Effect of aluminium toxicity on GI tagged Kachai lemon seedlings.

An experiment was performed to understand the effects of aluminium toxicity (AlCl·6HO) on Kachai lemon growth and development. The toxic effects of aluminium were assessed for 45 days in sand media. With untreated pots serving as the control, seedlings of 1 month old were exposed to three concentrations of AlCl·6HO: 300 μM, 600 μM and 900 μM.

Study of Fibrinogen Albumin Ratio in Type 2 Diabetic Patients and Its Correlation With Diabetic Peripheral Neuropathy.

Background: Type 2 diabetes mellitus (T2DM) is a chronic metabolic disorder that imposes significant complications, including diabetic peripheral neuropathy (DPN). DPN is characterized by marked inflammation, and the fibrinogen-to-albumin ratio (FAR) is one of the new markers for systemic inflammation, it has been used in various diabetic micro- and macro-vascular complications. The present study investigates the association between FAR and nerve conduction abnormalities in T2DM patients with DPN.

A Prospective, Noninterventional Study to Evaluate the Impact of Emicizumab in the Management of Hemophilia A.

Background and objective Hemophilia A (HA) is a genetic bleeding disorder caused by a lack of factor VIII (FVIII) and is associated with frequent bleeding and joint damage. Traditional intravenous treatments for this condition are cumbersome and can lead to complications. Emicizumab, a bispecific monoclonal antibody, offers a promising subcutaneous alternative with potential safety and efficacy-related benefits.

Retrospective Audit of Transfusion Reactions in a Tertiary-Care Hospital in South India.

Background: Blood transfusion is a double-edged sword, as it is a life-saving intervention but is also associated with various adverse reactions. However, blood transfusion safety can be improved by identifying these adverse reactions and taking appropriate interventions. Therefore, in this study, we aimed to determine the frequency and type of transfusion reactions occurring among in-patients at our hospital, as reported to our institute's blood center.

The Appropriate Utilization of Beta-Blockers in Acute Coronary Syndrome Patients: An Improvement Initiative.

Background and objective Beta-blockers are a cornerstone in the management of acute coronary syndrome (ACS), effectively reducing myocardial oxygen demand, preventing recurrent ischemia, and lowering the risk of arrhythmias and reinfarction. Despite several established guidelines, such as those by the American College of Cardiology/American Heart Association (ACC/AHA), advocating their use within 24 hours for eligible patients, beta-blockers remain underutilized in clinical practice. This study aimed to analyze beta-blocker utilization patterns in ACS management and evaluate the impact of targeted improvement initiatives on their appropriate use in eligible ACS patients.

Brucella Endocarditis: A Case Series.

Brucellosis is one of the most common zoonotic infections present worldwide. It usually presents as a febrile illness but can affect multiple organs of the body. Although cardiac involvement in brucellosis is rare, it is a fatal organ involvement.

Robotic Surgery for Benign Hysterectomy: A Real-World Study From India.

Background In gynecology, hysterectomy is a common surgical procedure for benign conditions. This study was conducted to assess the short-term clinical outcomes of robotic-assisted hysterectomy in the Indian population. Methods We performed a retrospective chart review of patients who underwent robotic-assisted benign hysterectomy procedures between December 2021 and July 2024.

Prevalence of Substance Use and Sleep-Related Problems Among Driver Victims Involved in Road Traffic Accidents Presenting to a Tertiary Care Hospital in India.

Background: Road traffic accidents (RTAs) are a critical public health problem leading to significant morbidity, mortality, and socioeconomic losses. Despite known risk factors like substance use and sleep-related problems, there is limited research on the prevalence of these factors among drivers who met with RTAs. Hence, this study aimed to gain insight into the prevalence of substance use and sleep-related problems among this population attending a trauma center in the northern State of India.

Improving agricultural spraying with multi-rotor drones: a technical study on operational parameter optimization.

Drones play a key role in enhancing nutrient management efficiency under climate change scenarios by enabling precise and adaptable spray applications. Current aerial spray application research is primarily focused on examining the influence of drone spraying parameters flight height, travel speed, rotor configuration, droplet size, payload, spray pressure, spray discharge and wind velocity on spray droplet deposition characteristics. The present study aimed to study and optimize the effect of spray height, operating pressure, nozzle spacing and spray nozzle mounting configuration on spray discharge rate, spray width, spray distribution pattern, spray uniformity and spray liquid loss.

Amoebae: beyond pathogens- exploring their benefits and future potential.

Amoebae, fascinatingly diverse protists, showcase a dual nature that positions them as both friends and foes in our world. These organisms, defined by their distinctive pseudopodia, span a spectrum from harmful to helpful. On the darker side, species like pose serious health risks, causing intestinal and liver diseases, while the infamous "brain-eating" leads to fatal primary amoebic meningoencephalitis (PAM), with a daunting 97% mortality rate.

Preparation and Characterization of Carbon Nanodots from turmeric soot for anti-coliform and anti-oral bacterial applications and as anti-staphylococcal coatings.

In an era where chemical synthesis of nanomaterial is accounting for the generation of toxic wastes, leading to nanotoxicity, the present work focuses on the extraction of carbon nanodots from available natural sources such as turmeric smoke. The extracted carbon nanodots were characterized and their physical and chemical attributes were confirmed. The antibacterial property of the isolated carbon nanodots was tested against coliforms and oral bacteria.

Development and assessment of a novel magnetic nanoparticle antibody-conjugate and aptamer-based assay (MNp-Ab-Ap assay) for the rapid diagnosis of pleural tuberculosis.

Pleural tuberculosis (pTB) is a diagnostic challenge because of its non-specific clinical features, lack of accurate diagnostic tools and paucibacillary nature of the disease. We, here describe the development of a novel magnetic nanoparticle antibody-conjugate and aptamer-based assay (MNp-Ab-Ap assay) targeting 4 different (. ) antigens (GlcB, MPT51, MPT64 and CFP-10) for pTB diagnosis.

Development and optimization of dapagliflozin oral nano-bilosomes using response surface method: evaluation, evaluation.

In treating type 2 diabetes, avoiding glucose reabsorption (glucotoxicity) and managing hyperglycemia are also important. A metabolic condition known as diabetes (type-2) is characterized by high blood sugar levels in comparison to normal Bilosomes (BLs) containing Dapagliflozin (Dapa) were formulated, optimized, and tested for oral therapeutic efficacy in the current investigation. Used the Box Behnken design to optimize the Dapa-BLs, formulated via a thin-film hydration technique.

Comparing outcomes of Aquablation versus holmium laser enucleation of prostate in the treatment of benign prostatic hyperplasia: A network meta-analysis.

Introduction: Water Jet Ablation Therapy (WJAT) and Holmium Laser Enucleation of the Prostate (HoLEP) represent two common surgical treatments for Benign Prostatic Hyperplasia (BPH). Despite their increasing use, there is no study between these two methods. We aim to evaluate their efficacy and safety through a network meta-analysis (NMA), providing critical insights for clinical decision-making in the management of moderate to severe lower urinary tract symptoms (LUTS) due to BPH.

F-FDG PET/CT in lymphangiosarcoma: A case report and review of literature.

Objectives: Lymphangiosarcoma is a rare tumor that affects the upper limbs of patients who have undergone breast cancer surgery, including axillary dissection, followed by radiation therapy (RT) to the axilla and has a poor prognosis. F-FDG PET/CT may enable the earlier detection of malignant transformation in a setting of chronic lymphedema and help evaluate the extent and staging of the tumor, allowing earlier initiation of treatment options.

Case Presentation: We herein report a case of cutaneous lymphangiosarcoma in a 47-year-old breast carcinoma patient, which occurred 9 years after initial surgery and radiation therapy.

Synchronous primary tumors amd distant metastasis detected on F-FDG PET in patients with head and neck carcinoma.

Objectives: F-FDG PET/CT has been used to characterize the primary lesion and staging in head and neck cancers (HNC). However, prior studies for detecting distant metastasis and synchronous tumors are sparse, especially in Indian context. To investigate the frequency and distribution of head and neck carcinomas, distant metastases and synchronous malignancies detected in HNC in a north Indian population.

Utility of FDG PET/CT in Sjögren's Syndrome and associated lymphomas; Lymphomagenesis.

Primary Sjögren syndrome (SS) is an autoimmune disease affecting exocrine glands, with predisposition to development of lymphoma (lymphomagenesis). We report a case of Sjogren's syndrome and discuss the role of FDG PET/CT in the primary diagnosis of lymphoma transformation in SS. Furthermore, we reviewed the literature regarding the utility of FDG PET/CT to assess systemic disease activity and also its role in the SS associated lymphoma with light into the new PET tracers that can be explored for these indications in the future.

Rapid detection of cardamom mosaic virus in crude plant extracts using reverse transcription-recombinase polymerase amplification-lateral flow assay (RT-RPA-LFA).

Unlabelled: Cardamom mosaic virus causing mosaic/ disease is the most destructive virus infecting cardamom. The development of effective diagnostic assays is essential for the production of virus-free plants, as the primary spread of the virus occurs through vegetative propagation. Currently used PCR-based assays are not suitable for Point-of-Care testing, require sophisticated equipment, and are time-consuming.

Differentiation ability of hematopoietic stem cells and mesenchymal stem cells isolated from human peripheral blood.

Human hematopoietic stem cells (HSCs) and mesenchymal stem cells (MSCs) are the major stem cells of the bone marrow and are usually isolated from the peripheral blood. In the present study, we isolated these stem cells by an apheresis method from a donor who was administered granulocyte colony-stimulating factor (G-CSF). propagation of these stem cells showed a plastic-adherence property expressing CD73 and CD105 surface markers, which is a characteristic feature of MSCs.

Segregation of Constitutional Isomers of Some Aromatic Amines Exploiting the Changes of Photo-Luminescence Behaviour of Isoreticular Metal-Organic Frameworks.

Three different two dimensional Cd(II)-based metal-organic frameworks (MOFs) have been synthesized by utilizing same N,N'-donor ligand and three different functionalized dicarboxylate linkers namely isophthalate, 5-nitroisophthalate and 5-hydroxyisophthalate for compound 1, 2 and 3 respectively. The compounds that are isoreticular bi-walled 2D frameworks, show dual fluorescence emission spectra for their π-π* and n-π* excitation. Compound 1 is consists of unsubstituted bridging isophthalate whereas 2 and 3 are made with bridging isophthalate that are substituted by electron withdrawing -NO2 group and electron donating -OH group respectively.

Solution-processed MoS2-Expanded Graphite as a Fast-charging Anode for Lithium-ion Batteries.

The widespread demand for battery-powered technologies has propelled the search for efficient and commercially viable electrode materials with fast-charging abilities. Reported herein is an MoS2-expanded graphite (EG) composite as a stable and high-rate lithium-ion battery (LIB) anode, delivering specific capacities of 796 mAh g-1 at 0.5 A g-1 and 320 mAh g-1 at 20 A g-1 over 400 cycles.

Timing of Therapeutic Extractions Can Affect En Masse Anterior Retraction: A Split Mouth Randomized Clinical Trial.

Objective: To investigate the effect of deferred timing of therapeutic extraction on the rate of space closure during en masse anterior retraction.

Methods: Twenty-six patients (aged 16-24 years) with bimaxillary protrusion, crowding <3 mm, requiring bilateral extraction of four first premolars were recruited. Permuted block randomization was done.

Myths and prestige in Hindu nationalist politics.

Sijilmassi et al. offer a myth-based framework that is particularly useful in understanding the rising tide of Hindu nationalism in contemporary India. We propose that the success of these myths lies partly in drawing upon the evolved human capacity for prestige-based status to induce a sense of belonging and identification with high-prestige Hindu social groups.