Augmenting cybersecurity through attention based stacked autoencoder with optimization algorithm for detection and mitigation of attacks on IoT assisted networks.

The Internet of Things (IoT) network is a fast-growing technology, which is efficiently used in various applications. In an IoT network, the massive amount of connecting nodes is the existence of day-to-day communication challenges. The platform of IoT uses a cloud service as a backend for processing information and maintaining remote control.

Fused deposition modeling process parameter optimization on the development of graphene enhanced polyethylene terephthalate glycol.

This study investigates the production of graphene-enhanced polyethylene terephthalate glycol (G-PETG) components using fused deposition modeling (FDM) and evaluates their mechanical properties, contributing to the advancement of additive manufacturing. Trials demonstrated notable improvements in mechanical performance, with optimal printing parameters identified using the Spice Logic Analytical Hierarchy Process (AHP). The effectiveness of this methodology is further compared with the Fuzzy Analytic Hierarchy Process (FAHP) combined with the Technique for Order of Preference by Similarity to Ideal Solution (TOPSIS).

A multiparametric screen uncovers FDA-approved small molecules that potentiate the nuclear mechano-dysfunctions in ATR-defective cells.

Targeting nuclear mechanics is emerging as a promising therapeutic strategy for sensitizing cancer cells to immunotherapy. Inhibition of the mechano-sensory kinase ATR leads to mechanical vulnerability of cancer cells, causing nuclear envelope softness and collapse and activation of the cGAS-STING-mediated innate immune response. Finding novel compounds that interfere with the non-canonical role of ATR in controlling nuclear mechanics presents an intriguing therapeutic opportunity.

Biodegradation of plasticizers by novel strains of bacteria isolated from plastic waste near Juhu Beach, Mumbai, India.

Phthalic acid esters are pivotal plasticizers in various applications, including cosmetics, packaging materials, and medical devices. They have garnered significant attention from the scientific community due to their persistence in ecosystems. The multifaceted aspects of PAEs, encompassing leaching, transformation, and toxicity, underscore their prominence as primary components of anthropogenic waste.

Isolation and characterization of Saprolegnia parasitica from cage-reared Pangasianodon hypophthalmus and its sensitivity to different antifungal compounds.

Saprolegniasis is one of the most dangerous fungal diseases of fish, causing significant mortality in fish hatcheries and young ones. The present study aimed to isolate and characterize the causative fungus from fingerlings of Pangasianodon hypophthalmus cultured intensively in freshwater cages in Indian reservoirs and to determine minimum inhibitory concentrations of different antifungal compounds against the fungal hyphae and zoospores. The fungal isolates grown on potato dextrose agar showed an abundance of gemmae, elongated mycelia, non-septate hyphae, primary zoospores, mature zoosporangia with numerous zoospores, cysts with bundles of long hairs and were further identified as Saprolegnia parasitica following PCR amplification and sequencing of internal transcribed spacer region.

Combination of paclitaxel with rosiglitazone induces synergistic cytotoxic effects in ovarian cancer cells.

Ovarian cancer is known to be a challenging disease to detect at an early stage and is a major cause of death among women. The current treatment for ovarian cancer typically involves a combination of surgery and the use of drugs such as platinum-based cytotoxic agents, anti-angiogenic drugs, etc. However, current treatment methods are not always effective in preventing the recurrence of ovarian cancer.

Unravelling the photosynthetic dynamics and fluorescence parameters under ameliorative effects of 24-epibrassinolide in wheat (Triticum aestivum L.) grown under heat stress regime.

An experiment was performed at the Banaras Hindu University, India to study the effect of terminal heat stress on photosynthetic dynamics and fluorescence parameters of wheat genotypes and ameliorative effects of epibrassinolide by taking two genotypes with four concentrations as foliar spray at two growth stages of wheat. The highest values were observed in plots foliar sprayed with 1.0 µM 24-epibrassinolide (T1) under normal conditions (D1) where the genotype Sonalika (V1) performed significantly well w.

Improved aquila optimizer for swarm-based solutions to complex engineering problems.

The traditional optimization approaches suffer from certain problems like getting stuck in local optima, low speed, susceptibility to local optima, and searching unknown search spaces, thus requiring reliance on single-based solutions. Herein, an Improved Aquila Optimizer (IAO) is proposed, which is a unique meta-heuristic optimization method motivated by the hunting behavior of Aquila. An improved version of Aquila optimizer seeks to increase effectiveness and productivity.

Revealing exchange bias in spin compensated systems for spintronics applications.

Antiferromagnetic materials offer potential for spintronic applications due to their resilience to magnetic field perturbations and lack of stray fields. Achieving exchange bias in these materials is crucial for certain applications; however, discovering such materials remains challenging due to their compensated spin structure. The quest for antiferromagnetic materials with exchange bias became a reality through our experimental study and theoretical simulation on and .

Predicting age at first calving of dairy breed calves using whale optimization-based ensemble learning framework.

Dairy product requirement and the demand-supply gap of milk in Ethiopia have been increasing at an alarming rate due to various factors such as shortage of animal's feeds, feed staffs, feed costs, and poor genetic merits of the local breeds of the country. This problem can be lessened by selecting best breed and modern animal breeding facilities, which require technologies like big data analysis and machine learning. In this study, a prediction model that can predict age at first calving of weaned calves based on their pre-weaning and weaning parameters, including dam's parity number, season of calving, birth weight, pre-weaning health status, pre-weaning average daily weight gain (ADG), weaning age and weaning weight is developed.

Flux jumps, cluster distribution model and vortex phase diagram of oxygenated YBaCuAlO single crystals for H|| ab.

This work reports magnetic field direction dependent second magnetisation peak (SMP) anomaly in single crystals of oxygenated [Formula: see text] for [Formula: see text] ab. Detailed investigations on crystal A revealed the direction dependence of SMP anomaly at temperatures below 25 K, above which the direction dependence vanishes. The state of spatial order of the vortex lattice was found to be correlated to the vortex lattice symmetry that underwent a change at certain fields and was captured via single flux jumps observed in the third and fifth quadrant of magnetisation hysteresis loops.

Global proteomics reveals pathways of mesenchymal stem cells altered by Mycobacterium tuberculosis.

Mycobacterium tuberculosis (M. tb) has a remarkable ability to persist inside host cells. Several studies showed that M.

Computational and biochemical characterization of the immobilized esterase of Salinicoccus roseus for pesticide degradation.

The continuous exposure of chemical pesticides in agriculture, their contamination in soil and water pose serious threat to the environment. Current study used an approach to evaluate various pesticides like Hexaconazole, Mancozeb, Pretilachlor, Organophosphate and λ-cyhalothrin degradation capability of esterase. The enzyme was isolated from Salinicoccus roseus.

Enhanced degradation of Ciprofloxacin (CIP) antibiotic and methylene blue (MB) dye using ZnO/GO nanocomposites under solar irradiation.

Modifying ZnO nanorods with graphene oxide (GO) is crucial for enhancing photocatalytic degradation by boosting the concentration of reactive oxygen species (ROS) in the reaction medium. In this study, we present a straightforward chemical synthesis of ZnO nanorods embedded on GO, forming a novel nanocomposite, GOZ. This composite serves as an efficient photocatalyst for the sunlight-driven degradation of methylene blue (MB) and ciprofloxacin (CIP).

Immediate Implant Placement in a Hypothyroid Geriatric Patient: Aesthetic Excellence, Secondary Stability, and Successful Outcome-A Case Report.

Placing an implant immediately into extraction sockets provides a distinct advantage over delayed placement, eliminating the need for a 4 to 6 months waiting period for bone formation. However, when patients present with hypothyroidism, the feasibility of immediate placement of dental implants becomes uncertain. This case involved a hypothyroid woman in her late 60s with loose lower anterior teeth.

Mental health and sleep routines: Uttarkashi, India tunnel collapse workers' experience.

Among the mental health outcomes and disaster types (determined by damage to life, property, long-term consequences, displacement, and unpredictability), floods are associated with anxiety and sleep problems, mudslides with anxiety and mood disturbance, volcanic eruptions with acute stress reactions, and earthquakes with anxiety, depression, and physical complaints. Disasters such as tunnel collapse are unique as it involves the healthy, without loss of personal property or displacement; hence, they can have very different health-related outcomes. In this study, we explore mental health and sleep-related issues in workers rescued from an under-construction collapsed tunnel trapped for 17 days.

Fuzzy modelling and cost optimization of fault-tolerant system with service interruption.

Redundancy and maintainability-supported fault-tolerant machining systems are used in many industries to achieve pre-specified reliability and system capability. In this investigation, a non-Markov model for the machining system has been developed by involving the concepts of server vacation, server breakdown, and reboot process. The server may fail and undergo primary repair which may be unsuccessful in recovering the server.

Second trimester medical abortion in acute promyelocytic leukaemia.

Acute promyelocytic leukaemia (APL) is a highly lethal haematological malignancy. It is rare in pregnancy and may be fatal if not managed promptly and appropriately. A woman in her 20s presented with high-grade fever at 16 weeks of her third pregnancy.