879,641 results match your criteria: "India; Mazumdar Shaw Center for Translational Research[Affiliation]"

As the COVID-19 pandemic began in 2020, plastic usage spiked, and microplastic (MP) generation has increased dramatically. It is documented that MP can transfer from the source to the ocean environment where they accumulate as the destination. Therefore, it is essential to understand their transferring pathways and effective environmental factors to determine the distribution of MPs in the marine environment.

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Introduction And Importance: Adenosquamous carcinoma (ASC) of the colon is a rare malignancy, representing approximately 0.06 % of colorectal cancers (CRC). It is characterized by the coexistence of adenocarcinoma and squamous cell carcinoma components.

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Background: Falls are some of the most common childhood injuries. However, for vulnerable children in low- and middle-income countries (LMICs) such as India, mortality from a fall is nearly three times that of high-income countries. Despite fall being a leading cause of paediatric injury, detailed data from LMICs remain sparse.

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Bio-concentration of hazardous metals in migrant shorebirds in a key conservation reserve and adjoining areas on the west coast of India.

Ecotoxicol Environ Saf

January 2025

Department of Biology, United Arab Emirates University, Al Ain 15551, United Arab Emirates; Department of Science, The Natural History Museum, Cromwell Road, South Kensington, London SW7 5BD, UK. Electronic address:

Heavy metal pollution is a growing environmental concern as it causes the degradation of wetlands by affecting the organisms at different trophic levels. Shorebirds typically feed on benthic invertebrates including polychaete worms, crustaceans and molluscs. Thus, the assessment of bioconcentration of heavy metals in shorebirds provides an insight into the extent of bioaccumulation of these hazardous metals in the upper trophic levels.

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Preclinical pharmacokinetics, absolute bioavailability and dose proportionality evaluation of bioactive phytochemical Withanone in rats.

Bioorg Chem

January 2025

Pharmaceutics & Pharmacokinetics Division, CSIR-Central Drug Research Institute, Lucknow 226031, India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad 201002, India; Institute of Cancer Therapeutics, School of Pharmacy and Medical Sciences, Faculty of Life Sciences, University of Bradford, Bradford BD7 1DP, United Kingdom. Electronic address:

Withanone (WN), a bioactive phytochemical isolated from the medicinal herb Withania somnifera, has shown multiple pharmacological and therapeutic successes, including neuroprotective and anti-cancer activities. However, detailed pharmacokinetic (PK) properties of pure WN were not well defined. Pharmacokinetic (PK) characteristics, dose proportionality, and absolute bioavailability of pure WN were explored in rats using an efficient, reliable, and sensitive LC-MS/MS assay to address this gap.

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Radiological considerations in using uranium mine waste rock for road construction materials.

J Environ Radioact

January 2025

Health Physics Division, Bhabha Atomic Research Centre, Mumbai, 400085, India; Homi Bhabha National Institute, Anushakti Nagar, Mumbai, 400094, India.

India's road construction is vital for its infrastructure growth, requiring approximately 20,000 tons of high-quality aggregates per kilometer - materials that are increasingly scarce, leading to higher costs and delays. The industrial sector, a cornerstone of the Indian economy, also struggles with waste management. Earlier studies suggested that industrial waste can be used in road construction materials however, the radiological considerations were not focused.

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Primary intrarenal hemangioma - A series of 39 cases.

Ann Diagn Pathol

January 2025

Department of Pathology and Laboratory Medicine, Brigham and Women's Hospital, Boston, USA. Electronic address:

Intrarenal hemangiomas lack concise clinicopathologic information, due to the predominance of single case reports and inclusion of other vascular neoplasms and hemangiomas of perirenal, hilar, and renal vein origin. Herein, in this multi-institutional study we evaluate clinicopathologic features of 39 intrarenal hemangiomas. The median age was 62 years (range = 27-94 years; 2:1 male to female ratio), with left-sided predominance (left = 21, right = 13; one case was bilateral).

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There is resurgent interest in making agriculture more "nutrition sensitive" to address longstanding rural health disparities. Yet, the relations between agri-ecological systems and producer wellbeing and health are complex, and approaches to studying them are scattered across multiple disciplinary traditions. This paper forges a methodological framework to study how bodily and social wellbeing may be facilitated/hindered amongst individuals engaged in agriculture by centering the material body within agriculture-nutrition analyses.

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Background: PFAS contamination is a global issue, affecting various food sources, especially animal-based products like eggs and dairy.

Objective: Collect scientific evidence of the presence of PFAS in diverse food and edible resources along with the related risks to human health, pursuing the following objectives: determination of the level of terrestrial food chain contamination; determination of the related human health risk.

Data Source: Scopus, PubMed, and Web of Science databases.

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Background: Around five billion people globally lack access to safe, timely, and affordable surgical facilities and care in low-income and middle-income countries (LMICs). Global initiatives have been launched, including efforts led by organizations. Also, regional efforts have shed light on the unique challenges faced by different areas within LMICs.

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In the present study, we investigated the dinoflagellate assemblages in the upper water column (< 150-m depth), focusing on the suboxic waters of the eastern Arabian Sea (EAS) along 68°E from 8°N to 21°N during the southwest monsoon 2020 (SWM-2020). Dinoflagellate abundance was higher in the upper water column (0-80-m depth, mean ± SD = 411 ± 903 cells L) compared to deeper waters (80-150-m depth, mean ± SD = 128 ± 216 cells L). Among 11 identified taxonomic dinoflagellate orders, Peridinales were predominant in the upper waters column (71%, mean ± SD = 285 ± 858 cells L).

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The submarine groundwater discharge (SGD) into the sea is known to alter various biotic and abiotic properties of coastal waters. However, its influence on the lower trophic levels, namely, meiofauna, is poorly understood. This study highlights the impact of SGD on the density, distribution, and diversity of intertidal meiofaunal communities along the subterranean estuaries (STEs) of the southwest coast of India (Arabian Sea).

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Utilizing metal/nanoparticle (NP)- tolerant plant growth-promoting rhizobacteria (PGPR) is a sustainable and eco-friendly approach for remediation of NP-induced phytotoxicity. Here, Pisum sativum (L.) plants co-cultivated with different CuO-NP concentrations exhibited reduced growth, leaf pigments, yield attributes, and increased oxidative stress levels.

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XR.

Br Dent J

January 2025

Research & Evidence (RF&E), New Delhi, India.

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'Double cancer'.

Br Dent J

January 2025

Research & Evidence (RF&E), New Delhi, India.

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Catharanthus roseus leaves have been traditionally described to possess potent antidiabetic activity and some leaf-specific alkaloids, including vindoline, have been studied for their antidiabetic potential. The aim of the present study was to validate the antidiabetic property of the plant with special reference to vindoline. An Ayurveda-based method was used to prepare the Swaras [leaf juice extract (LJE)] of three familial C.

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Biological and environmental degradation of two-dimensional materials.

Nat Rev Chem

January 2025

CNRS, Immunology, Immunopathology and Therapeutic Chemistry, UPR 3572, University of Strasbourg, ISIS, Strasbourg, France.

As the use of two-dimensional materials continues to grow, so too does the need to understand the environmental and biological impact of such materials. Degradation is a critical step in the life cycle of any material, but the majority of such knowledge is obtained from test tube and in vitro studies. Therefore, there remains a gap in understanding the degradability of two-dimensional materials in complex systems (in vivo) and in different ambient environments.

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This manuscript proposes the Jellyfish Search Optimization (JSO) algorithm-based Fractional Order Proportional-Integral-Derivative (FOPID) controller tuning for a paper machine headbox. The novelty of this method lies in integrating the JSO technique for optimizing the parameters of the FOPID controller to monitor and control headbox pressure and stock level efficiently and effectively. The JSO algorithm ensures optimal tuning of controller parameters by minimizing error indices such as Integral of Squared Error (ISE), Integral of Time Absolute Error (ITAE), and Integral of Absolute Error (IAE).

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Higher-end science and technology facilitate the human community with a sophisticated life despite it curses by abundant pollution. The alarming demand for sustainability pressurizes the manufacturing sector to ensure sustainable manufacturing. Since Molybdenum di sulfide (MoS) and avocado oil are known solid and liquid lubricants respectively, hence, it is a worthwhile attempt to implement the bio-based degradable avocado oil enriched with nano Molybdenum di sulfide (nMoS) particles as a potential machining fluid for CNC-end milling.

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Soil reinforcement is one of the techniques used to enhance the engineer characteristics of the soil. Various techniques can be employed to stabilise problematic soils, such as soft clay. These include the utilisation of portland cement, lime, fly ash, ground freezing, jet grouting, prefabricated vertical drains, and thermal approaches.

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Coal is a critical energy resource for global industries, and its extraction from open-pit mines requires effective slope stability management to ensure safe and efficient operations. This study evaluates the slope stability of the Tolay open-pit coal mine in Ethiopia, located in the Jimma zone, where geological conditions, including basalt, mudstone, and weathered soil layers, influence slope behaviour. The primary objective was to assess slope stability and recommend optimization strategies for safer mining.

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In South Asia, declining water tables due to increased irrigation and labor shortages for manual weeding pose significant challenges for wheat production. Additionally, herbicide resistance, often resulting from poor management practices, further complicates weed problems. The objective of this study was to assess the impacts of traditional irrigation regimens (IRs) and herbicide application on wheat crops.

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