The Life and Work of Prof. Dr. Antapur Venkoba Rao: The Enduring Legacy of an Innovative Mind.

Dr. Antapur Venkoba Rao, born on August 20, 1927, in Andhra Pradesh, was a pioneering figure in Indian psychiatry, often recognized as the "Father of Indian Psychiatry" and the "Father of Geriatric Mental Health." His exceptional academic achievements led him to specialize in psychiatry, where he made substantial contributions, particularly in the study of depressive disorders.

Comparison of Auditory Perception Scores Following Unilateral Cochlear Implantation in Children From Different Regions Using Neubio's Full-Spectrum Continuous Stimulation.

Aims And Objectives: The study aimed to compare the auditory perception status of children from different socioeconomic backgrounds, specifically urban versus rural. It also examined the correlation between outcome measures and the frequency of auditory verbal therapy sessions attended, as well as the impact of continuous electric analog stimulation on the age of implantation.

Material And Methods: A retrospective cohort study was carried out on 30 children who have received unilateral cochlear implantation in rural versus urban backgrounds.

Establishing the Cut-Off Values of 17-Hydroxyprogesterone for Diagnosing Congenital Adrenal Hyperplasia: A Prospective Observational Study in a Tertiary Care Hospital.

Introduction Congenital adrenal hyperplasia (CAH) is an autosomal recessive disorder primarily caused by 21-hydroxylase enzyme deficiency, impairing cortisol synthesis and resulting in elevated androgen levels. CAH presents in two classical forms: salt-wasting (SW) and simple virilizing (SV). Although CAH is rare in India, regional variations and the absence of a national newborn screening (NBS) program pose significant challenges to accurate diagnosis.

Antimicrobial Efficacy of Ampicillin With Ceftriaxone in Comparison With Diclofenac Sodium, Modified Triple Antibiotic Paste, and Calcium Hydroxide Against Enterococcus faecalis: An In-Vitro Study.

Objective This in vitro study aimed to assess and compare the antimicrobial effectiveness of ampicillin with ceftriaxone (AC), diclofenac sodium (DS), modified triple antibiotic paste (MTAP), and calcium hydroxide (CH) against in root canal systems. Materials and methods The antimicrobial activity of the medicaments was assessed by determining the minimum inhibitory concentrations (MIC) via the agar well diffusion method. A total of 40 extracted permanent teeth underwent root canal treatment, and was introduced into the canal preparations.

Linear Accelerator (LINAC) Radiosurgical Management of Brain Arteriovenous Malformations: An Experience From a Tertiary Care Center.

Introduction: Brain arteriovenous malformations (AVM) are complex vascular pathologies with a significant risk of hemorrhage. Stereotactic radiosurgery (SRS) is an effective treatment modality for AVM, initially popularized on the Gamma Knife (Elekta AB, Stockholm, Sweden) platform, and now benefits from the modern advances in linear accelerator (LINAC)-based platforms. This study evaluates the outcomes of LINAC-based SRS/hypofractionated stereotactic radiotherapy (hFSRT) for cerebral AVMs.

The Diagnostic Efficacy of Flexible Fiberoptic Laryngoscopy and Its Correlation With Histopathology in Different Benign Lesions of the Vocal Cord in a Tertiary Care Hospital: A Prospective Clinical Study.

Introduction Benign vocal cord lesions are diagnosed by clinical examination with usually an office-based laryngoscopy examination. The severity of voice impairment can be assessed by severity scores such as the Voice Handicap Index (VHI). These lesions are usually treated by conservative methods such as voice rest/restriction and voice therapy.

Zebrafish: A Cost-Effective Model for Enhanced Forensic Toxicology Capabilities in Low- and Middle-Income Countries.

Low- and middle-income countries (LMICs) are increasingly challenged by the rising burden of medicolegal cases. Traditional forensic infrastructure and in vivo rodent models often have significant limitations due to high costs and ethical concerns. As a result, zebrafish () are gaining popularity as an attractive alternative model for LMICs because of their cost-effectiveness and practical advantages.

Development of the AIIMS Bhopal Pre-sternal Keloid Scale (ABPSKS): A Tool for Assessing Severity and Comparing Treatment Outcomes.

Pre-sternal keloids are a distinct clinicopathological entity differing in many ways from keloids occurring elsewhere, as there are differences in pathogenesis, clinical presentation, and management. We have reviewed commonly used assessment scales like the Vancouver Scar Scale, the Patient and Observer Scar Assessment Scale, and the Detroit Keloid Scale and identified some shortcomings in applying them in assessing pre-sternal keloids. Therefore, we developed the AIIMS Bhopal pre-sternal keloid scale (ABPSKS), a pre-sternal keloid-specific tool to enable the assessment of the severity of the disease, the efficacy of treatment, and the comparison of outcomes of different treatment modalities.

A Study of the Comparison Between Preoperative Ultrasonography Findings With Intraoperative Observations in Laparoscopic Cholecystectomy.

Aim: This study aims to evaluate the accuracy of ultrasonography (US) by comparing preoperative ultrasonographic findings with intraoperative observations during laparoscopic cholecystectomy (LC).

Materials And Methods: An observational analytical study was conducted at a tertiary hospital in Pune over two years and included 98 patients aged 20-80 with symptomatic cholelithiasis confirmed by US. Preoperative parameters assessed included gallstone number, gallbladder volume, wall thickness, and pericholecystic fluid.

Surgical Outcomes of Unilateral Biportal Endoscopy Versus Full Endoscopy for Lumbar Canal Stenosis: A Meta-Analysis.

Lumbar canal stenosis (LCS) is a common cause of chronic lower back pain in the elderly. Traditionally, open decompression surgery has a prolonged recovery, higher blood loss, and more complications. As a result, there remains no clear consensus on which of these minimally invasive spine surgery (MISS) techniques, including unilateral biportal endoscopy (UBE) and full endoscopy (FE), is the optimal technique for LCS treatment.

Chronic Leg Swelling: Uncovering a Rare Hydatid Cyst.

Hydatidosis is an infection caused by the helminth . The liver and lungs are the most frequently affected organs, primarily due to their roles in filtering blood. Primary hydatidosis of the skeletal muscles is an exceedingly rare condition, often asymptomatic, which can lead to its misdiagnosis as a more common soft tissue tumour.

Mental and Oral Health: A Dual Frontier in Healthcare Integration and Prevention.

Mental and oral health are interrelated, and problems in one area usually affect the other. This review discusses the complex relationships between oral and mental health, particularly the psychosocial challenges faced by individuals with mental health disorders in maintaining oral hygiene, including stigma, lack of access to care, and financial barriers. It also discusses how psychiatric conditions influence oral health, with regard to issues such as dry mouth, gum disease, and tooth decay, and how poor oral health can aggravate mental well-being.

Persistent Thrombocytopenia of an Unexplained Cause in a Patient With Metastatic Renal Cell Carcinoma: A Case Report.

Thrombocytopenia is a common complication in patients with solid tumors, particularly renal cell carcinoma (RCC), arising from mechanisms such as chemotherapy, direct tumor invasion, and paraneoplastic syndromes. Managing thrombocytopenia in advanced cancer presents significant challenges, often limiting therapeutic options and impacting patient outcomes. This case report describes a 62-year-old man with metastatic RCC complicated by persistent thrombocytopenia, unresponsive to both conventional treatments and novel therapies.

Association of workplace toilet access with urinary tract symptoms and productivity loss among female workers.

This study investigated workplace toilet access related to lower urinary tract symptoms (LUTS) among women in the Korean workforce. A cross-sectional survey was conducted to determine demographic characteristics, occupational risk factors, and urinary tract symptoms among employed Korean women. Occupational risk factors included two survey questions about access to toilets at work.

Formulation, Characterization and in vitro Release of Topical Nanoemulsion Containing Prednisolone-Derived Corticosteroid.

Backround: Prednisolone-Derived Corticosteroid (PDC), has anti-inflammatory activity in ocular administration. However, drug administration to the eye is extremely difficult due to the complex structure of the eye. Because of the ability of the eye to retain the drug and its physiology, the bioavailability of drugs applied to the eye is very low.

From Sevagram to National Health Policy: Dr. Sushila Nayar's Contributions to Rural Healthcare and Medical Education in India.

Dr. Sushila Nayar (1914-2001) was a pioneering figure in Indian public health whose work spanned from grassroots initiatives to national policy formation. This review article traces Dr.

Role of Artificial Intelligence in MRI-Based Rectal Cancer Staging: A Systematic Review.

Several studies explored the application of artificial intelligence (AI) in magnetic resonance imaging (MRI)-based rectal cancer (RC) staging, but a comprehensive evaluation remains lacking. This systematic review aims to review the performance of AI models in MRI-based RC staging. PubMed and Embase were searched from the inception of the database till October 2024 without any language and year restrictions.

Navigating Challenges in Adult Airway Foreign Body Extraction: Retrospective Insights From Flexible Bronchoscopy.

Background Airway foreign body aspiration is an emergency predominantly observed in children and the elderly. However, it also occurs in adults, presenting with a variety of symptoms. Both rigid and flexible bronchoscopies are employed for foreign body retrieval.

A Comparative Study of ChatGPT and BingAI in Answering the National Eligibility Entrance Test for Postgraduates (NEET-PG)-Style Practice Questions: A Cross-Sectional Analysis.

Purpose: The integration of artificial intelligence (AI) into medical education has witnessed significant progress, particularly in the domain of language models. This study focuses on assessing the performance of two notable language models, ChatGPT and BingAI Precise, in answering the National Eligibility Entrance Test for Postgraduates (NEET-PG)-style practice questions, simulating medical exam formats.

Methods: A cross-sectional study conducted in June 2023 involved assessing ChatGPT and BingAI Precise using three sets of NEET-PG practice exams, comprising 200 questions each.

Dasatinib-Induced Gynecomastia: A Case Report.

Gynecomastia, the abnormal enlargement of male breast tissue, is a rare side effect associated with dasatinib. This drug is used in the treatment of chronic myeloid leukemia (CML). We present a case of dasatinib-induced gynecomastia in a 52-year-old gentleman with CML who developed bilateral breast enlargement and tenderness after approximately four months of dasatinib treatment.

Bibliometric Insights Into Thromboelastography Research Using PubMed and VOSviewer.

Thromboelastography (TEG) has evolved from a primarily surgical tool to a key instrument in broader medical fields, including personalized medicine for coagulopathies. The rationale for conducting this bibliometric analysis of TEG is to understand the evolution and current state of research in this critical field. By identifying publication trends, key contributors, and major developments, this study aims to provide valuable insights to guide future research and clinical practices in TEG.

An Unusual Case Report of Duodenojejunal Flexure Tumor With a Systematic Review of the Literature.

The small intestine is the longest segment of the gastrointestinal (GI) tract, but cancers in the small intestine are infrequent. The duodenojejunal (DJ) flexure is an uncommon site for tumors, and those located in these sites are difficult to identify and manage properly. Their rarity, along with ambiguous symptoms that can be readily misattributed to milder conditions, results in a delayed diagnosis when the tumors have significantly advanced.

Factors Affecting Visual Outcomes Following Scleral-Fixated Intraocular Lens Implantation at a Tertiary Care Center in Eastern India.

Background: Lens implantation becomes a major concern in patients lacking posterior capsular support, but various methods are available for rehabilitation. In such patients, scleral-fixated intraocular lens (SFIOL) implantation is preferred due to its fewer complications and better simulation of the natural lens position. In this non-randomized retrospective clinical study, we aimed to assess visual outcomes after sutureless SFIOL implantation in aphakic patients and factors affecting visual outcomes.

Assessment and Correlation of TP53 With Histological Parameters of Oral Squamous Cell Carcinoma.

Background Oral squamous cell carcinoma is a common problem among tobacco chewers and related products in developing countries like India. Histopathological examination evaluates and confirms the diagnosis of oral SCC. Clinical examination and molecular profiling by histopathological examination (HPE) are important prognostic tools used in clinical practice.

Evaluating the Effectiveness of a Comprehensive Interventional Package on the Quality of Life of Children With Asthma.

Introduction: Asthma is a chronic lung disease that negatively affects children's quality of life (QoL). Improving QoL is a key outcome in managing children with asthma.

Objectives: The objective of the study was to evaluate the effectiveness of a comprehensive interventional package on QoL among asthmatic children attending an asthma clinic at a selected hospital.