Neurodegenerative disease and obesity: what is the role of weight loss and bariatric interventions?

Neurodegenerative diseases are amongst the leading causes of worldwide disability, morbidity and decreased quality of life. They are increasingly associated with the concomitant worldwide epidemic of obesity. Although the prevalence of both AD and PD continue to rise, the available treatment strategies to combat these conditions remain ineffective against an increase in global neurodegenerative risk factors.

Familial epilepsy in the pharaohs of ancient Egypt's eighteenth dynasty.

The pharaohs of Egypt's famous eighteenth dynasty all died early of unknown causes. This paper comprehensively reviews and analyses the medical literature and current evidence available for the New Kingdom rulers - Tuthmosis IV, Amenhotep III, Akhenaten, Smenkhkare and Tutankhamun. The integration of these sources reveals that the eighteenth dynasty rulers may have suffered from an inherited condition that may explain their untimely deaths.