Understanding ultrasonographic renal length-to-aorta ratio in Sighthounds: A breed specific study in Chippiparai dogs.

Ultrasonographic renal length-to-aorta ratio is an ideal reflection of renal health in dogs. Earlier studies have highlighted the need for breed-specific reference intervals for this parameter. The aim of this study was to establish a breed-specific reference interval of kidney length to aorta ratio (KL:Ao) in Chippiparai dogs, a breed of Indian sighthounds.

Escherichia coli in diarrhoeic lambs: Prevalence, virulence and antibiotic resistance.

The present study aimed to detect the prevalence, virulence and antimicrobial resistance genes profile of Escherichia coli isolated from diarrhoeic lambs. A total of 61 faecal samples were collected from diarrhoeic lambs. The presence of various virulence and antimicrobial resistance genes in E.

In vitro evaluation of frozen thawed kangayam bull semen enriched with antioxidants.

The aim of this study was to assess the in vitro penetration rate of antioxidant enriched frozen thawed Kangayam bull semen. For the current investigation, 5-7-year-old Kangayam bulls were used. The semen was collected twice per week and two ejaculates were collected each time.

C(sp3)-H Bond Functionalization of 8-Methylquinolines.

Quinolines have emerged as essential components in various medicinal agents, playing a key role in treating various ailments. Numerous drugs with a quinoline core have been recognized for their antimalarial, antibacterial, and anticancer activities and have been successfully commercialized, including chloroquine, ciprofloxacin, topotecan, etc. Over the past two decades, we have witnessed a tremendous expansion in the C-H bond functionalization of quinoline scaffolds to widen this chemical space for drug discovery further.

FOXP3 Transcriptionally Activates Fatty Acid Scavenger Receptor CD36 in Tumour-Induced Treg Cells.

The host immune system is adapted in a variety of ways by tumour microenvironment and growing tumour interacts to promote immune escape. One of these adaptations is manipulating the metabolic processes of cells in the tumour microenvironment. The growing tumour aggressively utilise glucose, its primary energy source available in tumour site, and produce lactate by Warburg effect.

The impact of Asian-Indian criteria for higher body mass index and preservative solutions on haemolysis of stored red blood cells: A prospective observational study.

Introduction: The quality of packed red blood cells (PRBC) is influenced by various factors such as the collection and processing method, storage conditions, type of bag materials used, anticoagulant properties, and donor characteristics. Studies have indicated that haemolysis in stored RBC bags is linked to male sex, older age, high haemoglobin count, and increased body mass index (BMI). The study's primary objective was to investigate whether a high BMI, as per Asian Pacific criteria among donors, is associated with an elevated haemolysis rate in stored RBC.

Virulence profiling of Campylobacter spp., C. jejuni and C. fetus subsp. fetus abortions rise in sheep farms in Kashmir, India.

Campylobacter spp. are the leading causes of ovine abortions leading to severe economic losses and a source of bacterial food borne illness in humans, posing a major public health concern. This study reports an increase in Brucella negative abortions in sheep farms in Kashmir, India in the last few years.

Conservation Genetics and Breeding using Molecular Genetic Markers in Japanese Quail ().

Background: The Japanese quail () is a small migratory bird whose main habitats are located in East Asia, Russia, China, Japan, Korea, and India. The Japanese quail was first introduced into the Iraqi research sector in the early 1980s. This investigation aimed to identify the genetic divergence between the available genetic lines of the Japanese quail in Iraq as a first step to conducting further conservation and breeding, benefiting from studying the genetic diversity related to productivity, adaptation, and immune susceptibility.

Amalgamation of Metal Tolerant PGPR sp. EA20 with Birch Wood Biochar Enhanced Growth and Biofortification of Rapeseed under Copper Action.

Background: Amalgamation of metal-tolerant plant growth promoting rhizobacteria (PGPR) with biochar is a promising direction for the development of chemical-free biofertilizers that can mitigate environmental risks, enhance crop productivity and their biological value. The main objective of the work includes the evaluation of the influence of prepared bacterial biofertilizer (BF) on biometric growth parameters as well as physiological and biochemical characteristics of rapeseed ( L.) at copper action.

Role of Hypoxia Induced by Medicinal Plants; A Revolutionary Era of Cellular and Molecular Herbal Medicine in Neuroblastoma Treatment.

As one of the most common solid pediatric cancers, Neuroblastoma (NBL) accounts for 15% of all of the cancer-related mortalities in infants with increasing incidence all around the world. Despite current therapeutic approaches for NBL (radiotherapies, surgeries, and chemotherapies), these approaches could not be beneficial for all of patients with NBL due to their low effectiveness, and some severe side effects. These challenges lead basic medical scientists and clinical specialists toward an optimal medical interventions for clinical management of NBL.

Rapid degradation of pharmaceutical pollutants using poly(1-naphthylamine) decorated BaFeO nanohybrids under microwave irradiation.

Unlabelled: Metformin, a widely used antidiabetic drug, has become a growing concern due to its persistence in the environment. It is one of the most frequently detected pharmaceuticals in wastewater and surface water because it is excreted largely unchanged by patients and is not fully removed in conventional wastewater treatment plants. The present study focuses on the synthesis and characterization of BaFeO/poly(1-naphthylamine) (PNA) nanohybrids and their application as microwave-active catalysts for the degradation of metformin.

Medial and Lateral Meniscus Root Tear: Etiopathogenesis and Morphological Pattern in Indian Population.

Objective: This study aims to enhance our understanding of the morphological pattern, causes and pathogenesis of meniscal root injuries in the Indian population.

Materials And Methods: Sixty-four patients with meniscus root tears were included in the study. The patients were categorized into two groups based on the location of the meniscus tear: Group 1 ( = 41) comprised patients with lateral meniscus root injury (LMRI), and Group 2 ( = 23) included patients with medial meniscus root injury (MMRI).

Correction: Atypical Multi-ligamentous Knee Injury (aMLKI): Binary Injury with Avulsion of One Cruciate and Tear of the Other, or Bi-cruciates Avulsion with or Without Collateral Ligament Injury Following Road Traffic Accidents (RTA).

[This corrects the article DOI: 10.1007/s43465-024-01256-7.].

Dual-Mobility Total Hip Arthroplasty in Patients with Obesity, Morbid Obesity and Super-Obesity: Medium-Term Outcomes of a Series of 180 Hips.

Background: Obesity has been consistently proven to be associated with an increased risk of dislocation following total hip arthroplasty (THA). As the prevalence of obesity continues to rise globally, it is of vital importance to minimise risks, including dislocation rates, in these patients undergoing THA.

Methods: We describe a series of patients with obesity, morbid obesity (BMI ≥ 40) and super-obesity (BMI ≥ 50) undergoing THA at our institution over a 10-year period using a dual-mobility acetabular cup.

Outcomes of All-Inside Arthroscopic ACL Reconstruction with Lateral Extra-Articular Tenodesis (ACLR + LET).

Background: Anatomic single-bundle ACL reconstruction (ACLR) produces good results when the graft and tunnel are positioned in the anatomic footprint on the femoral and tibial insertion sites in a more oblique orientation. The of the knee and its biomechanical role in controlling rotational laxity, internal rotation, and pivot shift has led to adding adjunctive procedures like extra-articular augmentation and lateral extra-articular tenodesis (LET) to decrease rotational laxity. We prospectively analyzed young adults with rotational instability and generalized laxity undergoing an arthroscopic single bundle ACLR with an additional LET procedure.

Correction: A Radiological Comparison of Robotic-Assisted Versus Manual Techniques in Total Hip Arthroplasty.

[This corrects the article DOI: 10.1007/s43465-024-01232-1.].

Bone and Joint Involvement in Beta Thalassemic Patients: A Cross-sectional Study.

Purpose: There is paucity of guidelines with inadequate data available about the extent and prevention of bone and joint disease in beta-thalassemic patients in Indian population. This study aims to determine bone and joint involvement in beta-thalassemic patients. It evaluates serum biochemical parameters of bone formation and resorption and correlates with the symptomatology in these patients.

Do Ultracongruent Inserts Reproduce the Intraoperative Sagittal Plane Kinematics of Posterior Stabilized TKR? Assessment Using a Modern Robotic System.

Background: Ultracongruent (UC) total knee replacement (TKR) designs, serving as alternatives to posterior stabilized (PS) and cruciate retaining (CR) designs, lack conclusive evidence regarding posterior femoral rollback. This study aimed to compare intraoperative posterior femoral rollback and maximal knee flexion between UC and PS inserts, addressing the paucity of literature on femoral rollback achieved with UC designs in total knee replacement.

Methods: A consecutive cohort of 20 patients undergoing robotic-assisted primary total knee replacement, posterior femoral rollback and maximal intraoperative knee flexion were assessed.

Effect of Approach Based Lumbar Interbody Fusion on Sagittal Spinopelvic Parameters and Functional Outcomes: Comparison between Oblique Lumbar Interbody Fusion (OLIF) and Transforaminal Lumbar Interbody Fusion (TLIF).

Purpose: Transforaminal lumbar interbody fusion (TLIF) and oblique lumbar interbody fusion (OLIF) are the most commonly conducted operations for interbody fusions. In addition to fusion, the restoration of proper spinal alignment has become crucial for achieving favorable functional outcomes. There is a lack of agreement on which lumbar interbody fusion technique provides the most effective correction for sagittal spinopelvic parameters (SSPs).

Ultrasound as a Diagnostic Modality in Hand and Wrist Musculoskeletal Pathologies: A Narrative Review.

Background: Musculoskeletal ultrasonography of the hand and wrist is becoming the trend in assessing and diagnosing most hand and wrist injuries, soft-tissue mass, and occult fractures. Its advantages include ultra-high frequency probes, noninvasiveness, cost-effectiveness, lack of ionising radiation, and portability. The patients are comfortable doing this procedure in the outpatient department, and visualising the ultrasound images increases their confidence.

Comparison of Clinical and Patient Reported Outcomes in One-Sided Cruciate-Retaining Versus Other-Sided Posterior Stabilizing Protheses in Bilateral Simultaneous Total Knee Arthroplasty.

Introduction: Cruciate retaining and posterior stabilizing knee systems are frequently used in total knee replacements. Most researchers compare the results of Cruciate Retaining (CR) and Posterior Stabilizing (PS) knees with those of a control group. The results of using both knee systems in a single patient in simultaneous Total Knee Arthroplasty (TKA) have been studied less.

Obese Patients Do Not Benefit from Bone Marrow Aspiration Concentrate Injection for Knee Osteoarthritis: A Prospective Cohort Study of 68 Patients.

Background: Bone marrow aspirate concentrate (BMAC) is considered one of the biological treatments for knee osteoarthritis (KOA). Patient selection remains a key factor to ensure that optimal treatment benefit and body mass index (BMI) are one of the key factors to be considered. This study aims to evaluate the influence of obesity on the duration of treatment benefit of BMAC for KOA.

Functional Outcomes of Nuts-in-Jelly Mosaicplasty.

Introduction: Interspace defects after osteochondral autograft transfer (OATS) are filled only with fibrocartilage. Attempts have been made to address these issues in OATS with procedures like mega OATS and Hexagonal Osteochondral Graft System. We have described the functional outcomes of a hybrid technique combining a regeneration and a restoration modality to address the interspace defect in OATS.

The Molecular Detection and Therapeutic Management of Pathogenic Infection in a Goat: A Case Report.

A 2-year-old female Assam Hill goat was presented with a clinical history of anorexia, fever, mild anemia, rough body coat, dehydration, tachycardia, dyspnea and swelling of palpable lymph nodes. Hematology revealed low hemoglobin, packed cell volume, red blood cell and thrombocyte count. Biochemical analysis showed increased serum concentration of alanine aminotransferase (ALT), aspartate aminotransferase (AST), creatinine and urea in comparison to the normal reference range.