2,340 results match your criteria: "Impetigo"
Bullous impetigo due to methicillin-resistant Staphylococcusaureus.
Semergen
December 2024
Department of Dermatology, Hospital Universitario y Politécnico La Fe, Valencia, Spain; Instituto de Investigación Sanitaria (IIS) La Fe, Valencia, Spain.
Default Antibiotic Order Durations for Skin and Soft Tissue Infections in Outpatient Pediatrics: A Cluster Randomized Trial.
J Pediatric Infect Dis Soc
December 2024
Division of Pediatric Infectious Diseases, Department of Pediatrics, Center for Clinical Excellence, Nationwide Children's Hospital and The Ohio State University College of Medicine, Columbus, OH, USA.
Background: Antibiotic durations for uncomplicated skin/soft tissue infections (SSTI) often exceed the guideline-recommended 5-7 days. We assessed the effectiveness of a default duration order panel in the Electronic Health Record (EHR) to reduce long prescriptions.
Methods: Cluster randomized trial of a SSTI order panel with default antibiotic durations (implemented 12/2021), compared to a control panel (no decision support) in 14 pediatric primary care clinics.
Multi-methods process evaluation of the SToP (See, Treat, Prevent) trial: a cluster randomised, stepped wedge trial to support healthy skin.
EClinicalMedicine
November 2024
Wesfarmers Centre of Vaccines and Infectious Diseases, Telethon Kids Institute, University of Western Australia, Nedlands, WA, Australia.
Background: Healthy skin is important for maintaining overall physical and cultural health and wellbeing. However, remote-living Australian Aboriginal children contend with disproportionally high rates of (Strep A) infected impetigo. The SToP Trial was a large stepped-wedge cluster randomised trial of See, Treat, and Prevent (SToP) skin health activities implemented between 2019 and 2022 in the Kimberley region of Western Australia, during which a decrease in impetigo was observed.
View Article and Find Full Text PDFBurden of scabies in a Ghanaian penitentiary.
PLoS One
December 2024
Department of Internal Medicine/Infectious Diseases, University Medical Center, Groningen, University of Groningen, Groningen, Netherlands.
Background: There is a dearth of information concerning the epidemiology of human scabies in prisons. Therefore, we aimed to assess the burden of scabies and ascertain if prevalence was high enough to warrant mass drug administration (MDA) with ivermectin in a medium security prison in central Ghana.
Methods: We conducted a cross-sectional study in December 2022 and recruited inmates at the Kumasi central prison in Ghana.
THE CLINICAL MANIFESTATIONS OF SCABIES IN PATIENTS PRESENTING TO DERMATOLOGY OUTPATIENTS DEPARTMENT AT AYUB TEACHING HOSPITAL, ABBOTTABAD.
J Ayub Med Coll Abbottabad
November 2024
Department of Dermatology, Ayub Medical College, Abbottabad-Pakistan.
Article Synopsis
[Genetic diseases with skin fragility in children].
Dermatologie (Heidelb)
December 2024
Klinik für Dermatologie und Venerologie, Universitätsklinikum Freiburg, Hauptstr. 7, 79104, Freiburg, Deutschland.
Article Synopsis
- Genetic diseases that cause skin fragility are diverse in their symptoms and genetic causes, making it crucial for healthcare professionals to differentiate them from more common conditions like infections or burns.
- The classification of these rare diseases is guided by their clinical presentation, histological characteristics, and genetic mutations, with most treatments being symptomatic rather than curative.
- Advances in genetic testing have integrated the study of these rare diseases into everyday clinical practice, emphasizing the need for collaboration among specialists to ensure proper diagnosis and care for affected children.
Prevalence and Socio-Demographic and Hygiene Factors Influencing Impetigo in Saudi Arabian Children: A Cross-Sectional Investigation.
Clin Cosmet Investig Dermatol
November 2024
Department of Medical-surgical Nursing, Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia.
Article Synopsis
- * A total of 1200 children participated, mostly girls, and findings indicated a significant link between poor personal hygiene and higher rates of impetigo among the children.
- * Socio-demographic elements like gender, parental education, job status, and location were found to significantly influence impetigo cases, highlighting the importance of good hygiene practices in preventing the infection.
Cutaneous Changes During Pregnancy: A Comprehensive Review.
Cureus
September 2024
Dermatology, Venereology and Leprosy, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education & Research, Wardha, IND.
Article Synopsis
- Pregnancy leads to significant changes in a woman’s skin, particularly on the face and trunk, due to hormonal, mechanical, and immune factors.
- Common skin alterations during this time include hyperpigmentation, stretch marks, and various vascular changes, along with potential issues like skin tags and other specific conditions.
- Understanding these changes is crucial for healthcare providers to offer proper support and management for expectant mothers, improving clinical care and paving the way for future research.
Ivermectin-Based Mass Drug Administration for Scabies in Northern India: A Single-Arm Community Intervention Trial.
Open Forum Infect Dis
October 2024
Nossal Institute for Global Health, School of Population and Global Health, University of Melbourne, Melbourne, Victoria, Australia.
Background: Scabies and impetigo cause direct health effects and contribute to severe infectious and immune-mediated complications. Ivermectin-based mass drug administration can reduce scabies and impetigo prevalence in island settings with high prevalence, but the effectiveness in moderate-prevalence settings is not known.
Methods: We conducted a single-arm, before-after community intervention trial.
Systematic review of the evidence for treatment and management of common skin conditions in resource-limited settings: An update.
Trop Med Int Health
November 2024
Wesfarmers Centre of Vaccines and Infectious Diseases, Telethon Kids Institute, Nedlands, Western Australia, Australia.
Article Synopsis
- The skin is the largest organ and skin infections can seriously affect health and self-image, which prompted a systematic review that updates treatment strategies for various skin infections prevalent in resource-limited settings.
- This review builds on a previous one from 2019 and incorporates new data on conditions like atopic dermatitis and head lice to revise the Australian National Healthy Skin guidelines.
- A thorough search of medical literature from 1960 to 2022 identified 68 studies focusing on the treatment of specific skin infections among Indigenous populations in lower-income areas, leading to key recommendations based on the evidence gathered.
Trimodal skin health programme for childhood impetigo control in remote Western Australia (SToP): a cluster randomised, stepped-wedge trial.
Lancet Child Adolesc Health
November 2024
Wesfarmers Centre of Vaccines and Infectious Diseases, The Kids Research Institute of Australia (formerly Telethon Kids Institute), University of Western Australia, Nedlands, WA, Australia; Department of Infectious Diseases, Perth Children's Hospital, Nedlands, WA, Australia. Electronic address:
Article Synopsis
- A study was conducted to evaluate the impact of a holistic skin control program, SToP, aimed at reducing impetigo among children in remote communities of the Kimberley, Western Australia.
- The trial involved skin checks, treatment training, and health promotion, targeting children aged 0-18 years in a stepped-wedge randomization process.
- Results showed a significant decline in impetigo cases, particularly noted during initial baseline skin checks prior to the official intervention, with 85% of consented children receiving at least one skin assessment.
Review - Expert Opinion on Antibiotics and Antibiotic Resistance in Dermatology.
Dermatol Pract Concept
October 2024
Corso di Clinica Dermatologica, Università di Milano Bicocca e Ospedale San Raffaele, Milano.
Article Synopsis
- Antibiotic resistance is a growing global issue, affecting both systemic and topical treatments for infections, highlighting the need for alternatives like antiseptics.
- Polyhexanide (PHMB) is noted for its effectiveness in controlling infections without promoting resistance, making it a viable option for treating various dermatological conditions.
- The text suggests updated clinical practices for managing wounds and skin infections, advocating for the use of innovative treatments like PHMB and Rigenase® instead of traditional topical antibiotics.
Costs of primary healthcare presentations and hospital admissions for scabies and related skin infections in Fiji, 2018-2019.
PLOS Glob Public Health
October 2024
School of Population and Global Health, University of Melbourne, Melbourne, Australia.
Article Synopsis
- Scabies and related bacterial skin infections are common in tropical and low-income areas, significantly raising healthcare costs and straining health systems.
- The "Big SHIFT" trial in Fiji analyzed scabies and SSTIs from 2018 to 2019, aiming to estimate the healthcare costs associated with these conditions before a mass drug treatment campaign.
- The study found that healthcare costs for scabies and SSTIs in Fiji totaled approximately $3 million annually, with an estimated cost of $3.3 per person, highlighting the economic impact and the potential benefits of prevention efforts.
Rapid identification of primary atopic disorders (PAD) by a clinical landmark-guided, upfront use of genomic sequencing.
Allergol Select
October 2024
Center for Child and Adolescent Health, Helios Hospital Krefeld, Academic Hospital of RWTH Aachen, Krefeld.
Article Synopsis
- Primary atopic disorders (PAD) are rare genetic conditions caused by specific gene variants that affect skin and immune function, making diagnosis challenging among common allergic disease cases.
- Identifying PAD requires recognizing clinical red flags like family history and unusual infections, as conventional lab tests are inadequate for definitive diagnosis.
- Whole-genome sequencing (WGS) enhances diagnostic efficiency and accuracy, but requires careful interpretation and collaboration among specialists to effectively manage PAD cases.
Itchy and Swollen: Atopic Dermatitis With Cephalocervical Lymphadenitis in an Infant.
Cureus
September 2024
Pediatrics, El Paso Kids Klinic, El Paso, USA.
Article Synopsis
- A three-month-old Hispanic baby girl was seen by doctors for a skin condition called atopic dermatitis and a rare issue with her lymph nodes.
- She had been dealing with redness, irritation, and itching on her scalp, face, and body for three months.
- It's important for doctors to know about this rare combination of problems to help diagnose and treat patients better in the future.
Article Synopsis
- * A panel of pediatric dermatologists developed five consensus statements addressing the management of S. aureus-related AD exacerbations and current treatment challenges, emphasizing the need for improved patient care.
- * The panel highlighted the need for a comprehensive topical therapy that targets multiple symptoms of AD, including itch, infections, and inflammation, while also advocating for prudent antibiotic use to prevent resistance.
Inhibition of biofilm by and .
mSphere
October 2024
Department of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, University Zurich, Zurich, Switzerland.
Article Synopsis
- The study investigates the anti-biofilm effects of cell-free supernatants from two probiotic bacterial strains on a human pathobiont responsible for serious infections, including pharyngotonsillitis and necrotizing fasciitis.
- It finds that these supernatants significantly reduce the survival of both planktonic and biofilm forms of the pathogen, particularly affecting already established biofilms more intensely, suggesting the involvement of glycolipid compounds in this antimicrobial action.
- The results highlight the need for new therapeutic strategies against biofilm-associated infections, particularly for vulnerable populations, and aim to enhance understanding of lactobacillus properties that could lead to innovative treatment options.
Housing Initiatives to Address Strep A Infections and Reduce RHD Risks in Remote Indigenous Communities in Australia.
Int J Environ Res Public Health
September 2024
School of Public Health, Faculty of Medicine, The University of Queensland, Brisbane, QLD 4072, Australia.
Article Synopsis
- - Group A Streptococcus (Strep A) skin infections, like impetigo, can lead to serious conditions such as acute rheumatic fever (ARF) and rheumatic heart disease (RHD), particularly in Indigenous communities where these rates are significantly higher.
- - Strep A can spread through three key ways: direct skin contact, surface contamination, and airborne transmission, highlighting the importance of addressing these pathways.
- - The study suggests various household-level initiatives to reduce Strep A transmission, such as improving washing facilities, enhancing yard space for better social distancing, and increasing home ventilation, with an interactive tool developed to evaluate these initiatives' costs and effectiveness.
Exploring the Potential of DALL-E 2 in Pediatric Dermatology: A Critical Analysis.
Cureus
August 2024
Dermatology, Tufts Medical Center, Boston, USA.
Article Synopsis
- DALL-E 2, an AI model known for generating realistic images from text, was evaluated for its use in dermatology by creating images of 12 common pediatric skin conditions.
- Out of 24 images produced, 18 were photorealistic, but the AI struggled with most diagnoses, only accurately depicting acne.
- The study concluded that DALL-E 2 requires better training with diverse and specific data to enhance its effectiveness in dermatological applications.
Efficacy of Extract against 7,12-Dimethylbenz[]anthracene-Induced Cancer in Mice.
J Microbiol Biotechnol
November 2024
Department of Pharmacology, Hanoi Medical University, Hanoi, Vietnam.
Article Synopsis
- Blume tea, a traditional Vietnamese medicine, has shown potential in treating various health issues and possesses diverse pharmacological properties, although its anticancer effects were previously unclear.
- Recent studies indicated that extracts from J. subtriplinerve, specifically the ethyl acetate fraction, demonstrated significant anti-proliferative effects on breast cancer cells while other fractions did not show efficacy.
- In mouse models, the ethyl acetate fraction reduced tumor incidence and mortality when administered, suggesting that Blume tea could be a safe and effective chemopreventive option against breast cancer.
Local anaesthetic to reduce injection pain in patients who are prescribed intramuscular benzathine penicillin G: a systematic review and meta-analysis.
EClinicalMedicine
October 2024
Institute of Health Informatics Research, University College London, London, UK.
Article Synopsis
- Prolonged intramuscular injections of benzathine penicillin G (BPG) are essential for preventing group A streptococcal infections and reducing the risk of rheumatic fever and heart disease, but the pain from these injections may reduce patient compliance.
- * This systematic review and meta-analysis aimed to evaluate the effectiveness of local anaesthetics in reducing pain associated with BPG injections by analyzing randomised controlled trials comparing BPG alone to BPG with anaesthetics.
- * Out of 3958 records, eight trials with 489 patients were included, revealing that while patients reported high levels of immediate pain, some still experienced low-intensity pain 24 hours later.
Eczema Herpeticum: Clinical Insights and Pathogenesis Hypotheses on Basolateral Adhesion Proteins.
Cureus
August 2024
Internal Medicine, XXI Century National Medical Center, Ciudad de México, MEX.
Article Synopsis
- Eczema herpeticum (EH) is a serious viral infection caused by the herpes simplex virus that affects individuals with fragile skin, particularly those with atopic dermatitis (AD), leading to severe skin lesions and possible systemic issues.
- A case report describes an EH diagnosis in a five-year-old girl with AD, characterized by fever and painful skin lesions, ultimately confirmed through positive IgM anti-HSV-1 serology despite initial lack of confirmatory tests.
- The girl was treated with intravenous aciclovir and showed significant improvement in just 48 hours, emphasizing the need for quick diagnosis and treatment, as well as further research on the link between structural protein changes and immune dysfunction in EH.
Unveiling the multitargeted potential of deprodone and control comparison with linezolid against hydrolase and transferase enzymes of methicillin-resistant Staphylococcus aureus.
Int J Biol Macromol
November 2024
Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, Shaqra University, Al-Quwayiyah 19257, Riyadh, Saudi Arabia. Electronic address:
Article Synopsis
- Staphylococcus aureus (S. aureus) is a bacteria that can cause various infections, with MRSA being a resistant strain that complicates treatment options and necessitates the search for alternative drugs like Linezolid.
- A study focused on finding a more effective multitargeted drug candidate than Linezolid by examining certain proteins in S. aureus and performing docking studies, leading to promising results for the drug Deprodone.
- Further investigations into the stability and interactions of Deprodone with the target proteins showed favorable outcomes, but experimental validation against MRSA is still required to confirm its efficacy as a therapeutic option.