12 results match your criteria: "Indian Council of Medical Research -Regional Medical Research Center[Affiliation]"

Background: Undernutrition is a major public health challenge among Indian adolescents in India where 253 million of them are in the age group of 10-19 years. In spite of several intensive efforts through various program interventions and care, research studies find a less encouraging improvement in nutritional scenarios. The present systematic review aimed to determine the pooled prevalence and associated factors of undernutrition (stunting and underweight) among Indian adolescents.

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Article Synopsis
  • Tuberculosis (TB) remains a leading cause of death globally, highlighting the need for new preventive strategies, including vaccines.
  • A clinical trial in India will evaluate the safety and efficacy of two TB vaccine candidates, VPM1002 and Immuvac, in 12,000 healthy individuals who live with patients diagnosed with active TB.
  • The study will measure several outcomes, including the prevention of confirmed TB cases, adverse events, vaccine effectiveness across various age groups, and immune responses post-vaccination, with approvals from relevant ethics committees in place.
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Additive Manufacturing of Wet-Spun Polysulfone Medical Implants.

ACS Biomater Sci Eng

September 2023

Laboratory of Biomaterials and Regenerative Medicine for Advanced Therapies, Indian Council of Medical Research-Regional Medical Research Center, Bhubaneswar 751013, Odisha, India.

Research on additive manufacturing (AM) of high-performance polymers provides novel materials and technologies for advanced applications in different sectors, such as aerospace and biomedical engineering. The present article is contextualized in this research trend by describing a novel AM protocol for processing a polysulfone (PSU)/-methyl-2-pyrrolidone (NMP) solution into medical implant prototypes. In particular, an AM technique involving the patterned deposition of the PSU/NMP mixture in a coagulation bath was employed to fabricate PSU implants with different predefined shape, fiber diameter, and macropore size.

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Background: Inequalities in access to and utilization of maternal and child health (MCH) care are hampering progress on the path to achieving the Sustainable Development Goals. In a number of Low- and Middle-Income Countries (LMICs) population subgroups at disproportionate risk of being left behind are the urban poor. Within this neglected group is the further neglected group of the homeless.

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Bio-Nanohybrid Gelatin/Quantum Dots for Cellular Imaging and Biosensing Applications.

Int J Mol Sci

October 2022

Polymer Chemistry & Biomaterials Research Group, Ghent University, Krijgslaan 281-S4, 9000 Gent, Belgium.

The bio-nanohybrid gelatin protein/cadmium sulfide (Gel/CdS) quantum dots (QDs) have been designed via a facile one-pot strategy. The amino acids group of gelatin chelate Cd and grow CdS QDs without any agglomeration. The H NMR spectra indicate that during the above process there are no alterations of the gelatin protein structure conformation and chemical functionalities.

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Background: Since the novel SARS-CoV-2 has been detected and the ensuing pandemic, the search for a cure or prevention has been the only target of the medical fraternity. As the second wave racked havoc, vaccines seemed to be the only viable option to stop this global surge. World Health Organization (WHO) and subsequently the Government of India have issued emergency use authorization to two vaccines.

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Clinical progress of therapeutics and vaccines: Rising hope against COVID-19 treatment.

Process Biochem

July 2022

Department of Industrial and Engineering Chemistry, Institute of Chemical Technology, Indian oil Odisha Campus, Samantpuri, Bhubaneswar 751013, India.

Cases of deaths due to COVID-19 (COrona VIrus Disease-19) infection are increasing gradually worldwide. Immense research is ongoing to control this pandemic condition. Continual research outcomes are indicating that therapeutic and prophylactic agents are the possible hope to prevent the pandemic from spreading and to combat this increasing death count.

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Healable, Adhesive, and Conductive Nanocomposite Hydrogels with Ultrastretchability for Flexible Sensors.

ACS Appl Mater Interfaces

December 2021

Joint Laboratory of Advanced Biomedical Materials (NFU-UGent), Jiangsu Co-Innovation Center of Efficient Processing and Utilization of Forest Resources, Nanjing Forestry University, Nanjing 210037, P. R. China.

In recent years, conductive hydrogels have generated tremendous attention in biomedicals and bioelectronics fields due to their excellent physiochemical properties. In this study, a physically cross-linked conducting hydrogel has been designed in combination with cellulose nanocrystalline (CNC), polyacrylic acid (PAA) chains, laurel methacrylate, and sodium dodecyl sulfate. The obtained result shows that the hydrogel prepared is ultrastretchable, mechanically robust, transparent, biocompatible, conductive, and self-healing.

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Whey protein isolate (WPI) is a by-product from the production of cheese and Greek yoghurt comprising β-lactoglobulin (β-lg) (75%). Hydrogels can be produced from WPI solutions through heating; hydrogels can be sterilized by autoclaving. WPI hydrogels have shown cytocompatibility and ability to enhance proliferation and osteogenic differentiation of bone-forming cells.

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Angiogenesis is a physiological process involving the growth of new blood vessels, which provides oxygen and required nutrients for the development of various pathological conditions. In a tumor microenvironment, this process upregulates the growth and proliferation of tumor cells, thus any stage of angiogenesis can be a potential target for cancer therapies. In the present study, chitosan and his derivatives have been used to design novel polymer-based nanoparticles.

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Materials and Technologies to Combat Counterfeiting of Pharmaceuticals: Current and Future Problem Tackling.

Adv Mater

March 2020

Joint Laboratory of Advanced Biomedical Technology (NFU-UGent), College of Chemical Engineering, Nanjing Forestry University, 210037, Nanjing, P. R. China.

The globalization of drug trade leads to the expansion of pharmaceutical counterfeiting. The immense threat of low quality drugs to millions of patients is considered to be an under-addressed global health challenge. Analytical authentication technologies are the most effective methods to identify active pharmaceutical ingredients and impurities.

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