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Efficacy of different doses of daily prophylactic iron supplementation in pregnant women: A systematic review and meta-analysis.

Clin Nutr ESPEN

December 2024

Department of Telemedicine and Regional Resource Centre, All India Institute of Medical Sciences, Rishikesh, Uttarakhand 249203, India. Electronic address:

Article Synopsis
  • Multiple studies have been conducted to find the best iron dosage for pregnant women, but there's no agreement on the appropriate amount to take for prevention of anemia.
  • A meta-analysis of 15 randomized controlled trials involving 2,726 participants showed that while blood hemoglobin levels didn't significantly differ between groups taking 60 mg or less and more than 60 mg of elemental iron, higher doses were associated with better changes in serum ferritin and iron levels.
  • The findings suggest that taking 60 mg of iron daily is more effective than taking only 30 mg to prevent anemia during pregnancy.
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