MXene-encapsulated ZIF-8@Liposomes for NIR-enhanced photothermal therapy in hepatocellular carcinoma treatment: In vitro, in vivo, and in silico study.

Photothermal therapy (PTT) utilizes near-infrared (NIR) light to enhance localized, non-invasive cancer treatments and drug delivery systems (DDS). Combination chemotherapy with PTT (chemo-PTT) offers multiple therapeutic advantages, involving synergistic effects, reduced side effects, and decreased drug toxicity. In this study, 2D titanium carbide (TiCT) MXene nanosheets were encapsulated in a zeolitic imidazolate framework-8 (ZIF-8) to form (MX-ZIF-8) nanoparticles (NPs) for PTT applications.

The process in the inverted hierarchy scenario of the 2HDM type-I at the LHC.

While searching at the Large Hadron Collider (LHC) for the production and decay of the CP-odd scalar ( ) in the 2-Higgs-Doublet Model (2HDM) with Natural Flavour Conservation (NFC) via the channels (through one-loop triangle diagrams) and (with GeV or GeV, with off-shell), respectively, a factorisation of the two processes is normally performed, with the state being on-shell. While this approach is gauge-invariant, it is not capturing the presence of either of the following two channels: (through one-loop triangle diagrams) or (through one-loop box diagrams). As the resolution of the mass cannot be infinitely precise, we affirm that all such contributions should be computed simultaneously, whichever the ( ) decay(splitting) products, thereby including all possible interferences amongst themselves.

The effects of cross-language overlap and semantic transparency on the processing of L2 collocations.

Although extensive research has been carried out on collocation processing, it is still unclear how cross-language overlap and transparency influence the processing of collocations by L2 learners. In the current study, a phrase judgment task was used to investigate the processing of congruent (i.e.

Cobalt-doped ZnO nanoparticles and PLD-deposited thin film forms: structure, optical properties and nature of magnetic anisotropy.

Cobalt-doped zinc oxide nanoparticles (NPs) were synthesized using a modified sol-gel method. Thereafter, the obtained powder was deposited on a Suprasil glass substrate by employing a pulsed laser deposition (PLD) technique. X-ray diffraction analysis with Rietveld refinement confirmed a hexagonal wurtzite ZnO phase belonging to the 6 space group for both samples in the NP and thin film forms.

The impact of genre-based instruction on Saudi university students' English writing performance and motivation: a mixed-method study.

Despite the important role motivation plays in students' writing learning and development, not much attention has been given to experimenting particular instructional techniques for developing students' writing motivation. One of the least researched teaching techniques in writing motivation studies is genre-based instruction. In this study, we examined the impact of genre-based instruction on 21 Saudi university students' English argumentative and classification essay writing performance and their writing motivation dimensions (writing apprehension, anxiety, self-efficacy and self-concept).

Preparation and characterization of various PVPylated divalent metal-doped ferrite nanoparticles for magnetic hyperthermia.

There is an incessant demand to keep improving on the heating responses of polymeric magnetic nanoparticles (MNPs) under magnetic excitation, particularly in the pursuit for them to be utilized for clinical hyperthermia applications. Herein, we report the fabrication of a panel of PVP-capped divalent metal-doped MFeO (M ≅ Co, Ni, Zn, Mg, and Sn) MNPs prepared the Ko-precipitation Hydrolytic Basic (KHB) methodology and assess their magneto-thermal abilities. The physiochemical, structural, morphological, compositional, and magnetic properties of the doped ferrites were fully characterized using various techniques mainly TEM, XRD, EDX, FTIR, and VSM.

Crucial role of interfacial interaction in 2D polar SiGe/GeC heterostructures.

The planar charge transfer is a distinctive characteristic of the two-dimensional (2D) polar materials. When such 2D polar materials are involved in vertical heterostructures (VHs), in addition to the van der Waals (vdW) interlayer interaction, the interfacial interaction triggered by the in-plane charge transfer will play a crucial role. To deeply understand such mechanism, we conducted a comprehensive theoretical study focusing on the structural stability and electronic properties of 2D polar VHs built by commensurate SiGe/GeC bilayers with four species ordering patterns (classified as a C-group with patterns I and II and a Ge-group with patterns III and IV, respectively).

Biosynthesis, characterization, magnetic hyperthermia, and in vitro toxicity evaluation of quercetin-loaded magnetoliposome lipid bilayer hybrid system on MCF-7 breast cancer.

Novel biocompatible and effective hyperthermia (HT) treatment materials for breast cancer therapeutic have recently attracting researchers, because of their effective ablation of cancer cells and negligible damage to healthy cells. Magnetoliposome (MLs) have numerous possibilities for utilize in cancer treatment, including smart drug delivery (SDD) mediated through alternating magnetic fields (AMF). In this work, magnesium ferrite (MgFeO) encapsulated with liposomes lipid bilayer (MLs), Quercetin (Q)-loaded MgFeO@Liposomes (Q-MLs) nano-hybrid system were successfully synthesized for magnetic hyperthermia (MHT) and SDD applications.

Effects of gamma radiation on the electrical properties of InAs/InGaAs quantum dot-based laser structures grown on GaAs and Si substrates by molecular beam epitaxy.

This study investigates the impact of gamma radiation on the electrical properties of InAs/InGaAs quantum dot-based laser structures grown on both GaAs (Sample A) and Si (Sample B) substrates using molecular beam epitaxy. The research explores the electrical characteristics of the lasers before and after being exposed to gamma radiation employing current-voltage (-), capacitance-voltage (-), deep level transient spectroscopy (DLTS) and Laplace DLTS techniques. The results show that the electrical properties of the lasers change due to gamma radiation exposure, and the extent of the change depends on the substrate used for growth.

Assessing the Heat Generation and Self-Heating Mechanism of Superparamagnetic FeO Nanoparticles for Magnetic Hyperthermia Application: The Effects of Concentration, Frequency, and Magnetic Field.

Magnetite nanoparticles (MNPs) exhibit favorable heating responses under magnetic excitation, which makes them particularly suited for various hyperthermia applications. Herein, we report the detailed self-heating mechanisms of MNPs prepared via the (KHB) methodology. The as-prepared MNPs were fully characterized using various spectroscopic techniques including transmission electron microscopy (TEM), dynamic light scattering (DLS), -ray diffraction (XRD), energy-dispersive -ray spectroscopy (EDX), and vibrating sample magnetometry (VSM).

New Organic-Inorganic Salt Based on Fluconazole Drug: TD-DFT Benchmark and Computational Insights into Halogen Substitution.

In this study, we report the synthesis of a new organic-inorganic molecular salt of the clinically used antifungal drug fluconazole, (H2Fluconazole).SnCl.2HO.

A Continuously Tunable Full-Color Emission Nitrogen-Doped Carbon Dots and for Ultrasensitive and Highly Selective Detection of Ascorbic Acid.

Nitrogen-doped carbon dots exhibiting excitation-dependent full-color emissions (F-NCDs) were prepared via the one-step hydrothermal method with citric acid and phenylenediamine. Specifically, the emission wavelength of the F-NCDs tuned from 452 nm to 602 nm due to the introduction of new energy levels by C=O and C=N functional groups. We exploited its stability in illumination, ionic strength, and pH, as well as its specificity, sensitivity, especially in ascorbic acid (AA) detection.

Maghemite (γ-FeO) and γ-FeO-TiO Nanoparticles for Magnetic Hyperthermia Applications: Synthesis, Characterization and Heating Efficiency.

In this report, the heating efficiencies of γ-FeO and hybrid γ-FeO-TiO nanoparticles NPs under an alternating magnetic field (AMF) have been investigated to evaluate their feasible use in magnetic hyperthermia. The NPs were synthesized by a modified sol-gel method and characterized by different techniques. X-ray diffraction (XRD), Mössbauer spectroscopy and electron microscopy analyses confirmed the maghemite (γ-FeO) phase, crystallinity, good uniformity and 10 nm core sizes of the as-synthesized composites.

Iron Oxide Mesoporous Magnetic Nanostructures with High Surface Area for Enhanced and Selective Drug Delivery to Metastatic Cancer Cells.

This work reports the fabrication of iron oxide mesoporous magnetic nanostructures (IO-MMNs) via the nano-replication method using acid-prepared mesoporous spheres (APMS) as the rigid silica host and iron (III) nitrate as the iron precursor. The obtained nanosized mesostructures were fully characterized by SEM, TEM, DLS, FTIR, XRD, VSM, and nitrogen physisorption. IO-MMNs exhibited relatively high surface areas and large pore volumes ( = 70-120 m/g and = 0.

[Cu(PhS)(BuNH)(H)] Reveals the Coexistence of Large Planar Cores and Hemispherical Shells in High-Nuclearity Copper Nanoclusters.

Copper-based nanomaterials have attracted tremendous interest due to their unique properties in the fields of photoluminescence and catalysis. As a result, studies on the correlation between their molecular structure and their properties are of great importance. Copper nanoclusters are a new class of nanomaterials that can provide an atomic-level view of the crystal structure of copper nanoparticles.

In deep evaluation of the neurotoxicity of orally administered TiO nanoparticles.

Titanium dioxide nanoparticles were widely used in food as dietary supplements, in drugs, in toothpaste, ect. Few numbers of studies were interested to the neurotoxicity of TiO NPs through oral pathway. The present study aims firstly to understand the connection between the physicochemical properties of TiO NPs and their associated toxicological oral pathway by evaluation the colloidal stability of TiO NPs over time in different media simulating physiological gastric, intestinal and serum conditions at 37 °C to be close to the oral administraton.

Multi-slice CT examinations of adult patients at Sudanese hospitals: radiation exposure based on size-specific dose estimates (SSDE).

The aim of this study was to update the radiation exposure for adult patients undergoing multi-slice CT (MSCT) examinations using size-specific dose estimates (SSDE). Console, displayed CTDI and scan parameters were retrospectively recorded for 423 adult patients in seven Sudanese hospitals. Patient torso diameters were measured using digital calipers on the scanner console.

The effect of titanium dioxide nanoparticles on neuroinflammation response in rat brain.

Titanium dioxide nanoparticles (TiO NPs) are widely used for their whiteness and opacity in several applications such as food colorants, drug additives, biomedical ceramic, and implanted biomaterials. Research on the neurobiological response to orally administered TiO NPs is still limited. In our study, we investigate the effects of anatase TiO NPs on the brain of Wistar rats after oral intake.