Antibacterial Activity of Silver-Modified CuO Nanoparticle-Coated Masks.

A green and cost-effective sonochemical synthetic method was followed for coating silver-modified copper oxide (Ag-CuO) nanoparticles (NPs) on disposable surgical mask. The NP-coated masks were systematically characterized using XRD and FT-IR for understanding the structural and surface functionalities. In addition, the field emission scanning electron microscopy (FE-SEM) analysis showed the homogeneous coating of Ag-CuO NPs over the mask fibers.

Multimodality Fusion Aspects of Medical Diagnosis: A Comprehensive Review.

Utilizing information from multiple sources is a preferred and more precise method for medical experts to confirm a diagnosis. Each source provides critical information about the disease that might otherwise be absent in other modalities. Combining information from various medical sources boosts confidence in the diagnosis process, enabling the creation of an effective treatment plan for the patient.

Leveraging Shapley Additive Explanations for Feature Selection in Ensemble Models for Diabetes Prediction.

Diabetes, a significant global health crisis, is primarily driven in India by unhealthy diets and sedentary lifestyles, with rapid urbanization amplifying these effects through convenience-oriented living and limited physical activity opportunities, underscoring the need for advanced preventative strategies and technology for effective management. This study integrates Shapley Additive explanations (SHAPs) into ensemble machine learning models to improve the accuracy and efficiency of diabetes predictions. By identifying the most influential features using SHAP, this study examined their role in maintaining high predictive performance while minimizing computational demands.

Detection of Disease Features on Retinal OCT Scans Using RETFound.

Eye diseases such as age-related macular degeneration (AMD) are major causes of irreversible vision loss. Early and accurate detection of these diseases is essential for effective management. Optical coherence tomography (OCT) imaging provides clinicians with in vivo, cross-sectional views of the retina, enabling the identification of key pathological features.

The Use of the Parents' Evaluation of Developmental Status and Developmental Milestones in Screening Children for Developmental Delay in India.

Background/objectives: The Parents' Evaluation of Developmental Status (PEDS) and Developmental Milestones (PEDS:DM) are cost-effective, self-report tools that can be conveniently utilized in low- and middle-income countries to screen for developmental delays in children. This study assessed the diagnostic accuracy of PEDS and PEDS:DM in distinguishing children with typical development (TD) from those with developmental disabilities (DD). It also examined the relationship between parents' general concerns and specific developmental concerns about their children.

Effect of Laser Photobiomodulation on Postoperative Pain After Single-Visit Endodontic Treatment in Children: A Randomized Control Trial.

Background: This study aimed to assess the effectiveness of laser photobiomodulation (PBM) in reducing postoperative pain following single-visit endodontic treatment in children aged 5-9 years.

Methods: Forty children aged 5-9 years with acute irreversible pulpitis in deciduous molars requiring single-visit pulpectomy were included in the study. Pulpectomy was performed according to a standard endodontic protocol.

Myopia in Children: Epidemiology, Genetics, and Emerging Therapies for Treatment and Prevention.

Refractive errors, particularly myopia, are among the most prevalent visual impairments globally, with rising incidence in children and adolescents. This review explores the epidemiology and risk factors associated with the development of refractive errors, focusing on the environmental and lifestyle factors contributing to the current surge in myopia. We provide an overview of key genetic factors and molecular pathways driving the pathogenesis of myopia and other refractive errors, emphasizing the complex interplay between genetic predisposition and environmental triggers.

Nanotherapeutic and Nano-Bio Interface for Regeneration and Healing.

Wound and injury healing processes are intricate and multifaceted, involving a sequence of events from coagulation to scar tissue formation. Effective wound management is crucial for achieving favorable clinical outcomes. Understanding the cellular and molecular mechanisms underlying wound healing, inflammation, and regeneration is essential for developing innovative therapeutics.

The Prognostic Value of Preoperative Total Cholesterol in Surgically Treated Oral Cavity Cancer.

Background: With growing evidence linking lipid profile changes to tumor development and cancer prognosis, we investigated the prognostic significance of preoperative serum total cholesterol (TC) levels in patients with oral cavity squamous cell carcinoma (OSCC) undergoing surgical treatment.

Methods: We conducted a retrospective observational study involving 310 patients with primary OSCC who received surgery at our hospital from January 2009 to December 2018. Receiver operating characteristic curve analysis was performed to determine the optimal preoperative TC cutoff value, with the Youden Index employed as the optimization criterion to maximize the sum of sensitivity and specificity.

Innovative Approaches in Knee Osteoarthritis Treatment: A Comprehensive Review of Bone Marrow-Derived Products.

Knee osteoarthritis (OA) is a chronic articular disease characterized by the progressive degeneration of cartilage and bone tissue, leading to the appearance of subchondral cysts, osteophyte formation, and synovial inflammation. Conventional treatments consist of non-steroidal anti-inflammatory drugs (NSAIDs), analgesics, and glucocorticoids. However, the prolonged use of these drugs causes adverse effects.

Nano-Delivery Revolution: Harnessing Mesenchymal Stem Cell-Derived Exosomes' Potential for Wound Healing.

Stem cell transplantation has proven effective in treating acute and chronic wounds, but its limitations, such as low cellular viability and the need for specialized transportation, highlight the necessity for alternative approaches. This review explores the potential of engineered exosomes, containing identified miRNAs/peptides, as a more stable and efficient cell-free therapy for regenerative medicine, particularly in wound healing. The discussion emphasizes the benefits of exosomes, including their stability, reduced damage, and consistent biological activity, paving the way for innovative applications like lyophilized exosomes, mist spray delivery, and exosome-based scaffolds.

Effectiveness of Bobath Therapy vs. Conventional Medical Gymnastics in Psycho-Social and Cognitive Status Improvement in Children with Mild Neurodevelopmental Delay: A Randomized Double-Blinded Prospective Cohort Study.

The main objective of this research was to compare the Bobath concept and conventional medical gymnastics in psycho-social and cognitive habilitation of infants with mild neurodevelopmental delay, and determine whether there is a difference in their effectiveness. The study included 100 children up to 3 months of age who were diagnosed with a mild neuromotor disorder based on clinical examination, the Münich Functional Developmental Diagnostic Test for the first year of life, and the Ages and Stages questionnaire. The respondents were randomized into two groups, habilitated according to the Bobath concept or conventional medical gymnastics.

Microvascular Metrics on Diabetic Retinopathy Severity: Analysis of Diabetic Eye Images from Real-World Data.

To quantify microvascular lesions in a large real-world data (RWD) set, based on single central retinal fundus images of diabetic eyes from different origins, with the aim of validating its use as a precision tool for classifying diabetic retinopathy (DR) severity. Retrospective meta-analysis across multiple fundus image datasets. The study analyzed 2445 retinal fundus images from diabetic patients across four diverse RWD international datasets, including populations from Spain, India, China and the US.

Coley's Toxin to First Approved Therapeutic Vaccine-A Brief Historical Account in the Progression of Immunobiology-Based Cancer Treatment.

Cancer immunobiology is one of the hot topics of discussion amongst researchers today, and immunotherapeutic modalities are among the selected few emerging approaches to cancer treatment that have exhibited a promising outlook. However, immunotherapy is not a new kid on the block; it has been around for centuries. The origin of cancer immunotherapy in modern medicine can be traced back to the initial reports of spontaneous regression of malignant tumors in some patients following an acute febrile infection, at the turn of the twentieth century.

Cognitive Health Costs of Poor Housing for Women: Exploring Executive Function and Housing Stress in Urban Slums in India.

An increasing body of literature has investigated the implications of housing quality on health, confirming the negative consequences of poor housing quality on physical and mental health. Despite this increased focus on the salutogenic impacts of housing, the relationship between housing quality and cognitive health remains understudied. This study examined how the housing quality in urban informal settlements, where living conditions are often substandard, affects women's cognitive functioning, with a specific focus on executive function (EF) skills.

Assessing Educational Impact of Worldwide Webinar on Management of Myopia Progression in Children.

Objective: To assess the educational impact of a worldwide webinar approach to myopia progression management in children <8 years and 8-12 years old.

Design: Cross-sectional study.

Methods: A self-administered survey was conducted for attendees of a 3 h worldwide webinar held in two parts on consecutive days on the management of myopia progression in children.

Artificial Intelligence Unveils the Unseen: Mapping Novel Lung Patterns in Bronchiectasis via Texture Analysis.

Thin-section CT (TSCT) is currently the most sensitive imaging modality for detecting bronchiectasis. However, conventional TSCT or HRCT may overlook subtle lung involvement such as alveolar and interstitial changes. Artificial Intelligence (AI)-based analysis offers the potential to identify novel information on lung parenchymal involvement that is not easily detectable with traditional imaging techniques.

Periodontitis, Metabolic Syndrome and Diabetes: Identifying Patients at Risk for Three Common Diseases Using the aMMP-8 Rapid Test at the Dentist's Office.

This narrative review paper highlights the multifaceted influence of dysbiotic biofilm, genetic background, host response, and environmental factors on periodontitis. It explores the roles of type I and II diabetes mellitus, gestational diabetes, and metabolic syndrome in the progression of periodontitis, drawing insights from various empirical studies and theoretical perspectives. : Relevant articles were sourced using keywords in databases like PubMed/Medline, Science Direct, Scopus, and Google Scholar.

Prognostic Utility of the Modified Systemic Inflammation Score for Patients Undergoing Oral Cavity Cancer Surgery.

Background/objectives: Chronic inflammation significantly contributes to human malignancies. We investigated the prognostic significance of the preoperative modified systemic inflammation score (mSIS) in patients with primary oral cavity squamous cell carcinoma (OCSCC).

Methods: We retrospectively reviewed data from 320 OCSCC patients who underwent curative surgery between 2007 and 2017.

Efficient Explainable Models for Alzheimer's Disease Classification with Feature Selection and Data Balancing Approach Using Ensemble Learning.

Alzheimer's disease (AD) is a progressive neurodegenerative disorder and is the most common cause of dementia. Early diagnosis of Alzheimer's disease is critical for better management and treatment outcomes, but it remains a challenging task due to the complex nature of the disease. Clinical data, including a range of cognitive, functional, and demographic variables, play a crucial role in Alzheimer's disease classification.

Effect of Nutmeg () and Tea Tree () Essential Oils on the Oxidative and Microbial Stability of Chicken Fillets During Refrigerated Storage.

The current study investigated the impact of nutmeg essential oil (NEO) and tea tree essential oil (TTEO) on the preservation of raw chicken fillets during nine days of refrigerated storage study. The primary aim was to explore the antioxidant and antimicrobial properties of these essential oils (EOs) and assess their ability to extend the shelf life of poultry meat. Gas chromatography-mass spectrometry (GC-MS) was utilized to identify the chemical compositions of NEO and TTEO, revealing the presence of compounds like myristicin and terpenoids, known for their antimicrobial and antioxidant activities.

An Exploration of the Biochemistry of Mustard Seed Meals: A Phytochemical and In Silico Perspective.

The present investigation deals with comparisons drawn among three types of different mustard seed coat colors, namely, Black (), Brown (), and White (), with respect to protein's bio-availability through pepsin digestibility, with and without the involvement of major anti-nutritional factors (glucosinolate type AITC, Allylisothiothiocyanate) and relative food functions. These are validated by means of crude protein determination, precipitated protein isolate preparation for evaluating the fat absorption capacity (FAC), emulsifying activity (EA), emulsion stability (ES), whippability, foam stability (FS), the nitrogen solubility index (NSI), and the protein dispersibility index (PDI). The results indicate that the partial removal of glucosinolates from brown mustard (0.

Recent Trends in Advanced Glycation End Products in Foods: Formation, Toxicity, and Innovative Strategies for Extraction, Detection, and Inhibition.

Advanced glycation end products (AGEs) are produced in foods during their thermal treatment through routes like the Maillard reaction. They have been linked to various health issues such as diabetes, neurodegenerative disorders, and cardiovascular diseases. There are multiple pathways through which AGEs can form in foods and the body.

Nanoencapsulated Essential Oils for Post-Harvest Preservation of Stored Cereals: A Review.

Cereal grains are frequently attacked by microorganisms and insects during storage and processing, which negatively affects their quality, safety, and market value. Therefore, protecting stored grains from microbial contamination is crucial for food industries, farmers, public health associations, and environmental agencies. Due to the negative impact of synthetic gray chemicals, antimicrobial plant-based essential oils (EOs) can serve as alternative, safer, environmentally friendly preservatives that can prolong the shelf life of cereals.