Analysis of Seroreactivity and Seropositivity in Balb/c Mice Experimentally Infected with Toxocara canis Using Two Recombinant (rTc-CTL-1 and rTES-120) Antigens.

Introduction: Toxocarosis in human beings is currently diagnosed by serological assay based on the detection of antibodies against Toxocara antigens. Toxocara canis larvae do not reach the adult stage in paratenic hosts like humans and mice. Therefore experimental infection in mice, which mimics the biology of human infection, might be relevant to get a better understanding of human toxocarosis.

Establishing an objective quantitative method for assessing the severity of plus disease in retinopathy of prematurity.

Background: To establish an objective method for assessing plus disease severity in retinopathy of prematurity.

Methods: Six images of plus diseases that were color-coded according to severity and published in the International Classification of Retinopathy of Prematurity, Third Edition (ICROP3) were analyzed. These images were individually processed, and the best-fit curve and vessel course in zone I were obtained using ImageJ software.

Perspectives of healthcare workers on drone-enabled healthcare delivery in challenging terrains of Manipur and Nagaland, India: a qualitative research.

Collaborative initiatives of the drone industry and healthcare sector are becoming a pivotal step in restructuring healthcare service delivery in India. This paper documents knowledge and perceptions of healthcare workers from various districts of Manipur and Nagaland towards the use of drones for medical supply in the region. The study utilized 27 in-depth interviews with healthcare workers to collect qualitative data, which was then analyzed using NVivo 14 for thematic and content analysis.

Biosimilars: A Critical Review of Development, Regulatory Landscape, and Clinical Implications.

The biopharmaceutical industry has witnessed significant growth in the development and approval of biosimilars. These biosimilars aim to provide cost-effective alternatives to expensive originator biosimilars, alleviating financial pressures within healthcare. The manufacturing of biosimilars is a highly complex process that involves several stages, each of which must meet strict regulatory standards to ensure that the final product is highly similar to the reference biologic.

Early childhood growth and nutritional status in India: trends in five National Family Health Surveys spanning 1992 and 2021.

Background/objective: To evaluate the weight and height status of under-five children between 1992 and 2021 in relation to nutritional context.

Subjects/methods: The study is based on the lengths/heights and weights of children <5 years in five national surveys (n = 505,026). After evaluating normality of the distributions, heights, and weights were expressed as z-scores relative to the WHO reference.

Investigation of corrosion and water absorption of biomass natural coir fiber/hBN reinforced epoxy hybrid composites using different optimisation approaches.

Agricultural waste or agro-waste, including natural fibers and particles from various crop parts, is increasingly recognized as a significant contributor to environmental issues. However, from a circular economy perspective, these materials present an opportunity to be repurposed into new, eco-friendly products. The present study, specifically focuses on understanding the effect of different factors, such as the particulate loading and the size (coir and hBN - 1 to 5 wt%; Coir Powder size (100-200 μm) of the particles on composite's corrosion rates and water absorption properties.

Does a gentamicin-coated intramedullary nail prevent postoperative infection in Gustilo type I and II tibial open fractures? A comparative study and retrospective analysis.

Purpose: Tibial open shaft fractures are very common and susceptible to infection, which can lead to significant morbidity especially infection and non-union. Antibiotic coated nail is one option for fixing open shaft tibial fractures to minimise infection. This study aimed to compare the clinical outcome of Gentamicin-coated tibial nails versus regular unreamed interlocking tibial nails in the treatment of type I and II tibial open fractures.

Nano-biopesticide formulation comprising of silver nanoparticles anchored to Ocimum sanctum: a sustainable approach to pest control in jute farming.

The jute hairy caterpillar, Spilosoma obliqua (Lepidoptera: Erebidae) is considered as one of the major threats to jute cultivation. The best eco-friendly methods to combat these jute pests involve administration of nano-biopesticides, as a successful alternative to the toxic chemicals. In this study, a nano-biopesticide formulation containing green synthesized silver nanoparticles (Ag NPs) using Ocimum sanctum leaf extract has been proposed.

Unveiling the potential of Aspergillus terreus SJP02 for zinc remediation and its driving mechanism.

In present study, 15 morphologically different fungi isolated from rhizopheric soils of an industrial area were screened for their Zn removal efficiency from aqueous solution. Isolate depicting highest potential was molecularly identified as Aspergillus terreus SJP02. Effect of various process parameters viz.

A fractal-fractional order modeling approach to understanding stem cell-chemotherapy combinations for cancer.

The main objective of this work is to study the mathematical model that combines stem cell therapy and chemotherapy for cancer cells. We study the model using the fractal fractional derivative with the Mittag-Leffler kernel. In the analytical part, we study the existence of the solution and its uniqueness, which was studied based on the fixed point theory.

Unraveling the interactive effect of opaque2 and waxy1 genes on kernel nutritional qualities and physical properties in maize (Zea mays L.).

The mutant waxy allele (wx1) is responsible for increased amylopectin in maize starch, with a wide range of food and industrial applications. The amino acid profile of waxy maize resembles normal maize, making it particularly deficient in lysine and tryptophan. Therefore, the present study explored the combined effects of genes governing carbohydrate and protein composition on nutritional profile and kernel physical properties by crossing Quality Protein Maize (QPM) (o2o2/wx1wx1) and waxy (o2o2/wx1wx1) parents.

High-performance triboelectric nanogenerators based on Ag-doped ZnO loaded electrospun PVDF nanofiber mats for energy harvesting and healthcare monitoring.

This study investigates the potential of zinc oxide (ZnO) and Ag-doped zinc oxide (Ag-ZnO) nanoparticles (NPs) (1, 3 and 5 wt%) electrospun into poly(vinylidene fluoride) (PVDF) based triboelectric nanogenerators (TENGs) to harness electrical energy from ambient mechanical vibrations. ZnO and Ag-ZnO NPs were developed using a co-precipitation method. 3 wt% Ag-ZnO doping was optimized to exhibit a higher β-crystalline phase in PVDF (PAZ3).

Multi scale multi attention network for blood vessel segmentation in fundus images.

Precise segmentation of retinal vasculature is crucial for the early detection, diagnosis, and treatment of vision-threatening ailments. However, this task is challenging due to limited contextual information, variations in vessel thicknesses, the complexity of vessel structures, and the potential for confusion with lesions. In this paper, we introduce a novel approach, the MSMA Net model, which overcomes these challenges by replacing traditional convolution blocks and skip connections with an improved multi-scale squeeze and excitation block (MSSE Block) and Bottleneck residual paths (B-Res paths) with spatial attention blocks (SAB).

Waste marble sludge and calcined clay brick powders in conventional cement farina production for cleaner built environment.

In the manufacturing of some sectors, such as marble and brick, certain byproducts, such as sludge, powder, and pieces containing valuable chemical compounds, emerge. Some concrete plants utilize these byproducts as mineralogical additives in Turkey. The objective of the experimental study is to ascertain whether the incorporation of waste from the marble and brick industries, in powder form, into cement manufacturing as a mineralogical additive or substitute is a viable option.

Evidence-Based Surgical Guidelines for Treating Children With Rhabdomyosarcoma.

Background: Surgery remains the cornerstone of treatment for rhabdomyosarcoma (RMS) in children. However, there is considerable variation in surgical management practices worldwide, highlighting the need for standardized Clinical Practice Guidelines (CPG).

Methods: The CPG development involved assembling a multidisciplinary group, prioritizing 10 key topic areas, conducting evidence searches, and synthesizing findings.

Essential oil composition, antidiabetic, cytotoxicity, antimicrobial, antioxidant activity, and molecular modeling analysis of secondary metabolites from .

, known as "Dhumuugaa" in Afan Oromo and "Sensel" or "Smiza" in Amharic, is traditionally used to treat ailments such as scabies, fever, asthma, diarrhea, malaria, and more. This study explored the chemical composition and biological activity of its extracts and isolated compounds. The essential oils were extracted using the hydrodistillation method, and their chemical composition was evaluated using GC-MS.

Dissipative constraint-based multi-area power system with time-varying delays and cyber-attacks.

This work describes the dissipative constraint-based load frequency control problem for multi-area power system under load disturbances. Particularly, a new model incorporating time-varying delays and cyber-attacks are widespread in communication networks, significantly impacting control and stability. Consequently, the state-space equations of the addressed model are formulated and analyzed under the impact of false data injection attacks, and time-varying delays.

Causes and determinants of infant mortality using verbal autopsy and social autopsy methods in a rural population of Odisha: a community-based matched case-control study.

Background: The avoidable causes of infant mortality should be identified, and interventions should be made to improve the infant mortality rate. The cause of infant deaths should be assessed in both medical and social contexts.

Objectives: We aimed to determine the medical causes of infant mortality by verbal autopsy and its determinants in two rural blocks of the Khordha district of Odisha and assess the pathway of care and delay in seeking care for the illness preceding infant death using the three-delay model.

Retinal graft dislocation managed by repeat autologous retinal transplant for refractory macular hole.

A septuagenarian man presented with a visual acuity of hand motions and a large refractory macular hole (MH). We performed an autologous retinal transplant (ART) and covered the graft with fibrin glue without any endotamponade. The autograft was found to have dislocated from the MH when the patient was reviewed 1 week later.

Clear cell variant of calcifying epithelial odontogenic tumour (Pindborg tumour) of the mandible.

A calcifying epithelial odontogenic tumour (CEOT) is a rare benign odontogenic tumour of epithelial origin accounting for approximately 1% of all odontogenic tumours. The intraosseous form occurs more commonly in the posterior mandible whereas the extraosseous form is common in the anterior maxilla. CEOT is often asymptomatic and presents with a painless swelling of the mandible.

Conduction system metastasis in a patient with carcinoma oesophagus.

A young man in his 30s presented to us with multiple episodes of syncope and exertional dyspnoea for the last 2 weeks. He was diagnosed with squamous cell carcinoma of the lower one-third of the oesophagus in 2021 for which he was treated with neoadjuvant chemoradiotherapy, followed by McKeown oesophagectomy. At 2-year follow-up, he had developed a soft tissue swelling in the scalp, which was diagnosed as a tumour recurrence and radiotherapy was initiated.