1 results match your criteria: "India. Electronic address: rahamanh@manipuruniv.ac.in.[Affiliation]"
The anti-oxidant enzyme, Prdx6 might have cis-acting regulatory sequence(s).
Int J Biol Macromol
April 2020
Department of Biotechnology, Manipur University, Imphal, Manipur 795003, India. Electronic address:
Article Synopsis
- Peroxiredoxin 6 (Prdx6) is a widely expressed enzyme essential for various biological functions and shows differences in peroxidase activity between humans and rats despite a minor variation in their amino acid sequences.
- The study found that this activity difference may be due to structural changes in the human variant, which enhances its flexibility and dynamics, particularly in its active site.
- These findings suggest that specific alterations in Prdx6 could influence its regulatory mechanisms and efficiency related to the thioredoxin fold, indicating the potential for cis-acting regulatory sequences.