2 results match your criteria: "Independent Public Hospital No. 4 in Lublin[Affiliation]"
Musculoskeletal involvement in systemic sclerosis.
Reumatologia
August 2024
Department of Rheumatology and Systemic Connective Tissue Diseases, Independent Public Hospital No. 4 in Lublin, Poland.
Article Synopsis
- Systemic sclerosis (SSc) is a serious connective tissue disease affecting multiple organs, including the lungs, heart, and musculoskeletal system, with musculoskeletal involvement occurring in 40-90% of patients.
- Common symptoms include joint pain, arthritis, and issues such as tendon rupture and calcinosis, which negatively impact the quality of life and can lead to disabilities.
- Understanding the causes of these musculoskeletal issues could help develop new treatments, improving patient outcomes and reducing complications.
Key Regulators of Angiogenesis and Inflammation Are Dysregulated in Patients with Varicose Veins.
Int J Mol Sci
June 2024
Chair and Department of Biology and Genetics, Medical University of Lublin, 4a Chodźki St., 20-093 Lublin, Poland.
Varicose veins (VVs) are the most common manifestation of chronic venous disease (CVD) and appear as abnormally enlarged and tortuous superficial veins. VVs result from functional abnormalities in the venous circulation of the lower extremities, such as venous hypertension, venous valve incompetence, and venous reflux. Previous studies indicate that enhanced angiogenesis and inflammation contribute to the progression and onset of VVs; however, dysregulations in signaling pathways associated with these processes in VVs patients are poorly understood.
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