1 results match your criteria: "Immune Deficiencies Laboratory at the National Institute of Pediatrics[Affiliation]"
Fatal COVID-19 Infection in Two Children with STAT1 Gain-of-Function.
J Clin Immunol
December 2023
Immune Deficiencies Laboratory at the National Institute of Pediatrics, Health Secretariat, Av Iman 1, Piso 9 Torre de Investigación, Col. Insurgentes Cuicuilco, Coyoacán, 04530, Mexico City, CDMX, Mexico.
Article Synopsis
- Researchers studied two young patients with STAT1 GOF who died from severe COVID-19 complications, revealing problematic immune responses to the virus.
- Genetic testing identified two specific mutations in the STAT1 gene, which led to an overactive immune response that may have contributed to their rapid decline post-infection.