MAFLD: Exploring the Systemic Effects Beyond Liver.

Metabolic dysfunction-associated fatty liver disease (MAFLD) is a growing global health concern which is driven by the increasing prevalence of diabetes and obesity. MAFLD is characterized by excessive fat accumulation in the liver, which encompasses a range of conditions, from simple hepatic steatosis to more severe forms. This condition is associated with various complications, including chronic kidney disease (CKD), Cardiovascular Disease (CVD), liver cirrhosis, and even malignancy.

Lingual Arch-supported Open Coil Space Regainer.

Aim And Background: The lingual arch has been widely used as a space maintainer in the lower arch during the mixed dentition phase, and the open-coil space regainer (OCSR) has been used for localized space regaining. However, an appliance consisting of both has not been previously documented. This case report highlights the advantages of using a lingual-arch-supported OCSR for regaining lost space.

Perception of Pedodontists Regarding Dental Care in Children with Special Needs in India: A Cross-sectional Study.

Background: Pedodontists have a vital role in maintaining the overall health of children with special health care needs (CSHCN) by providing basic, preventive, comprehensive, and restorative dental care to such children. In doing so, Pedodontists face many challenges due to several environmental and nonenvironmental barriers.

Aim: The aim is to gain insight into the perceptions of Pedodontists in India on providing oral health care to CSHCN and the challenges they encounter in doing so.

A Comparative Evaluation of Three Different Modeling Videos on Dental Anxiety of 3-6-year-old Children Requiring Treatment under Local Anesthesia: A Parallel, Randomized Controlled Trial.

Introduction: Video modeling is one of the most recommended techniques for modifying children's behavior during dental procedures.

Aim: To comparatively evaluate the three different modeling videos on dental anxiety of 3-6-year-old children requiring treatment under local anesthesia (LA).

Settings And Design: A parallel, randomized controlled trial was conducted in the Department of Pediatric Dentistry after obtaining clearance from the ethical committee.

Preserving Integrity: Investigating the Influence of Disinfecting Agents on Polymethylmethacrylate Dental Prosthesis Surface Characteristics in Children.

Introduction: In children, polymethylmethacrylate (PMMA) is a commonly used material for fabrication of dental prostheses, such as obturators, removable space maintainers, habit-breaking appliances, removable orthodontic appliances, and removable partial and complete dentures. Regular cleaning of such prostheses is vital for maintaining the health of the oral tissues as well as the longevity of the prosthesis. The chemical method of disinfection, using different chemical cleansers, is commonly used for cleaning a dental prosthesis.

Comparative Evaluation of pH, Calcium Ion Release, and Setting Time of Premixed and Freshly Mixed Tricalcium Silicate-based Endodontic Materials: An Study.

Background And Objective: During the last 200 years, there have been many changes in the way of performing endodontic treatment. The increased demand from patients for saving their teeth has led to the development of various innovative equipment and advances in the field of material sciences. Thus, the standard protocol of endodontic treatment has undergone several modifications.

Clinical and Radiographic Evaluation between Conventional Mineral Trioxide Aggregate and Gel-based Mineral Trioxide Aggregate in Indirect Pulp Therapy: A Randomized Clinical Trial.

Background: Indirect pulp treatment (IPT) is often employed in dentistry as a valuable technique for preserving dental vitality. While mineral trioxide aggregate (MTA) remains a popular choice, the need for materials with shorter setting times, lower costs, and minimized discoloration concerns has led to the exploration of alternative options.

Aim: To evaluate and compare the radiographic and clinical outcomes of gel-based MTA Kids e-MTA (Kids-e-Dental, Mumbai, India) with MTA (ProRoot MTA, Dentsply Tulsa, Johnson City, TN, USA).

Comparison of Chairside Cooperative Ability with Social Quotient of Mentally Challenged Children.

Aims And Background: Fostering a positive dental attitude in children to enhance their oral health status and engaging them positively throughout their dental experience is the cornerstone of pediatric dentistry practices. The behavior of the child in a dental setting depends upon their emotional, psychological, and mental developmental state. Children with special health needs tend to have more anxiety than healthy children.

Effectiveness of an External Cooling and Vibrating Device vs Counterstimulation in Reducing Discomfort of Inferior Alveolar Nerve Block in Pediatric Dental Patients: A Single-blinded Randomized Controlled Trial.

Background: Pain management in pediatric patients during dental procedures is very important. Here, the traditional method of behavior management is compared with novel methods.

Aim: To compare and determine the effectiveness of an external cooling and vibrating device vs counterstimulation with the conventional technique in reducing the fear and discomfort of pediatric dental patients aged 5-7 years during inferior alveolar nerve block (IANB).

The Effectiveness of E-Learning Anticipatory Guidance on Early Childhood Caries among the Mothers of Children Aged 9-24 Months during the Pandemic: A Nonrandomized Controlled Trial.

Background: Early childhood caries (ECC) is a multifactorial disease with known etiologic factors and can be very devastating to the oral and general well-being of a child, including psychological impacts on a growing child. Young children constitute a vulnerable population because of their dependence and inability to communicate their needs. Oral health disparities continue to pose critical challenges, as ECC is the most common chronic disease of childhood.

Efficacy of SAVE: A Novel Maxillary Protraction Device-A Finite Element Analysis.

Introduction: This study describes a novel device known as "SAVE" to effectively protract the deficient maxilla in class III malocclusion by quantifying and evaluating the changes in the maxilla through a finite element analysis (FEA).

Materials And Methods: The patented novel SAVE device was three-dimensionally modeled using Autodesk Fusion 360. An existing computed tomography (CT) scan of a patient exhibiting class III malocclusion was used to generate a finite element (FE) model.

An Evaluation of Changes in Salivary pH in 3-9-year-old Children Using Chewing Gums (Xylitol) and Lollipops (Xylitol + Erythritol).

Objectives: To evaluate the change in salivary pH using xylitol- and erythritol-containing lollipops and chewing gums, and assess the correlation between sugar substitutes and change in pH levels of saliva.

Materials And Methods: The present crossover study was conducted in 60 children between 3 and 9 years of age from a private school who had not received any meal for 2 hours prior to examination. There were three groups in this study: group I, control group (rinsing with tap water); group II, experimental group (with sugar substitute lollipops); and group III, experimental group (with sugar substitute chewing gums).

Estimation and Correlation of Human Leukocyte Antigen-DR and Human Leukocyte Antigen-DQ in Children with and without Severe-early Childhood Caries: A Randomized Clinical Trial.

Background/aim: Early childhood caries (ECC) is a prevalent dental disease, influenced by genetic and environmental factors. Human leukocyte antigens (HLA) have been suggested as a predisposing factor. This study aims to estimate and correlate HLA-DR and HLA-DQ activity in the saliva of caries-active and caries-free children, potentially aiding disease diagnosis and prevention.

Comparative Evaluation of Plaque Removal Potential of Manual Electrical and Chewable Toothbrushes in Children: A Clinical Trial.

Aim And Background: To evaluate and compare the efficiency of a manual, electrical, and chewable toothbrush for plaque removal in children.

Materials And Methods: A total of 58 children aged 8-14 years who reported to the Department of Pedodontics. The children and guardians were familiarized with the disclosing agent, manual toothbrush, electrical toothbrush, and chewable toothbrush before the commencement of the study with the help of video and verbal demonstrations.

Incidence of Tooth-related Soft Tissue and Intraosseous Pathologies in Pediatric Population: A Retrospective Analysis of 3,398 Cases.

Aim: To assess the prevalence of tooth-related, soft tissue, and intraosseous pathologies in the pediatric population (0-17 years) in a South Indian dental teaching institution and to compare the results with previous literature.

Materials And Methods: Clinical data from the pedodontics department and histopathological records from the oral pathology department were analyzed from the year 2010 to 2022 and grouped into two major categories: group I, abnormalities of teeth, and group II, intraosseous and mucosal/soft tissue lesions. The data were entered into a Microsoft Excel spreadsheet, and descriptive analysis was conducted using Statistical Package for the Social Sciences (SPSS) software, version 26.

An Comparative Analysis of Pain Perception in Children Following Lidocaine Gel, Clove Oil, and Precooling for Intraoral Injections: A Pilot Study.

Background: Dental anxiety about injections are common challenge in pediatric dentistry, often leading to delayed dental treatment.

Aim: The aim of the study was to evaluate the anesthetic effectiveness of three different topical agents in pediatric dental procedures.

Settings And Design: The study was a cross-sectional study carried out in the department of pediatric and preventive dentistry.

Evaluation of the Quality of Educational Content of YouTube Videos on Silver Diamine Fluoride.

Aim: The aim of this research is to assess the accuracy and educational content concerning silver diamine fluoride (SDF) videos available on YouTube.

Materials And Methods: Videos were sought on YouTube using relevant keywords related to SDF in pediatric dentistry the Google Trends application. There were a total of 70 videos accessible.

Lesch-Nyhan Syndrome and Oral Self-injury: A Systematic Review of Case Reports.

Background: This systematic analysis of case reports aimed to compile available knowledge and identify trends in disorder onset, symptoms, treatment, and possible interventions across individual cases associated with Lesch-Nyhan syndrome (LNS) oral self-injury.

Materials And Methods: "Lesch-Nyhan syndrome" and "oral self-mutilation" were entered as keywords in four search engines. All cases reporting the patients' demographics and documented episodes of self-mutilation, with details on treatment and management, were included.

Prevalence and Correlation of Lip Shapes and Arch Forms in Primary Dentition of Children between 3-6 Years of Age: A Cross-sectional Study.

Aims And Background: The study of the morphology of soft tissues as well as hard tissues of the orofacial region holds prime importance. A very less information is known about the lips (soft tissues) and maxillo-mandibular arches (hard tissue structures) in primary dentition. Henceforth, there is a need to classify, find the prevalence and correlation of various lip shapes, and arch forms in primary dentition.

Evaluating the Incidence of Incidental Gallbladder Carcinoma in a Tertiary Care Centre: A Retrospective Analysis in North India.

Background Incidental gallbladder carcinoma (IGBC) remains a significant clinical challenge, with its diagnosis often delayed due to the asymptomatic nature of the disease and its incidental discovery post-cholecystectomy. This study's aim is to calculate incidence in a high-risk, region-specific (North Indian) population and also to provide novel insights into clinical presentation as well as macroscopic and histopathological features of IGBC. Material and methods This retrospective observational study spanned four years (August 2013 to July 2016) and included a total of 3096 cases.

Sociodemographic Factors and Awareness of Consanguineous Marriages in Rural Northern Karnataka: A Cross-Sectional Study.

Background Consanguineous marriages, defined as unions between closely related individuals, are influenced by a complex interplay of cultural, social, economic, religious, and demographic factors. These marriages are prevalent among communities such as Hindus, Muslims, Jews, Buddhists, Christians, and Parsis in Southern and Western Asia, with significant regional variations within India. There is a lack of appropriate decision-making among women in consanguineous unions, particularly those with a low level of educational attainment, which leads to an increase in the prevalence of consanguineous marriages.

The Outcomes of IgA Nephropathy With Nephrotic Syndrome: A Clinicopathological Study From Northern India.

Introduction Nephrotic syndrome, an unusual clinical presentation of IgA nephropathy (IgAN), occurs only in a few cases. The data regarding its clinical characteristics and treatment outcomes are lacking. Material and methods In this retrospective analysis, we reviewed kidney biopsies conducted between January 2007 and December 2018.

Integration of Three-Dimensional Scanning and Computer-Aided Design/Computer-Aided Manufacturing (CAD/CAM) Technology in Routine Prosthodontic Practice: A Cross-Sectional Study in Kerala.

Background: Digital dentistry has transformed all aspects of dentistry, especially prosthodontics, and is increasingly used for diagnosis, treatment planning, execution, student training, and research. This study aimed to assess the perception, attitude, and practice of digital technology in prosthodontics among dental professionals in Kerala, India.

Materials And Methods: A cross-sectional, questionnaire-based study was conducted among dental professionals in Kerala.

Clinical and Hematological Characteristics of Vitamin B12 Deficiency and Evaluation of the Therapeutic Response to Vitamin B12 Supplementation.

Background Vitamin B12 deficiency, or cobalamin deficiency, is common among populations with low consumption of animal-based products, mainly in India, due to religious and socioeconomic factors, which significantly increase the deficiency rate. The condition has been characterized by a wide range of clinical and hematological symptoms, mainly affecting the blood and nervous system. This study aims to assess the clinical and hematological characteristics of patients with vitamin B12 deficiency and assess the therapeutic response to supplementation with vitamin B12.

Optimizing Premenopausal Hormone Receptor-Positive Human Epidermal Growth Factor Receptor 2-Negative Early Breast Cancer Management in India: Insights From Expert Consensus.

This research aims to optimize adjuvant ovarian function suppression (OFS) for premenopausal Indian women with hormone receptor-positive (HR+) /human epidermal growth factor receptor 2-negative (HER2-) early breast cancer (eBC). To address specific challenges identified in clinical practice, a comprehensive questionnaire consisting of 21 statements was developed. These statements were reviewed and validated by a scientific committee, ensuring their accuracy and relevance to the study's objectives.