2,340 results match your criteria: "Impetigo"
[About impetigo: a brief historical overview].
Medicina (B Aires)
August 2024
Hospital de Simulación y Laboratorios, Facultad de Ciencias de la Salud y Programa de Magíster en Salud Pública, Facultad de Ciencias Médicas, Universidad Bernardo O'Higgins, Santiago, Chile. E-mail:
Chemical optimization and derivatization of micrococcin p2 to target multiple bacterial infections: new antibiotics from thiopeptides.
World J Microbiol Biotechnol
August 2024
A&J Science Co., Ltd, 80 Chumbok Ro, Dong Gu, Daegu, 41061, Republic of Korea.
Article Synopsis
- * Research emphasizes efficient synthetic methods for producing MP2, which allows for better understanding and enhancement of its properties, leading to the identification of effective lead compounds AJ-037 and AJ-206 for treating Mycobacterium avium complex infections.
- * Two other candidates, AJ-024 and AJ-147, exhibit strong efficacy against Clostridioides difficile and methicillin-resistant Staphylococcus aureus, respectively, with AJ-147 also showing potential anti-inflammatory benefits, positioning
Invasive Streptococcus pyogenes infection: a case report.
Access Microbiol
July 2024
Department of Clinical Bacteriology, Mohammed V Military Teaching Hospital, Faculty of Medicine and Pharmacy, Mohammed V University, Rabat, Morocco.
Article Synopsis
- - Group A Streptococcus (GAS) is a bacteria that can cause a range of infections, from mild issues like tonsillitis to severe ones like septicemia, and has seen a resurgence in severe cases since the 1980s.
- - A case study describes a 28-year-old man in Morocco who developed septic arthritis after experiencing flu-like symptoms and tonsillitis, leading to significant swelling and joint pain.
- - Treatment involved dual antibiotics and drainage of an abscessed knee joint, highlighting the importance of prompt detection and treatment of severe GAS infections, along with advocating for antibiotic prophylaxis recommendations.
Characterization of group A streptococci causing invasive diseases in Sri Lanka.
Access Microbiol
June 2024
Department of Microbiology, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, SAR.
Article Synopsis
- Group A β haemolytic streptococcus (GAS) is a pathogen that causes various infections in humans, and this study analyzed 51 GAS isolates from invasive infections in Sri Lanka.
- The isolates were tested for resistance to antibiotics like erythromycin and tetracycline, revealing that all were susceptible to penicillin and showing diverse patterns of resistance and virulence markers.
- Key findings included a 70.6% non-susceptibility rate to tetracycline and the detection of significant virulence markers, indicating a varied genetic background among the isolates.
Two-sample Mendelian randomization analysis identifies a causal association between atopic dermatitis and impetigo.
Int J Dermatol
September 2024
Department of Dermatology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Article Synopsis
- In Australia, pharmacists' prescribing abilities have recently expanded to include more medications, specifically for urinary tract infections, certain dermatological conditions, and contraceptives, in a trial initiated by the NSW Government.
- This sub-study aims to gather insights from Aboriginal and Torres Strait Islander communities and healthcare practitioners about their perspectives on this expanded prescribing practice, including potential risks and benefits.
- Methods include yarning circles and semi-structured interviews with local leaders, clinicians, and community members, seeking to understand the community's unique views and concerns regarding the changes in pharmacist roles.
Common Skin Conditions in Children and Adolescents: Bacterial Infections.
FP Essent
June 2024
Department of Family and Community Medicine, University of Texas Health, San Antonio.
Article Synopsis
- * Impetigo is frequently seen in children and can be treated with topical antibiotics; however, oral antibiotics may be warranted in cases of outbreaks or multiple lesions.
- * For abscess-related issues like furuncles and carbuncles, management typically involves incision and drainage, with oral antibiotics reserved for severe cases or immunocompromised patients; methicillin-resistant coverage may be needed if treatments fail.
Depressive Disorder and Dermatological Autoimmune Diseases.
J Clin Med
May 2024
Department of Adult Psychiatry, Medical University of Lodz, 92-213 Lodz, Poland.
Article Synopsis
- - Depressive disorders are increasing globally and often occur alongside various dermatological conditions, particularly autoimmune diseases.
- - A review of studies published since 2016 identified strong links between depression and specific skin diseases like psoriasis, atopic dermatitis, and lupus.
- - The inflammation theory suggests that shared inflammatory processes might underlie both depression and autoimmune diseases, explaining their co-occurrence.
Eczema herpeticum in an immunocompetent man.
Diagn Microbiol Infect Dis
September 2024
Division of Nephrology, Department of Internal Medicine, Tungs' Taichung Metro Harbor Hospital, Taichung City, Taiwan, R.O.C. Electronic address:
Article Synopsis
- Eczema herpeticum is a serious skin condition caused by the herpes simplex virus, commonly affecting those with weakened immune systems or skin conditions like atopic dermatitis, leading to painful lesions and potential severe complications without proper treatment.
- A case study highlighted a young patient with ankylosing spondylitis, who improved after receiving antiviral and antibiotic treatment, despite not being on immunosuppressive therapy or having a history of related conditions.
- The rise in eczema herpeticum cases is linked to more people with compromised immune systems due to factors like increased HIV/AIDS prevalence, more immunosuppressive treatments, and a rise in atopic dermatitis cases, which can complicate diagnosis due to overlapping symptoms with other conditions like Stevens-John
Generalized Pustular Psoriasis of Pregnancy Successfully Treated With Certolizumab Pegol: A Case Report and Literature Review.
Cureus
May 2024
Center for Dermatology, Allergology and Dermatosurgery, Helios University Hospital Wuppertal, Wuppertal, DEU.
Article Synopsis
- * A case study highlights the effective use of certolizumab pegol, a tumor necrosis factor-alpha inhibitor (TNFi), to manage severe GPPP in a 28-year-old woman.
- * The report includes a review of existing literature on TNFi treatments for GPPP, featuring only 11 documented cases, and discusses the underlying mechanisms of GPPP and why TNFi might be a suitable treatment choice.
Managing outbreak of community-onset paediatric impetigo in underserved areas of North India via teledermatology: A tertiary care centre's experience.
Indian J Dermatol Venereol Leprol
May 2024
Department of Telemedicine, Postgraduate Institute of Medical Sciences and Research (PGIMER), Chandigarh, India.
Comparison of selected cytomorphological features of canine pemphigus foliaceus and superficial pyoderma.
Vet Dermatol
October 2024
College of Veterinary Medicine, North Carolina State University, Raleigh, North Carolina, USA.
Background: Cytological detection of acantholytic keratinocytes (acantholytic cells [AC]) helps to identify canine pemphigus foliaceus (cPF) yet AC also occurs in superficial pyoderma (SP), the main differential diagnosis.
Hypothesis/objectives: To compare selected cytomorphological features of cPF and SP and to establish cytological diagnostic criteria that could differentiate cPF from SP.
Animals: 40 and 51 client-owned dogs with PF and SP, respectively.
Prevalence and associated risk factors of scabies and impetigo: A cross-sectional study in Tutume district, Botswana.
PLoS Negl Trop Dis
June 2024
Department of Family Medicine & Public Health, Faculty of Medicine, University of Botswana, Gaborone, Botswana.
Article Synopsis
- The study evaluates the prevalence and risk factors of scabies and impetigo in the Nata and Sowa areas of the Tutume district, noting a significant lack of previous epidemiological data, especially in sub-Saharan Africa.
- A cross-sectional study revealed an overall scabies prevalence of 18.18%, with the highest rates in the communities of Manxhotae and Ndutshaa, while impetigo cases were rare.
- Key risk factors identified include younger age groups (0-4 years and 5-18 years) and having a household member with itching, indicating a need for more research on household transmission dynamics.
Dermatologic Care for Refugees: Effective Management of Scabies and Pediculosis.
Cutis
April 2024
Alexis G. Strahan is from the Mercer University School of Medicine, Savannah, Georgia. Dr. Elston is from the Department of Dermatology and Dermatologic Surgery, Medical University of South Carolina, Charleston.
There is a large burden of treatable dermatologic conditions in refugee populations. Parasitic infestations are particularly common when there are barriers to basic hygiene, crowded living or travel conditions, and lack of access to health care. Body lice are associated with anemia and can transmit a variety of diseases; chronic impetigo secondary to scabies is a leading cause of chronic kidney disease globally.
View Article and Find Full Text PDFUse of biologics in Chinese pregnant patients with deficiency of interleukin-36 receptor antagonist (DITRA): A case series.
Taiwan J Obstet Gynecol
May 2024
Department of Dermatology, National Taiwan University Hospital, Taipei, Taiwan. Electronic address:
Article Synopsis
- Impetigo herpetiformis (IH) is a rare and severe skin condition linked to pregnancy complications, primarily caused by a genetic defect in the IL36RN gene.
- This case series of six Chinese patients with IH during eight pregnancies explored the use of various biologics, like adalimumab, etanercept, and secukinumab, to manage their condition.
- Most patients had successful pregnancies, but one experienced fetal heart rate issues that improved after changing medications, indicating that biologics may be beneficial for treating IH in those with the genetic defect.
Draft genome sequence data of methicillin-resistant , strain 4233.
Data Brief
June 2024
Research and Production Center for Microbiology and Virology, Bogenbay batyr. Str., 105, Almaty 050010, Kazakhstan.
Article Synopsis
Papulovesicular Riddle in an Atopic Individual.
Cureus
April 2024
Internal Medicine, Saint Peter's University Hospital, New Brunswick, USA.
Article Synopsis
- Atopic dermatitis (AD) leads to skin irritation and can increase the risk of infections, especially in those affected by the condition.
- Eczema herpeticum (EH) is a serious herpes simplex infection that appears as vesicles and erosions in areas already affected by AD, and misdiagnosing it can have severe consequences.
- Prompt identification and treatment with acyclovir are essential to prevent serious complications, as illustrated by a case involving a 19-year-old male with AD presenting a similar rash.
Emergence and spread of a mupirocin-resistant variant of the European epidemic fusidic acid-resistant impetigo clone of , Belgium, 2013 to 2023.
Euro Surveill
May 2024
National reference centre for Staphylococcus aureus and other species, Department of microbiology, Laboratoire Hospitalier Universitaire de Bruxelles - Universitair Laboratorium Brussel (LHUB-ULB), Université libre de Bruxelles, Brussels, Belgium.
Article Synopsis
- Resistance to mupirocin and fusidic acid in community-acquired MSSA skin infections in Belgium is on the rise, emphasizing a significant public health concern.
- Data collected from 2013 to 2023 showed mupirocin resistance increased from 0.5-1.5% to 1.7-5.6%, with a notable 91.4% of resistant strains also resistant to fusidic acid.
- A specific mupirocin-resistant strain (sequence type 121) has become prevalent among children, carrying resistance genes and virulence factors, indicating a worrying trend for the effectiveness of current treatments for impetigo.
Tonsils at Telethon: developing a standardised collection of tonsil photographs for group A streptococcal (GAS) research.
Front Pediatr
April 2024
Wesfarmers Centre of Vaccines and Infectious Diseases, Telethon Kids Institute, University of Western Australia, Perth, WA, Australia.
Introduction: Group A streptococcus (GAS) infections, such as pharyngitis and impetigo, can lead to rheumatic fever and rheumatic heart disease (RHD). Australian Aboriginal and Torres Strait Islander populations experience high rates of RHD and GAS skin infection, yet rates of GAS pharyngitis are unclear. Anecdotally, clinical presentations of pharyngitis, including tonsillar hypertrophy and sore throat, are uncommon.
View Article and Find Full Text PDFEliminate all risks: A call to reexamine the link between canine scabies and rheumatic heart disease.
PLoS Negl Trop Dis
May 2024
Australian Centre for Health Engagement, Evidence and Values, Faculty of the Arts, Social Sciences and the Humanities, University of Wollongong, Keiraville, New South Wales, Australia.
Rheumatic heart disease (RHD) and acute rheumatic fever (ARF) disproportionately affect individuals in low-resource settings. ARF is attributed to an immune response to Group A Streptococcus (GAS) following GAS pharyngitis and potentially GAS impetigo in which infection can be initiated by scabies infestation. The burden of ARF and RHD in Aboriginal and Torres Strait Islander people in Australia is among the highest globally.
View Article and Find Full Text PDFQbD Based Formulation Development and Optimisation of Ozenoxacin Topical Nano-Emulgel and Efficacy Evaluation Using Impetigo Mice Model.
AAPS PharmSciTech
April 2024
Chemical Engineering, JNTUA College of Engineering (Autonomous), Jawaharlal Nehru Technological University Anantapur (JNTUA), Ananthapuramu, Andhra Pradesh, 515002, India.
To formulate and optimize Ozenoxacin nano-emulsion using Quality by Design (QbD) concept by means of Box-Behnken Design (BBD) and converting it to a gel to form Ozenoxacin nano-emulgel followed by physico-chemical, in-vitro, ex-vivo and in-vivo evaluation. This study demonstrates the application of QbD methodology for the development and optimization of an effective topical nanoemulgel formulation for the treatment of Impetigo focusing on the selection of appropriate excipients, optimization of formulation and process variables, and characterization of critical quality attributes. BBD was used to study the effect of "% of oil, % of S and homogenization speed" on critical quality attributes "globule size and % entrapment efficiency" for the optimisation of Ozenoxacin Nano-emulsion.
View Article and Find Full Text PDFRecombinational exchange of M-fibril and T-pilus genes generates extensive cell surface diversity in the global group A population.
mBio
May 2024
Eagle Global Scientific, LLC, Atlanta, Georgia, USA.
Among genes present in all group A streptococci (GAS), those encoding M-fibril and T-pilus proteins display the highest levels of sequence diversity, giving rise to the two primary serological typing schemes historically used to define strain. A new genotyping scheme for the pilin adhesin and backbone genes is developed and, when combined with typing, provides an account of the global GAS strain population. Cluster analysis based on nucleotide sequence similarity assigns most T-serotypes to discrete pilin backbone sequence clusters, yet the established T-types correspond to only half the clusters.
View Article and Find Full Text PDFRecent Scientific Advancements towards a Vaccine against Group A .
Vaccines (Basel)
March 2024
School of Chemistry and Molecular Biosciences, The University of Queensland, St. Lucia, QLD 4072, Australia.
Article Synopsis
- Group A Streptococcus (GAS) is a gram-positive bacterium that can cause various infections like pharyngitis and necrotizing fasciitis, and can lead to serious autoimmune diseases, especially in children and the elderly.
- Antibiotic treatment is essential for managing GAS infections, but rising antibiotic resistance poses a significant challenge to effective treatment.
- Despite over a century of efforts, no GAS vaccines have been approved, though recent research into GAS's pathogenic mechanisms offers new insights for future vaccine development.
Prevalence and determinants of impetigo in Ghana: a cross-sectional study.
BMC Infect Dis
March 2024
Department of Internal Medicine/Infectious Diseases, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Article Synopsis
- Skin diseases like impetigo and scabies are prevalent in Ghana, with a significant portion of the population affected, yet there's limited data on their prevalence.
- A cross-sectional study involving 1,327 participants from various settings in Ghana found that 14% had impetigo, often mild, and 56.2% had scabies, with a notable overlap between the two conditions.
- Key factors increasing the risk of impetigo included having an itch, presence of scabies, and being in preschool, highlighting the need for improved detection and control measures as part of health initiatives in the region.