Instabilities, thermal fluctuations, defects and dislocations in the crystal-R-R rotator phase transitions of -alkanes.

The theoretical study of instabilities, thermal fluctuations, and topological defects in the crystal-rotator-I-rotator-II (X-R-R) phase transitions of -alkanes has been conducted. First, we examine the nature of the R-R phase transition in nanoconfined alkanes. We propose that under confined conditions, the presence of quenched random orientational disorder makes the R phase unstable.

Children's palliative care perceptions and educational needs among healthcare professionals in humanitarian settings.

Objectives: Explore humanitarian healthcare professionals' (HCPs) perceptions about implementing children's palliative care and to identify their educational needs and challenges, including learning topics, training methods, and barriers to education.

Methods: Humanitarian HCPs were interviewed about perspectives on children's palliative care and preferences and needs for training. Interviews were transcribed, coded, and arranged into overarching themes.

Red-light mediated formylation of indoles using a helical carbenium ion as a photoredox catalyst.

Low-energy photoredox catalysis has gained significant attention in developing organic transformations due to its ability to achieve high penetration depth and minimum health risks. Herein, we disclose a red-light ( = 640 nm)-mediated C-3 formylation of indoles utilizing a helical carbenium ion as a photocatalyst and 2,2-dimethoxy-,-dimethylethanamine as a formylating source. These protocols exhibit a broad substrate scope under mild conditions with efficient scalability for the synthesis of C-3 formylated indoles.

-β, β-β' trifused porphyrins: synthesis, spectral, electrochemical and DFT studies and their femtosecond third-order nonlinear optical properties.

-β, β-β' trifused porphyrins incorporating two distinct active methylene groups (MN = malononitrile and IND = 1,3-indanedione) and their corresponding metal complexes with Cu(II) and Zn(II) have been synthesized with good to excellent yields and characterized by various spectroscopic techniques and spectrometric methods. Single crystal X-ray analysis of the Zn(II) complex ZnTFPMB(MN) (where TFP = trifused porphyrin and MB = mono benzo) revealed a nonplanar 'armchair' type conformation with a twist angle of 24.10°.

: Mitochondrial signatures based analysis of an emerging public health threat in India.

Background: is a zoonotic tapeworm, commonly known as Asian It is an emerging sister species of with pigs as intermediate hosts. The present study aimed at genetic characterization and population structure analysis of metacestodes in slaughtered pigs in Haryana, north India.

Methods: In total, the vital organs of 253 slaughtered pigs were screened for the presence of metacestodes.

Implantoplasty-Aided Prosthetic Rehabilitation for the Management of Peri-Implantitis in Maxilla Reconstructed With Free Fibula Flap: A Clinical Report.

For managing peri-implantitis, a variety of treatment modalities involving both surgical and nonsurgical methods including implantoplasty have been proposed. Implants that are placed in a free fibula flap are more prone to peri-implantitis due to the absence of firm, keratinized mucosa. Prosthetic design that offers adequate hygiene access should be designed whenever possible; otherwise, it may lead to the accumulation of plaque or biofilm that may lead to peri-implant diseases.

1990-2041 Global burden of Burkitt lymphoma with 20 years forecast: A systematic analysis using the global burden disease of study of 2021.

Background: To investigate the trends in Burkitt lymphoma incidence, mortality, and disability-adjusted life-years, considering sex and age, from 1990 to 2021, with a 20-year forecast.

Method: Data regarding Burkitt lymphoma were extracted from the Global Burden of Disease study for the year 2021.

Results: Globally, there were 19,072 incident cases of Burkitt lymphoma in 2021.

Efficacy of spray flushing in the reprocessing of flexible endoscopes.

This article comments on the article by Du , who conducted a randomized controlled trial aiming at evaluating the effectiveness of a novel spray flushing system in cleaning flexible endoscopes while minimizing damage to the working channels. We share our perspective on the importance of improving endoscope reprocessing methods. The findings highlight the spray flushing system's capacity to improve cleaning efficacy while minimizing damage, suggesting that it might be important in enhancing endoscope reprocessing procedures.

Revisiting malignant gastric outlet obstruction: Where do we stand?

The scope of management of malignant gastric outlet obstruction is ever-expanding. The therapeutic use of endoscopy is gaining popularity not just owing to its technical advancement and satisfactory patient outcomes. With technical success rates close to 96%, stent placement for palliating gastric obstruction has ensured a median survival of about 2 months post-deployment of gastro-duodenal stents.

Detecting anomalies in smart wearables for hypertension: a deep learning mechanism.

Introduction: The growing demand for real-time, affordable, and accessible healthcare has underscored the need for advanced technologies that can provide timely health monitoring. One such area is predicting arterial blood pressure (BP) using non-invasive methods, which is crucial for managing cardiovascular diseases. This research aims to address the limitations of current healthcare systems, particularly in remote areas, by leveraging deep learning techniques in Smart Health Monitoring (SHM).

Protecting digital assets using an ontology based cyber situational awareness system.

Introduction: Cyber situational awareness is critical for detecting and mitigating cybersecurity threats in real-time. This study introduces a comprehensive methodology that integrates the Isolation Forest and autoencoder algorithms, Structured Threat Information Expression (STIX) implementation, and ontology development to enhance cybersecurity threat detection and intelligence. The Isolation Forest algorithm excels in anomaly detection in high-dimensional datasets, while autoencoders provide nonlinear detection capabilities and adaptive feature learning.

The functional connotations of iron deficiency-effect on neutrophil oxidative burst activity in preschool children.

Unlabelled: Iron deficiency anaemia (IDA) makes an individual prone to bacterial infections. The antimicrobial defence mechanism of neutrophils is orchestrated by Nicotinamide Adenine Dinucleotide Phosphate Hydrogen (NADPH) oxidative burst which is iron-dependent. The few previous studies documenting a decrease in neutrophil oxidative burst in iron-deficient children have been based mainly on the Nitro blue tetrazolium test (NBT).

Chondromyxoid fibroma of distal phalanx of great toe: a rare case report with literature review.

Chondromyxoid fibroma (CMF) in the foot is a rare condition. We report a case of CMF in a 7-year-old girl, affecting the distal phalanx of the great toe. Radiographs revealed a lytic lesion involving the entire distal phalanx, with destruction of both the medial and lateral cortices, while the articular surfaces remained intact.

Antifungal Susceptibility of Dermatophyte Isolates from Patients with Chronic and Recurrent Dermatophytosis.

Background: The widespread occurrence of chronic and recurrent dermatophytosis has significantly affected the quality of life for patients in India and beyond. Identifying the causative dermatophytes and understanding their antifungal susceptibility can aid clinicians in tailoring effective antifungal therapies.

Materials And Methods: Patients with chronic and recurrent dermatophytosis were enrolled, and conventional fungal cultures were conducted on skin scrapings.

Unusual Manifestation of Vitamin K Deficiency, Nodular Purpura: A Case Series.

Vitamin K deficiency is a common entity in infancy characterized by bleeding from various sites, intracranial bleeding being the most commonly reported feature. Nodular purpura is an uncommon manifestation of vitamin K deficiency in infancy with a few reported cases in literature. We present four cases of infants presenting with nodular purpura as a manifestation of late-onset vitamin K deficiency bleeding (VKDB).

Clinical and Histopathological Characteristics of Acquired Inflammatory Blaschko-Linear Disorders.

Introduction: Acquired inflammatory Blaschko-linear dermatoses have not been studied extensively. Descriptive studies on segmental vitiligo have yielded insights helpful in counseling patients. Similar insights are expected from studies on other acquired inflammatory Blaschko-linear diseases.

Ionized Plasma Jet Therapy in Removal of Dermatosis Papulosa Nigra.

Background: Dermatosis papulosa nigra (DPN) presents as benign skin growths, predominantly affecting women and often commencing during adolescence. Treatment is sought due to its cosmetic impact, with available modalities often posing risks of scarring and pigmentary changes.

Materials & Methods: This study investigates the efficacy of ionized plasma jet therapy (IPJT) in ten DPN patients at a tertiary care hospital in central India.

A Survey on Quality of Services, Training, and Attitude of Dermatology Trainee Residents About Sexually Transmitted Infections in Teaching Hospitals Across India.

Introduction: The incidence of sexually transmitted infections (STIs) has increased disproportionately to STI services. It is uncertain how many residents trained in STI services continue them. This study assessed the self-rated quality of training and attitudes about STI services amongst residents of Indian teaching hospitals.

Clinical and Laboratory Parameters of Metabolic Syndrome in Chronic Spontaneous Urticaria: A Cross-Sectional Study.

Background: Chronic spontaneous urticaria (CSU) appears to share some pathomechanisms with metabolic syndrome (MS), such as proinflammatory state, increased oxidative stress, changes in adipokine profile, and coagulation system activation.

Aim And Objectives: To evaluate clinical and laboratory parameters of MS in CSU patients and to assess relationship of MS with duration and severity of CSU, Ig-E, thyroid-stimulating hormone (TSH), C-reactive protein (CRP), and autologous serum skin test (ASST).

Materials And Methods: A hospital-based cross-sectional study was conducted on 131 CSU cases and 131 controls who were age- and sex-matched.