven annulations with bicyclo[1.1.0]butanes (BCBs) have become an attractive area of research for the synthesis of bioisosteric bicyclohexane derivatives, which play a vital role in drug discovery.

Enhanced circularly polarized luminescence attained self-assembly of heterochiral as opposed to homochiral dipeptides in water.

Circularly polarized luminescence (CPL) is gaining interest across various disciplines, including materials science, pharmaceuticals, and sensing technologies. Organic molecules, due to their ease of synthesis and reduced toxicity, are a focus for achieving high dissymmetry values ( ) in CPL. Here, we present a low molecular weight molecule (1), a dipeptide (Ala-Phe) covalently linked with tetraphenyl-ethylene (TPE), an Aggregation-Induced Emission luminophore (AIE-gen).

Lewis acid-catalyzed diastereoselective formal ene reaction of thioindolinones/thiolactams with bicyclobutanes.

Bicyclo[1.1.0]butanes (BCBs), featuring two fused cyclopropane rings, have found widespread application in organic synthesis.

Rapid, microwave-assisted deposition of anisotropic silver nanostructures on various substrates.

A facile, rapid, and scalable microwave-assisted solvothermal technique (MAST) has been developed to deposit anisotropic silver nanoparticles (AgNP) on various substrates in a solution medium. SEM-EDS and XRD were used to characterize the morphology and structure of the deposits. Deposition on non-patterned aluminium led to near-spherical AgNP agglomerates all across the surface.

A water-soluble, cell-permeable Mn(ii) sensor enables visualization of manganese dynamics in live mammalian cells.

Central roles of Mn ions in immunity, brain function, and photosynthesis necessitate probes for tracking this essential metal ion in living systems. However, developing a cell-permeable, fluorescent sensor for selective imaging of Mn ions in the aqueous cellular milieu has remained a challenge. This is because Mn is a weak binder to ligand-scaffolds and Mn ions quench fluorescent dyes leading to turn-off sensors that are not applicable for imaging.

Synthesis, characterization, crystal structure, and fabrication of photosensitive Schottky device of a binuclear Cu(ii)-Salen complex: a DFT investigations.

This work explores one centrosymmetric binuclear Cu(ii)-Salen complex synthesis, characterization, photosensitive Schottky barrier diode (PSBD) function, and DFT spectrum. The crystal growth involves HL and Cu(NO)·3HO in CHOH + ACN (acetonitrile) solvent medium. Herein, structural characterization employs elemental, IR/Raman, NMR, UV-VIS, DRS, SEM-EDX, PXRD, SCXRD, and XPS analyses.

A water-soluble Pd molecular tweezer for selective encapsulation of isomeric quinones and their recyclable extraction.

Quinones (QN) are one of the main components of diesel exhaust particulates that have significant detrimental effects on human health. Their extraction and purification have been challenging tasks because these atmospheric particulates exist as complex matrices consisting of inorganic and organic compounds. In this report, we introduce a new water soluble PdL molecular architecture (MT) with an unusual tweezer-shaped structure obtained by self-assembly of a newly designed phenothiazine-based tetra-imidazole donor (L) with the acceptor -[(tmeda)Pd(NO)] (M) [ tmeda = ,,','-tetramethylethane-1,2-diamine].

A highly diastereoselective strain-release Doyle-Kirmse reaction: access to functionalized difluoro(methylene)cyclopropanes.

Difluoro(methylene)cyclopropanes (F2MCPs) show better anti-cancer properties and chemical reactivities compared to their nonfluorinated analogues. However, catalytic stereoselective methods to access these privileged motifs still remain a challenging goal. The Doyle-Kirmse reaction is a powerful strategy for the concomitant formation of carbon-carbon and carbon-sulfur bonds.

Correction: laser irradiation: the kinetics of the changes in the nonlinear/linear optical parameters of AsSeSb thin films for photonic applications.

[This corrects the article DOI: 10.1039/D1RA02368C.].

Role of mutations in a chemoenzymatic enantiodivergent C(sp)-H insertion: exploring the mechanism and origin of stereoselectivity.

New-to-nature enzymes have emerged as powerful catalysts in recent years for streamlining various stereoselective organic transformations. While synthetic strategies employing engineered enzymes have witnessed proliferating success, there is limited clarity on the mechanistic front and more so when considering molecular-level insights into the role of selected mutations, dramatically escalating catalytic competency and selectivity. We have investigated the mechanism and correlation between mutations and exquisite stereoselectivity of a lactone carbene insertion into the C(sp)-H bond of substituted aniline, catalyzed by two mutants of a cytochrome P450 variant, "P411" (engineered through directed evolution) in which the axial cysteine has been mutated to serine, utilizing various computational tools.

Annealing-induced phase transformation in InSeTe thin films and its structural, optical and morphological changes for optoelectronic applications.

InSe and InTe have great importance in various device fabrications. The present report is based on the annealing-induced phase formation of both InSe and InTe from InSeTe thin films at different annealing temperatures as found from the XRD analysis and well supported by the Raman study. The average crystallite size increased with a decrease in the dislocation density.

Photocatalyzed Dowd-Beckwith radical-polar crossover reaction for the synthesis of medium-sized carbocyclic compounds.

The Dowd-Beckwith reaction, a ring-expansion of carbonyl compounds alkoxy radicals, is a powerful approach for synthesizing medium to large-sized carbocyclic scaffolds, which takes advantage of existing ring structures and avoids entropic and enthalpic factors that arise from the end-to-end cyclization strategies. However, the Dowd-Beckwith ring-expansion followed by H-atom abstraction is still the dominating pathway, which hampers its synthetic applications, and there currently exist no reports on the functionalization of ring-expanded radicals using non-carbon based nucleophilic reagents. Herein, we report a redox-neutral decarboxylative Dowd-Beckwith/radical-polar crossover (RPC) sequence that delivers functionalized medium-sized carbocyclic compounds with broad functional group tolerance.

Lewis acid-catalyzed diastereoselective carbofunctionalization of bicyclobutanes employing naphthols.

Traditional radical-mediated ring-opening of bicyclo[1.1.0]butanes (BCBs) for cyclobutane synthesis suffers from poor diastereoselectivity.

A cationic amphiphilic peptide chaperone rescues Aβ aggregation and cytotoxicity.

Directing Aβ to adopt a conformation that is free from aggregation and cell toxicity is an attractive and viable strategy to design therapeutics for Alzheimer's disease. Over the years, extensive efforts have been made to disrupt the aggregation of Aβ using various types of inhibitors but with limited success. Herein, we report the inhibition of aggregation of Aβ and disintegration of matured fibrils of Aβ into smaller assemblies by a 15-mer cationic amphiphilic peptide.

On the specific heat capacity of HITEC-salt nanocomposites for concentrated solar power applications.

High specific heat capacity or of molten salt is crucial for concentrated solar power plants as it will enhance the energy density of thermal energy storage. It can be achieved by doping nanoparticles into molten salts. However, reported results show inconsistency in enhancement (positive and negative).

A bis-NHC-CAAC dimer derived dicationic diradical.

The isolation of carbon-centered diradicals is always challenging due to synthetic difficulties and their limited stability. Herein we report the synthesis of a -1,4-cyclohexylene bridged bis-NHC-CAAC dimer derived thermally stable dicationic diradical. The diradical character of this compound was confirmed by EPR spectroscopy.

Copper(ii) curcumin complexes for endoplasmic reticulum targeted photocytotoxicity.

Three copper(ii) complexes [Cu(cur)(L)(ClO)] (1-3), where Hcur is curcumin and L is 1,10-phenanthroline (phen, 1), dipyrido[3,2-:2',3'-]quinoxaline (dpq, 2), or dipyrido[3,2-:2',3'-]phenazine (dppz, 3) were synthesized, fully characterized by various physicochemical methods and evaluated for their light-assisted chemotherapeutic potential. The complexes [Cu(acac)(L)(ClO)] (4-6), where Hacac is acetylacetone and L is phen (in 4), dpq (in 5) and dppz (in 6), were synthesized and used as controls. The solid state structures of complexes 4 and 5 were determined by single crystal X-ray diffraction.

Selective separation of planar and non-planar hydrocarbons using an aqueous Pd interlocked cage.

Polycyclic aromatic hydrocarbons (PAHs) find multiple applications ranging from fabric dyes to optoelectronic materials. Hydrogenation of PAHs is often employed for their purification or derivatization. However, separation of PAHs from their hydrogenated analogues is challenging because of their similar physical properties.

Dynamic kinetic resolution of γ,γ-disubstituted indole 2-carboxaldehydes NHC-Lewis acid cooperative catalysis for the synthesis of tetracyclic ε-lactones.

The ubiquity of ε-lactones in various biologically active compounds inspired the development of efficient and enantioselective routes to these target compounds. Described herein is the enantioselective synthesis of indole-fused ε-lactones by the N-heterocyclic carbene (NHC)-Lewis acid cooperative catalyzed dynamic kinetic resolution (DKR) of generated γ,γ-disubstituted indole 2-carboxaldehydes. The Bi(OTf)-catalyzed Friedel-Crafts reaction of indole-2-carboxaldehyde with 2-hydroxy phenyl -quinone methides generates γ,γ-disubstituted indole 2-carboxaldehydes, which in the presence of NHC and Bi(OTf) afforded the desired tetracyclic ε-lactones in up to 93% yield and >99 : 1 er.

Higher-order assembly of BSA gold nanoclusters using supramolecular host-guest chemistry: a 40% absolute fluorescence quantum yield.

Herein, we report for the first time a highly emissive higher-order assembled structure of BSA-Au NCs in the presence of cucurbit[7]uril, which enhances the absolute fluorescence quantum yield of BSA-Au NCs up to 40%. Cucurbit[7]uril neutralizes the surface charge of BSA-Au NCs, and hence aggregation happens. This aggregation shows reversible disaggregation in the presence of adamantylamine.

Tuneable chemistry at the interface and self-healing towards improving structural properties of carbon fiber laminates: a critical review.

Carbon fiber reinforced epoxy (CFRE) laminates have become a significant component in aircraft industries over the years due to their superior mechanical and highly tunable properties. However, the interfacial area between the fibers and the matrix continues to pose a significant challenge in debonding and delamination, leading to significant failures in such components. Therefore, since the advent of such laminated structures, researchers have worked on several interfacial modifications to better the mechanical properties and enhance such laminated systems' service life.

From a Möbius-aromatic interlocked MnBH wheel to the metal-doped boranaphthalenes M@BH and MB 2D-sheets (M = Mn and Fe): a molecules to materials continuum using DFT studies.

The inherent tendency of BR fragments to undergo coupling is utilized to predict MBH and M@BH complexes (where M = Mn and Fe). Electronic structure analysis of MnBH (7) shows that the metal d-orbitals stabilize the interlocked boron wheel structure, forming an unprecedented geometrical pattern with Möbius aromaticity. The two additional electrons in Fe@BH (8) stabilize a twisted [10]boraannulene structure.