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2,356 results match your criteria: "Impetigo"
Trop Med Infect Dis
September 2023
College of Medicine, King Saud University, Riyadh 11472, Saudi Arabia.
Cutaneous leishmaniasis incidence has been rising in the past couple of decades. Standard therapy often includes antileishmanial drugs; however, due to their low safety and toxicity threshold, alternative treatments are being investigated. The association between COVID-19 and cutaneous leishmaniasis remains unclear and exploring this connection may offer crucial insights into the pathophysiology of and treatment strategies for infected patients.
View Article and Find Full Text PDFCureus
August 2023
Pathology, One Brooklyn Health, New York, USA.
Bullous impetigo leading to streptococcal toxic shock syndrome (STSS) immune activation and massive cytokine release is a rare condition. It has a significant mortality rate, which calls for quick diagnosis, early suspicion, and integrated treatment. Herein, we discuss the case of a 66-year-old man who underwent evaluation for leg swelling before quickly going into shock and experiencing respiratory failure, which necessitated invasive mechanical intubation.
View Article and Find Full Text PDFJ Biomol Struct Dyn
November 2024
Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.
is a newly identified pathogen that causes respiratory tract infections, skin infections, such as cellulitis, abscesses, and impetigo, and currently, there is no licensed vaccine available against it. To develop a vaccine against , a bacterial pan-genome analysis was applied to identify potential vaccine candidates. A total of 4908 core proteins were retrieved and utilized for identifying four proteins, including SG38 Panton-Valentine leukocidin LukS-PV protein, SG62 staphylococcal enterotoxin type A protein, SG39 enterotoxin B protein, and SG43 enterotoxin type C3 protein as potential vaccine candidates.
View Article and Find Full Text PDFPathogens
July 2023
Department of Biomedical Sciences, University of North Dakota, Grand Forks, ND 58202, USA.
(Group A Streptococcus, GAS) bacteria cause a spectrum of human diseases ranging from self-limiting pharyngitis and mild, uncomplicated skin infections (impetigo, erysipelas, and cellulitis) to highly morbid and rapidly invasive, life-threatening infections such as streptococcal toxic shock syndrome and necrotizing fasciitis (NF). HLA class II allelic polymorphisms are linked with differential outcomes and severity of GAS infections. The dysregulated immune response and peripheral cytokine storm elicited due to invasive GAS infections increase the risk for toxic shock and multiple organ failure in genetically susceptible individuals.
View Article and Find Full Text PDFNurs Child Young People
November 2023
Birmingham Women's and Children's NHS Foundation Trust, Birmingham, England.
Group A Streptococcus bacteria can cause various pyogenic infections such as tonsillitis, pharyngitis, scarlet fever, impetigo, erysipelas, cellulitis and pneumonia. Most group A Streptococcus infections in children are mild and respond positively to treatment with antibiotics. However, some children develop severe infection accompanied by complications such as sepsis and will require urgent treatment, which may include non-invasive or invasive ventilation and the administration of fluids and vasoactive agents.
View Article and Find Full Text PDFIJID Reg
September 2023
Department of Hygiene, Sapporo Medical University School of Medicine, Sapporo, Hokkaido, Japan.
Ann Ib Postgrad Med
June 2023
Department of Pharmaceutical Microbiology, Faculty of Pharmacy, University of Ibadan, Ibadan Nigeria.
Background: Skin sepsis is a pyodermal infection caused by Lancefield's group streptococci and . It is characterized by discolored and mottled skin, cellulitis, impetigo and multi-systemic collagen muscularitis and can be transmitted from person to person.
Objective: This study sampled the skin of consented abattoir workers in Moniya Ibadan, for clinical sepsis, with a view to establishing a causal relationship between the infection obtained and the abattoir workers examined.
Lancet Reg Health West Pac
June 2023
University of Western Australia, 35 Stirling Highway, Perth, Western Australia 6009, Australia.
Background: While there are many skin infections, reducing the burden of scabies and impetigo for remote living Aboriginal people, particularly children remains challenging. Aboriginal children living in remote communities have experienced the highest reported rate of impetigo in the world and are 15 times more likely to be admitted to hospital with a skin infection compared to non-Aboriginal children. Untreated impetigo can develop into serious disease and may contribute to the development of acute rheumatic fever (ARF) and rheumatic heart disease (RHD).
View Article and Find Full Text PDFJ Antimicrob Chemother
August 2023
Department of Microbiology, LHUB-ULB, National Reference Centre for Staphylococcus aureus and other species, Université libre de Bruxelles, route de Lennik 808, 1070 Brussels, Belgium.
Objectives: In August 2018, a public health alert was issued in Belgium regarding clusters of impetigo cases caused by the epidemic European fusidic acid-resistant impetigo clone (EEFIC) of Staphylococcus aureus. As a result, the Belgian national reference centre (NRC) was commissioned to update the epidemiology of S. aureus causing community-onset skin and soft tissues infection (CO-SSTI) to assess the proportion of EEFIC among them.
View Article and Find Full Text PDFIndian J Dermatol Venereol Leprol
January 2024
Department of Dermatology, Armed Forces Medical College (AFMC), Wanowarie, Pune, India.
Pustular psoriasis is a distinct subset of psoriasis that presents with involvement of the skin in the form of sterile pustules along with systemic manifestations. Though it has been conventionally grouped under the umbrella of psoriasis, recent research has shed light on its pathogenetic mechanisms associated with the IL-36 pathway, which is distinct from conventional psoriasis. Pustular psoriasis in itself is a heterogeneous entity consisting of various subtypes, including generalised, localised, acute, and chronic forms.
View Article and Find Full Text PDFThe World Health Organization published the preferred product characteristics for a Group A Streptococcus (Strep A) vaccine in 2018. Based on these parameters for the age of vaccination, vaccine efficacy, duration of protection from vaccine-derived immunity, and vaccination coverage, we developed a static cohort model to estimate the projected health impact of Strep A vaccination at the global, regional, and national levels and by country-income category. We used the model to analyse six strategic scenarios.
View Article and Find Full Text PDFJ Clin Med
June 2023
Department of Dermatology, Eastern Health, Monash University, Melbourne, VIC 3128, Australia.
Front Cardiovasc Med
May 2023
Department of Respiratory Medicine, Shenzhen Children's Hospital, Shenzhen, China.
Introduction: The incidences of acute rheumatic fever (ARF) and rheumatic heart disease (RHD), which were leading causes of death in children in the 1920s, have decreased substantially. Considering the recent resurgence of scarlet fever and increased incidence of streptococcal pharyngitis in children, an investigation of the current status of ARF and RHD may be worthwhile.
Objective: To summarize the prevalence trends, pathogenic factors, and prevention strategies for ARF and RHD in children.
Methods Mol Biol
June 2023
Department of Molecular Medicine & Pathology, School of Medical Sciences and Maurice Wilkins Centre for Biomolecular Discovery, The University of Auckland, Auckland, New Zealand.
Group A Streptococcus (GAS, Streptococcus pyogenes) is an exclusively human pathogen that causes a range of diseases, including pharyngitis, tonsillitis, impetigo, erysipelas, necrotizing fasciitis, and toxic shock syndrome. Post-streptococcal sequelae include acute rheumatic fever and rheumatic heart disease. The bacterium produces a large arsenal of virulence factors that contribute to host tissue adhesion/colonization, bacterial spread, and host immune evasion.
View Article and Find Full Text PDFAm J Case Rep
May 2023
Department of Internal Medicine, Corewell Health William Beaumont University Hospital, Royal Oak, MI, USA.
BACKGROUND Leukocytoclastic vasculitis is a small-vessel vasculitis associated with infections, autoimmune disorders, and certain drugs, but it may also be idiopathic. CASE REPORT We report the case of a 37-year-old woman with no significant past medical history who presented with a chief concern of a full-body rash. Before the rash appeared, she had been treated for group A Streptococcus with amoxicillin and prednisone.
View Article and Find Full Text PDFLancet Microbe
July 2023
Department of Infectious Diseases, University of Melbourne, Melbourne, VIC Australia; Victorian Infectious Diseases Service, The Royal Melbourne Hospital, Melbourne, at the Peter Doherty Institute for Infection and Immunity VIC, Australia; Global and Tropical Healthy Division, Menzies School of Health Research, Charles Darwin University, Darwin, NT, Australia. Electronic address:
Lancet Glob Health
June 2023
The Kirby Institute, University of New South Wales, Sydney, NSW, Australia.
Background: Integrated programmes that use combination mass drug administration (MDA) might improve control of multiple neglected tropical diseases simultaneously. We investigated the impact of Timor-Leste's national ivermectin, diethylcarbamazine citrate, and albendazole MDA, for lymphatic filariasis elimination and soil-transmitted helminth (STH) control, on scabies, impetigo, and STH infections.
Methods: We did a before-after study in six primary schools across three municipalities in Timor-Leste (urban [Dili], semi-urban [Ermera], and rural [Manufahi]) before (April 23 to May 11, 2019) and 18 months after (Nov 9 to Nov 27, 2020) MDA delivery between May 17 and June 1, 2019.
Mil Med
May 2023
Department of Dermatology, San Antonio Military Medical Center, Fort Sam Houston, TX 78234, USA.
The differential diagnosis of vesiculobullous lesions can be intimidating to the primary care provider. While some entities such as bullous impetigo may easily be diagnosed clinically if the patient's demographics as well as the lesion morphology and distribution present classically, atypical presentations may require additional laboratory studies for confirmation. We describe a case of bullous impetigo with characteristics that clinically mimicked two rare immunobullous dermatoses.
View Article and Find Full Text PDFNPJ Vaccines
May 2023
International Vaccine Institute, Seoul, South Korea.
Considering the lack of existing evidence on economic burden for diseases caused by group A Streptococcus, we estimated the economic burden per episode for selected diseases. Each cost component of direct medical costs (DMCs), direct non-medical costs (DNMCs), and indirect costs (ICs) was separately extrapolated and aggregated to estimate the economic burden per episode by income group as classified by the World Bank. Adjustment factors for DMC and DNMC were generated to overcome related data insufficiencies.
View Article and Find Full Text PDFJ Allergy Clin Immunol Pract
August 2023
Department of Dermatology, Medicine and Pathology, University of Rochester Medical Center, Rochester, NY. Electronic address:
Obstet Med
March 2023
Faculty of Medicine, Ain Shams University, Cairo, Egypt.
Impetigo herpetiformis (IH) is a pregnancy-specific dermatosis that is currently considered a form of generalised pustular psoriasis and mainly occurs in late pregnancy during the third trimester. IH presents as erythematous patches and pustules and might have systemic involvement. The disease may be associated with severe maternal, fetal, and neonatal complications.
View Article and Find Full Text PDFIsr Med Assoc J
April 2023
Department of Pediatrics, Adams Children's Hospital, Wolfson Medical Center, Holon, Israel, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Background: The global refugee crises have raised concerns among medical communities worldwide; nonetheless, access to healthcare has rarely been studied even though refugees are a medically high-risk group.
Objectives: To compare pediatric department admission rates from the pediatric emergency department (PED) of refugees and Israelis.
Methods: We compared data from refugee and Israeli children admitted to the pediatric department at Wolfson Medical Center in Israel between 2013-2017.