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Impetigo Publications | LitMetric

2,356 results match your criteria: "Impetigo"

Cutaneous leishmaniasis incidence has been rising in the past couple of decades. Standard therapy often includes antileishmanial drugs; however, due to their low safety and toxicity threshold, alternative treatments are being investigated. The association between COVID-19 and cutaneous leishmaniasis remains unclear and exploring this connection may offer crucial insights into the pathophysiology of and treatment strategies for infected patients.

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Bullous impetigo leading to streptococcal toxic shock syndrome (STSS) immune activation and massive cytokine release is a rare condition. It has a significant mortality rate, which calls for quick diagnosis, early suspicion, and integrated treatment. Herein, we discuss the case of a 66-year-old man who underwent evaluation for leg swelling before quickly going into shock and experiencing respiratory failure, which necessitated invasive mechanical intubation.

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is a newly identified pathogen that causes respiratory tract infections, skin infections, such as cellulitis, abscesses, and impetigo, and currently, there is no licensed vaccine available against it. To develop a vaccine against , a bacterial pan-genome analysis was applied to identify potential vaccine candidates. A total of 4908 core proteins were retrieved and utilized for identifying four proteins, including SG38 Panton-Valentine leukocidin LukS-PV protein, SG62 staphylococcal enterotoxin type A protein, SG39 enterotoxin B protein, and SG43 enterotoxin type C3 protein as potential vaccine candidates.

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(Group A Streptococcus, GAS) bacteria cause a spectrum of human diseases ranging from self-limiting pharyngitis and mild, uncomplicated skin infections (impetigo, erysipelas, and cellulitis) to highly morbid and rapidly invasive, life-threatening infections such as streptococcal toxic shock syndrome and necrotizing fasciitis (NF). HLA class II allelic polymorphisms are linked with differential outcomes and severity of GAS infections. The dysregulated immune response and peripheral cytokine storm elicited due to invasive GAS infections increase the risk for toxic shock and multiple organ failure in genetically susceptible individuals.

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Managing the deteriorating child with suspected group A infection.

Nurs Child Young People

November 2023

Birmingham Women's and Children's NHS Foundation Trust, Birmingham, England.

Group A Streptococcus bacteria can cause various pyogenic infections such as tonsillitis, pharyngitis, scarlet fever, impetigo, erysipelas, cellulitis and pneumonia. Most group A Streptococcus infections in children are mild and respond positively to treatment with antibiotics. However, some children develop severe infection accompanied by complications such as sepsis and will require urgent treatment, which may include non-invasive or invasive ventilation and the administration of fluids and vasoactive agents.

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Article Synopsis
  • - A 10-year-old boy in Hokkaido, Japan, was diagnosed with severe infections caused by PVL-positive MRSA, leading to complications like osteomyelitis and pulmonary embolism.
  • - The treatment involved multiple antibiotics, including linezolid and vancomycin, and required surgical interventions due to additional abscesses and septic arthritis.
  • - Family members also showed signs of infection from the same MRSA strain, indicating its spread, and it was identified as a genetic variant of the USA300 clone, suggesting its emergence in Japan.
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A STUDY OF SKIN SEPSIS AMONGST ABATTOIR WORKERS IN MONIYA, IBADAN, OYO STATE, NIGERIA.

Ann Ib Postgrad Med

June 2023

Department of Pharmaceutical Microbiology, Faculty of Pharmacy, University of Ibadan, Ibadan Nigeria.

Background: Skin sepsis is a pyodermal infection caused by Lancefield's group streptococci and . It is characterized by discolored and mottled skin, cellulitis, impetigo and multi-systemic collagen muscularitis and can be transmitted from person to person.

Objective: This study sampled the skin of consented abattoir workers in Moniya Ibadan, for clinical sepsis, with a view to establishing a causal relationship between the infection obtained and the abattoir workers examined.

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Background: While there are many skin infections, reducing the burden of scabies and impetigo for remote living Aboriginal people, particularly children remains challenging. Aboriginal children living in remote communities have experienced the highest reported rate of impetigo in the world and are 15 times more likely to be admitted to hospital with a skin infection compared to non-Aboriginal children. Untreated impetigo can develop into serious disease and may contribute to the development of acute rheumatic fever (ARF) and rheumatic heart disease (RHD).

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Persistence of the Staphylococcus aureus epidemic European fusidic acid-resistant impetigo clone (EEFIC) in Belgium.

J Antimicrob Chemother

August 2023

Department of Microbiology, LHUB-ULB, National Reference Centre for Staphylococcus aureus and other species, Université libre de Bruxelles, route de Lennik 808, 1070 Brussels, Belgium.

Objectives: In August 2018, a public health alert was issued in Belgium regarding clusters of impetigo cases caused by the epidemic European fusidic acid-resistant impetigo clone (EEFIC) of Staphylococcus aureus. As a result, the Belgian national reference centre (NRC) was commissioned to update the epidemiology of S. aureus causing community-onset skin and soft tissues infection (CO-SSTI) to assess the proportion of EEFIC among them.

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Pustular psoriasis: A distinct aetiopathogenic and clinical entity.

Indian J Dermatol Venereol Leprol

January 2024

Department of Dermatology, Armed Forces Medical College (AFMC), Wanowarie, Pune, India.

Pustular psoriasis is a distinct subset of psoriasis that presents with involvement of the skin in the form of sterile pustules along with systemic manifestations. Though it has been conventionally grouped under the umbrella of psoriasis, recent research has shed light on its pathogenetic mechanisms associated with the IL-36 pathway, which is distinct from conventional psoriasis. Pustular psoriasis in itself is a heterogeneous entity consisting of various subtypes, including generalised, localised, acute, and chronic forms.

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The World Health Organization published the preferred product characteristics for a Group A Streptococcus (Strep A) vaccine in 2018. Based on these parameters for the age of vaccination, vaccine efficacy, duration of protection from vaccine-derived immunity, and vaccination coverage, we developed a static cohort model to estimate the projected health impact of Strep A vaccination at the global, regional, and national levels and by country-income category. We used the model to analyse six strategic scenarios.

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Article Synopsis
  • Atopic dermatitis (AD) is a widespread skin condition in Australia that impacts people from various backgrounds, causing significant physical and emotional challenges.
  • There is a lack of research specifically addressing AD in individuals with skin of color, particularly among First Nations Peoples and recent immigrants.
  • Future studies need to focus on understanding AD's prevalence and its management in marginalized communities, to address healthcare inequalities and improve outcomes for disadvantaged groups.
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Introduction: The incidences of acute rheumatic fever (ARF) and rheumatic heart disease (RHD), which were leading causes of death in children in the 1920s, have decreased substantially. Considering the recent resurgence of scarlet fever and increased incidence of streptococcal pharyngitis in children, an investigation of the current status of ARF and RHD may be worthwhile.

Objective: To summarize the prevalence trends, pathogenic factors, and prevention strategies for ARF and RHD in children.

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Methods to Analyze the Contribution of Complement Evasion Factor (CEF) to Streptococcus pyogenes Virulence.

Methods Mol Biol

June 2023

Department of Molecular Medicine & Pathology, School of Medical Sciences and Maurice Wilkins Centre for Biomolecular Discovery, The University of Auckland, Auckland, New Zealand.

Group A Streptococcus (GAS, Streptococcus pyogenes) is an exclusively human pathogen that causes a range of diseases, including pharyngitis, tonsillitis, impetigo, erysipelas, necrotizing fasciitis, and toxic shock syndrome. Post-streptococcal sequelae include acute rheumatic fever and rheumatic heart disease. The bacterium produces a large arsenal of virulence factors that contribute to host tissue adhesion/colonization, bacterial spread, and host immune evasion.

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BACKGROUND Leukocytoclastic vasculitis is a small-vessel vasculitis associated with infections, autoimmune disorders, and certain drugs, but it may also be idiopathic. CASE REPORT We report the case of a 37-year-old woman with no significant past medical history who presented with a chief concern of a full-body rash. Before the rash appeared, she had been treated for group A Streptococcus with amoxicillin and prednisone.

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Evaluating the role of asymptomatic throat carriage of Streptococcus pyogenes in impetigo transmission in remote Aboriginal communities in Northern Territory, Australia: a retrospective genomic analysis.

Lancet Microbe

July 2023

Department of Infectious Diseases, University of Melbourne, Melbourne, VIC Australia; Victorian Infectious Diseases Service, The Royal Melbourne Hospital, Melbourne, at the Peter Doherty Institute for Infection and Immunity VIC, Australia; Global and Tropical Healthy Division, Menzies School of Health Research, Charles Darwin University, Darwin, NT, Australia. Electronic address:

Article Synopsis
  • Streptococcus pyogenes (GAS) infections significantly impact Aboriginal Australians, leading to skin infections and serious health issues like rheumatic heart disease, but understanding their transmission has been challenging.
  • A genomic analysis of GAS isolates from a study on impetigo in remote Northern Territory communities revealed that asymptomatic throat carriage plays a larger role in GAS transmission compared to impetigo lesions.
  • Findings indicated households experienced prolonged GAS infections, often reinforced by factors like household size and the presence of other infections, complicating efforts to control these infections.
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Background: Integrated programmes that use combination mass drug administration (MDA) might improve control of multiple neglected tropical diseases simultaneously. We investigated the impact of Timor-Leste's national ivermectin, diethylcarbamazine citrate, and albendazole MDA, for lymphatic filariasis elimination and soil-transmitted helminth (STH) control, on scabies, impetigo, and STH infections.

Methods: We did a before-after study in six primary schools across three municipalities in Timor-Leste (urban [Dili], semi-urban [Ermera], and rural [Manufahi]) before (April 23 to May 11, 2019) and 18 months after (Nov 9 to Nov 27, 2020) MDA delivery between May 17 and June 1, 2019.

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The differential diagnosis of vesiculobullous lesions can be intimidating to the primary care provider. While some entities such as bullous impetigo may easily be diagnosed clinically if the patient's demographics as well as the lesion morphology and distribution present classically, atypical presentations may require additional laboratory studies for confirmation. We describe a case of bullous impetigo with characteristics that clinically mimicked two rare immunobullous dermatoses.

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Considering the lack of existing evidence on economic burden for diseases caused by group A Streptococcus, we estimated the economic burden per episode for selected diseases. Each cost component of direct medical costs (DMCs), direct non-medical costs (DNMCs), and indirect costs (ICs) was separately extrapolated and aggregated to estimate the economic burden per episode by income group as classified by the World Bank. Adjustment factors for DMC and DNMC were generated to overcome related data insufficiencies.

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Article Synopsis
  • The study explored atopic dermatitis (AD), a chronic skin condition, to link its severity with historical and clinical features as well as biomarkers.
  • A total of 2,862 participants were categorized into mild, moderate, and severe AD, with findings showing that severity is associated with several factors including a personal/family history of allergic disorders and certain skin conditions.
  • Key indicators of severity included high serum IgE levels, eosinophilia, and specific skin manifestations, along with a range of bacterial and viral skin infections, highlighting the complex nature of AD.
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Impetigo herpetiformis (IH) is a pregnancy-specific dermatosis that is currently considered a form of generalised pustular psoriasis and mainly occurs in late pregnancy during the third trimester. IH presents as erythematous patches and pustules and might have systemic involvement. The disease may be associated with severe maternal, fetal, and neonatal complications.

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Higher Rates of Hospitalizations among Pediatric Refugees than Local Population Attending the Emergency Department and Longer In-patient Stay.

Isr Med Assoc J

April 2023

Department of Pediatrics, Adams Children's Hospital, Wolfson Medical Center, Holon, Israel, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

Background: The global refugee crises have raised concerns among medical communities worldwide; nonetheless, access to healthcare has rarely been studied even though refugees are a medically high-risk group.

Objectives: To compare pediatric department admission rates from the pediatric emergency department (PED) of refugees and Israelis.

Methods: We compared data from refugee and Israeli children admitted to the pediatric department at Wolfson Medical Center in Israel between 2013-2017.

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